Alternative Dispute Resolution in Patent Controversies

Mr. Balmer relates how ADR allows attorneys to tailor rules to resolve disputes in light of, e.g., party relationships and internal dynamics. He notes that, for life to go on, having resolution is itself an important goal

Optimisation of the spark gap parameters for high powered ultrasound applications

There is considerable interest in the industrial and commercial applications of high power ultrasound (HPU) generated using pulsed power techniques. These applications include metal peening, the treatment of ores and minerals before extraction, drilling technologies and the comminution and recovery of waste materials. In all of these applications, it is important to optimise the parameters of the discharge causing the shock wave in the working medium to maximise the efficiency of the treatment. In a research project at the University of Strathclyde, some applications of HPU to the treatment of waste to assist in recycling have been investigated. Two systems have been considered, slag from the manufacture of stainless steel and bottle glass. With the slag material, it is intended to separate stainless steel from the silicate matrix to permit its recovery. With the bottle glass, the intention is comminution of the material to allow it to be recycled in a more valuable form. Measurements of the efficiency of these processes have been made in terms of the mass of material processed versus the energy input as the parameters of the discharge gap have been varied. In parallel with this work, measurements have been made using pinducer sensors to determine the energy in HPU pulses generated by discharges under identical conditions. Correlations are made between the efficiency of material treatment and the intensity of the HPU pulse measured in the far field. It is hoped that this approach will allow the optimal gap parameters to be determined using pinducer measurements rather than time consuming trials based around materials processing

Cementoblastoma in the Maxilla: A Case Report

The cementoblastoma is a rare, benign odontogenic tumour. It is generally asymptomatic and usually occurs in young adults. It is more common in males. It is most often associated with mandibular molar teeth and has a characteristic radiographic appearance. This case report is of a young male patient who presented with a cementoblastoma associated with a maxillary second molar. The initial presentation was to his dentist with pain, which was assumed to be of dental origin. This case highlights the importance of adequate radiographic investigation and appropriate interpretation in forming a diagnosis. It also serves as a reminder that rare odontogenic tumours may present initially in primary care and it is essential that all practitioners are aware of them. </jats:p

Germline mutations in retinoma patients: Relevance to low-penetrance and low-expressivity molecular basis

PURPOSE: To study phenotype-genotype correlation in patients who have retinoma, which is a benign tumor resembling the post irradiation regression pattern of retinoblastoma (RB). METHODS: We selected patients who had retinoma and positive family history for RB and patients who had retinoma in one eye and either retinoma or RB in the other eye. The study included 22 patients with available DNA: 18 from 11 families and four sporadic cases. DNA was extracted from peripheral blood leukocytes. The RB1 gene was screened by DHPLC and direct sequencing of the promoter and all the exons. RESULTS: We identified 17 occurrences of 11 distinct germline mutations in two sporadic and in 15 familial cases (nine families). The 11 identified mutations were located in exons 1, 10,11,13,14, and 19 to 23. Four of the identified mutations were not previously reported, including g.64407delT, g.153236A&gt;T, g.156743delTCTG, and g.162078delA. Eight out the 11 mutations were truncating and three were nontruncating (missense). There was no correlation between the type of mutation and the number of tumor foci per eye (RB or retinomas). Highly heterogeneous intrafamilial expressivity was observed. CONCLUSIONS: To our knowledge, this study is the largest series of mutations of consecutive retinoma patients. The present data suggest that the type of inherited mutations underlying retinoma is undistinguishable from RB related ones, i.e., largely dominated by truncating mutants. This finding is in contrast with the RB1 genotypic spectrum of mutations associated with low-penetrance RB, i.e., nontruncating mutants. The molecular mechanism underlying low-penetrance and attenuated expressivity (retinomas) appeared to be distinct

Transport behavior of holes in boron delta-doped diamond structures

Boron delta-doped diamond structures have been synthesized using microwave plasma chemical vapor deposition and fabricated into FET and gated Hall bar devices for assessment of the electrical characteristics. A detailed study of variable temperature Hall, conductivity, and field-effect mobility measurements was completed. This was supported by Schr€dinger-Poisson and relaxation time o calculations based upon application of Fermi’s golden rule. A two carrier-type model was developed with an activation energy of $0.2 eV between the delta layer lowest subband with mobility$1 cm2/Vs and the bulk valence band with high mobility. This new understanding of the transport of holes in such boron delta-doped structures has shown that although Hall mobility as high as 900 cm2/Vs was measured at room temperature, this dramatically overstates the actual useful performance of the device

Can crumb rubber modifier effectively replace the use of polymer- modified bitumen in asphalt mixture?

Laboratory scale mechanical performances on six plant produced mixtures; three semi-dense surface courses and three dense binder courses modified with engineered crumb rubber (ECR) using the dry process are presented. The two types of mixtures produced and investigated fulfilled for the most part, the requirements of the Swiss and/or US standards regarding volumetric properties, water sensitivity and rutting. In advanced testing where no requirements exist, the dense ECR mixtures performed similar to the reference polymer modified mixtures and slightly worse for semi-dense mixtures in high temperature tests, where the binder becomes viscous in the rubber-binder composite and its ability to transfer loads is reduced. The ECR mixtures performed similarly or better than the reference in low temperature tests.&nbsp; Across the advanced testing data set, all obtained results were well within acceptable values for both ECR and reference polymer mixtures indicating that crumb rubber can effectively replace polymer in asphalt mixtures