Evaluation of the compost barn system of milk producers from cooperatives in the mission region / Avaliação do sistema de celeiro composto de produtores de leite de cooperativas da região de missão

This work classifies dairy farms that use Compost Barn (CB) as a confinement system for dairy cows in the Mission Region of Rio Grande do Sul / Brazil. The Support Center for the Development of Milk Products and Processes installed in the Technological Park of URI Santo Ângelo aims to provide support to companies and milk producers in the region covered by TecnoURI. It is presented in this article that the study of the evaluation of the Compost Barn (CB) system used by milk producers of cooperatives in the Missions region of Rio Grande do Sul, which presents itself as a promising alternative for the production of raw milk, bringing better quality and welfare for the animals present in this system. This research identifies structural and handling factors that interfere with the quality of composted packaging. The data were obtained on the spot, with measurements of facilities, observations of herds and collection of technical information on dairy farms. In addition to the consolidated variables related to the handling and quality of the packaging, it is reported that the frequency of agitation, resting area per animal, presence of mechanical ventilation in the barn, the type of material used to compose the bedding package and the local relative humidity are factors that influence the main bed variables of the Composto Barn system and can be key points for the success of the CB system in subtropical regions of Brazil. This article presents the results of the study of the evaluation and improvement of the compost barn system of milk-producing members of cooperatives in the Missions region of Rio Grande do Sul, aiming at decreasing the milk CCS, as well as the identification of the microorganisms that cause mastitis. The influence of management on the quality of the bed is evident, mainly regarding the frequency of turning, correct dimensioning of the bed area, and the presence of a ventilation system. However, the good functioning of the system depends to a large extent on the adopted daily managements, which still need to be studied for a better understanding of the composting process, a key factor for success in production

Rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART): Study protocol for a randomized controlled trial

Background: Acute respiratory distress syndrome (ARDS) is associated with high in-hospital mortality. Alveolar recruitment followed by ventilation at optimal titrated PEEP may reduce ventilator-induced lung injury and improve oxygenation in patients with ARDS, but the effects on mortality and other clinical outcomes remain unknown. This article reports the rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART). Methods/Design: ART is a pragmatic, multicenter, randomized (concealed), controlled trial, which aims to determine if maximum stepwise alveolar recruitment associated with PEEP titration is able to increase 28-day survival in patients with ARDS compared to conventional treatment (ARDSNet strategy). We will enroll adult patients with ARDS of less than 72 h duration. The intervention group will receive an alveolar recruitment maneuver, with stepwise increases of PEEP achieving 45 cmH(2)O and peak pressure of 60 cmH2O, followed by ventilation with optimal PEEP titrated according to the static compliance of the respiratory system. In the control group, mechanical ventilation will follow a conventional protocol (ARDSNet). In both groups, we will use controlled volume mode with low tidal volumes (4 to 6 mL/kg of predicted body weight) and targeting plateau pressure <= 30 cmH2O. The primary outcome is 28-day survival, and the secondary outcomes are: length of ICU stay; length of hospital stay; pneumothorax requiring chest tube during first 7 days; barotrauma during first 7 days; mechanical ventilation-free days from days 1 to 28; ICU, in-hospital, and 6-month survival. ART is an event-guided trial planned to last until 520 events (deaths within 28 days) are observed. These events allow detection of a hazard ratio of 0.75, with 90% power and two-tailed type I error of 5%. All analysis will follow the intention-to-treat principle. Discussion: If the ART strategy with maximum recruitment and PEEP titration improves 28-day survival, this will represent a notable advance to the care of ARDS patients. Conversely, if the ART strategy is similar or inferior to the current evidence-based strategy (ARDSNet), this should also change current practice as many institutions routinely employ recruitment maneuvers and set PEEP levels according to some titration method.Hospital do Coracao (HCor) as part of the Program 'Hospitais de Excelencia a Servico do SUS (PROADI-SUS)'Brazilian Ministry of Healt

Produção de trigo duplo propósito com diferentes doses de adubação nitrogenada em cobertura

