Asymptotic approximation of the band structure for tetrachiral metamaterials

Tetrachiral materials are characterized by a cellular microstructure made by a periodic pattern of stiff rings and flexible ligaments. Their mechanical behaviour can be described by a planar lattice of rigid massive bodies and elastic massless beams. Therefore, the periodic cell dynamics is governed by a monoatomic structural model, conveniently reduced to the only active degrees-of-freedom. The paper presents an explicit parametric description of the Floquet-Bloch spectrum (or band structure) governing the propagation of elastic waves through the tetrachiral material. By virtue of multiparametric perturbation techniques, an analytical asymptotic approximation is achieved for the dispersion surfaces in the Brillouin zone. Since different optimization strategies tend to fail in opening low-frequency band gaps in the material spectrum, this specific design purpose is commonly pursued by introducing interring inertial resonators. The paper demonstrates that multiparametric perturbation methods can efficiently deal with the consequent enlargement of the parameter space, necessary to describe the resulting inertial metamaterial. Indeed, paying due attention to the doubling of internal resonance conditions, an accurate parametric approximations of the enriched band structure can be achieved. From the applicative perspective, the research findings furnish suited analytical tools for the optimal design of pass and stop bands

Who Cares? Young Europeans’ attitudes towards the disclosure of personal identity data

In policy circles, there is increasing attention to the privacy and safety of young people\u27s personal identity data. Identity disclosure seems to be an integral part of young people\u27s lifestyles. Also, there is mixed evidence on the different attitudes regarding disclosure between young adults and more mature cohorts. The present research examines peoples’ practices in relation to various services (e.g. social networking, health). It gauges opinions, thoughts and motivations towards personal identity data management and covers policy preferences in relation to the protection of identity data. The study was conducted in seven EU Member States, covering four regional groups where attitudes to disclosure have been shown to differ. Two focus groups were run in each country; one with young people aged 15 to 25, the other involving adults (25 to 70 years old). Analysis is based on two complementary qualitative techniques, using textual analysis software. Content analysis was used to identify the main topics emerging from the groups’ interactions, while a ‘discriminate’ analysis was performed to obtain a deeper insight into discourses’ similarities and differences in relation to specific variables such as age and regions/countries. While this research does not aim to provide a comprehensive view of Europeans\u27 perceptions, it highlights significant differences, particularly between young people and adults and between the different countries (cultural differences). This study consequently has significant scientific and policy implications. The results will help shape a final questionnaire for a EU27 survey on the same subject. This work will help the European Commission direct the Information Society agenda in the years to come

A systematic review and meta-analysis on the prevalence of dementia in europe. estimates from the highest-quality studies adopting the dsm iv diagnostic criteria

BACKGROUND: Dementia, including Alzheimer's disease (AD), is one of the most burdensome medical conditions. Usually, the reviews that aim at calculating the prevalence of dementia include estimates from studies without assessing their methodological quality. Alzheimer's Disease International (ADI) proposed a score to assess the methodological quality of population-based studies aimed at estimating the prevalence of dementia. During the last three years, the European Commission has funded three projects (Eurodem, EuroCoDe, and ALCOVE) in order to estimate the prevalence of dementia in Europe. OBJECTIVE: The aim of this study was to perform a systematic review and meta-analysis of data on the prevalence of dementia in Europe derived from studies that included only subjects with a diagnosis of dementia according to the DSM IV criteria, and that had a high quality score according to ADI criteria. METHODS: We considered the studies selected by the two projects EuroCoDe (1993-2007) and Alcove (2008-2011), and we performed a new bibliographic search. For the systematic review, we only selected the subset of articles that included subjects with a diagnosis of dementia according to the DSM IV criteria. The studies were qualitatively assessed using the ADI tool. RESULTS: The meta-analysis considered 9 studies that were carried out in Europe between 1993 and 2018 including a total of 18,263 participants, of which 2,137 were diagnosed with dementia. The prevalence rate standardized for age and sex resulted 7.1%. DISCUSSION: This is the first systematic review on the prevalence of dementia in Europe considering only high-quality studies adopting the same diagnostic criteria (i.e., DSM IV)

Revealing the organic dye and mordant composition of Paracas textiles by a combined analytical approach

The object of this study is a wide selection of dyed cotton and camelid samples from an important collection of 2000-year-old Paracas textiles, now at the Museo Nacional de Arqueología, Antropología e Historia del Perú (MNAAHP; Lima; Peru) and at the National Museum of World Culture (NMWC; Gothenburg; Sweden). The threads, chosen as representative of the whole palette, were selected from eighteen different textiles. A combined spectroscopic and spectrometric analytical approach was selected to characterize the organic and inorganic composition of this wide set of samples. In particular, technical photography was used to gain a general overview of the samples, X-ray fluorescence (XRF) was employed for identifying the mordants and mapping the elemental distribution in the threads, while liquid chromatography coupled with diode array detector and with high-resolution mass spectrometry (HPLC–DAD, HPLC–HRMS) were used for characterizing organic dye composition. This study provides fundamental information on the mordants or other inorganic auxiliaries used in the dyeing processes, rarely investigated up to now, and to the varieties of vegetal sources employed in Paracas textiles. The widening of the Andean dyestuff database is highly important not only to acquire knowledge on Paracas culture, but also to ease the dye characterization of archaeological textiles from the Peruvian region and South American area in general.[Figure not available: see fulltext.]

