550 research outputs found
State-of-the-art survey of dissimilar metal joining by solid state welding
State-of-the-art of dissimilar metal joining by solid state diffusion bonding and roll and press welding, emphasizing stainless steel and aluminum allo
Estimating the Collapse Pressure of an Inflatable Aerodynamic Decelerator
The collapse pressure of an inflatable membrane is the minimum differential pressure which will sustain a specific desired shape under an applied load. In this paper, we present a method for estimating the collapse pressure of a tension-cone inflatable aerodynamic decelerator (IAD) that is subject to a static aerodynamic load. The IAD surface is modeled as an elastic membrane. For a given aerodynamic load and sufficiently high torus differential pressure, the IAD assumes a stable axisymmetric equilibrium shape. When the torus pressure is reduced sufficiently, the symmetric equilibrium state becomes unstable and we define this instance to be the critical pressure Pcr. In this paper, we will compare our predicted critical torus pressure with the corresponding observed torus collapse pressure (OTCP) for fifteen tests that were conducted by the third author and his collaborators at the NASA Glenn Research Center 10x10 Supersonic Wind Tunnel in April 2008. One of the difficulties with these types of comparisons is establishing the instance of torus collapse and determining the OTCP from quantities measured during the experiment. In many cases, torus collapse is gradual and the OTCP is not well-defined. However, in eight of the fifteen wind tunnel tests where the OTCP is well-defined, we find that the average of the relative differences (Pcr - OTCP/Pcr) was 8.9%. For completeness, we will also discuss the seven tests where the observed torus collapse pressure is not well-defined
Isolation of native plasma membrane H<sup>+</sup>-ATPase (Pma1p) in both the active and basal activation states
The yeast plasma membrane H(+)-ATPase Pma1p is a P-type ATPase that energizes the yeast plasma membrane. Pma1p exists in two activation states: an autoinhibited basal state and an activated state. Here we show that functional and stable Pma1p can be purified in native form and reconstituted in artificial liposomes without altering its activation state. Acetylated tubulin has previously been reported to maintain Pma1p in the basal state but, as this protein was absent from the purified preparations, it cannot be an essential component of the autoinhibitory mechanism. Purification of and reconstitution of native Pma1p in both activation states opens up for a direct comparison of the transport properties of these states, which allowed us to confirm that the basal state has a low coupling ratio between ATP hydrolysis and protons pumped, whereas the activated state has a high coupling ratio. The ability to prepare native Pma1p in both activation states will facilitate further structural and biochemical studies examining the mechanism by which plasma membrane H(+)-ATPases are autoinhibited
The anatomical landmarks effective in the localisation of the median nerve during orthopaedic procedures
Background: The aim of this study was to create a safe zone for surgeons who perform procedures in the wrist to avoid iatrogenic damage to the median nerve (MN) by identifying anatomical landmarks using ultrasound (USG).Materials and methods: We measured the distances between the MN and two easily identifiable anatomical landmarks at the level of the proximal border of carpal ligament using USG.Results: A total of 57 volunteers (n = 114 upper limbs) were included in this study. Our main findings revealed that the distance from the flexor carpi radialis tendon to MN (FCR-MN) was 7.87 mm (95% confidence interval 7.37–8.37) and the distance from flexor carpi ulnaris tendon to MN (FCU-MN) was 19.09 mm (95% confidence interval 18.51–19.67).Conclusions: The tendons of FCR and FCU are easily identifiable landmarks that can be distinguished using simple palpation. Based on our USG findings, the area around FCR should be carefully navigated to avoid iatrogenic injury to the MN during surgical procedures around the carpal tunnel
The Nylon Scintillator Containment Vessels for the Borexino Solar Neutrino Experiment
Borexino is a solar neutrino experiment designed to observe the 0.86 MeV Be-7
neutrinos emitted in the pp cycle of the sun. Neutrinos will be detected by
their elastic scattering on electrons in 100 tons of liquid scintillator. The
neutrino event rate in the scintillator is expected to be low (~0.35 events per
day per ton), and the signals will be at energies below 1.5 MeV, where
background from natural radioactivity is prominent. Scintillation light
produced by the recoil electrons is observed by an array of 2240
photomultiplier tubes. Because of the intrinsic radioactive contaminants in
these PMTs, the liquid scintillator is shielded from them by a thick barrier of
buffer fluid. A spherical vessel made of thin nylon film contains the
scintillator, separating it from the surrounding buffer. The buffer region
itself is divided into two concentric shells by a second nylon vessel in order
to prevent inward diffusion of radon atoms. The radioactive background
requirements for Borexino are challenging to meet, especially for the
scintillator and these nylon vessels. Besides meeting requirements for low
radioactivity, the nylon vessels must also satisfy requirements for mechanical,
optical, and chemical properties. The present paper describes the research and
development, construction, and installation of the nylon vessels for the
Borexino experiment
A Comprehensive Approach to Improving U.S. Security Force Assistance Efforts