Currently, the practice of Crop-Livestock Integration is stimulated as a way of increasing the generation of foreign exchange for Brazil. Integrated systems improve land use efficiency as well as preserve, recover and increment or soil fertility. The aim of this research was to evaluate how different doses of nitrogen fertilization can affect production and quality of dual purpose wheat submitted to grazing. The experimental designed was randomized block with five treatments (0, 75, 150, 225 and 300 Kg N ha-1, like ammonium nitrate) and four repetitions. The forage yield, the percentage crude protein (P=.0001) and acid detergent insoluble protein (P=.0054) had a linear increased because of the nitrogen addition doses. The crude protein percentage changed the estimate of all soluble carbohydrates (P=.0001) and non-fibrous carbohydrates (P=.0186), but did not influence the, nitrogen detergent fiber corrected with ash and proteins percentage contributing for content cell. The crops production (P=.0001) and the number of kernels per ear (P=.0001) showed significantly difference because of the nitrogen additions dose, increasing the number of fertile flowers. The nitrogen topdressing alters forage production, the chemical composition and the production of dual purpose wheat grains subjected to grazing.Atualmente, é estimulada a prática de Integração Lavoura-Pecuária (ILP) como forma de incrementar a geração de divisas para o Brasil. Os sistemas integrados melhoram a eficiência de uso da terra, bem como preservam, recuperam e/ou incrementam a fertilidade do solo. Objetivou-se avaliar a produção e a composição bromatológica de trigo duplo propósito (TDP) manejado sob pastejo com diferentes doses de nitrogênio em cobertura (DAN): 0, 75, 150, 225 e 300 Kg de N ha-1, sob a forma de nitrato de amônia. Utilizou-se delineamento experimental de blocos casualizados com quatro repetições. A produção de forragem e os teores de proteína bruta (P=0,001) e proteína insolúvel em detergente ácido aumentaram (P=0,0054) linearmente, em função das DAN. O teor de proteína bruta (P=0,0001) impactou sobre as estimativas de carboidratos totais e de carboidratos não fibrosos, mas não influenciou (P=0,0186) os teores de fibra em detergente neutro corrigidas para cinzas e proteínas contribuindo para manutenção dos teores de conteúdo celular. A produção de grãos P=(0,0001) e o número de grãos por espigas diferiram (P=0,0001), em função das DAN, aumentando o número de flores férteis. A adubação nitrogenada em cobertura altera a produção de forragem, a composição bromatológica e a produção de grãos de trigo duplo propósito submetido à pastejo

Rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART): Study protocol for a randomized controlled trial

Background: Acute respiratory distress syndrome (ARDS) is associated with high in-hospital mortality. Alveolar recruitment followed by ventilation at optimal titrated PEEP may reduce ventilator-induced lung injury and improve oxygenation in patients with ARDS, but the effects on mortality and other clinical outcomes remain unknown. This article reports the rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART). Methods/Design: ART is a pragmatic, multicenter, randomized (concealed), controlled trial, which aims to determine if maximum stepwise alveolar recruitment associated with PEEP titration is able to increase 28-day survival in patients with ARDS compared to conventional treatment (ARDSNet strategy). We will enroll adult patients with ARDS of less than 72 h duration. The intervention group will receive an alveolar recruitment maneuver, with stepwise increases of PEEP achieving 45 cmH(2)O and peak pressure of 60 cmH2O, followed by ventilation with optimal PEEP titrated according to the static compliance of the respiratory system. In the control group, mechanical ventilation will follow a conventional protocol (ARDSNet). In both groups, we will use controlled volume mode with low tidal volumes (4 to 6 mL/kg of predicted body weight) and targeting plateau pressure <= 30 cmH2O. The primary outcome is 28-day survival, and the secondary outcomes are: length of ICU stay; length of hospital stay; pneumothorax requiring chest tube during first 7 days; barotrauma during first 7 days; mechanical ventilation-free days from days 1 to 28; ICU, in-hospital, and 6-month survival. ART is an event-guided trial planned to last until 520 events (deaths within 28 days) are observed. These events allow detection of a hazard ratio of 0.75, with 90% power and two-tailed type I error of 5%. All analysis will follow the intention-to-treat principle. Discussion: If the ART strategy with maximum recruitment and PEEP titration improves 28-day survival, this will represent a notable advance to the care of ARDS patients. Conversely, if the ART strategy is similar or inferior to the current evidence-based strategy (ARDSNet), this should also change current practice as many institutions routinely employ recruitment maneuvers and set PEEP levels according to some titration method.13Hospital do Coracao (HCor) as part of the Program 'Hospitais de Excelencia a Servico do SUS (PROADI-SUS)'Brazilian Ministry of Healt