2,405 research outputs found
Matching bias in syllogistic reasoning: Evidence for a dual-process account from response times and confidence ratings
We examined matching bias in syllogistic reasoning by analysing response times, confidence ratings, and individual differences. Robertsâ (2005) ânegations paradigmâ was used to generate conflict between the surface features of problems and the logical status of conclusions. The experiment replicated matching bias effects in conclusion evaluation (Stupple & Waterhouse, 2009), revealing increased processing times for matching/logic âconflict problemsâ. Results paralleled chronometric evidence from the belief bias paradigm indicating that logic/belief conflict problems take longer to process than non-conflict problems (Stupple, Ball, Evans, & Kamal-Smith, 2011). Individualsâ response times for conflict problems also showed patterns of association with the degree of overall normative responding. Acceptance rates, response times, metacognitive confidence judgements, and individual differences all converged in supporting dual-process theory. This is noteworthy because dual-process predictions about heuristic/analytic conflict in syllogistic reasoning generalised from the belief bias paradigm to a situation where matching features of conclusions, rather than beliefs, were set in opposition to logic
Time After Time
VERSE 1What can I do to wake youUp to the things you miss?What can I do to make youThrill to an honest kiss?What can I do that I havenât doneTo make you believeI love only one!
CHORUSTime after time Iâve told youHow much I miss your smile;Hoping youâd let me hold youJust for a little while.Time after time you refuse me,Refuse me your lips sublime,You donât seem to know that I love you so,Thoâ Iâve told you time after time.
VERSE 2Is there no love comes stealingInto your sleeping heart?Is there no lonesome feelingFills you when weâre apart?Is there no way to win your dear hand?What more can I say,So youâll understand?
CHORU
The intersection between Descriptivism and Meliorism in reasoning research: further proposals in support of âsoft normativismâ
The rationality paradox centers on the observation that people are highly intelligent, yet show evidence of errors and biases in their thinking when measured against normative standards. Elqayam and Evansâ (2011) reject normative standards in the psychological study of thinking, reasoning and deciding in favor of a âvalue-freeâ descriptive approach to studying high-level cognition. In reviewing Elqayam and Evansâ (2011) position, we defend an alternative to descriptivism in the form of âsoft normativism,â which allows for normative evaluations alongside the pursuit of descriptive research goals. We propose that normative theories have considerable value provided that researchers: (1) are alert to the philosophical quagmire of strong relativism; (2) are mindful of the biases that can arise from utilizing normative benchmarks; and (3) engage in a focused analysis of the processing approach adopted by individual reasoners. We address the controversial âisâoughtâ inference in this context and appeal to a âbridging solutionâ to this contested inference that is based on the concept of âinformal reflective equilibrium.â Furthermore, we draw on Elqayam and Evansâ (2011) recognition of a role for normative benchmarks in research programs that are devised to enhance reasoning performance and we argue that such Meliorist research programs have a valuable reciprocal relationship with descriptivist accounts of reasoning. In sum, we believe that descriptions of reasoning processes are fundamentally enriched by evaluations of reasoning quality, and argue that if such standards are discarded altogether then our explanations and descriptions of reasoning processes are severely undermined
MRI radiomic features are independently associated with overall survival in soft tissue sarcoma
Purpose: Soft tissue sarcomas (STS) represent a heterogeneous group of diseases, and selection of individualized treatments remains a challenge. The goal of this study was to determine whether radiomic features extracted from magnetic resonance (MR) images are independently associated with overall survival (OS) in STS.
Methods and Materials: This study analyzed 2 independent cohorts of adult patients with stage II-III STS treated at center 1 (N = 165) and center 2 (N = 61). Thirty radiomic features were extracted from pretreatment T1-weighted contrast-enhanced MR images. Prognostic models for OS were derived on the center 1 cohort and validated on the center 2 cohort. Clinical-only (C), radiomics-only (R), and clinical and radiomics (C+R) penalized Cox models were constructed. Model performance was assessed using Harrell\u27s concordance index.
