8 research outputs found
Taxonomic characterisation of ceftazidime-resistant Brevundimonas isolates and description of Brevundimonas faecalis sp. nov.
Rapid detection of pneumococcal antigen in lung aspirates: comparison with culture and PCR technique
Pesquisa de bactĂ©rias do gĂȘnero Vibrio em feridas cutĂąneas de pescadores do municĂpio de Raposa-MA
Sucrose-derived exopolysaccharides of Streptococcus mutans V403 contribute to infectivity in endocarditis
Summary
We used an isogenic mutant of Streptococcus mutans V403, which differs from the wildâtype V403 in genes involved in glucan and fructan production, to examine the importance of these exopolysaccharides as factors affecting infectivity in endocarditis. Rats inoculated with V403 developed endocarditis more frequently than animals inoculated with the mutant strain which produced neither glucan nor fructan (58% versus 12%, P<0.01). In phagocytosis assays, both strains were found to be associated with the human granulocytes but a greater number of live V403 than of mutant organisms could be recovered. Colony counts recovered from fibrin plates incubated with the mutant were lower than those incubated with V403. These experiments indicate that exopolysaccharides produced by Streptococcus mutans contribute to its infectivity in endocarditis