Universal behavior of localization of residue fluctuations in globular proteins

Localization properties of residue fluctuations in globular proteins are studied theoretically by using the Gaussian network model. Participation ratio for each residue fluctuation mode is calculated. It is found that the relationship between participation ratio and frequency is similar for all globular proteins, indicating a universal behavior in spite of their different size, shape, and architecture.Comment: 4 pages, 3 figures. To appear in Phys. Rev.

Dampak Bangkitan Lalu-Lintas Kawasan Ekonomi Khusus (KEK) Palu Terhadap Kinerja Perkerasan Jalan (Studi kasus Ruas Jalan Nasional Pantoloan-Tawaeli)

Palu City is designated as a Special Economic Zone for the development of the region's economic potential, as an integrated logistics center and mining processing industry in the Sulawesi economic corridor to encourage equity and increase and accelerate the economy. The performance of road pavements will decrease as the road service ages. The impact of the existence of Palu Special Economic zone resulted in the rise/pull of new traffic movements that burdened the National Pantoloan-Tawaeli road section, This research was conducted under the guidance of Pavement Design Manual 2017, where from the results of the research there was traffic loading due to the existence of the Palu Special Economic Zone amounted to 997, 761, 256 CESAL, resulting in a reduction in the life of road services by 10 years

Hubungan Kualitas Pelayanan, Kepuasan Dan Loyalitas Pengguna Ojek Sepedamotor

Perceived service quality and satisfaction by users is important aspects on service decision making of travel mode choice. Ojek motorcycle (MC) is an informal public transport recently tends to increase used for short distance in Indonesia cities. This study aim to investigate effect and the relationships of service quality, satisfaction and loyalty of USAge of ojek's MC. the study employs a questionnaire survey and home interviews for ojek's MC users in Bandung City. The analysis is conducted by using structural equation modeling (SEM). The study's results are as follows: from second order confirmatory factor analysis, it's found that time reliability and accessibility factors are significant reflection of service quality, but environment factor is not significant. From analysis the structural relationships between latent variables, it is found that service quality influence directly and significantly to satisfaction and then affect loyalty. Finally, it concludes that the ojek's MC is still popularity used for urban passenger's public transport, especially for short distance in Indonesia citie

TINJAUAN YURIDIS TERHADAP TINDAK PIDANA KELALAIAN YANG MENYEBABKAN KEMATIAN (STUDI KASUS PADA PUTUSAN NO. 52 / PID.B / 2012 / PN. BR)

2014Bahar T, B111 08 352, TINJAUAN YURIDIS TERHADAP \ud TINDAKPIDANA KELALAIAN YANG MENYEBABKAN KEMATIAN \ud (STUDIKASUS PADA PUTUSAN NO. 52 / PID.B / 2012 / PN. BR), di bawah \ud bimbingan M. SAID KARIM selaku pembimbing I dan AMIR ILYAS selaku \ud pembimbing II. \ud Penelitian ini bertujuan untuk mengetahui bagaimana penerapan hukum \ud terhadap delik kelalaian dan apa pertimbangan hakim dalam menjatuhkan \ud putusan delik kelalaian yang menyebabkan kematian. \ud Penelitian ini dilaksanakan di Kabupaten Barru dengan memilih instansi yang \ud terkait dengan perkara ini yaitu dilaksanakan di Pengadilan Negeri Barru. \ud Metode pengumpulan data yang digunakan adalah Metode Kepustakaan dan \ud Metode Wawancara kemudian data yang diperoleh dianalisis secara kualitatif. \ud Hasil penelitian menunjukkan bahwa (1). Penerapan hukum pidana \ud terhadap delik kelalaian yang menyebabkan kematian. ketentuan pidana pada \ud perkara ini yakni Pasal 359 Jo. Pasal 55 ayat (1) ke-1 telah sesuai dengan fakta-fakta hukum baik keterangan para saksi, keterangan ahli, dan keterangan \ud terdakwa dan terdakwa dianggap sehat jasmani dan rohani, tidak terdapat \ud gangguan mental sehingga dianggap mampu mempertanggungjawabkan \ud perbuatannya. (2). Pertimbangan hakim dalam memustukan perkara putusan \ud Nomor : 52/Pid.B/2012/PN.BR telah sesuai karena berdasarkan penjabaran \ud keterangan para saksi, keterangan terdakwa, dan alat bukti serta adanya \ud pertimbangan-pertimbangan yuridis, hal-hal yang meringankan dan \ud memberatkan, serta di perkuat dengan keyakinan hakim

