Motion Sickness Lessons from the Southern Ocean

BACKGROUND: The objectives were to assess the prevalence, severity, and medication taken, and to look for predictive factors, in order to better identify characteristics of passengers at risk of motion sickness during transport from Hobart in Tasmania to the French polar stations in Antarctica. METHODS: There were 239 passengers who were surveyed over 4 yr with 4 round trips per year using the Motion Sickness Susceptibility Questionnaire (MSSQ), Simulator Sickness Questionnaire (SSQ), state-trait anxiety test (STAI -Trait and STAI -State), and general parameters (age, gender, number of trips, jet-lag, direction of the trip), medication, calculation of the distance of each passenger’s cabin to the Centre of Gravity (CoG.). RESULTS: While the passengers had a low intrinsic sensitivity to motion sickness (MSSQ), 94% reported at least one SSQ symptom of motion sickness, and 38% vomited. Five associated factors were discovered: greater initial sensitivity (MSSQ), anticipation of being ill, younger age, higher level of anxiety at midtrip, and greater distance from the CoG. Of the passengers, there were 54% who took anti-motion sickness medication at different times of the trip, however, these passengers experienced more nausea. This could be due to self-selection since they were more sensitive to motion sickness. CONCLUSION: We identified three predictive factors of motion sickness (greater intrinsic susceptibility, younger age, and greater cabin distance from the CoG). For preventive purposes, two associated factors of MS (anticipation of being ill, MSSQ score) were determined to classify three groups of risk of MS to improve passenger care during the trip

Synthèse de modèles régionaux d'estimation de crue utilisée en France et au Québec

De nombreuses méthodes régionales ont été développées pour améliorer l'estimation de la distribution des débits de crues en des sites où l'on dispose de peu d'information ou même d'aucune information. Cet article présente une synthèse de modèles hydrologiques utilisés en France et au Québec (Canada), à l'occasion d'un séminaire relatif aux " méthodes d'estimation régionale en hydrologie " tenu à Lyon en mai 1997. Les modèles français sont fortement liés à une technique d'extrapolation de la distribution des crues, la méthode du Gradex, qui repose sur l'exploitation probabiliste conjointe des séries hydrométriques et pluviométriques. Ceci explique les deux principaux volets d'études régionales pratiquées en France : les travaux liés à la régionalisation des pluies et ceux liés à la régionalisation des débits. Les modèles québecois comprennent généralement deux étapes : la définition et la détermination de régions hydrologiquement homogènes, puis l'estimation régionale, par le transfert à l'intérieur d'une même région de l'information des sites jaugés à un site non-jaugé ou partiellement jaugé pour lequel on ne dispose pas d'information suffisante. Après avoir donné un aperçu des méthodes pratiquées dans les deux pays, une discussion dégage les caractéristiques principales et les complémentarités des différentes approches et met en évidence l'intérêt de développer une collaboration plus étroite pour mieux tenir compte des particularités et des complémentarités des méthodes développées de part et d'autre. Une des pistes évoquées consiste à combiner l'information régionale pluviométrique (approche française) et hydrométrique (approche québécoise).Design flood estimates at ungauged sites or at gauged sites with short records can be obtained through regionalization techniques. Various methods have been employed in different parts of the world for the regional analysis of extreme hydrological events. These regionalization approaches make different assumptions and hypotheses concerning the hydrological phenomena being modeled, rely on various types of continuous and non-continuous data, and often fall under completely different theories. A research seminar dealing with " regional estimation methods in hydrology " took place in Lyon during the month of May 1997, and brought together various researchers and practitioners mainly from France and the Province of Quebec (Canada). The present paper is based on the conferences and discussions that took place during this seminar and aims to review, classify, comparatively evaluate, and potentially propose improvements to the most prominent regionalization techniques utilized in France and Quebec. The specific objectives of this paper are :· to review the main regional hydrologic models that have been proposed and commonly used during the last three decades ;· to classify the literature into different groups according to the origin of the method, its specific objective, and the technique it adopts ; · to present a comprehensive evaluation of the characteristics of the methods, and to point out the hypotheses, data requirements, strengths and weaknesses of each particular one ; and · to investigate and identify potential improvements to the reviewed methods, by combining and extending the various approaches and integrating their particular strengths.Regionalization approaches adopted in France include the Gradex method which represents a simplified rainfall-runoff model which provides estimates of flood magnitudes of given probabilities and is based on rainfall data which often cover longer periods and are more reliable than flow data (Guillot and Duband, 1967 ; CFGB, 1994). It is based on the hypotheses that beyond a given rainfall threshold (known as the pivot point), all water is transformed into runoff, and that a rainfall event of a given duration generates runoff for the same length of time. These hypotheses are equivalent to assuming that, beyond the pivot point, the rainfall-runoff relationship is linear and that the precipitation and runoff probability curves are parallel on a Gumbel plot.In Quebec (and generally in North America), regional flood frequency analysis involves usually two steps : delineation of homogeneous regions, and regional estimation. In the first step, the focus is on identifying and regrouping sites which seem sufficiently homogeneous or sufficiently similar to the target ungauged site to provide a basis for information transfer. The second step of the analysis consists in inferring flood information (such as quantiles) at the target site using data from the stations identified in the first step of the analysis. Two types of " homogeneous " regions can be proposed : fixed set regions (geographically contiguous or non-contiguous) and neighborhood type of regions. The second type includes the methods of canonical correlation analysis and of the regions of influence. Regional estimation can be accomplished using one of two main approaches : index flood or quantile regression methods.The results of this work indicate that the philosophies of regionalization and the methods utilized in France and Quebec are complementary to each other and are based on different needs and outlooks. While the approaches followed in France are characterized by strong conceptual and geographic aspects with an emphasis on the utilization of information related to other phenomena (such as precipitations), the approaches adopted in Quebec rely on the strength of their statistical and stochastic components and usually condense the spatial and temporal information to a realistic functional form. This dissimilarity in the approaches being followed on either side may be originated by the distinct topographic and climatic characteristics of each region (France and Quebec) and by the differences in basin sizes and hydrometeorologic network densities. The conclusions of the seminar point to the large potential of improvements in regional estimation methods, which may result from an enhanced exchange between scientists from both sides : indeed, there is much to gain from learning about the dissimilarities between the various approaches, comparing their performances, and devising new methods that combine their individual strengths. Hence, the Gradex method for example could benefit from an increased utilization of regional flood information, while flood regionalization methods utilized in Quebec could gain much from the formalization of the use of rainfall information and from the integration of an improved modeling of physical hydrologic phenomena. This should result in the enhancement of the efficiency of regional estimation methods and their ability to handle various practical conditions.It is hoped that this research will contribute towards closing the gap between French and Quebec literature, and more generally between the European and the North American hydrological schools of thought, by narrowing the large literature that is available, by providing the necessary cross-evaluation of regional flood analysis models, and by providing comprehensive propositions for improved approaches for regional hydrologic modeling