Security Force Assistance is analyzed, and some specific recommendations designed to improve U.S. performance are provided. While SFA may be a new term, the activities themselves are familiar ones related to how the Department of Defense works to train, advise, and assist foreign partners\u27 security establishments to accomplish common objectives. The United States has demonstrated serious SFA deficiencies in recent years. As Secretary of Defense Robert Gates has noted, the United States is likely to remain actively and broadly engaged in SFA for many years to come. The need for comprehensive improvement encompasses DoD military and civilian efforts and requires thoughtful integration with broader whole of government approaches.https://press.armywarcollege.edu/monographs/1353/thumbnail.jp
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Spatial And Quantitative Approache to Incorporating Stakeholder Values into Total Maximum Daily Loads: Dominguez Channel Case Study Final Report
Under the Federal Clean Water Act (CWA) states are required to develop and implement Total Maximum Daily Loads (TMDLs) for waters that are not achieving water quality standards. A TMDL specifies the maximum amount of a pollutant that a water body can receive, and allocates the pollutant loadings to point and non-point sources. Lawrence Livermore National Laboratory (LLNL) developed a tool to assist in improving the TMDL process. We developed a stakeholder allocation model (SAM) which uses multi-attribute utility theory to quantitatively structure the preferences of the major stakeholder groups. We then applied a Geographic Information System (GIS) to visualize the results. We used the Dominguez Channel Watershed in Los Angeles County, CA as our case study
An anatomical investigation of rare upper limb neuropathies due to the Struthers’ ligament or arcade: a meta-analysis
Background: The Struthers’ ligament (SL) is a fibrous band that originates fromthe supracondylar humeral process and inserts into the medial humeral epicondyle, potentially compressing both the median nerve and brachial artery. The controversial Struthers’ arcade (SA) is a musculotendinous band found in the distal end of the arm that might compress the ulnar nerve. This study aimed to evaluate the pooled prevalence estimate of the SL and SA, and their anatomical features. Materials and methods: A meticulous search of major electronic medical databases was carried out regarding both structures. Applicable articles (and all relevant references) were analysed. Data from the eligible articles was extracted and evaluated. The quality and the potential risk of bias in the included studies were assessed using the AQUA tool. Results: The arcade was reported in 13 studies (510 arms), whereas the ligament in 6 studies (513 arms). The overall pooled prevalence estimate of the ligament was 1.8%, and 52.6% for the arcade. Most frequently, the ulnar nerve was covered by a tendinous arcade (42.2%). In all cases, the ligament inserted into the medial humeral epicondyle, but had various origins. Only 1 study reported compression of the median nerve by the ligament, whilst another contradicted this view. Conclusions: Although the SL is rare, and the SA is a valid anatomical entity (though with a variable presentation), clinically meaningful neurovascular entrapments caused by these structures are infrequent. Nonetheless, a better understanding of each may be beneficial for the best patient outcomes
Clefting in a Pumpkin Balloon
NASA\u27s development of a large payload, high altitude, long duration balloon, the Ultra Long Duration Balloon, centers on a pumpkin shape super-pressure design. Under certain circumstances, it has been observed that a pumpkin balloon may be unable to pressurize into the desired cyclically symmetric equilibrium configuration, settling into a distorted, undesired state instead. In this paper, we will use th concept of stability to classify equilibrium shapes of fully pressurized/fully deployed strained ball oons
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Spatial and Quantitative Approach to Incorporating Stakeholder Values into Total Maximum Daily Loads: Dominguez Channel Case Study
The Federal Clean Water Act (CWA) Section 303(d)(1)(A) requires each state to identify those waters that are not achieving water quality standards. The result of this assessment is called the 303(d) list. The CWA also requires states to develop and implement Total Maximum Daily Loads (TMDLs) for these waters on the 303(d) list. A TMDL specifies the maximum amount of a pollutant that a water body can receive and still meet water quality standards, and allocates the pollutant loadings to point and non-point sources. Nationwide, over 34,900 segments of waterways have been listed as impaired by the Environmental Protection Agency (EPA 2006). The EPA enlists state agencies and local communities to submit TMDL plans to reduce discharges by specified dates or have them developed by the EPA. The Department of Energy requested Lawrence Livermore National Laboratory (LLNL) to develop appropriate tools to assist in improving the TMDL process. An investigation of this process by LLNL found that plans to reduce discharges were being developed based on a wide range of site investigation methods. Our investigation found that given the resources available to the interested and responsible parties, developing a quantitative stakeholder input process and using visualization tools to display quantitative information could improve the acceptability of TMDL plans. We developed a stakeholder allocation model (SAM) which uses multi-attribute utility theory to quantitatively structure the preferences of the major stakeholder groups. We then applied GIS to display allocation options in maps representing economic activity, community groups, and city agencies. This allows allocation options and stakeholder concerns to be represented in both space and time. The primary goal of this tool is to provide a quantitative and visual display of stakeholder concerns over possible TMDL options
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