PENGARUH PENAMBAHAN CAROTENE BUTTER DAN SUBTITUSI TAPE SINGKONG TERHADAP SIFAT ORGANOLEPTIK KUE ADEE

Kue Adee adalah kue khas Aceh khususnya daerah Pidie Jaya yang terbuat dari singkong atau tepung terigu. Penelitian ini bertujuan untuk mengetahui : 1) Pengaruh jumlah subtitusi tape singkong dan penambahan Carotene butter  terhadap sifat organoleptik kue adee; 2)Respon panelis terhadap produk kue Adee yang telah disubtitusi tape singkong dan penambahan carotene butter; 3) Formula kue Adee terbaik; 4) Kandungan gizi Kue Adee meliputi karbohidrat, lemak, protein, kandungan air, abu dan β-Karoten. Dan manfaat penelitian ini adalah meningkatkan mutu izi kue Adee dan membuat kue Adee dapat dipasarkan lebih luas. Penelitian ini menggunakan dua (2) variabel bebas dalam eksperimen dengan jumlah subtitusi tape yang terdiri dari tiga level yaitu 20gr, 30gr dan 40gr serta jumlah penambahan carotene butter sebanyak 15gr dan 30gr. Data yang dikumpulkan adalah data primer berupa sifat organoleptik kue produk (warna, aroma, kepadatan, rasa, dan tingkat kesukaan). Pengambilan data dilakukan dengan lembar uji organoleptik yang dibagikan kepadapanelis berjumlah 35 orang. Hasil data diolah menggunakan metode Kruskall – Wallis dan uji Mann-Whitney jika ada perbedaan yang signifikan antara produk dan menggunakan uji De Garmo untuk menentukan produk terbaik dan diuji kandungan giziny

Pembinaan Karakter Anak pada Sekolah Alam Insan Kamil di Kelurahan Tamarungan Kecamatan Somba Opu Kabupaten Gowa

Pokok masalah penelitian ini adalah bagaimana pembinaan karakter anak pada Sekolah Alam Insan Kamil di Kelurahan Tamarunang Kecamatan Somba Opu Kabupaten Gowa? Pokok masalah tersebut selanjutnya diuraikan ke dalam beberapa submasalah, yaitu: 1) Bagaimana metode pembinaan karakter anak pada Sekolah Alam Insan Kamil?, 2) Bagaimana manfaat pembinaan karakter anak pada Sekolah Alam Insan Kamil?, dan 3) Apa faktor pendukung dan penghambat pembinaan karakter anak pada Sekolah Alam Insan Kamil? Jenis penelitian ini tergolong kualitatif dengan pendekatan penelitian yang digunakan adalah: pendekatan sosiologis dan pendekatan psikologi. Adapun sumber data penelitian ini adalah data primer dan data sekunder. Data primer dari Ketua Yayasan Qalbu, Direktur Pendidikan SAIK, Kepala SAIK, para pembina serta orang tua anak. Adapun data sekunder dari pengamatan anak didik SAIK, buku, artikel serta penelusuran referensi yang ada relevansinya dengan penelitian. Metode pengumpulan data yang digunakan adalah observasi dan wawancara. Teknik pengolahan dan analisis data dilakukan dengan melalui tiga tahapan, yaitu: reduksi data, penyajian data dan penarikan kesimpulan. Hasil penelitian ini menunjukkan bahwa terdapat lima metode pembinaan karakter anak yang diterapkan di Sekolah Alam Insan Kamil, yaitu: pengembangan akhlak melalui metode teladan, pengembangan kreatifitas melalui kegiatan learning by games, pengembangan logika dan daya cipta melalui expreriental learning, pengembangan kepemimpinan melalui metode outbound dan pengembangan karakter mandiri melalui entrepreneurship games. Guna mengatasi faktor penghambat, pengurus SAIK memberikan pelatihan khusus kepada para pembina untuk meningkatkan kemampuan dan kompetensi pembina sebagai tenaga pendidik termasuk dalam hal melakukan pembinaan karakter pada anak serta mengadakan pertemuan Forum Silaturahim (FORSIL) bulanan dengan tujuan agar pembina dan orang tua bersinergi dalam hal perkembangan anak. Implikasi dari penelitian ini adalah agar pengurus SAIK lebih memperhatikan lagi kekurangan yang terdapat dalam lingkup SAIK terutama dari pembinanya, fasilitas sekolah alam yang perlu dilengkapi dan kerjasama sinergis antara orang tua, sekolah, masyarakat dan pengambil kebijakan perlu digalakkan dalam rangka keberhasilan pembinaan karakter

