14 research outputs found

    Betawi Ulama's Perception of The XXI Century Against Contraception Law Controversy in Population Control

    Get PDF
    Legal issues regarding contraception and population control efforts to limit births and reduce overcrowding have not been without controversy. Differences in using naqli arguments and scientific, medical, and even political arguments make the discourse on family planning still hotly debated. This research will identify how Betawi Ulama's response in the XXI century to the law on the use of contraceptives and birth control through population control, along with the arguments and legal methods, they used to analyze the factors behind it and collect theoretical and empirical data related to social impacts/implications, from the Betawi Ulama's response to enacting the law on contraception and population control. The conclusion of this study will explain the positions, thoughts, and religious perspectives of Betawi Ulama in understanding various problems of Islamic law. Tend to think that is exclusive, inclusive, or moderate, especially in addressing the controversies of family planning law? This study took the capital city of DKI Jakarta as the sampling location, considering that the densest population in the country is in Jakarta, and it is very heterogeneous in terms of diversity and community characteristics. Population census data in 2010 shows that the capital city of DKI Jakarta is the largest city with the most populous population in Indonesia, around 9.6 million people. This research uses logical thinking, analysis with logic, induction, deduction, analogy, comparison and the like. The data in this study will be obtained through observation techniques, in-depth interviews with resource persons, and documentation

    Molecular docking studies of selected medicinal drugs as dengue virus-2 protease inhibitors

    Get PDF
    Dengue is a potentially deadly disease with no effective drug. An in silico molecular docking was performed using Autodock 4.2.6 to investigate the molecular interactions between protease inhibitors, comprising antibiotic derivatives namely doxycycline (3), rolitetracycline (5) and a non-steroidal anti-inflammatory drug (NSAID), meclofenamic acid (4), against the NS2B-NS3 protease from dengue virus-2 (DENV-2). The non-competitive inhibitor (3) showed lower binding energy (-5.15 kcal/mol) than the predicted competitive inhibitors 4 and 5 (-3.64 and -3.21 kcal/mol, respectively). Structural analyses showed compound 3 that bound to a specific allosteric site, interacted with Lys74, a significant amino acid residue bonded to one of the catalytic triad, Asp75. Compounds 4 and 5 showed direct binding with two of the catalytic triad, His51 and Ser135, hence, predicted to be competitive inhibitors

    The Impact of Diluted Detergents on Escherichia coli K12 (JM109)

    Get PDF
    The purpose of this study is to investigate the effect of diluted detergents namely, Clorox, Dettol and Aganol against Escherichia coli K12 (JM109), at different concentrations. Frequent usage of diluted detergents and disinfectants without knowing their effectiveness in killing microbes can act as a medium for infections in susceptible hosts. Moreover, it is known that the regular application of diluted detergents and disinfectants may actually cause antibiotic resistance. The efficacy of diluted detergents is determined by the minimum inhibition concentration (MIC) and the minimum bactericidal concentration (MBC) using tube dilution assay. The susceptibility test is conducted using the disc diffusion technique. Dettol and Clorox exhibited effective bacteriostatic agents where the MIC is 0.75%. The lowest concentration of Dettol and Clorox required to kill E. coli K12 (JM109) or MBC is at the concentration of 3.0% and 5.0%, respectively. Aganol showed less effective bacteriostatic and bactericidal agents, where it required higher MIC of 1.25% and MBC of 10%. The susceptibility test indicated that the Clorox is the most effective antibacterial agent with the minimum inhibition zone of 7 mm at a concentration of 1.75%. Higher concentrations of Dettol and Aganol (of 10% and 20%, respectively) are needed to exhibit the antibacterial activity with the minimum inhibition zone of 7 mm

    Assessing Indoor air quality and sick building syndrome in public University buildings: a cross-sectional study of office worker health and well-being

    Get PDF
    Exposure to indoor air pollution among office workers can result in various health issues and increase the incidence of Sick Building Syndrome (SBS). The aim of the present study was to investigate the effect of exposure to Indoor Air Quality (IAQ) among office workers and the relationship with the prevalence of SBS at Universiti Kebangsaan Malaysia (UKM), Bangi. A cross-sectional comparison research involving 144 office workers from various new and old buildings was carried out at UKM, Bangi. Information was gathered and symptoms associated with SBS were determined using a series of questionnaires. During office hours, IAQ parameters were collected using air quality sensor. The old building had substantially higher levels of NO2 (24.26 ppb), CO (0.62 ppb), and PM10 (4.99 μg/m3) than the new building. It was found that, with a p < 0.001, the concentration of O3 in the new building (11.47 ppb) was significantly higher than in the old building (4.93 ppb). The study’s findings also showed that the difference in temperature between the old buildings (26°C) and new buildings (24°C) was statistically significant (p = 0.003). Referring to relative humidity (RH), the result of the old building is lower (56%) compared to the new building (62%). Although old buildings exhibited a higher prevalence of SBS (34.7%), it was found that there was no significant difference compared to new buildings (27.5%). According to the study’s findings, found that exposure to CO (χ2 = 5.242, p = 0.022), PM10 (χ2 = 13.449, p < 0.001), and PM2.5 (χ2 = 19.755, p < 0.001) among office workers with the prevalence of SBS has significant association. In conclusion, this study suggests that exposure to high levels of CO, PM10 and PM2.5 can increase the prevalence of SBS. Good housekeeping and regular maintenance of ventilation can keep good IAQ and reduce health effects among occupants

