9,555 research outputs found
Structures in magnetohydrodynamic turbulence: detection and scaling
We present a systematic analysis of statistical properties of turbulent
current and vorticity structures at a given time using cluster analysis. The
data stems from numerical simulations of decaying three-dimensional (3D)
magnetohydrodynamic turbulence in the absence of an imposed uniform magnetic
field; the magnetic Prandtl number is taken equal to unity, and we use a
periodic box with grids of up to 1536^3 points, and with Taylor Reynolds
numbers up to 1100. The initial conditions are either an X-point configuration
embedded in 3D, the so-called Orszag-Tang vortex, or an
Arn'old-Beltrami-Childress configuration with a fully helical velocity and
magnetic field. In each case two snapshots are analyzed, separated by one
turn-over time, starting just after the peak of dissipation. We show that the
algorithm is able to select a large number of structures (in excess of 8,000)
for each snapshot and that the statistical properties of these clusters are
remarkably similar for the two snapshots as well as for the two flows under
study in terms of scaling laws for the cluster characteristics, with the
structures in the vorticity and in the current behaving in the same way. We
also study the effect of Reynolds number on cluster statistics, and we finally
analyze the properties of these clusters in terms of their velocity-magnetic
field correlation. Self-organized criticality features have been identified in
the dissipative range of scales. A different scaling arises in the inertial
range, which cannot be identified for the moment with a known self-organized
criticality class consistent with MHD. We suggest that this range can be
governed by turbulence dynamics as opposed to criticality, and propose an
interpretation of intermittency in terms of propagation of local instabilities.Comment: 17 pages, 9 figures, 5 table
Detecting bit-flip errors in a logical qubit using stabilizer measurements
Quantum data is susceptible to decoherence induced by the environment and to
errors in the hardware processing it. A future fault-tolerant quantum computer
will use quantum error correction (QEC) to actively protect against both. In
the smallest QEC codes, the information in one logical qubit is encoded in a
two-dimensional subspace of a larger Hilbert space of multiple physical qubits.
For each code, a set of non-demolition multi-qubit measurements, termed
stabilizers, can discretize and signal physical qubit errors without collapsing
the encoded information. Experimental demonstrations of QEC to date, using
nuclear magnetic resonance, trapped ions, photons, superconducting qubits, and
NV centers in diamond, have circumvented stabilizers at the cost of decoding at
the end of a QEC cycle. This decoding leaves the quantum information vulnerable
to physical qubit errors until re-encoding, violating a basic requirement for
fault tolerance. Using a five-qubit superconducting processor, we realize the
two parity measurements comprising the stabilizers of the three-qubit
repetition code protecting one logical qubit from physical bit-flip errors. We
construct these stabilizers as parallelized indirect measurements using
ancillary qubits, and evidence their non-demolition character by generating
three-qubit entanglement from superposition states. We demonstrate
stabilizer-based quantum error detection (QED) by subjecting a logical qubit to
coherent and incoherent bit-flip errors on its constituent physical qubits.
While increased physical qubit coherence times and shorter QED blocks are
required to actively safeguard quantum information, this demonstration is a
critical step toward larger codes based on multiple parity measurements.Comment: 6 pages, 4 figures, 10 supplementary figure
Giant magnetic enhancement in Fe/Pd films and its influence on the magnetic interlayer coupling
The magnetic properties of thin Pd fcc(001) films with embedded monolayers of
Fe are investigated by means of first principles density functional theory. The
induced spin polarization in Pd is calculated and analyzed in terms of quantum
interference within the Fe/Pd/Fe bilayer system. An investigation of the
magnetic enhancement effects on the spin polarization is carried out and its
consequences for the magnetic interlayer coupling are discussed. In contrast to
{\it e.g.} the Co/Cu fcc(001) system we find a large effect on the magnetic
interlayer coupling due to magnetic enhancement in the spacer material. In the
case of a single embedded Fe monolayer we find aninduced Pd magnetization
decaying with distance from the magnetic layer as ~ with
. For the bilayer system we find a giant magnetic
enhancement (GME) that oscillates strongly due to interference effects. This
results in a strongly modified magnetic interlayer coupling, both in phase and
magnitude, which may not be described in the pure
Ruderman-Kittel-Kasuya-Yoshida (RKKY) picture. No anti-ferromagnetic coupling
was found and by comparison with magnetically constrained calculations we show
that the overall ferromagnetic coupling can be understood from the strong
polarization of the Pd spacer
Exhaustive and Efficient Constraint Propagation: A Semi-Supervised Learning Perspective and Its Applications
This paper presents a novel pairwise constraint propagation approach by
decomposing the challenging constraint propagation problem into a set of
independent semi-supervised learning subproblems which can be solved in
quadratic time using label propagation based on k-nearest neighbor graphs.
