Un ambiente Web per la conversione di documenti TEI in formato RASH: progettazione ed implementazione

La tesi descrive la progettazione e l’implementazione di un sistema che permetta ad un utente di caricare documenti in formato TEI sulla piattaforma DocuDipity, un'applicazione Web per supportare l’esplorazione e l’analisi di documenti eterogenei. Affinché l’utente possa usufruire di tali funzionalità, è necessario convertire i documenti dell’utente in funzione dei requisiti di struttura e formato imposti dall’API di caricamento della piattaforma. A tal proposito, viene realizzata tei2rash, un’applicazione web che permette di convertire documenti in formato TEI nel formato richiesto RASH e di impacchettarli conformemente ai requisiti strutturali imposti. RASH (Research Articles in Semplified HTML) è un formato Web-First per la scrittura di articoli scientifici basati su HTML, mentre, TEI (Text Encoding Initiative) è un sistema di codifica SGML/XML per testi originariamente disponibili nella sola forma cartacea; entrambi vengono ampiamente discussi sottolineando i molteplici vantaggi derivanti dalla loro adozione. Inoltre, la tesi fornisce una panoramica relativa alla progettazione e all’implementazione dell’applicazione, evidenziando le problematiche riscontrate, i limiti, le scelte tecnologiche ed eventuali sviluppi futuri

Non-linear damping of superimposed primordial oscillations on the matter power spectrum in galaxy surveys

Galaxy surveys are an important probe for superimposed oscillations on the primordial power spectrum of curvature perturbations, which are predicted in several theoretical models of inflation and its alternatives. In order to exploit the full cosmological information in galaxy surveys it is necessary to study the matter power spectrum to fully non-linear scales. We therefore study the non-linear clustering in models with superimposed linear and logarithmic oscillations to the primordial power spectrum by running high-resolution dark-matter-only N-body simulations. We fit a Gaussian envelope for the non-linear damping of superimposed oscillations in the matter power spectrum to the results of the N-body simulations for k less than or similar to 0.6 h/Mpc at 0 <= z <= 5 with an accuracy below the percent. We finally use this fitting formula to forecast the capabilities of future galaxy surveys, such as Euclid and Subaru, to probe primordial oscillation down to non-linear scales alone and in combination with the information contained in CMB anisotropies

Photoidentification catalog of Cuvier's beaked whale (Ziphius cavirostris) in the Ligurian Sea

A photo-ID catalog of Cuvier's beaked whales was compiled by analyzing data collected in the Ligurian Sea from 1998 to 2007. Data were collected during dedicated surveys for beaked whales, opportunistic whale watching cruises, and during several tagging efforts. A total of 2,300 photographs was collected and referenced to time and GPS position. Of these photographs, 650 were of sufficient quality to use for photo-identification. Photographs were divided into four categories, based on scarring and pigmentation patterns: very distinctive (heavily scarred and/or bold pigmentation), distinctive (many distinct scars and/or bold pigmentation), slightly distinctive (few scars and lack of bold pigmentation), and not distinctive (no scars and solid brown animal). 127 individual whales were identified, of which 10 were classified as adult males, 3 as adult females, 3 as calves, and 27 as immature whales, based on the above criteria. An additional 26 whales were classified as possible males, and 28 as possible females. During the 9 year study period, 34 whales were resighted, and the longest time between resights was 7 years

First evidence of resistance to pyrethroid insecticides in Italian Aedes albopictus populations after 26 years since invasion

Aedes albopictus has spread during the last decades all over the world. This has increased significantly the risk of exotic arbovirus transmission (e.g. Chikungunya, Dengue, and Zika) also in temperate areas, as testified by the Chikungunya 2007- and 2017-outbreaks in north-east and central Italy. Insecticides represent a main tool for limiting the circulation of these mosquito-borne viruses. The aim of the present study is to start filling the current gap of knowledge on pyrethroid insecticide resistance of European Ae. albopictus populations focusing on populations from Italy, Albania and Greece

Mosquito-Borne Diseases and ‘One Health’: The Northwestern Italian Experience

In Italy, the surveillance of Mosquito-Borne Diseases (MBDs) is regulated by two national preparedness plans: (1) for West Nile and Usutu viruses, integrating human and veterinary surveillance in order to early detect viruses circulation and to quickly apply control measures aimed at reducing the risk of transmission through blood and blood components and (2) for Arbovirosis transmitted by Aedes mosquitoes, mainly Chikungunya, Dengue and Zika viruses, based on surveillance of both imported and autochthonous human cases. This chapter reports the results of the application of these National Plans in Northwestern Italy and their impact for human health. In detail, we present the coordinated activities enforced in Piemonte and Liguria Regions, as a good example of the ‘One Health approach’ to control MBDs and prevent human transmission

First evidence of pyrethroid resistance in Italian populations of West Nile virus vector Culex pipiens

