THE APPLICATION OF THINK-TALK-WRITE STRATEGY TO IMPROVE THE TENTH GRADE OF SMA SANTO YOSEPH MEDAN STUDENTS’ SKILL IN WRITING RECOUNT TEXT

The aim of this study is to find whether Think – Talk – Write Strategy works effectively on improving the tenth grade students’ achievement in writing recount texts and to know the students’ responses after being taught by using Think – Talk – Write Strategy . in order to  achieve the objectives of study, a classroom action research was designed and carried out in this study. The subjects of this study were 32 students of class X- MIA2  OF SMA Santo Yoseph Medan in academic year 2018/2019. Test, observation sheet, and field notes were used as a instruments for collecting data. The results of the study showed significant improvement of the students’ skill in writing. It is proved by the students’ mean score of each test: pre-test was 57,5%, formative test was 67,22% and post-test  was 83,88% . In addition, the, the analysis result of the observation sheet and field notes showed Think – Talk – Write Strategy channge the students’ learning behavior being better than before. They were more enthusiastic during the teaching learning process in each cycle. The analysis result of questionnaire showed that Think – Talk – Write Strategy was useful to most of students to improve their learnig interest in writing recount text. Based on the results of those study instruments, it can be concluded that Think – Talk – Write Strategy as learning strategy gives the improvement to students’ skill in writing recount text. It is recommended for English teacher to apply Think – Talk – Write Strategy in teaching writing skill in order to improve students’ skill in writing expecially recount text.Â

Hubungan Sikap Ibu dan Dukungan Keluarga dengan Kelengkapan Imunisasi Lanjutan pada Baduta di Puskesmas Amplas Kecamatan Medan Amplas Tahun 2022

Background: Many factors influence the completeness of basic immunization, such as parents, geographical location, vaccines, and health workers who provide immunization services. Even though the immunization program has been implemented well, there are still some immunization coverage that have not been achieved. Parents are the most important factor in scoring a child's complete immunization. Parents' participation in a health program is influenced by various factors and one of them is knowledge and attitudes towards the health program itself. Giving vaccines to children is the right way to anticipate the possibility of children being infected with diseases that are threatening at any time. Immunization functions to build a child's immunity against infectious diseases and dangerous diseases that can cause bodily defects. even death. Immunization given to children is the most effective way to protect children from tuberculosis (TB), diphtheria, pertussis (cocoon cough), tetanus (toothbrush). poliomyletis, measles, rubella and hepatitis B (Mai-imbi, 2021). During this time, parents had hepatitis B, meningitis, pneumonia and polio. VPD is a disease that is hoped to be eradicated or suppressed by implementing an immunization program Objective: Knowing the relationship between maternal attitudes and family support with the completeness of follow-up immunizations for young children at the Medan Amplas Community Health Center, Medan Amplas District in 2022. Method chi square test p value < 0.05 means H0 is rejected and Ha is accepted, the statistical test results show a significant relationship. Results: There is a relationship between the mother's attitude of family support and the completeness of advanced immunization for children in 2022. Suggestions are provided for research and for research sites and for educational institutions regarding perennial wound care

IMPROVING THE STUDENTS’ READING COMPREHENSION BY USING PQ4R STRATEGY TO THE EIGHTH GRADE AT SMP NEGERI 2 PANCUR BATU

 Reading is one of the four language skills in English, they are listening, speaking, reading and writing. The students get bored in reading comprehension. Since they do not understand the text. Thus, they need some ways or strategy which could help students’s reading comprehension on narrative text. The teacher should be creative to search for interesting strategy to teach reading comprehension on narrative text. PQ4R strategy can helps the students to understand on narrative text. The objectives of this study to find out the students’ reading comprehension bu using PQ4R strategy. The subject of this study were the eight grade students of SMP 2 Negeri Pancur Batu. This research, the writer used Classroom Action Research (CAR) as the method of research. Tests were used to gather the quantitative data. Based on the finding of this study, it showed in pre-test only 4 students (11%) who passed KKM ( the Mastery Minimum Criteria), and  post test 25 students (71%). The result of this research revealed that there was a significant improvement of the students’ achievement from the pre-test to in the post test. This improvement was shown by the comparison between the mean score of pre-test (51,2), and post test (73,82). Furthermore, the students were interested in PQ4R strategy, it can be seen from the result of observation sheet and questionnaire .Therefore, PQ4R startegy was effective strategy in helping students to improve their reading comprehension especially in narrative text

IMPROVING THE ELEVENTH GRADE STUDENTS’ SPEAKING SKILL BY USING AUDIO VISUAL AIDS IN SMA SANTO PETRUS MEDAN IN THE ACADEMIC YEAR OF 2018/2019

