Genetic diversity evaluation of Cumin (Cumin cyminum L.) based on phenotypic characteristics.

In order to assess the genetic diversity of cumin and determine the traits effective on seed yield and cumin- aldehyde, forty nine cumin ecotypes which they are sub-populations belonged to nine populations from different provinces of Iran were evaluated based on morphological and biochemical traits. Results indicated a significant variation for all the measured traits among and within populations derived from different provinces. Kerman and Esfahan populations showed the best performance based on the phenotypic data, while Yazd had almost the lowest levels of traits. Correlation analysis showed number of seed per umbel and umbel per plant had highest relationship with seed yield. Path analysis also demonstrated that number of umbel per plant and number of seed per umbel had the most direct effects on seed yield and were identified as the most effective factors on seed yield. Cumin aldehyde was mostly correlated by number of umbel per plant. The present study showed that different qualitative characteristics such as seeds with light color and without trichome and leaves without trichome, alternate and large pods of Petiole tend to produce high seed yield. Pattern analysis of different populations based on first two main principal components categorized the measured genotypes in to three groups: Pars, Northern_Khorasan, Golestan, Semnan and Yazd (Group1), Southern_Khorasan and Khorasan_Razavi (Group2) Kerman and Esfahan (Group3), which the third group are high yielding genotypes with different genetic background can be advised for cultivation and breeding programs. So the available genetic diversity among the Iranian cumin populations can be lead to produce high yielding population of cumin

Gas type identification at constant concentration level by system identification technique

The purpose of this paper is to explore the ability of the system identification technique in detecting a specific gas at a constant concentration level by a single sensor. Metal oxide semiconductor (MOS) gas sensor is used due to its wide range of applicability in gas monitoring systems. Using the Batch computer method, 115 outputs were recorded with sampling time of 0.57 Sec at a concentration level of 2600 (ppm) for Methanol, Ethanol, and Betanol gases. Applying the estimated model, each gas was successfully distinguished

Application of a sensor array based on capillary-attached conductive gas sensors for odor identification

An electronic nose based on an array of capillary-attached conductive gas sensors was fabricated. The identification ability of the developed structure was investigated by employing different categories of simple and complex odor databases. Feature data sets were generated from the dynamic and steady state responses of the sensor array to the applied odor databases. Combinations of different feature extraction and classification methods were used to detect target gases. Validation of each technique was evaluated. Achievements of the study proved high classification rates of the fabricated e-nose in odor identification. It was indicated that gas identification is possible by applying the early selected portion of transient responses of the developed sensor array. The ability of the mentioned structure in analyzing gas mixtures was also investigated. The results presented high accuracy in the classification of gas mixtures

Hydrogen detection in organic gas mixtures based on analyzing the transient response.

Purpose – The purpose of this paper is to explore the ability of capillary-attached gas sensor (CGS) in detecting components of gas mixtures, including a volatile organic gas and hydrogen in a wide range of concentrations. Design/methodology/approach – Diverse feature extraction and classification techniques were employed to analyze the response of CGS when applied to different mixtures. Findings – It was observed that the response of CGS to the above gas mixtures could be distinguishable. While evaluating the results of the classification technique, it was implied that hydrogen, in the presence of the volatile organic gases, could be detected perfectly by analyzing the response of the CGS. Separating techniques, which yielded a high rate of classification, were used to separate mixtures containing hydrogen and organic gases from other organic gas mixtures without hydrogen. Originality/value – The results presented in this paper prove the ability of CGS in fabricating an olfactory machine for analyzing the components of gas mixtures

The Effect of Aromatherapy with Citrus aurantium Aroma on Pain after Orthopedic Surgery: A Randomized Clinical Trial

