Influence of Opening and Boundary Conditions on the Behavior of Concrete Hollow Block Walls: Experimental Results

The assembled pattern of concrete hollow building blocks contributes to the wall structure’s durability. This paper presents experimental research on the behavior of concrete hollow block walls. The experimental work included testing four concrete hollow block wall panels with different opening sizes. Constant vertical axial load was applied on top of the wall panels until failure, characterized by boundary conditions. The results showed that the presence of openings reduced the strength of the wall panels; it was possible to observe these differences since the opening area was between 20 and 40% of the gross wall panel area. It was also observed that while the opening percentage had a significant impact on the strength of the wall, the boundary conditions had a less substantial impact on the overall wall response. A high localized concentration of stress was observed at the top corners of the wall panels and a high stress concentration was also observed along the vertical sides of the openings. Variation in the number and the shape of the openings often changed the failure mechanism in the wall panels, even when the percentage area of the opening remained constant. The wall panels A1-B2 reached peak stress levels at 0.019 MPa, 0.036 MPa, 0.056 MPa, and 0.030 MPa. The equivalent peak strains were 0.018, 0.011, 0.012, and 0.010 respectively. This research established significant data and is expected to help in the design and analysis of axially loaded unreinforced masonry walls with openings

Intrauterine Tamponade Balloon for Management of Severe Postpartum Haemorrhage: Does Early Insertion Change the Outcome? A Retrospective Study on Blood Loss

The French College of Gynecologists and Obstetricians (CNGOF) recommends the use of intrauterine tamponade balloon (IUTB) in postpartum haemorrhage for bleeding that is refractory after sulprostone before either surgery or interventional radiology. However, the elapsed time between uterotonic drug injection and the insertion of intrauterine tamponade balloon was not reliably assessed. Objective: To evaluate the role of the timing of IUTB insertion and to assess the correlation between the time of insertion and outcome. Methods: A retrospective study in two tertiary care centres, including patients transferred for severe PPH management. Results: A total of 81 patients were included: 52 patients with IUTB inserted before 15 min (group 1) and 29 patients with IUTB inserted after 15 min (group 2). The mean volume of blood loss in the group of patients with IUTB inserted before 15 min was significantly lower than in group of patients with IUTB set after 15 min. Conclusion: An IUTB could be inserted simultaneously with a uterotonic agent, within 15 min and not after 15 min as suggested by local guidelines, but further prospective studies are required to confirm this

Finite element analysis of conceptual lumbar spine for different lifting position

The Lower-back pain (LBP) which is caused by lifting loads manually is one of the common issues faced by industrial workers. The objective of this paper is to determined the maximum stress and displacement on human lumbar by using computer aided engineering (CAE) software called Msc. Patran/Nastran. The 3D modeling of the lumbar spine from transferring data points of 3D scanner is reconstructed. The stress used for lifting loads from 20 to 60 kg is ranging between 2.52 to 74.1 MPa. The results showed that the end plate at 5th lumbar is experiencing the maximum stress development. This analysis is relevant to the industries especially manufacturing sector in order to provide a direction for ergonomists in the modification of jobs for workers who perform manual lifting. In order to gain a higher precision, it is suggested in the future that the lumbar spine is to be built based directly on a loaded CT scan and biodynamic loading situation with vibration and impact

Effect of surface density silver nanoplate films toward surface-enhanced Raman scattering enhancement for bisphenol A detection

Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI.This paper reports a study on surface-enhanced Raman scattering (SERS) phenomenon of triangular silver nanoplate (NP) films towards bisphenol A (BPA) detection. The NP films were prepared using self-assembly technique with four different immersion times; 1 hour, 2 hours, 5 hours, and 8 hours. The SERS measurement was studied by observing the changes in Raman spectra of BPA after BPA absorbed on the NP films. It was found that the Raman intensity of BPA peaks was enhanced by using the prepared SERS substrates. This is clearly indicated that these SERS silver substrates are suitable to sense industrial chemical and potentially used as SERS detector. However, the rate of SERS enhancement is depended on the distribution of NP on the substrate surface

A Multi - Centered Study Of The Influence Of Hiv Infection On The Transmission Of Tuberculosis To Household Contacts Three States Of Malaysia.

