3,766 research outputs found
Revisiting the 18th century sublime in contemporary visual art:representations of Icelandic landscape
This thesis discusses the depiction of the landscape in art in relation to the theory of the sublime, through my own artistic practice, and through the examination of examples from the history of art. The theory of the Sublime is also analysed in the historical context of the18th century, and discussed in relation to its place, and relevance in contemporary ideas and art production.
The thesis begins by examining Edmund Burke’s Philosophical Enquiry into the origin of our ideas of the Sublime and Beautiful, and using this to explore how artists have responded to the Sublime in their paintings, examining the work of Turner and Caspar David Friedrich for example, as major exponents of the Sublime. I set out to establish whether or not the emotional qualities that the eighteenth-century idea of the Sublime uncovers, can be effectively defined by this term in contemporary painting.
Alongside this, my thesis also deals with my own personal experience of the Sublime, as identified in the glacial landscapes of Iceland. The Sublime is a key influence in my artistic practice.
My paintings might be seen as a direct response to feelings associated with the Sublime experienced in the glacial landscapes of Iceland, and through the process of making them I have attempted to explore and translate my sublime experience
Ion-scale spectral break of solar wind turbulence at high and low beta
The power spectrum of magnetic fluctuations in the solar wind at 1 AU displays a break between two power laws in the range of spacecraft-frame frequencies 0.1 to 1 Hz. These frequencies correspond to spatial scales in the plasma frame near the proton gyroradius ρi and proton inertial length di. At 1 AU it is difficult to determine which of these is associated with the break, since [Formula: see text] and the perpendicular ion plasma beta is typically β⊥i∼1. To address this, several exceptional intervals with β⊥i≪1 and β⊥i≫1 were investigated, during which these scales were well separated. It was found that for β⊥i≪1 the break occurs at di and for β⊥i≫1 at ρi, i.e., the larger of the two scales. Possible explanations for these results are discussed, including Alfvén wave dispersion, damping, and current sheets
Solar Wind Electric Fields in the Ion Cyclotron Frequency Range
Measurements of fluctuations of electric fields in the frequency range from a
fraction of one Hz to 12.5 Hz are presented, and corrected for the Lorentz
transformation of magnetic fluctuations to give the electric fields in the
plasma frame. The electric fields are large enough to provide the dominant
force on the ions of the solar wind in the region near the ion cyclotron
frequency of protons, larger than the force due to magnetic fluctuations. They
provide sufficient velocity space diffusion or heating to counteract
conservation of magnetic moment in the expanding solar wind to maintain nearly
isotropic velocity distributions
Detailed Structure and Dynamics in Particle-in-Cell Simulations of the Lunar Wake
The solar wind plasma from the Sun interacts with the Moon, generating a wake
structure behind it, since the Moon is to a good approximation an insulator,
has no intrinsic magnetic field and a very thin atmosphere. The lunar wake in
simplified geometry has been simulated via a 1-1/2-D electromagnetic
particle-in-cell code, with high resolution in order to resolve the full phase
space dynamics of both electrons and ions. The simulation begins immediately
downstream of the moon, before the solar wind has infilled the wake region,
then evolves in the solar wind rest frame. An ambipolar electric field and a
potential well are generated by the electrons, which subsequently create a
counter-streaming beam distribution, causing a two-stream instability which
confines the electrons. This also creates a number of electron phase space
holes. Ion beams are accelerated into the wake by the ambipolar electric field,
generating a two stream distribution with phase space mixing that is strongly
influenced by the potentials created by the electron two-stream instability.
The simulations compare favourably with WIND observations.Comment: 10 pages, 13 figures, to be published in Physics of Plasma
Estimating the cost-effectiveness of fluticasone propionate for treating chronic obstructive pulmonary disease in the presence of missing data
Objectives: To explore the cost-effectiveness of fluticasone propionate (FP) for the treatment of chronic obstructive pulmonary disease (COPD), we estimated costs and qualityadjusted life-years (QALYs) over 3 years, based on an economic appraisal of a previously reported clinical trial
(Inhaled Steroids in Obstructive Lung Disease in Europe [ISOLDE]).
Methods: Seven hundred forty-two patients enrolled in the ISOLDE trial who received either FP or placebo had data available on health-care costs and quality of life over the period of the study. The SF-36-based utility scores for quality
of life were used to calculate QALYs. A combined imputation and bootstrapping procedure was employed to handle missing data and to estimate statistical uncertainty in the estimated
cumulative costs and QALYs over the study period.
The imputation approach was based on propensity scoring and nesting this approach within the bootstrap ensured that multiple imputations were performed such that statistical estimates included imputation uncertainty.
Results: Complete data were available on mortality within the follow-up period of the study and a nonsignificant trend toward improved survival of 0.06 (95% confidence interval [CI] –0.01 to 0.15) life-years was observed. In an analysis based on a propensity scoring approach to missing data we estimated the incremental costs of FP versus placebo to be £1021 (95% CI £619–1338) with an additional effect of 0.11 QALYs (CI 0.04–0.20). Cost-effectiveness estimates
for the within-trial period of £17,700 per life-year gained (£6900 to ∞) and £9500 per QALY gained (CI £4300–26,500) were generated that include uncertainty due to the imputation process. An alternative imputation approach did
not materially affect these estimates.
Conclusions: Previous analyses of the ISOLDE study
showed significant improvement on disease-specific health status measures and a trend toward a survival advantage for treatment with FP. This analysis shows that joint considerations
of quality of life and survival result in a substantial increase in QALYs favoring treatment with FP. Based on these data, the inhaled corticosteroid FP appears costeffective for the treatment of COPD. Confirmation or refutation
of this result may be achieved once the Towards a
Revolution in COPD Health (TORCH) study reports, a large randomized controlled trial powered to detect mortality changes associated with the use of FP alone, or in combination with salmeterol, which is also collecting resource use and utility data suitable for estimating cost-effectiveness
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