3 research outputs found
Candida esophagitis: species distribution and risk factors for infection Esofagite por Candida: distribuição da espécie e fatores de risco para a infecção
Although Candida albicans is the main cause of fungal esophagitis, other species such as C. tropicalis, C. krusei and C. stellatoidea have also been implicated. Several studies have identified risk factors for C. albicans esophagitis. However, data for non-C. albicans species is still sparse. The aim of this study was to determine the etiology of Candida esophagitis in our medical centre over an 18-month period. Additionally, we aimed to investigate predisposing conditions for esophageal candidosis caused by different Candida species. A total of 21,248 upper gastroscopies were performed in Santa Casa Complexo Hospitalar between January 2005 and July 2006. The prevalence of Candida esophagitis was 0.74% (n = 158). C. albicans caused the vast majority of infections (96.2%), followed by C. tropicalis (2.5%), C. lusitaniae (0.6%) and C. glabrata (0.6%). There were 81 women (51.3%) and 77 men (48.7%). No case of mixed infection occurred. Concomitant oral candidosis was documented for 10.8% (n = 17). Most of cases (55.1%) involved outpatients. Around one fifth of patients in our cohort had no identifiable risk factors for esophageal candidosis (20.8%). Since nearly all infections were caused by C. albicans we were not able to determine risk factors for esophagitis caused by other Candida species.<br>Embora Candida albicans seja a principal causa de esofagite fĂșngica, outras espĂ©cies como C. tropicalis, C. krusei e C. stellatoidea tambĂ©m tĂȘm sido implicadas. O objetivo desse estudo foi descrever espĂ©cies causadoras de esofagite fĂșngica em nosso centro durante um perĂodo de 18 meses, alĂ©m de comparar condiçÔes predisponentes para candidose esofĂĄgica causadas por diferentes espĂ©cies de Candida. De janeiro de 2005 a julho de 2006, 21.248 endoscopias digestivas altas foram realizadas no Complexo Hospitalar Santa Casa (Porto Alegre, Brasil). A prevalĂȘncia de esofagite por Candida foi de 0,74% (n = 158). C. albicans foi a causadora da maioria das infecçÔes (96,2%), seguida por C. tropicalis (2,5%), C. lusitaniae (0,6%) e C. glabrata (0,6%). Candidose oral concomitante foi documentada em 10,8% (n = 17). Cerca de 21% dos pacientes nĂŁo teve qualquer fator de risco identificĂĄvel para candidose esofĂĄgica. Em função do pequeno nĂșmero de pacientes infectados por espĂ©cies nĂŁo-Candida albicans, nĂŁo foi possĂvel determinarmos fatores de risco para estas infecçÔes