Considering that this time cost is proportional to the number of all possible
pairwise constraints, our approach actually provides an efficient solution for
exhaustively propagating pairwise constraints throughout the entire dataset.
The resulting exhaustive set of propagated pairwise constraints are further
used to adjust the similarity matrix for constrained spectral clustering. Other
than the traditional constraint propagation on single-source data, our approach
is also extended to more challenging constraint propagation on multi-source
data where each pairwise constraint is defined over a pair of data points from
different sources. This multi-source constraint propagation has an important
application to cross-modal multimedia retrieval. Extensive results have shown
the superior performance of our approach.Comment: The short version of this paper appears as oral paper in ECCV 201
Quantum harmonic oscillator systems with disorder
We study many-body properties of quantum harmonic oscillator lattices with
disorder. A sufficient condition for dynamical localization, expressed as a
zero-velocity Lieb-Robinson bound, is formulated in terms of the decay of the
eigenfunction correlators for an effective one-particle Hamiltonian. We show
how state-of-the-art techniques for proving Anderson localization can be used
to prove that these properties hold in a number of standard models. We also
derive bounds on the static and dynamic correlation functions at both zero and
positive temperature in terms of one-particle eigenfunction correlators. In
particular, we show that static correlations decay exponentially fast if the
corresponding effective one-particle Hamiltonian exhibits localization at low
energies, regardless of whether there is a gap in the spectrum above the ground
state or not. Our results apply to finite as well as to infinite oscillator
systems. The eigenfunction correlators that appear are more general than those
previously studied in the literature. In particular, we must allow for
functions of the Hamiltonian that have a singularity at the bottom of the
spectrum. We prove exponential bounds for such correlators for some of the
standard models
Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma
Published in final edited form as: Sci Transl Med. 2017 May 10; 9(389). https://doi.org/10.1126/scitranslmed.aal2668.Multiple myeloma (MM) is a frequently incurable hematological cancer in which overactivity of MYC plays a central role, notably through up-regulation of ribosome biogenesis and translation. To better understand the oncogenic program driven by MYC and investigate its potential as a therapeutic target, we screened a chemically diverse small-molecule library for anti-MM activity. The most potent hits identified were rocaglate scaffold inhibitors of translation initiation. Expression profiling of MM cells revealed reversion of the oncogenic MYC-driven transcriptional program by CMLD010509, the most promising rocaglate. Proteome-wide reversion correlated with selective depletion of short-lived proteins that are key to MM growth and survival, most notably MYC, MDM2, CCND1, MAF, and MCL-1. The efficacy of CMLD010509 in mouse models of MM confirmed the therapeutic relevance of these findings in vivo and supports the feasibility of targeting the oncogenic MYC-driven translation program in MM with rocaglates
PRESENCE OF AVIAN INFLUENZA VIRUS IN WILD BIRDS IN THE WETLANDS OF PUERTO VIEJO, LIMA
El objetivo del estudio fue determinar la presencia del virus de influenza aviar (IA) en aves silvestres presentes en los Humedales de Puerto Viejo, en el departamento de Lima. Novecientas muestras de heces frescas de 18 especies de aves silvestres fueron colectadas desde abril de 2008 hasta febrero de 2009. Dichas muestras se analizaron mediante aislamiento viral en huevos embrionados de pollo SPF. Se logró aislar siete cepas de virus de IA de baja patogenicidad del subtipo H12N5 (seis cepas procedentes de la especie migratoria Arenaria interpres y una de la especie residente Fulica ardesiaca). La técnica de evaluación de riesgo mediante la simulación de Monte Carlo (programa @risk) indicó que la probabilidad de encontrar el virus de Influenza A en las aves silvestres de los Humedales de Puerto Viejo es de 0.88% con un intervalo de confianza de 0.15 a 2.53%. Los resultados demuestran que las aves silvestres de los Humedales de Puerto Viejo constituyen un reservorio para los virus de influenza aviar en el Perú.The objective of the study was to detect the presence of avian influenza (AI) virus in wild aquatic birds found in Puerto Viejo wetlands, Lima-Peru. Fresh faecal samples (n=900) from 18 species of wild birds were collected from April 2008 to February 2009. Samples were analyzed by virus isolation in SPF embryonated chicken eggs. Seven strains of low pathogenicity AI viruses subtype H12N5 were isolated; six from the migratory species Arenaria interpres, and one from the resident species Fulica ardesiaca. The technique of risk assessment using Monte Carlo Simulation (program @ risk) indicated that the probability of finding the AI virus in wild birds from Puerto Viejo wetlands was 0.88% with a confidence interval of 0.15 to 2.53%. The results of the study showed that wild birds from Puerto Viejo wetlands constitute a reservoir for avian influenza virus in Peru
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