HUBUNGAN ANTARA PENGETAHUAN DAN SIKAP DENGAN TINDAKAN PENGGUNAN ALAT PELINDUNG DIRI PADA PEKERJA CLEANING SERVICE DI RSUP PROF. DR.R.D. KANDOU MANADO

Kesehatan dan keselamatan kerja suatu pemikiran dan upaya yang bertujuan untuk menjamin kesempurnaan serta keutuhan jasmani maupun  rohani dan diharapkan pekerja dapat melaksanakan setiap pekerjaannya dengan kondisi yang aman dan nyaman. Pekerjaan yang aman yaitu jika apapun yang dilakukan pekerja tersebut terhindar dari resiko bahaya di tempat kerja. Pekerjaan dikategorikan nyaman jika dalam melakukan pekerjaanya, setiap pekerja dapat merasa nyaman dan betah sehingga pekerja menjadi tidak mudah capek. Penelitian ini bertujuan untuk mengetahui hubungan antara pengetahuan dan sikap dengan tindakan penggunaan Alat Pelindung Diri (APD) pada pekerja pada pekerja cleaning service di RSUP Prof. Dr.R.D. Kandou Manado. Penelitian ini menggunakan pendekatan cross-sectional. Pengambilan sampel dilakukan dengan metode Simple Random Sampling yaitu dengan mengundi sampel sehingga dari total populasi yaitu 147, diambil 107 yang menjadi sampel penelitian. Kuisioner digunakan dalam pengukuran tingkat pengetahuan, sikap dengan tindakan penggunaan APD.Dengan menggunakan uji chi square didapatlah hasil yaitu terdapat hubungan antara pengetahuan dengan tindakan penggunaan alat pelindung diri dengan nilai p=0,042, serta terdapat hubungan antara sikap dengan tindakan penggunaan alat pelindung diri dengan nilai p=0,018. Kesimpulan dari penelitian ini yaitu terdapat hubungan antara pengetahuan dengan tindakan penggunaan APD, dan terdapat hubungan antara sikap dengan tindakan penggunaan APD pada pekerja cleaning service di RSUP.Prof.Dr.R.D.Kandou.Manado  Kata Kunci : Pengetahuan, Sikap, Tindakan, Alat Pelindung Diri   ABSTRACT Occupational health and safety a thought and effort that aims to guarantee perfection and wholeness of physical as well as spiritual and expected workers can carry out his job with any condition that is safe and comfortable. A secure job that is if any of these workers is done to avoid the risk of danger in the workplace. Jobs categorized inconvenient if in doing improvements, each worker can feel comfortable and at home so that workers be not easily tired. This research aims to know the relationship between knowledge and attitudes with the use of Peraonl Protective Equipment (PPE) on workers at the workers in the cleaning service was Prof. Dr. R.D. Kandou Manado. This research uses a cross-sectional approach. Sampling done by the method of Simple Random Sampling is to draw a sample so that the total population of 147, i.e. taken 107 who became the research sample. Questionnaire used in the measurement of the level of knowledge, attitudes with use of the PPE actions. By using test chi square didapatlah results i.e. There is a relationship between knowledge with the use of protective actions themselves with value p = 0.042, and there is a relationship between attitudes with the use of protective actions themselves with the value of 0,018 p =. The conclusions of the study i.e. There is a relationship between the use of PERSONAL knowledge with action, and there is a relationship between attitudes with use of the PPE actions on a worker cleaning service in was. Prof. Dr. R.D. Kandou. Manado  Keywords: Knowledge, Attitude, Act, Personal Protective Equipment