Investigation on gas-liquid two-phase flow centrifugal pump performances for different rotational speeds

International audiencePerformance characteristics of a centrifugal pump under gas-liquid mixture are presented, using a direct coupled single-stage, single-suction centrifugal pump. Both experimental and numerical simulations comparison are carried out, for three different rotational speeds and different inlet gas volume fractions, the results of which are presented, based on dimensionless coefficients from similarity laws. The numerical results show that good agreement is obtained with experimental data at nominal rotational speed for several flow coefficients. It is found that the running of the pump is near the sudden break down of the present pump when the inlet void fraction is below 7%. However, numerical results are less sensitive to rotational speed effects compared with experiment ones; the influence of decreasing rotational speed on pump performances is more and more pronounced when inlet gas void fraction increases and flow coefficient decreases. Froude number effects are taken into account in order to explain part of these differences

Determining the probability of cyanobacterial blooms: the application of Bayesian networks in multiple lake systems

A Bayesian network model was developed to assess the combined influence of nutrient conditions and climate on the occurrence of cyanobacterial blooms within lakes of diverse hydrology and nutrient supply. Physicochemical, biological, and meteorological observations were collated from 20 lakes located at different latitudes and characterized by a range of sizes and trophic states. Using these data, we built a Bayesian network to (1) analyze the sensitivity of cyanobacterial bloom development to different environmental factors and (2) determine the probability that cyanobacterial blooms would occur. Blooms were classified in three categories of hazard (low, moderate, and high) based on cell abundances. The most important factors determining cyanobacterial bloom occurrence were water temperature, nutrient availability, and the ratio of mixing depth to euphotic depth. The probability of cyanobacterial blooms was evaluated under different combinations of total phosphorus and water temperature. The Bayesian network was then applied to quantify the probability of blooms under a future climate warming scenario. The probability of the "high hazardous" category of cyanobacterial blooms increased 5% in response to either an increase in water temperature of 0.8°C (initial water temperature above 24°C) or an increase in total phosphorus from 0.01 mg/L to 0.02 mg/L. Mesotrophic lakes were particularly vulnerable to warming. Reducing nutrient concentrations counteracts the increased cyanobacterial risk associated with higher temperatures

Generators of simple Lie algebras in arbitrary characteristics

In this paper we study the minimal number of generators for simple Lie algebras in characteristic 0 or p > 3. We show that any such algebra can be generated by 2 elements. We also examine the 'one and a half generation' property, i.e. when every non-zero element can be completed to a generating pair. We show that classical simple algebras have this property, and that the only simple Cartan type algebras of type W which have this property are the Zassenhaus algebras.Comment: 26 pages, final version, to appear in Math. Z. Main improvements and corrections in Section 4.

Differential Forms on Log Canonical Spaces

The present paper is concerned with differential forms on log canonical varieties. It is shown that any p-form defined on the smooth locus of a variety with canonical or klt singularities extends regularly to any resolution of singularities. In fact, a much more general theorem for log canonical pairs is established. The proof relies on vanishing theorems for log canonical varieties and on methods of the minimal model program. In addition, a theory of differential forms on dlt pairs is developed. It is shown that many of the fundamental theorems and techniques known for sheaves of logarithmic differentials on smooth varieties also hold in the dlt setting. Immediate applications include the existence of a pull-back map for reflexive differentials, generalisations of Bogomolov-Sommese type vanishing results, and a positive answer to the Lipman-Zariski conjecture for klt spaces.Comment: 72 pages, 6 figures. A shortened version of this paper has appeared in Publications math\'ematiques de l'IH\'ES. The final publication is available at http://www.springerlink.co

Surgery in recurrent ovarian cancer

Ovarian cancer is one of the most challenging diseases in gynecologic oncology. The presentation of frequent recurrences requires the establishment and further development of therapy standards for this patient group. Surgery is crucial in the therapy of patients with primary ovarian cancer, and the postoperative residual tumor mass is the most relevant clinical prognostic factor. The surgical management of recurrent disease is still subject to an emotional international discussion. Only a few prospective clinical trials focused on the effects of surgery in relapsed ovarian cancer have been published. The available data show improvements in the prognosis due to complete cytoreduction in the setting of recurrence. However, the selection of eligible patients is the essential issue. Therefore, the establishment of reliable predictive factors for complete tumor resection as well as a definition of the group of patients who might profit from this approach remains a field for research. Further randomized trials designed to develop and incorporate operative standards for recurrent ovarian cancer should follow