Communication is very significant for human being because there is hardly any human activity without communication. This research is Classroom Action Research (CAR) which was conducted to improve the eleventh grade students’ speaking skill by using audio visual aids in SMA Santo Petrus Medan in the Academic Year of 2018/2019. The results of the study showed significant improvement of the students’ speaking skill and responses after being taught by using audio visual aids is very good because the students felt enthusiastics and motivated. The result of the test showed that the students’ mean score in pre-test is 51,97 with 8,82% of the students got score ≥ 75, in formative-test mean score is 60,70 with 14,70% of the students got score ≥ 75 and in post-test mean score is 75,35 with 44,11% of the students got score ≥ 75. Based on the results, it can be concluded that using audio visual aids as a learning a instrument gives the improvement to students’ speaking skill

Menganalisis Kesalahan Siswa SMP dalam Mengulas Buku

Penelitian ini bertujuan untuk menjelaskan kesalahan dan kesulitan dalam mengulas buku pada siswa kelas VIII SMP Negeri 2 Kotagajah. Penelitian ini memiliki manfaat yang dapat digunakan untuk mengetahui kesalahan atau pun kesulitan siswa yang sering terjadi ketika mengulas sebuah buku. Selain itu juga dapat memberikan solusi terkait permasalahan yang dialami siswa. Penelitian ini merupakan studi kasus dengan data penelitian berupa kesalahan dan kesulitan siswa dalam mengulas sebuah buku. Teknik analisis data menggunakan analisis isi. Hasil penelitian ditemukan Berdasarkan hasil penelitian diketahui bahwa kemampuan menulis teks ulasan/resensi siswa kelas VIII SMP Negeri 2 Kotagajah tahun pelajaran 2014/2015 untuk aspek penyusunan struktur tergolong baik sekali dengan persentase 92%. Kemampuan menulis teks ulasan/resensi berdasarkan penyusunan struktur dapat diketahui bahwa siswa yang mendapat nilai denga kategori baik sekali berjumlah 53 orang (88%), siswa yang mendapatkan nilai dengan kategori baik, cukup, dan kurang tidak ada (0%), dan siswa yang mendapatkan nilai dengan kategori kurang sekali berjumlah 7 orang (12%)

Menganalisis Kesalahan Siswa SMP dalam Mengulas Buku

Penelitian ini bertujuan untuk menjelaskan kesalahan dan kesulitan dalam mengulas buku pada siswa kelas VIII SMP Negeri 2 Kotagajah. Penelitian ini memiliki manfaat yang dapat digunakan untuk mengetahui kesalahan atau pun kesulitan siswa yang sering terjadi ketika mengulas sebuah buku. Selain itu juga dapat memberikan solusi terkait permasalahan yang dialami siswa. Penelitian ini merupakan studi kasus dengan data penelitian berupa kesalahan dan kesulitan siswa dalam mengulas sebuah buku. Teknik analisis data menggunakan analisis isi. Hasil penelitian ditemukan Berdasarkan hasil penelitian diketahui bahwa kemampuan menulis teks ulasan/resensi siswa kelas VIII SMP Negeri 2 Kotagajah tahun pelajaran 2014/2015 untuk aspek penyusunan struktur tergolong baik sekali dengan persentase 92%. Kemampuan menulis teks ulasan/resensi berdasarkan penyusunan struktur dapat diketahui bahwa siswa yang mendapat nilai denga kategori baik sekali berjumlah 53 orang (88%), siswa yang mendapatkan nilai dengan kategori baik, cukup, dan kurang tidak ada (0%), dan siswa yang mendapatkan nilai dengan kategori kurang sekali berjumlah 7 orang (12%)

Rasio Likuiditas, Manajemen Asset, Manajemen Utang, Aktivitas untuk Mengukur Kinerja Keungan Perusahaan Pertambangan di Bursa Efek Indonesia

This study aims to determine the partial impact of liquidity ratios, asset management, debt management, and activities on the financial performance of mining sub-sector companies listed on the IDX for the period 2017-2019. This research method is descriptive quantitative. Study data obtained is an annual report contained in the IDX. There are 47 companies listed on the IDX as the population used by the authors in this study. The results showed, a) the CR variable has a value of t count < t table that is -0.534 < - 2.00172 with a significant value of 0.596 > 0.05; b) TATO variable has a value of t count < t table that is 0.482 < 2.0172 with a significant value of 0.000 < 0.05; c) the DAR variable has a value of t count < t table, namely -1.635 < - 2.0172 with a significant value of 0.107 > 0.05; d) the FATO variable has a value of t count < t table that is 1.755 < 2.0172 with a significant value of 0.085 > 0.05. All independent variables affect the dependent variable which can be seen from the determination coefficient test of 46.4% of financial performance which can be clarified by four independent variables. In conclusion, financial performance is significantly influenced by liquidity ratios, asset management, debt management, and activities.  Keywords: Activities, Financial Performance, Asset Management, Debt Management, Liquidity Rati

