Matrix geometries and Matrix Models

We study a two parameter single trace 3-matrix model with SO(3) global symmetry. The model has two phases, a fuzzy sphere phase and a matrix phase. Configurations in the matrix phase are consistent with fluctuations around a background of commuting matrices whose eigenvalues are confined to the interior of a ball of radius R=2.0. We study the co-existence curve of the model and find evidence that it has two distinct portions one with a discontinuous internal energy yet critical fluctuations of the specific heat but only on the low temperature side of the transition and the other portion has a continuous internal energy with a discontinuous specific heat of finite jump. We study in detail the eigenvalue distributions of different observables.Comment: 20 page

The Ontology for Biomedical Investigations

The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource (http://obi-ontology.org) providing details on the people, policies, and issues being addressed in association with OBI. The current release of OBI is available at http://purl.obolibrary.org/obo/obi.owl

Energy-Efficienct Mine Ventilation Practices

Energy efficiency in mine ventilation, which is responsible for a substantial amount of total energy consumption, is of paramount concern in underground mining. Achieving energy-efficient mine ventilation practices is not only important for reducing total operating and energy costs but is also potentially the most effective means of reducing greenhouse gas emissions and environmental and occupational health and safety. This chapter presents a comprehensive review of the literature on energy-efficient mine ventilation practices and approaches to provide the current knowledge and research frontiers on energy efficiency in mine ventilation. Successful case studies, which resulted in efficiency increases, are also included to illustrate already existing energy efficiency alternatives and energy-saving opportunities. This review is expected to provide mining professionals a tool for improving current operations and achieving best practices

Energy-Efficienct Mine Ventilation Practices

his book presents a state-of-the-art analysis of energy efficiency as applied to mining processes. From ground fragmentation to mineral processing and extractive metallurgy, experts discuss the current state of knowledge and the nagging questions that call for further research. It offers an excellent resource for all mine managers and engineers who want to improve energy efficiency to boost both production efficiency and sustainability. It will also benefit graduate students and experienced researchers looking for a comprehensive review of the current state of knowledge concerning energy efficiency in the minerals industry

Random Excitation of Bistable Harvesters

This chapter considers nonlinear piezoelastic energy harvesters driven by stationary random noise. A range of devices that exhibit nonlinear dynamics have been proposed, and their response to sinusoidal excitation is often complex, with coexisting periodic solutions or even chaotic solutions. The response of nonlinear harvesters to random noise depends on the statistics of the excitation; the maximum response can occur at particular excitation variances, and this is called stochastic resonance. The stochastic linearisation method is proposed for the optimal design of bistable harvesters subjected to random excitation

Breast- and Salivary Gland-Derived Adenoid Cystic Carcinomas: Potential Post-Transcriptional Divergencies. A Pilot Study Based on miRNA Expression Profiling of Four Cases and Review of the Potential Relevance of the Findings

Adenoid cystic carcinoma (ACC) is a malignant tumor of the salivary glands but identical tumors can also arise from the breast. Despite their similar histomorphological appearance the salivary gland- and the breast-derived forms differ in their clinical features: while ACC of the salivary glands (sACC) have an agressive clinical course, the breast-derived form (bACC) shows a very favourable clinical outcome. To date no exact molecular alterations have yet been identified which would explain the diverse clinical features of the ACCs of different origin. In our pilot experiment we investigated the post-transcriptional features of ACC cases by performing microRNA-profiling on 2-2 bACC and sACC tissues and on 1-1 normal breast and salivary gland tissue. By comparing the microRNA-profiles of the investigated samples we identified microRNAs which were expressed differently in bACC and sACC cases according to their normal controls: 7 microRNAs were overexpressed in sACC cases and downexpressed in bACC tumors (let-7b, let-7c, miR-17, miR-20a, miR-24, miR-195, miR-768-3) while 9 microRNAs were downexpressed in sACC cases and overexpressed in bACC tissues (let-7e, miR-23b, miR-27b, miR-193b, miR-320a, miR-320c, miR-768-5p, miR-1280 and miR-1826) relative to their controls. We also identified 8 microRNAs which were only expressed in sACCs and one microRNA (miR-1234) which was only absent in sACC cases. By target predictor online databases potential targets of the these microRNAs were detected to identify genes that may play central role in the diverse cinical outcome of bACC and sACC cases

Dependence on plasma shape and plasma fueling for small edge-localized mode regimes in TCV and ASDEX Upgrade

\u3cp\u3eWithin the EUROfusion MST1 work package, a series of experiments has been conducted on AUG and TCV devices to disentangle the role of plasma fueling and plasma shape for the onset of small ELM regimes. On both devices, small ELM regimes with high confinement are achieved if and only if two conditions are fulfilled at the same time. Firstly, the plasma density at the separatrix must be large enough (n\u3csub\u3ee,sep\u3c/sub\u3e/n\u3csub\u3eG\u3c/sub\u3e ∼ 0.3), leading to a pressure profile flattening at the separatrix, which stabilizes type-I ELMs. Secondly, the magnetic configuration has to be close to a double null (DN), leading to a reduction of the magnetic shear in the extreme vicinity of the separatrix. As a consequence, its stabilizing effect on ballooning modes is weakened.\u3c/p\u3