63 research outputs found

    Early Detection, Diagnosis and Intervention Services for Young Children with Autism Spectrum Disorder in the European Union (ASDEU): Family and Professional Perspectives

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    Early services for ASD need to canvas the opinions of both parents and professionals. These opinions are seldom compared in the same research study. This study aims to ascertain the views of families and professionals on early detection, diagnosis and intervention services for young children with ASD. An online survey compiled and analysed data from 2032 respondents across 14 European countries (60.9% were parents; 39.1% professionals). Using an ordinal scale from 1 to 7, parents’ opinions were more negative (mean = 4.6; SD 2.2) compared to those of professionals (mean = 4.9; SD 1.5) when reporting satisfaction with services. The results suggest services should take into account child’s age, delays in accessing services, and active stakeholders’ participation when looking to improve services

    Interspecific introgression mediates adaptation to whole genome duplication

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    Adaptive gene flow is a consequential phenomenon across all kingdoms. While recognition is increasing, examples lack of bidirectional gene flow mediating adaptations at loci that manage core processes. We previously discovered concerted molecular changes among interacting members of meiotic machinery controlling crossover number upon adaptation to whole genome duplication (WGD) in Arabidopsis arenosa. Here we conduct a population genomic study to test the hypothesis that adaptation to WGD has been mediated by adaptive gene flow between A. arenosa and A. lyrata. We find that A. lyrata underwent WGD more recently than A. arenosa, suggesting that pre-adapted alleles have rescued nascent A. lyrata, but we also detect gene flow in the opposite direction at functionally interacting loci under the most extreme levels of selection. These data indicate that bidirectional gene flow allowed for survival after WGD and that the merger of these species is greater than the sum of their parts

    The Molecular Identification of Organic Compounds in the Atmosphere: State of the Art and Challenges

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    Biosurfactants on aerosols: a link between biogenic activity and cloud formation ?

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