Toxic Epidermal Necrolysis after Pemetrexed and Cisplatin for Non-Small Cell Lung Cancer in a Patient with Sharp Syndrome

Background: Pemetrexed is an antifolate drug approved for maintenance and second-line therapy, and, in combination with cisplatin, for first-line treatment of advanced nonsquamous non-small cell lung cancer. The side-effect profile includes fatigue, hematological and gastrointestinal toxicity, an increase in hepatic enzymes, sensory neuropathy, and pulmonary and cutaneous toxicity in various degrees. Case Report: We present the case of a 58-year-old woman with history of Sharp's syndrome and adenocarcinoma of the lung, who developed toxic epidermal necrolysis after the first cycle of pemetrexed, including erythema, bullae, extensive skin denudation, subsequent systemic inflammation and severe deterioration in general condition. The generalized skin lesions occurred primarily in the previous radiation field and responded to immunosuppressive treatment with prednisone. Conclusion: Although skin toxicity is a well-known side effect of pemetrexed, severe skin reactions after pemetrexed administration are rare. Caution should be applied in cases in which pemetrexed is given subsequent to radiation therapy, especially in patients with pre-existing skin diseases

A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling.

Mechanisms that integrate the metabolic state of a cell with regulatory pathways are necessary to maintain cellular homeostasis. Endogenous, intrinsically reactive metabolites can form functional, covalent modifications on proteins without the aid of enzymes1,2, and regulate cellular functions such as metabolism3-5 and transcription6. An important 'sensor' protein that captures specific metabolic information and transforms it into an appropriate response is KEAP1, which contains reactive cysteine residues that collectively act as an electrophile sensor tuned to respond to reactive species resulting from endogenous and xenobiotic molecules. Covalent modification of KEAP1 results in reduced ubiquitination and the accumulation of NRF27,8, which then initiates the transcription of cytoprotective genes at antioxidant-response element loci. Here we identify a small-molecule inhibitor of the glycolytic enzyme PGK1, and reveal a direct link between glycolysis and NRF2 signalling. Inhibition of PGK1 results in accumulation of the reactive metabolite methylglyoxal, which selectively modifies KEAP1 to form a methylimidazole crosslink between proximal cysteine and arginine residues (MICA). This posttranslational modification results in the dimerization of KEAP1, the accumulation of NRF2 and activation of the NRF2 transcriptional program. These results demonstrate the existence of direct inter-pathway communication between glycolysis and the KEAP1-NRF2 transcriptional axis, provide insight into the metabolic regulation of the cellular stress response, and suggest a therapeutic strategy for controlling the cytoprotective antioxidant response in several human diseases

Cold gas accretion in galaxies

Evidence for the accretion of cold gas in galaxies has been rapidly accumulating in the past years. HI observations of galaxies and their environment have brought to light new facts and phenomena which are evidence of ongoing or recent accretion: 1) A large number of galaxies are accompanied by gas-rich dwarfs or are surrounded by HI cloud complexes, tails and filaments. It may be regarded as direct evidence of cold gas accretion in the local universe. It is probably the same kind of phenomenon of material infall as the stellar streams observed in the halos of our galaxy and M31. 2) Considerable amounts of extra-planar HI have been found in nearby spiral galaxies. While a large fraction of this gas is produced by galactic fountains, it is likely that a part of it is of extragalactic origin. 3) Spirals are known to have extended and warped outer layers of HI. It is not clear how these have formed, and how and for how long the warps can be sustained. Gas infall has been proposed as the origin. 4) The majority of galactic disks are lopsided in their morphology as well as in their kinematics. Also here recent accretion has been advocated as a possible cause. In our view, accretion takes place both through the arrival and merging of gas-rich satellites and through gas infall from the intergalactic medium (IGM). The infall may have observable effects on the disk such as bursts of star formation and lopsidedness. We infer a mean ``visible'' accretion rate of cold gas in galaxies of at least 0.2 Msol/yr. In order to reach the accretion rates needed to sustain the observed star formation (~1 Msol/yr), additional infall of large amounts of gas from the IGM seems to be required.Comment: To appear in Astronomy & Astrophysics Reviews. 34 pages. Full-resolution version available at http://www.astron.nl/~oosterlo/accretionRevie