Anthropometric Characteristics, Body Composition and Somatotype of Elite Pan-American Race Walking 20K

The anthropometric and somatotype evaluation is an essential tool in the selection and control of high-performance athletes. The aim of this study was to describe the somatotype and body composition of male elite race walkers (20 k modality), and its relationship with athletic performance. Twenty-four race walkers participated in this study. The sample was divided into two groups: the race walkers with the best performance (upper 25 percentile; n=7) and the second group (n=17) that corresponds to the rest of the participants. Weight (kg), height (cm), seven skinfolds, two diameters and five perimeters were measured. Body fat percentage (BF%) were estimated with the Yuhasz formula, and the somatotype was used applying the Heath-Carter method. The best performing athletes were taller (178.3 +/- 4.4 cm vs. 173.7 +/- 5.6 cm, p<0.05) and showed a greater ectomorphic component (p<0.05) than the rest of the participants. The somatotype of the best performance athletes was 2.2-2.8-4.1 against the 2.5-3.8-2.9 of the lowest performing athletes. The average time (hours, minute, seconds) of execution of the race in athletes of better performances was 1: 22:40, in comparison with the athletes of lower performances with 1: 32: 41 (p<0.02). The ectomorphic component and height are morphological characteristics that can determine athletic performance of race walkers. It is suggested to consider these factors in the selection of the race walkers. La evaluación antropométrica y del somatotipo es una importante herramienta en la selección y control de los atletas de alto rendimiento. El objetivo de este estudio fue describir el somatotipo y composición corporal de hombres marchistas olímpicos, modalidad 20 k, y su relación con el rendimiento atlético. Veinticuatro atletas de marcha participaron en este estudio. La muestra fue dividida en dos grupos: los marchistas de mejores rendimientos p25 superior (n=7) y el segundo grupo (n=17) que corresponde al resto de los participantes. Se registró el peso (kg), talla (cm), siete pliegues cutáneos, dos diámetros y cinco perímetros. Se estimó el porcentaje de grasa corporal (%GC) con la fórmula de Yuhasz y se describió el somatotipo utilizando el método de Heath-Carter. Se reporta una mayor altura en los atletas de mejor rendimiento (178,3±4,4 cm vs. 173,7±5,6 cm; p<0,05) y mayor componente ectomorfico (p<0,05) que el resto de los participantes. El somatotipo de los atletas de mejor rendimiento fue de 2.2-2.8-4.1 frente al 2.5-3.8-2.9 de los atletas de menor rendimiento. El tiempo promedio (hora, minuto, segundo) de ejecución de la carrera en atletas de mejores rendimientos fue de 1:22:40, en comparación con los atletas de menores rendimientos con 1:32:41 (p <0,02). El componente ectomórfico y altura serian características morfológicas que pueden determinar el rendimiento deportivo de atletas de marcha. Se sugiere considerar estos factores en la selección de los marchistas olímpicos

Mitigation of Moral Hazard and Adverse Selection in Venture Capital Financing: The Influence of the Country’s Institutional Setting

A venture capitalist (VC) needs to trade off benefits and costs when attempting to mitigate agency problems in their investor-investee relationship. We argue that signals of ventures complement the VC’s capacity to screen and conduct a due diligence during the pre-investment phase, but its attractiveness may diminish in institutional settings supporting greater transparency. Similarly, whereas a VC may opt for contractual covenants to curb potential opportunism by ventures in the post-investment phase, this may only be effective in settings supportive of shareholder rights enforcement. Using an international sample of VC contracts, our study finds broad support for these conjectures. It delineates theoretical and practical implications for how investors can best deploy their capital in different institutional settings whilst nurturing their relationships with entrepreneurs

Corporate governance and financial constraints on strategic turnarounds

The paper extends the Robbins and Pearce (1992) two-stage turnaround response model to include governance factors. In addition to the retrenchment and recovery, the paper proposes the addition of a realignment stage, referring specifically to the re-alignment of expectations of principal and agent groups. The realignment stage imposes a threshold that must be crossed before the retrenchment and hence recovery stage can be entered. Crossing this threshold is problematic to the extent that the interests of governance-stakeholder groups diverge in a crisis situation. The severity of the crisis impacts on the bases of strategy contingent asset valuation leading to the fragmentation of stakeholder interests. In some cases the consequence may be that management are prevented from carrying out turnarounds by governance constraints. The paper uses a case study to illustrate these dynamics, and like the Robbins and Pearce study, it focuses on the textile industry. A longitudinal approach is used to show the impact of the removal of governance constraints. The empirical evidence suggests that such financial constraints become less serious to the extent that there is a functioning market for corporate control. Building on governance research and turnaround literature, the paper also outlines the general case necessary and sufficient conditions for successful turnarounds

Higher Doses of Subcutaneous IgG Reduce Resource Utilization in Patients with Primary Immunodeficiency