A multi-centered cross-sectional study was carried out to examine tuberculin (Mantoux) response among household contacts of pulmonary TB (PTB) patients registered in Kota Bharu Hospital, Kelantan; Alor Setar Hospital Kedah and Institute of Respiratory Medicine, Kuala Lumpur from year 2000 through 2004

Direct deposition of silver nanoplates on quartz surface by sequence pre-treatment hydroxylation and silanisation

This is an open access article under the CCBY license (http://creativecommons.org/ licenses/by/4.0/).Silver nanoparticles deposited on quartz substrates are widely used as SERS substrates. The nanoparticles can be deposited directly from colloidal solution by dipping technique. However, the adhesion of the particles on the quartz surface is very poor. Normally the substrate is pre-treated with hydroxylation or silanisation process. In this paper, we have demonstrated that the application of the sequence pre-treatment hydroxylation and silanisation have improved the density of silver nanoplates desposited on the quartz surface. • Sequence hydroxylation and silanisation pre-treatment assists the deposition of the nanoplate on the surface. • Various immersion times of the quartz surface into the colloidal nanoplates determined size distributions and density surface of the nanoplates on the surface. Method name Direct deposition of colloidal silver nanoplates on quartz surface using a self–assembly techniqu

Community empowerment for malaria control and prevention in Kampung Tong Nibong, Sarawak: an intervention study

Introduction Tong Nibong is a Bidayuh village located at Sarawak Kalimantan border. Since the year 2004 to 2009, a total of 537 cases of malaria were recorded in Serian District of which 14 cases were reported from Kampung Tong Nibong. Community empowerment programme for malaria infection prevention showed tremendous improvement in implementation. This intervention study aims to gauge the effectiveness of community empowerment approach in malaria elimination programme in Kampung Tong Nibong Serian. Methods An intervention study was conducted with pre and post data collection. Data was collected using validated questionnaire by face to face interview. Universal sampling method was used to select respondents from head of household and post data was collected after intervention activities were carried out within a year of study period. Results The study showed significant difference on level of knowledge of respondents on vector of malaria between pre and post data with a P < 0.05. There was significant difference between pre and post data on practices on control and prevention of malaria with a P < 0.05. The same goes to level of positive attitude of respondents towards malaria control. Conclusions In conclusion, the study can be considered successful because there is significant difference in knowledge, attitude and practice among the respondents between pre and post data. This indicates that community empowerment (voluntary participation) measures can be implemented in high risk or endemic areas where malaria is a persistent problem to the community and health institutions faces many limiting factors

Plasmodium malariae infections as a cause of febrile disease in an area of high Plasmodium falciparum transmission intensity in Eastern Uganda.

BACKGROUND: Plasmodium falciparum is responsible for the vast majority of (severe) clinical malaria cases in most African settings. Other Plasmodium species often go undiagnosed but may still have clinical consequences. CASE PRESENTATION: Here, five cases of Plasmodium malariae infections from Eastern Uganda (aged 2-39 years) are presented. These infections were all initially mistaken for P. falciparum, but Plasmodium schizonts (up to 2080/µL) were identified by microscopy. Clinical signs included history of fever and mild anaemia. CONCLUSION: These findings highlight the importance of considering non-falciparum species as the cause of clinical malaria. In areas of intense P. falciparum transmission, where rapid diagnostic tests that detect only P. falciparum antigens are commonly used, non-falciparum malaria cases may be missed

Prolyl-4-hydroxylase 3 maintains β-cell glucose metabolism during fatty acid excess in mice

The α-ketoglutarate–dependent dioxygenase, prolyl-4-hydroxylase 3 (PHD3), is an HIF target that uses molecular oxygen to hydroxylate peptidyl prolyl residues. Although PHD3 has been reported to influence cancer cell metabolism and liver insulin sensitivity, relatively little is known about the effects of this highly conserved enzyme in insulin-secreting β cells in vivo. Here, we show that the deletion of PHD3 specifically in β cells (βPHD3KO) was associated with impaired glucose homeostasis in mice fed a high-fat diet. In the early stages of dietary fat excess, βPHD3KO islets energetically rewired, leading to defects in the management of pyruvate fate and a shift from glycolysis to increased fatty acid oxidation (FAO). However, under more prolonged metabolic stress, this switch to preferential FAO in βPHD3KO islets was associated with impaired glucose-stimulated ATP/ADP rises, Ca(2+) fluxes, and insulin secretion. Thus, PHD3 might be a pivotal component of the β cell glucose metabolism machinery in mice by suppressing the use of fatty acids as a primary fuel source during the early phases of metabolic stress

Detoxification related genes in gut of Coptotermes curvignathus

Coptotermes curvignathus (C. curvignathus) are subterranean termites that feed on living-tree as their sole diet,which consist mainly of cellulose, hemicelluloses, lignin, plant allele chemical and other environmental residues such as insecticide. The xenobiotic compounds, plant allele chemical and insecticide are hazardous to termites health and need to be transported out of their body via xenobiotic and detoxification metabolism. This paper highlighted the potential enzymes that play vital role in the xenobiotic and detoxification metabolism. Transcriptomic data were generated from 200 termite’s digestive system using Illumina HiSeq 2000. Raw data was trimmed and assembled by SOLEXAQA and Bowtie before loaded into Gene Ontology based data mining software, Blast2GO (B2G). The result showed that, C. curvignathus contain enzymes that involved in all three biotransformation phases of xenobiotic and detoxification metabolism, which included cytochrome P450s monooxygenases, glutathione S-transferase, carboxylesterase, UDPglucuronyltransferases and N-acetyltransferase. The result of this study is the first insight into Cc xenobiotic pathway