Introduction: Postoperative pain is one of the most common physiological and psychological stress in patients that disrupts body function and can endanger patients’ health. This study aims to determine the effect of aromatherapy with Citrus aurantium essential on pain after orthopedic surgery. Methods: This randomized clinical trial was performed on 60 candidates for orthopedic surgery. Patients were selected through convenience sampling and divided into intervention and control groups through randomized block allocation. If the visual analogue scale (VAS) score was above 3, patients in the intervention group received aromatherapy with C. aurantium essential and the patients in the control group received a placebo (almond oil). VAS was used to measure pain. Data analysis was performed using independent t test, paired t test, and analysis of variance with repeated measures using SPSS software version 13. Results: Mean (SD) of pain intensity after intervention in experimental and control groups within 4, 8, and 12 hours after surgery was 7.30 (1.23) vs. 7.90 (0.99), 5.30 (0.98) versus 5.53 (0.68) and 2.53 (0.9) vs. 3.60 (0.77) respectively. The findings indicated that there was a significant difference in mean pain intensity between the experimental and control groups at 4 and 12 hours after surgery. Use of analysis of variance with repeated measures test with taking into account the interaction of time and group also showed a significant difference in mean pain intensity between the two experimental and control groups. Conclusion: Aromatherapy with Citrus aurantium essential can be effective in reducing mild to moderate pain after orthopedic surgery. Further studies are recommended to confirm this finding

Real-Time Gas Identification by Analyzing the Transient Response of Capillary-Attached Conductive Gas Sensor

In this study, the ability of the Capillary-attached conductive gas sensor (CGS) in real-time gas identification was investigated. The structure of the prototype fabricated CGS is presented. Portions were selected from the beginning of the CGS transient response including the first 11 samples to the first 100 samples. Different feature extraction and classification methods were applied on the selected portions. Validation of methods was evaluated to study the ability of an early portion of the CGS transient response in target gas (TG) identification. Experimental results proved that applying extracted features from an early part of the CGS transient response along with a classifier can distinguish short-chain alcohols from each other perfectly. Decreasing time of exposition in the interaction between target gas and sensing element improved the reliability of the sensor. Classification rate was also improved and time of identification was decreased. Moreover, the results indicated the optimum interval of the early transient response of the CGS for selecting portions to achieve the best classification rates

Evaluation of dimension effects on a capillary-attached gas sensor

The analysis and useful gas sensing properties of a capillary-attached gas sensor (CGS) have been recently investigated. The aim of the present work was the assessment of dimension effects on the CGS sensing properties both diameterwise and lengthwise. CGS samples in different dimensions were fabricated and tested by exposure to different target gases in different concentration ranges. Dimension effects on CGS properties such as selectivity, sensitivity, rise time and input range were investigated. It was observed that the CGS with smaller diameter and longer lengths generated more selective information. However, decreasing sensitivity and increasing minimum input range were some disadvantages of smaller diameters. Longer length also made longer rise time and slower sensor. Finally, the optimum ranges for the CGS in length and diameter were suggested

Comparison of cytotoxicity of Miltefosine and its niosomal form on chick embryo model

© 2024 The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY), https://creativecommons.org/licenses/by/4.0/Various drugs have been used for the treatment of leishmaniasis, but they often have adverse effects on the body's organs. In this study, we aimed to explore the effects of one type of drug, Miltefosine (MIL), and its analogue or modifier, liposomal Miltefosine (NMIL), on several fetal organs using both in silico analysis and practical tests on chicken embryos. Our in silico approach involved predicting the affinities of MIL and NMIL to critical proteins involved in leishmaniasis, including Vascular Endothelial Growth Factor A (VEGF-A), the Kinase insert domain receptor (KDR1), and apoptotic-regulator proteins (Bcl-2-associate). We then validated and supported these predictions through in vivo investigations, analyzing gene expression and pathological changes in angiogenesis and apoptotic mediators in MIL- and NMIL-treated chicken embryos. The results showed that NMIL had a more effective action towards VEGF-A and KDR1 in leishmaniasis, making it a better candidate for potential operative treatment during pregnancy than MIL alone. In vivo, studies also showed that chicken embryos under MIL treatment displayed less vascular mass and more degenerative and apoptotic changes than those treated with NMIL. These results suggest that NMIL could be a better treatment option for leishmaniasis during pregnancy.Peer reviewe