The recommended dose of IgG in primary immunodeficiency (PID) has been increasing since its first use. This study aimed to determine if higher subcutaneous IgG doses resulted in improved patient outcomes by comparing results from two parallel clinical studies with similar design. One patient cohort received subcutaneous IgG doses that were 1.5 times higher than their previous intravenous doses (mean 213 mg/kg/week), whereas the other cohort received doses identical to previous subcutaneous or intravenous doses (mean 120 mg/kg/week). While neither cohort had any serious infections, the cohort maintained on higher mean IgG dose had significantly lower rates of non-serious infections (2.76 vs. 5.18 episodes/year, P < 0.0001), hospitalization (0.20 vs. 3.48 days/year, P < 0.0001), antibiotic use (48.50 vs. 72.75 days/year, P < 0.001), and missed work/school activity (2.10 vs. 8.00 days/year, P < 0.001). The higher-dose cohort had lower health care utilization and improved indices of well being compared to the cohort treated with traditional IgG doses

Quasi-autonomous quantum thermal machines and quantum to classical energy flow

There are both practical and foundational motivations to consider the thermodynamics of quantum systems at small scales. Here we address the issue of autonomous quantum thermal machines that are tailored to achieve some specific thermodynamic primitive, such as work extraction in the presence of a thermal environment, while having minimal or no control from the macroscopic regime. Beyond experimental implementations, this provides an arena in which to address certain foundational aspects such as the role of coherence in thermodynamics, the use of clock degrees of freedom and the simulation of local time-dependent Hamiltonians in a particular quantum subsystem. For small-scale systems additional issues arise. Firstly, it is not clear to what degree genuine ordered thermodynamic work has been extracted, and secondly non-trivial back-actions on the thermal machine must be accounted for. We find that both these aspects can be resolved through a judicious choice of quantum measurements that magnify thermodynamic properties up the ladder of length-scales, while simultaneously stabilising the quantum thermal machine. Within this framework we show that thermodynamic reversibility is obtained in a particular Zeno limit, and finally illustrate these concepts with a concrete example involving spin systems

The clinical utility of molecular diagnostic testing for primary immune deficiency disorders: a case based review

Primary immune deficiency disorders (PIDs) are a group of diseases associated with a genetic predisposition to recurrent infections, malignancy, autoimmunity and allergy. The molecular basis of many of these disorders has been identified in the last two decades. Most are inherited as single gene defects. Identifying the underlying genetic defect plays a critical role in patient management including diagnosis, family studies, prognostic information, prenatal diagnosis and is useful in defining new diseases. In this review we outline the clinical utility of molecular testing for these disorders using clinical cases referred to Auckland Hospital. It is written from the perspective of a laboratory offering a wide range of tests for a small developed country

Financing micro-entrepreneurs for poverty alleviation: a performance analysis of microfinance services offered by BRAC, ASA, and Proshika from Bangladesh

Microfinance services have emerged as an effective tool for financing microentrepreneurs to alleviate poverty. Since the 1970s, development theorists have considered non-governmental microfinance institutions (MFIs) as the leading practitioners of sustainable development through financing micro-entrepreneurial activities. This study evaluates the impact of micro-finance services provided by MFIs on poverty alleviation. In this vein, we examine whether microfinance services contribute to poverty alleviation, and also identify bottlenecks in micro-finance programs and operations. The results indicate that the micro-loans have a statistically significant positive impact on the poverty alleviation index and consequently improve the living standard of borrowers by increasing their level of income

Febrile seizures and mechanisms of epileptogenesis: insights from an animal model.

Temporal lobe epilepsy (TLE) is the most prevalent type of human epilepsy, yet the causes for its development, and the processes involved, are not known. Most individuals with TLE do not have a family history, suggesting that this limbic epilepsy is a consequence of acquired rather than genetic causes. Among suspected etiologies, febrile seizures have frequently been cited. This is due to the fact that retrospective analyses of adults with TLE have demonstrated a high prevalence (20--&gt;60%) of a history of prolonged febrile seizures during early childhood, suggesting an etiological role for these seizures in the development of TLE. Specifically, neuronal damage induced by febrile seizures has been suggested as a mechanism for the development of mesial temporal sclerosis, the pathological hallmark of TLE. However, the statistical correlation between febrile seizures and TLE does not necessarily indicate a causal relationship. For example, preexisting (genetic or acquired) 'causes' that result independently in febrile seizures and in TLE would also result in tight statistical correlation. For obvious reasons, complex febrile seizures cannot be induced in the human, and studies of their mechanisms and of their consequences on brain molecules and circuits are severely limited. Therefore, an animal model was designed to study these seizures. The model reproduces the fundamental key elements of the human condition: the age specificity, the physiological temperatures seen in fevers of children, the length of the seizures and their lack of immediate morbidity. Neuroanatomical, molecular and functional methods have been used in this model to determine the consequences of prolonged febrile seizures on the survival and integrity of neurons, and on hyperexcitability in the hippocampal-limbic network. Experimental prolonged febrile seizures did not lead to death of any of the seizure-vulnerable populations in hippocampus, and the rate of neurogenesis was also unchanged. Neuronal function was altered sufficiently to promote synaptic reorganization of granule cells, and transient and long-term alterations in the expression of specific genes were observed. The contribution of these consequences of febrile seizures to the epileptogenic process is discussed