A phase field approach for damage propagation in periodic microstructured materials

In the present work, the evolution of damage in periodic composite materials is investigated through a novel finite element-based multiscale computational approach. The proposed methodology is developed by means of the original combination of asymptotic homogenization with the phase field approach to nonlocal damage. This last is applied at the macroscale level on the equivalent homogeneous continuum, whose constitutive properties are obtained in closed form via a two-scale asymptotic homogenization scheme. The formulation considers different assumptions on the evolution of damage at the microscale (e.g., damage in the matrix and not in the inclusion/fiber), as well as the role played by the microstructural reinforcement, i.e. its volumetric content and shape. Numerical results show that the proposed formulation leads to an apparent tensile strength and a post-peak branch of unnotched and notched specimens dependent not only on the internal length scale of the phase field approach, as for homogeneous materials, but also on microstructural features. Down-scaling relations provide the full reconstruction of the microscopic fields at any point of the macroscopic model, as a simple post-processing operation

An estimate of attributable cases of alzheimer disease and vascular dementia due to modifiable risk factors. the impact of primary prevention in europe and in italy

Background: Up to 53.7% of all cases of dementia are assumed to be due to Alzheimer disease (AD), while 15.8% are considered to be due to vascular dementia (VaD). In Europe, about 3 million cases of AD could be due to 7 potentially modifiable risk factors: diabetes, midlife hypertension and/or obesity, physical inactivity, depression, smoking, and low educational level. Aims: To estimate the number of VaD cases in Europe and the number of AD and VaD cases in Italy attributable to these 7 potentially modifiable risk factors. Methods: Assuming the nonindependence of the 7 risk factors, the adjusted combined population attributable risk (PAR) was estimated for AD and VaD. Results: In Europe, adjusted combined PAR was 31.4% for AD and 37.8% for VaD. The total number of attributable cases was 3,033,000 for AD and 873,000 for VaD. In Italy, assuming a 20% reduction of the prevalence of each risk factor, adjusted combined PAR decreased from 45.2 to 38.9% for AD and from 53.1 to 46.6% for VaD, implying a 6.4 and 6.5% reduction in the prevalence of AD and VaD, respectively. Conclusion: A relevant reduction of AD and VaD cases in Europe and Italy could be obtained through primary prevention

Elution study of acrylic monomers from orthodontic materials using high performance liquid chromatography (HPLC)

Purpose: Main goal of the study was the identification and quantitative analysis of monomer elution from materials commonly used in fixed orthodontic therapy. Studies have shown severe health effects of monomers including cytotoxic, allergenic or mutagenic potential and endocrine changes. This in vitro study focusses primarily on five resins which are usually processed intraorally and remain in the oral cavity long-term. Methods: We tested the elution of monomers from specimens (7.5 mm x 1.5 mm) immersed in artificial saliva at body temperature (37 degrees C) for 30 min to 5 weeks. The used method is in accordance with DIN EN ISO 10993-13. The five tested materials were BrackFix (R) (Voco GmbH, Cuxhaven, Germany), Triad (R) Gel (DeguDent GmbH, Hanau, Germany), and Transbond (TM) XT, LR and Plus (3M Unitek, Monrovia, CA, USA). All aliquots were analyzed using high performance liquid chromatography (HPLC). Data were statistically analyzed. Results: All five analyzed materials eluted substances over a period of 5 weeks. Identified substances included bisphenol A (BPA), triethylene glycol dimethacrylate (TEGDMA) and urethane dimethacrylate (UDMA). BPA eluted from Transbond (TM) Plus, XT, LR and BrackFix (R). The cumulated mean values after 35 days ranged from 16.04 to 64.83 ppm, depending on the material. TEGDMA eluted with a mean of 688.61 ppm from Transbond (TM) LR. UDMA with a mean of 1682.00 ppm from Triad (R) Gel. For each material the highest concentrations of all these substances were found in the first elution period. Other substances that were not equivocally identified or of low concentration also eluted. Conclusion: Using the described method, it is possible to qualitatively and quantitatively determine the in vitro elution of monomers from orthodontic materials. The concentrations of the substances identified were below the current maximum recommended intake. However, a cumulative effect and low-dose effects should be considered for both patients and dental professionals, especially for young patients. Measures to reduce exposure patients and practitioners are suggested