13openInternationalItalian coauthor/editorCulex pipiens (Linnaeus), one of the most abundant mosquito species in Europe, plays a crucial role in the endemic transmission of West Nile virus and caused the large outbreak with >1600 human cases in 2018. Although evidence of resistance to pyrethroids has been reported for Cx. pipiens populations from Spain and Greece, resistance monitoring has been largely neglected in Italy. Herein, we investigate susceptibility of Italian Cx. pipiens populations to the pyrethroids permethrin and deltamethrin. Results from WHO-tube-bioassays revealed mortalities ranging from 14–54%, indicating high levels of resistance, in four out of 10 populations exposed to permethrin (0.75%) and of 63% in one of three populations exposed to deltamethrin (0.05%). Reduced susceptibility (mortality<98%) was detected in almost all other populations. A clear association is shown between the resistant phenotype and the presence of kdr-alleles in position 1014 of the VSSC, strongly suggesting its role in reducing susceptibility. The study provides the first evidence of pyrethroid-resistance in Italian Cx. pipiens populations and reports levels of resistance paralleled in the European region only in Turkey. This highlights the urgent need to implement insecticide-resistance management plans to restore the efficacy of the nowadays only chemical weapon available to control arbovirus transmission in Europe.openPichler, Verena; Giammarioli, Carola; Bellini, Romeo; Veronesi, Rodolfo; Arnoldi, Daniele; Rizzoli, Annapaola; Lia, Riccardo Paolo; Otranto, Domenico; Ballardini, Marco; Cobre, Pietro; Serini, Paola; Della Torre, Alessandra; Caputo, BeniaminoPichler, V.; Giammarioli, C.; Bellini, R.; Veronesi, R.; Arnoldi, D.; Rizzoli, A.; Lia, R.P.; Otranto, D.; Ballardini, M.; Cobre, P.; Serini, P.; Della Torre, A.; Caputo, B

Factors Associated With Severe Gastrointestinal Diagnoses in Children With SARS-CoV-2 Infection or Multisystem Inflammatory Syndrome

Importance Severe gastrointestinal (GI) manifestations have been sporadically reported in children with COVID-19; however, their frequency and clinical outcome are unknown. Objective To describe the clinical, radiological, and histopathologic characteristics of children with COVID-19 presenting with severe GI manifestations to identify factors associated with a severe outcome. Design, Setting, and Participants A multicenter retrospective cohort study (February 25, 2020, to January 20, 2021) enrolled inpatient and outpatient children (aged &lt;18 years) with acute SARS-CoV-2 infection, confirmed by positive real-time reverse-transcriptase–polymerase chain reaction on nasopharyngeal swab or fulfilling the US Centers for Disease Control and Prevention criteria for multisystem inflammatory syndrome in children (MIS-C). The study was conducted by pediatricians working in primary care or hospitals in Italy participating in the COVID-19 Registry of the Italian Society of Pediatric Infectious Diseases. Main Outcomes and Measures The occurrence of severe GI manifestations, defined by a medical and/or radiological diagnosis of acute abdomen, appendicitis (complicated or not by perforation and/or peritonitis), intussusception, pancreatitis, abdominal fluid collection, and diffuse adenomesenteritis requiring surgical consultation, occurring during or within 4 to 6 weeks after infection with SARS-CoV-2 infection. Logistic regression was used to estimate odds ratios (ORs) with 95% CIs of factors potentially associated with severe outcomes. Results Overall, 685 children (386 boys [56.4%]; median age, 7.3 [IQR, 1.6-12.4] years) were included. Of these children, 628 (91.7%) were diagnosed with acute SARS-CoV-2 infection and 57 (8.3%) with MIS-C. The presence of GI symptoms was associated with a higher chance of hospitalization (OR, 2.64; 95% CI, 1.89-3.69) and intensive care unit admission (OR, 3.90; 95% CI, 1.98–7.68). Overall, 65 children (9.5%) showed severe GI involvement, including disseminated adenomesenteritis (39.6%), appendicitis (33.5%), abdominal fluid collection (21.3%), pancreatitis (6.9%), or intussusception (4.6%). Twenty-seven of these 65 children (41.5%) underwent surgery. Severe GI manifestations were associated with the child’s age (5-10 years: OR, 8.33; 95% CI, 2.62-26.5; &gt;10 years: OR, 6.37; 95% CI, 2.12-19.1, compared with preschool-age), abdominal pain (adjusted OR [aOR], 34.5; 95% CI, 10.1-118), lymphopenia (aOR, 8.93; 95% CI, 3.03-26.3), or MIS-C (aOR, 6.28; 95% CI, 1.92-20.5). Diarrhea was associated with a higher chance of adenomesenteritis (aOR, 3.13; 95% CI, 1.08-9.12) or abdominal fluid collection (aOR, 3.22; 95% CI, 1.03-10.0). Conclusions and Relevance In this multicenter cohort study of Italian children with SARS-CoV-2 infection or MIS-C, 9.5% of the children had severe GI involvement, frequently associated with MIS-C. These findings suggest that prompt identification may improve the management of serious complications

la responsibilità sciistica

In the context of the legal discipline of civil liability, the subject of continuous debate and evolution, this volume aims to provide a picture as complete as possible of ski liability by dealing with the different profiles of responsibility: managers of skiable areas, users, ski instructors, subjects involved in the organization of competitive events. This collection of conference proceedings, in addition to the contributions of the speakers, contains important works by scholars and experts in the field.; Nell’ambito della disciplina giuridica della responsabilità civile, oggetto di continuo dibattito ed evoluzione, il presente volume mira a fornire un quadro quanto più possibilmente completo della responsabilità sciistica trattando i diversi profili di responsabilità: dei gestori delle aree sciabili, degli utenti, dei maestri di sci, dei soggetti coinvolti nella organizzazione di eventi agonistici. Questa raccolta di atti di convegno, oltre ai contributi dei relatori, contiene importanti lavori di studiosi ed esperti della materia

Diagnostic difficulties of Lactobacillus casei bacteraemia in immunocompetent patients: A case report

This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens