186 research outputs found
A Simplified Model for Growth Factor Induced Healing of Wounds
A mathematical model is developed for the rate of healing of a circular or elliptic wound. In this paper the regeneration, decay and transport of a generic \u27growth factor\u27, which induces the healing of the wound, is taken into account. Further, an equation of motion is derived for radial healing of a circular wound. The expressions for the equation of motion and the distribution of the growth factor are related in such a way that no healing occurs if the growth factor concentration at the wound edge is below a threshold value. In this paper we investigate the influence of the behaviour of the thickness of the active layer, in which the growth factor is produced, on the healing process. Also a correction is made to a result in earlier work. Β© 2006 Elsevier Ltd. All rights reserved
ΠΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π»Π΅ΠΏΡΠΈΠ½Π° ΠΈ ΠΈΠ½ΡΠ΅ΡΠ»Π΅ΠΉΠΊΠΈΠ½Π°Β-6 Π² ΡΡΠ²ΠΎΡΠΎΡΠΊΠ΅ ΠΊΡΠΎΠ²ΠΈ Ρ Π±ΠΎΠ»ΡΠ½ΡΡ ΠΏΠΎΠ»ΠΈΡΠ½Π΄ΠΎΠΊΡΠΈΠ½ΠΎΠΏΠ°ΡΠΈΠ΅ΠΉ
Π£ΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½Π° Π²Π·Π°ΠΈΠΌΠΎΡΠ²ΡΠ·Ρ Π»Π΅ΠΏΡΠΈΠ½Π° Ρ ΠΌΠ΅ΡΠ°Π±ΠΎΠ»ΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ ΠΈ Π½Π΅ΠΊΠΎΡΠΎΡΡΠΌΠΈ ΠΈΠΌΠΌΡΠ½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΡΠΌΠΈ Ρ Π±ΠΎΠ»ΡΠ½ΡΡ
ΡΠ°Ρ
Π°ΡΠ½ΡΠΌ Π΄ΠΈΠ°Π±Π΅ΡΠΎΠΌ 2βΠ³ΠΎ ΡΠΈΠΏΠ° Π² ΡΠΎΡΠ΅ΡΠ°Π½ΠΈΠΈ Ρ Π°ΡΡΠΎΠΈΠΌΠΌΡΠ½Π½ΡΠΌ ΡΠΈΡΠ΅ΠΎΠΈΠ΄ΠΈΡΠΎΠΌ. ΠΡΡΠ²Π»Π΅Π½Ρ Π½Π°Π»ΠΈΡΠΈΠ΅ ΠΈΠΌΠΌΡΠ½ΠΎΡΡΠΏΡΠ΅ΡΡΠΈΠΈ ΠΈ ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΠ΅ ΡΡΠΎΠ²Π½Π΅ΠΉ ΠΈΠ½ΡΠ΅ΡΠ»Π΅ΠΉΠΊΠΈΠ½Π°β6 ΠΈ Π»Π΅ΠΏΡΠΈΠ½Π° ΠΏΡΠΈ ΡΠΎΠΏΡΡΡΡΠ²ΡΡΡΠ΅ΠΌ ΠΎΠΆΠΈΡΠ΅Π½ΠΈΠΈ ΠΈ Π΄ΠΈΡΠ»ΠΈΠΏΠΈΠ΄Π΅ΠΌΠΈΠΈ.ΠΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ Π²Π·Π°ΡΠΌΠΎΠ·Π²βΡΠ·ΠΎΠΊ Π»Π΅ΠΏΡΠΈΠ½Ρ Π· ΠΌΠ΅ΡΠ°Π±ΠΎΠ»ΡΡΠ½ΠΈΠΌΠΈ Ρ Π΄Π΅ΡΠΊΠΈΠΌΠΈ ΡΠΌΡΠ½ΠΎΠ»ΠΎΠ³ΡΡΠ½ΠΈΠΌΠΈ ΠΏΠΎΠΊΠ°Π·Π½ΠΈΠΊΠ°ΠΌΠΈ Ρ Ρ
Π²ΠΎΡΠΈΡ
Π½Π° ΡΡΠΊΡΠΎΠ²ΠΈΠΉ Π΄ΡΠ°Π±Π΅Ρ 2βΠ³ΠΎ ΡΠΈΠΏΡ Ρ ΠΏΠΎΡΠ΄Π½Π°Π½Π½Ρ Π· Π°ΡΡΠΎΡΠΌΡΠ½Π½ΠΈΠΌ ΡΠΈΡΠ΅ΠΎΡΠ΄ΠΈΡΠΎΠΌ. ΠΠΈΡΠ²Π»Π΅Π½ΠΎ Π½Π°ΡΠ²Π½ΡΡΡΡ ΡΠΌΡΠ½ΠΎΡΡΠΏΡΠ΅ΡΡΡ ΡΠ° ΠΏΡΠ΄Π²ΠΈΡΠ΅Π½Π½Ρ ΡΡΠ²Π½ΡΠ² ΡΠ½ΡΠ΅ΡΠ»Π΅ΠΉΠΊΡΠ½Ρβ6 Ρ Π»Π΅ΠΏΡΠΈΠ½Ρ ΠΏΡΠΈ ΡΡΠΏΡΡΠ½ΡΠΎΠΌΡ ΠΎΠΆΠΈΡΡΠ½Π½Ρ ΡΠ° Π΄ΠΈΡΠ»ΡΠΏΡΠ΄Π΅ΠΌΡΡ.Association between leptin and some immunological parameters in patients with type 2 diabetes mellitus accompanied by autoimmune thyroiditis was established. The presence of immune suppression and increased levels of interleukinβ6 and leptin was revealed at accompanying obesity and dyslipidemias
Shallow rainwater lenses in deltaic areas with saline seepage
In deltaic areas with saline seepage, freshwater availability is often limited to shallow rainwater lenses lying on top of saline groundwater. Here we describe the characteristics and spatial variability of such lenses in areas with saline seepage and the mechanisms that control their occurrence and size. Our findings are based on different types of field measurements and detailed numerical groundwater models applied in the south-western delta of the Netherlands. By combining the applied techniques we could extrapolate measurements at point scale (groundwater sampling, temperature and electrical soil conductivity (TEC)-probe measurements, electrical cone penetration tests (ECPT)) to field scale (continuous vertical electrical soundings (CVES), electromagnetic survey with EM31), and even to regional scale using helicopter-borne electromagnetic measurements (HEM). The measurements show a gradual mixing zone between infiltrating fresh rainwater and upward flowing saline groundwater. The mixing zone is best characterized by the depth of the centre of the mixing zone <i>D</i><sub>mix</sub>, where the salinity is half that of seepage water, and the bottom of the mixing zone <i>B</i><sub>mix</sub>, with a salinity equal to that of the seepage water (Cl-conc. 10 to 16 g l<sup>β1</sup>). <i>D</i><sub>mix</sub> is found at very shallow depth in the confining top layer, on average at 1.7 m below ground level (b.g.l.), while <i>B</i><sub>mix</sub> lies about 2.5 m b.g.l. The model results show that the constantly alternating upward and downward flow at low velocities in the confining layer is the main mechanism of mixing between rainwater and saline seepage and determines the position and extent of the mixing zone (<i>D</i><sub>mix</sub> and <i>B</i><sub>mix</sub>). Recharge, seepage flux, and drainage depth are the controlling factors
Time-to-birth prediction models and the influence of expert opinions
Preterm birth is the leading cause of death among children under five years old. The pathophysiology and etiology of preterm labor are not yet fully understood. This causes a large number of unnecessary hospitalizations due to high--sensitivity clinical policies, which has a significant psychological and economic impact. In this study, we present a predictive model, based on a new dataset containing information of 1,243 admissions, that predicts whether a patient will give birth within a given time after admission. Such a model could provide support in the clinical decision-making process. Predictions for birth within 48 h or 7 days after admission yield an Area Under the Curve of the Receiver Operating Characteristic (AUC) of 0.72 for both tasks. Furthermore, we show that by incorporating predictions made by experts at admission, which introduces a potential bias, the prediction effectiveness increases to an AUC score of 0.83 and 0.81 for these respective tasks
Bend it like Beckham: embodying the motor skills of famous athletes.
Observing an action activates the same representations as does the actual performance of the action. Here we show for the first time that the action system can also be activated in the complete absence of action perception. When the participants had to identify the faces of famous athletes, the responses were influenced by their similarity to the motor skills of the athletes. Thus, the motor skills of the viewed athletes were retrieved automatically during person identification and had a direct influence on the action system of the observer. However, our results also indicated that motor behaviours that are implicit characteristics of other people are represented differently from when actions are directly observed. That is, unlike the facilitatory effects reported when actions were seen, the embodiment of the motor behaviour that is not concurrently perceived gave rise to contrast effects where responses similar to the behaviour of the athletes were inhibited
Capuchin monkeys display affiliation toward humans who imitate them
During social interactions, humans often unconsciously and unintentionally imitate the behaviors of others, which increases rapport, liking, and empathy between interaction partners. This effect is thought to be an evolutionary adaptation facilitating group living, and may therefore be shared with other primate species. Here we show that capuchin monkeys, a highly social primate species, prefer human imitators in a variety of ways: they look longer at imitators, spend more time in proximity to imitators, and choose to interact more frequently with imitators in a token exchange task. These results demonstrate that imitation can promote affiliation in nonhuman primates. Behavior matching that leads to prosocial behaviors towards others may have been one of the mechanisms at the basis of altruistic behavioral tendencies in capuchins and in other primates including humans
Because itβs good for my feeling of self-worth:Testing the expanded theory of planned behavior to predict Greek usersβ intention to review mobile apps
Π ΠΎΠ»Ρ ΡΡΡΠ°Π΄Π°ΡΡΠ΅ΠΉ Π΄Π΅ΠΏΡΠ΅ΡΡΠΈΠ΅ΠΉ ΠΌΠ°ΡΠ΅ΡΠΈ Π² ΡΠ°Π·Π²ΠΈΡΠΈΠΈ Π»ΠΈΡΠ½ΠΎΡΡΠΈ ΡΠ΅Π±Π΅Π½ΠΊΠ°
Π‘ ΠΏΠΎΠ·ΠΈΡΠΈΠΉ ΠΏΡΠΈΡ
ΠΎΠ΄ΠΈΠ½Π°ΠΌΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Π° ΠΏΠΎΠΊΠ°Π·Π°Π½Π° ΡΠΎΠ»Ρ ΡΡΡΠ°Π΄Π°ΡΡΠ΅ΠΉ Π΄Π΅ΠΏΡΠ΅ΡΡΠΈΠ΅ΠΉ ΠΌΠ°ΡΠ΅ΡΠΈ Π² ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ Π»ΠΈΡΠ½ΠΎΡΡΠΈ ΡΠ΅Π±Π΅Π½ΠΊΠ° Π½Π° ΠΏΠ΅ΡΠ²ΡΡ
ΡΡΠ°ΠΏΠ°Ρ
Π΅Π³ΠΎ ΠΏΠΎΡΡΠ½Π°ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΈ Π΅Π΅ Π²Π»ΠΈΡΠ½ΠΈΠ΅ Π½Π° Π΅Π³ΠΎ ΠΏΡΠΈΡ
ΠΈΡΠ΅ΡΠΊΠΎΠ΅ Π·Π΄ΠΎΡΠΎΠ²ΡΠ΅ Π² Π΄Π°Π»ΡΠ½Π΅ΠΉΡΠ΅ΠΌ.The role of the mother with depression in development of the child's personality at the first stages of the postnatal period as well as its influence on his/her mental state in future are shown from the perspective of a psychodynamic approach
The bodily social self: a link between phenomenal and narrative selfhood
The Phenomenal Self (PS) is widely considered to be dependent on body representations, whereas the Narrative Self (NS) is generally thought to rely on abstract cognitive representations. The concept of the Bodily Social Self (BSS) might play an important role in explaining how the high level cognitive self-representations enabling the NS might emerge from the bodily basis of the PS. First, the phenomenal self (PS) and narrative self (NS), are briefly examined. Next, the BSS is defined and its potential for explaining aspects of social cognition is explored. The minimal requirements for a BSS are considered, before reviewing empirical evidence regarding the development of the BSS over the first year of life. Finally, evidence on the involvement of the body in social distinctions between self and other is reviewed to illustrate how the BSS is affected by both the bottom up effects of multisensory stimulation and the top down effects of social identification
Opties voor een klimaatbestendige zoetwatervoorziening in Laag Nederland, tussentijds integratierapport
Dit rapport geeft een tussentijds overzicht van βstate of the artβ kennis uit lopend onderzoek van het consortium βClimate Proof Fresh Water Supplyβ (CPFWS) dat in het kader van het onderzoeksprogramma Kennis voor Klimaat wordt uitgevoerd. De focus van dit onderzoek naar een klimaatbestendige zoetwatervoorziening ligt op lokale en regionale oplossingen in Laag Nederland voor land- en tuinbouw en natuur. De zoetwatervoorziening van dit gebied wordt naast droogte vooral bedreigd door verzilting van grond- en oppervlaktewater. In zes samenhangende werkpakketten wordt geanalyseerd hoe dit gebied meer zelfvoorzienend kan worden Γ©n hoe aanpassingen in het (hoofd)watersysteem kunnen bijdragen aan de watervoorziening van het gebied. Centraal in de aanpak zijn een 3-tal casestudies in de Hotspots Haaglanden, Rotterdam Regio en Zuidwestelijke delta
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