Results: In the R model, tumor volume (hazard ratio [HR], 1.5) and 4 texture features (HR, 1.1-1.5) were selected. In the C+R model, both age (HR, 1.4) and grade (HR, 1.7) were selected along with 5 radiomic features. The adjusted c-indices of the 3 models ranged from 0.68 (C) to 0.74 (C+R) in the derivation cohort and 0.68 (R) to 0.78 (C+R) in the validation cohort. The radiomic features were independently associated with OS in the validation cohort after accounting for age and grade (HR, 2.4;
Conclusions: This study found that radiomic features extracted from MR images are independently associated with OS when accounting for age and tumor grade. The overall predictive performance of 3-year OS using a model based on clinical and radiomic features was replicated in an independent cohort. Optimal models using clinical and radiomic features could improve personalized selection of therapy in patients with STS
Reversal of graft-versus-host disease with infusion of autologous bone marrow
Graft-versus-host disease (GVHD) remains a major complication of bone marrow transplantation. This report describes reversal of GVHD by infusion of stored recipient bone marrow following combined liver-bone marrow allotransplantation. Graft-versus-host disease developed at the end of the first postoperative week. The skin involvement progressively spread to approximately 80% of the body surface and was not affected by modification of the immunosuppressive treatment. On the 42nd and 43rd postoperative day 1.23 à 108 and 1.6 à 108 autologous bone marrow cells per kg of recipient body weight were infused. The skin rush began to dramatically improve and resolved within 2 wk from the autologous marrow infusion. Autologous bone marrow storage previous to allogeneic bone marrow transplantation for tolerance induction could constitute a safety net in case of occurrence of GVHD. © 1994
A T8.5 Brown Dwarf Member of the Xi Ursae Majoris System
The Wide-field Infrared Survey Explorer has revealed a T8.5 brown dwarf (WISE
J111838.70+312537.9) that exhibits common proper motion with a
solar-neighborhood (8 pc) quadruple star system - Xi Ursae Majoris. The angular
separation is 8.5 arc-min, and the projected physical separation is about 4000
AU. The sub-solar metallicity and low chromospheric activity of Xi UMa A argue
that the system has an age of at least 2 Gyr. The infrared luminosity and color
of the brown dwarf suggests the mass of this companion ranges between 14 and 38
Jupiter masses for system ages of 2 and 8 Gyr respectively.Comment: AJ in press, 12 pages LaTeX with 6 figures. More astrometric data and
a laser guide star adaptive optics image adde
Reversal of Graft-Versus-Host Disease with Infusion of Stored Autologous Bone Marrow Cells Following Combined Liver-Bone Marrow Allotransplantation in Man.
Developing and enhancing biodiversity monitoring programmes: a collaborative assessment of priorities
1.Biodiversity is changing at unprecedented rates, and it is increasingly important that these changes are quantified through monitoring programmes. Previous recommendations for developing or enhancing these programmes focus either on the end goals, that is the intended use of the data, or on how these goals are achieved, for example through volunteer involvement in citizen science, but not both. These recommendations are rarely prioritized.
2.We used a collaborative approach, involving 52 experts in biodiversity monitoring in the UK, to develop a list of attributes of relevance to any biodiversity monitoring programme and to order these attributes by their priority. We also ranked the attributes according to their importance in monitoring biodiversity in the UK. Experts involved included data users, funders, programme organizers and participants in data collection. They covered expertise in a wide range of taxa.
3.We developed a final list of 25 attributes of biodiversity monitoring schemes, ordered from the most elemental (those essential for monitoring schemes; e.g. articulate the objectives and gain sufficient participants) to the most aspirational (e.g. electronic data capture in the field, reporting change annually). This ordered list is a practical framework which can be used to support the development of monitoring programmes.
4.People's ranking of attributes revealed a difference between those who considered attributes with benefits to end users to be most important (e.g. people from governmental organizations) and those who considered attributes with greatest benefit to participants to be most important (e.g. people involved with volunteer biological recording schemes). This reveals a distinction between focussing on aims and the pragmatism in achieving those aims.
5.Synthesis and applications. The ordered list of attributes developed in this study will assist in prioritizing resources to develop biodiversity monitoring programmes (including citizen science). The potential conflict between end users of data and participants in data collection that we discovered should be addressed by involving the diversity of stakeholders at all stages of programme development. This will maximize the chance of successfully achieving the goals of biodiversity monitoring programmes
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