Who is Responsible for the Child - Is Anyone Responsible?

That Old-maid Aunt irritates me! The concluding paragraph of her otherwise rather pretty and sweet story is my only provocation for writing. Mind you, I have never seen the lady in question, nor have I the remotest idea as to who she is. Frankly, I inquired concerning her so that I might better appreciate her philosophy. But even women editors at times realize the value of a confidence, expressed or implied * * * how dare I continue now

Impact of liquids with different densities

The collision of liquids of different densities is studied theoretically for the case of liquids having wedge-shaped configuration before the impact. Both liquids are assumed to be ideal and incompressible, and the velocity potential theory is used for the flow of each liquid. Surface tension and gravity effects are neglected. The problem is decomposed into two self-similar problems, one for each liquid. Across the interface between the liquids, continuity of the pressure and the normal component of the velocity is enforced through iteration. This determines the shape of the interface and other flow parameters. The integral hodograph method is employed to derive the solution consisting of analytical expressions for the complex-velocity potential, the complex-conjugate velocity, and the mapping function. They are all defined in the first quadrant of a parameter plane, in which the original boundary-value problem is reduced to a system of integro-differential equations in terms of the velocity magnitude and the velocity angle relative to the flow boundary. They are solved numerically using the method of successive approximations. The results are presented through streamlines, interface and free-surface shapes, the pressure and velocity distributions. Special attention is given to the structure of the splash jet rising as a result of the impact

Study of different mortars used for soaking pit recuperators

Effective utilisation of waste heat by the use of recuperators system has become more and more imperative due to the recent energy crisis. Although both the recuperator and regenerator are used to preheat air, the co•efficient of heat transfer is higher in the recup-erators than that of regenerators (2,5-6.0 as compared to 1.5- 3.5 Btuift2/hr/°F.)1. A recuperator Is a device whereby heat is continuously transferred from hot waste gases to combustion air and thus preheating it. In many modern soaking pits, batch or continuous type reheating furnaces, ceramic recuperators are used for achieving very high preheat temperature. The efficiency of the ceramic recuperative system depends upon the quality of the refra-ctory tube and the mortars used for jointing material

Differences in client and therapist views of the working alliance in drug treatment

Background - There is growing evidence that the therapeutic alliance is one of the most consistent predictors of retention and outcomes in drug treatment. Recent psychotherapy research has indicated that there is a lack of agreement between client, therapist and observer ratings of the therapeutic alliance; however, the clinical implications of this lack of consensus have not been explored. Aims - The aims of the study are to (1) explore the extent to which, in drug treatment, clients and counsellors agree in their perceptions of their alliance, and (2) investigate whether the degree of disagreement between clients and counsellors is related to retention in treatment. Methods - The study recruited 187 clients starting residential rehabilitation treatment for drug misuse in three UK services. Client and counsellor ratings of the therapeutic alliance (using the WAI-S) were obtained during weeks 1-12. Retention was in this study defined as remaining in treatment for at least 12 weeks. Results - Client and counsellor ratings of the alliance were only weakly related (correlations ranging from r = 0.07 to 0.42) and tended to become more dissimilar over the first 12 weeks in treatment. However, whether or not clients and counsellors agreed on the quality of their relationship did not influence whether clients were retained in treatment. Conclusions - The low consensus between client and counsellor views of the alliance found in this and other studies highlights the need for drug counsellors to attend closely to their clients' perceptions of the alliance and to seek regular feedback from clients regarding their feelings about their therapeutic relationship

Extraction of [18F]fluoride from [18O]water by a fast fibrous anion exchange resin

[18F]Fluoride for nucleophilic radiofluorination was recovered from target water by trapping on a fibrous anion exchange resin in the hydroxide form and subsequent displacement into wet methanolic K2CO3. Extraction into methanol facilitated rapid evaporation and resolubilization of the [18F]fluoride as an ion pair. The resin was first dried in situ and rehydrated with [18O]H2O to avoid isotopic dilution of the target water.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/28900/1/0000737.pd

Sviluppo di tecniche di simulazione eterogenea funzionale e numerica applicate all’ingegneria di sistemi aeronautici