Reward-Related Neural Activity and Adolescent Antisocial Behavior in a Community Sample

Behavioral research has found evidence supporting reward dominance in adolescence with externalizing disorders, but findings from neuroimaging studies have been largely heterogeneous. We examined the Feedback-Related Negativity (FRN) and P3b in relation to self-reported externalizing behavior among 78 adolescents (11-18 yrs) during a monetary gambling task with concurrent high-density electroencephalogram. As expected, the P3b and the FRN demonstrated greater evoked activity to reward and punishment, respectively. Further, high externalizing behavior was associated with greater P3b difference and reduced FRN difference in response to reward and punishment, suggesting that externalizing behaviors may be associated with both reward dominance and reduced feedback-monitoring

Oscillatory delta and theta frequencies differentially support multiple items encoding to optimize memory performance during the digit span task

The human brain has limited storage capacity often challenging the encoding and recall of a long series of multiple items. Different encoding strategies are therefore employed to optimize performance in memory processes such as chunking where particular items are ‘grouped’ to reduce the number of items to store artificially. Additionally, related to the position of an item within a series, there is a tendency to remember the first and last items on the list better than the middle ones, which calls the “serial position effect”. Although relatively well-established in behavioral research, the neuronal mechanisms underlying such encoding strategies and memory effects remain poorly understood. Here, we used event-related EEG oscillation analyses to unravel the neuronal substrates of serial encoding strategies and effects during the behaviorally controlled execution of the digit span task. We recorded EEG in forty-four healthy young-adult participants during a backward digit span (ds) task with two difficulty levels (i.e., 3-ds and 5-ds). Participants were asked to recall the digits in reverse order after the presentation of each set. We analyzed the pattern of event-related delta and theta oscillatory power in the time-frequency domain over fronto-central and parieto-occipital areas during the item (digit) list encoding, focusing on how these oscillatory responses changed with each subsequent digit being encoded in the series. Results showed that the development of event-related delta power evoked by digits in each series matched the ‘serial position curve’, with higher delta power being present during the first, and especially last, digits as compared to digits presented in the middle of a set, for both difficulty levels. Event-related theta power, in contrast, rather resembled a neural correlate of a chunking pattern where, during the 5-ds encoding, a clear change in event-related theta occurred around the third/fourth positions, with decreasing power values for later digits. This suggests that different oscillatory mechanisms linked to different frequency bands may code for the different encoding strategies and effects in serial item presentation. Furthermore, recall-EEG correlations suggested that participants with higher fronto-central delta responses during digit encoding showed also higher recall scores. The here presented findings contribute to our understanding of the neural oscillatory mechanisms underlying multiple item encoding, directly informing recent efforts towards memory enhancement through targeted oscillation-based neuromodulation.Türkiye Bilimsel ve Teknolojik Araştırma Kurum

Statistical Properties of Contact Maps

A contact map is a simple representation of the structure of proteins and other chain-like macromolecules. This representation is quite amenable to numerical studies of folding. We show that the number of contact maps corresponding to the possible configurations of a polypeptide chain of N amino acids, represented by (N-1)-step self avoiding walks on a lattice, grows exponentially with N for all dimensions D>1. We carry out exact enumerations in D=2 on the square and triangular lattices for walks of up to 20 steps and investigate various statistical properties of contact maps corresponding to such walks. We also study the exact statistics of contact maps generated by walks on a ladder.Comment: Latex file, 15 pages, 12 eps figures. To appear on Phys. Rev.