    Assessing the effect of airport physical environment on passenger's satisfaction: a mediating effect of passenger's delight / Nur Aida Amani Baharuddin and Mazlina Mahdzar.

    No full text
    In tourism development, the impact of demand for air transport by travelers is affecting new forms of tourism and new destinations. The airport is a consistent growth segment in the tourism industry and transportation. The objective of the proposed study is to investigate the influence of physical environment of the airport on passengers’ delight and satisfaction. Studies on the physical environment impact on customer delight and satisfaction are still limited, especially in the context of international airports. In order to understand this phenomenon, the study examines the literature, raises issues and develops the framework within the research context. The study will opt a convenience sampling method, with a total of 400 sets of questionnaires will be distributed to local and international passengers at Kota Kinabalu International Airports (KKIA). This study provides theoretical basis for future research on the role of physical environment of international airports and its impact on passengers’ emotions and behavior. It also assists international airport industry practitioners to better understand how airport physical environments affects passengers’ experience and satisfaction

    Molecular Docking Studies of Selected Medicinal Drugs as Dengue Virus-2 Protease Inhibitors

    No full text
    Dengue is a potentially deadly disease with no effective drug. An in silico molecular docking was performed using Autodock 4.2.6 to investigate the molecular interactions between protease inhibitors, comprising antibiotic derivatives namely doxycycline (3), rolitetracycline (5) and a non-steroidal anti-inflammatory drug (NSAID), meclofenamic acid (4), against the NS2B-NS3 protease from dengue virus-2 (DENV-2). The non-competitive inhibitor (3) showed lower binding energy (-5.15 kcal/mol) than the predicted competitive inhibitors 4 and 5 (-3.64 and -3.21 kcal/mol, respectively). Structural analyses showed compound 3 that bound to a specific allosteric site, interacted with Lys74, a significant amino acid residue bonded to one of the catalytic triad, Asp75. Compounds 4 and 5 showed direct binding with two of the catalytic triad, His51 and Ser135, hence, predicted to be competitive inhibitors

    Presence of Residual Oil in Relation to Solid Particle Distribution in Palm Oil Mill Effluent

    No full text
    The production of palm oil requires a large amount of water, which subsequently turns into wastewater known as palm oil mill effluent (POME). Because of its high organic content, there has been debate over how to utilize POME for oil recovery. POME is usually mainly comprised of water (95 to 96%), total solids (4 to 5%), suspended solids (2 to 4%), and oil (0.6 to 0.7%). The lignocellulosic particles in POME are highly oleophilic and capable of absorbing oil. Therefore, the objective of this study was to understand the presence of residual oil and try to relate with the oil loss in POME and to identify the solid particles in POME and their correlations. Microscopic observations showed that most of the oil droplets available in POME were less than 100 µm in size. If given the opportunity to settle, the highest quantity of oil droplets and solid particles was in the bottom layer, followed by the middle layer, and lastly the upper layer. In cases where the contact angle of water was less than 45° on POME solids, the absorption rate was 0.11 ± 0.03 µL/s and 0.09 ± 0.01 µL/s, respectively. This study concluded that the oil losses in POME were partly due to the absorption of oil by the fibers

    Presence of Residual Oil in Relation to Solid Particle Distribution in Palm Oil Mill Effluent

    Get PDF
    The production of palm oil requires a large amount of water, which subsequently turns into wastewater known as palm oil mill effluent (POME). Because of its high organic content, there has been debate over how to utilize POME for oil recovery. POME is usually mainly comprised of water (95 to 96%), total solids (4 to 5%), suspended solids (2 to 4%), and oil (0.6 to 0.7%). The lignocellulosic particles in POME are highly oleophilic and capable of absorbing oil. Therefore, the objective of this study was to understand the presence of residual oil and try to relate with the oil loss in POME and to identify the solid particles in POME and their correlations. Microscopic observations showed that most of the oil droplets available in POME were less than 100 µm in size. If given the opportunity to settle, the highest quantity of oil droplets and solid particles was in the bottom layer, followed by the middle layer, and lastly the upper layer. In cases where the contact angle of water was less than 45° on POME solids, the absorption rate was 0.11 ± 0.03 µL/s and 0.09 ± 0.01 µL/s, respectively. This study concluded that the oil losses in POME were partly due to the absorption of oil by the fibers
    corecore