Questo studio illustra l’impiego del ‘Model Based Systems Engineering’ (MBSE), in cui strumenti di modellazione funzionale si integrano con modelli numerici, da tempo impiegati in progettazione, per la realizzazione di sistemi complessi. E’ analizzato un sistema antighiaccio aeronautico, sviluppato nell’ambito del progetto ‘CRYSTAL’. L’obiettivo è stato raggiunto collegando il gestore di requisiti IBM DOORS®, IBM RHAPSODY®, che opera in ambiente SysML, e SIMULINK® o DYMOLA®. L’interoperabilità è stata garantita dallo standard di connessione Functional Mock–up Interface (FMI), che ha permesso di validare il processo realizzando la cosiddetta ‘simulazione eterogenea’ di modelli funzionali e numerici integrati

Routine production of 2-deoxy-2-[18F]fluoro--glucose by direct nucleophilic exchange on a quaternary 4-aminopyridinium resin

Resin-supported [18F]fluoride ion has been prepared and applied to a rapid, convenient synthesis of [18F]FDG. "No-carrier-added" [18F]fluoride ion is collected on a quaternary 4-(N, N-dialkylamino)-pyridinium functionalized polystyrene anion exchange resin directly from a [18O]water target, dried by rinsing with acetonitrile, and then reacted with 1,3,4,6-tetra-O-acetyl-2-O-trifluoromethanesulfonyl-[beta]--mannopyrannose. Acidic hydrolysis yields [18F]FDG in a synthesis time of 40 min with overall yields presently averaging above 50%.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/28859/1/0000694.pd

Client and therapist views of contextual factors related to termination from psychotherapy: A comparison between unilateral and mutual terminators

Contextual variables potentially influencing premature termination were examined. Clients (n = 83) and therapists (n = 35) provided parallel data on early working alliance, psychotherapy termination decision (unilateral vs. mutual), clients’ reasons for termination, and barriers to treatment participation. When clients unilaterally ended therapy, therapists were only partially aware of either the extent of clients’ perceived improvements or their dissatisfaction. When termination was mutually determined, there were no differences between client and therapist ratings of termination reasons. Although working alliance and barriers to treatment participation were rated as lower in the context of unilateral termination by clients and therapists, all clients rated the early alliance and barriers to treatment more highly than did therapists. Results have implications for understanding premature termination and suggest future research examining the utility of therapist feedback regarding contextual variables in terms of retaining clients in therapy

Designing a memorial place

The design and selection of a memorial stone and the site of the grave, both of which represent the deceased, can be a central issue for people bereaved by traffic accidents. This was revealed in an interview survey of recent Swedish roadside memorials and other memorial places. In this article we consider the design and selection of the memorial stone and gravesite as expressions of continuing care for the deceased and as a way to offer comfort to the bereaved. Materiality, representation and presence will be discussed as crucial parts of the link between the living and the dead. Communicative, spatial and physical values are important also in the professional's design of common public memorial places. Of specific interest for this text are two design practice-based terms, memory object and passage landscape, which may be used by landscape architects when designing memorial places, such as cemeteries and public monuments. Throughout this text, we argue that memorial places like these are capable of bridging the gap between the space of life and the space of death, as well as supporting the regeneration of present memories and the construction of future ones

Dimer formation and conformational flexibility ensure cytoplasmic stability and nuclear accumulation of Elk-1

The ETS (E26) protein Elk-1 serves as a paradigm for mitogen-responsive transcription factors. It is multiply phosphorylated by mitogen-activated protein kinases (MAPKs), which it recruits into pre-initiation complexes on target gene promoters. However, events preparatory to Elk-1 phosphorylation are less well understood. Here, we identify two novel, functional elements in Elk-1 that determine its stability and nuclear accumulation. One element corresponds to a dimerization interface in the ETS domain and the second is a cryptic degron adjacent to the serum response factor (SRF)-interaction domain that marks dimerization-defective Elk-1 for rapid degradation by the ubiquitin–proteasome system. Dimerization appears to be crucial for Elk-1 stability only in the cytoplasm, as latent Elk-1 accumulates in the nucleus and interacts dynamically with DNA as a monomer. These findings define a novel role for the ETS domain of Elk-1 and demonstrate that nuclear accumulation of Elk-1 involves conformational flexibility prior to its phosphorylation by MAPKs