Автоматизированная система контроля и управления процессом безмазутной растопки пылеугольного котла

Цель работы – на основании результатов экспериментального исследования закономерностей процессов зажигания и горения пылеугольного топлива разработать автоматизированную систему контроля и управления процессом растопки котельного агрегата и обосновать технико-экономическую эффективность безмазутной растопки парового котла. Также в процессе экспериментальных исследований были установлены минимальные значения температуры окружающей среды и времена задержки зажигания, при которых устойчиво воспламеняется высокореакционное твердое натуральное топливо.The purpose of this work is develop an automated control system for the process ignition of boiler unit based on the results of an experimental study of regularities of ignition and combustion of pulverized-coal fuels and to justify the technical and economic effectiveness the oil-free firing of a steam boiler. Also, in the course of experimental studies, the minimum values of ambient temperature and the ignition delay times were established, at which the high-reactive solid natural fuel was ignited

B cell/stromal cell crosstalk in health, disease, and treatment: Follicular lymphoma as a paradigm

International audienceStromal cells organize specific anatomic compartments within bone marrow (BM) and secondary lymphoid organs where they finely regulate the behavior of mature normal B cells. In particular, lymphoid stromal cells (LSCs) form a phenotypically heterogeneous compartment including various cell subsets variably supporting B-cell survival, activation, proliferation, and differentiation. In turn, activated B cells trigger in-depth remodeling of LSC networks within lymph nodes (LN) and BM. Follicular lymphoma (FL) is one of the best paradigms of a B-cell neoplasia depending on a specific tumor microenvironment (TME), including cancer-associated fibroblasts (CAFs) emerging from the reprogramming of LN LSCs or poorly characterized local BM precursors. FL-CAFs support directly malignant B-cell growth and orchestrate FL permissive cell niche by contributing, through a bidirectional crosstalk, to the recruitment and polarization of immune TME subsets. Recent studies have highlighted a previously unexpected level of heterogeneity of both FL B cells and FL TME, underlined by FL-CAF plasticity. A better understanding of the signaling pathways, molecular mechanisms, and kinetic of stromal cell remodeling in FL would be useful to delineate new predictive markers and new therapeutic approaches in this still fatal malignancy

Platinum(II) Complexes with Coordinated Electron-Withdrawing Fluoroalkyl and Fluoroaryl Ligands: Synthesis, Reactivity, and Catalytic Activity

The synthesis, reactivity, and catalytic activity of Pt(II) phosphine complexes containing σ-metal-bound fluoroalkyl and fluoroaryl ligands are surveyed. The increased Pt–C(RF) chemical stability has allowed the isolation and investigation of a series of stable transition-metal hydride, hydroxo, and peroxo complexes. The relative inertness of these complexes coupled with an increased Lewis acidity of the metal center led to the catalytic oxidation of organic substrates (e.g., epoxidation and hydroxylation) in the presence of hydrogen peroxid