82 research outputs found

    Healthy axis: Towards an integrated view of the gut-brain health

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    Model-Based Fault Detection and Estimation for Linear Time Invariant and Piecewise Affine Systems by Using Quadratic Boundedness

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    Quadratic boundedness is a notion of stability that is adopted to investigate the design of observers for dynamic systems subject to bounded disturbances. We will show how to exploit such observers for the purpose of fault detection. Toward this end, first of all we present the naive application of quadratic boundedness to construct state observers for linear time-invariant systems with state augmentation, i.e., where additional variables may be introduced to account for the occurrence of a fault. Then a Luenberger observer is designed to estimate the augmented state variable of the system in such a way to detect the fault by using a convenient threshold selection. Finally, such an approach is extended to piecewise affine systems by presenting a hybrid Luenberger observer and its related design based on quadratic boundedness. The design of all the observers for both linear time-invariant and piecewise affine systems can be done by using linear matrix inequalities. Simulation results are provided to show the effectiveness of the proposed approach

    A Distributed Approach for the Detection of Covert Attacks in Interconnected Systems with Stochastic Uncertainties

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    The design of a distributed architecture for the detection of covert attacks in interconnected Cyber-Physical Systems is addressed in this paper, in the presence of stochastic uncertainties. By exploiting communication between neighbors, the proposed scheme allows for the detection of covert attacks that are locally stealthy. The proposed methodology adopts a decentralized filter, jointly estimating the local state and the aggregate effect of the physical interconnections, and uses the communicated estimates to obtain an attack-sensitive residual. We derive some theoretical detection properties for the proposed architecture, and present numerical simulations

    The Cochrane Case: An Epistemic Analysis on Decision-Making and Trust in Science in the Age of Information

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    none4noIn this study we analyze a recent controversy within the biomedical world, concerning the evaluation of safety of certain vaccines. This specific struggle took place among experts: the Danish epidemiologist Peter Gøtzsche on one side and a respected scientific institution, the Cochrane, on the other. However, given its relevance, the consequences of such a conflict invest a much larger spectrum of actors, last but not least the public itself. Our work is aimed at dissecting a specific aspect happening in this complex scenario: strategy. In other words, we want to highlight the value and the impact of strategic decisions when complex issues, as those analyzed, are at stake. In order to address this we have decided to adopt a game-theoretic approach. Our work will be structured as it follows. First, we will introduce the controversy and the two main actors: Peter Gøtzsche and the Cochrane. Second, we will explain why this controversy is important and its value beyond its academic relevance. Third, we will frame the controversy as a game and will provide several models representing different situations, also furnishing an analysis of these distinct scenarios. In the end we will argue why such game-theoretic approach can be useful in dissecting this type of issues.openBoem F.; Bonzio S.; Osimani B.; Sacco A.Boem, F.; Bonzio, S.; Osimani, B.; Sacco, A

    Nonlinear simulation of masonry vaults under earthquake loading

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    Masonry vaults are present in a large number of historical structures and often used as floor-ing and roofing systems in monumental palaces and religious buildings, typically incorporat-ing no backfill. Many of these structures are located in seismic regions and have been shownto be particularly vulnerable during recent earthquakes, with a need for accurate modelling to avoid future losses. Masonry vaults are often analysed using limit analysis procedures un-der the hypotheses of no-tension material and absence of sliding along the masonry joints.However, this method can be inaccurate for barrel vaults found in buildings, which are typi-cally slender with no backfill. In this case, the masonry tensile strength and the progressive damage propagation play an important role in the nonlinear behaviour and ultimate strength of the vault. In this study, a detailed mesoscale finite element mesoscale approach is used to model slender unreinforced barrel vaults subjected to cyclic quasi-static and dynamic load-ing. According to this approach, 3D solid elements connected by 2D damage-plasticity inter-faces are used to represent the arrangement of bricks and mortar present in the masonry. Theproposed numerical description is first validated against the results from physical tests on a barrel vault under quasi-static cyclic loading. Subsequently, the shear response of a prototype vault is analysed by performing nonlinear simulations under prescribed horizontal displace-ments at the supports, considering also the influence of previous damage induced by earth-quakes with different magnitudes

    Distribuição e estratificação vertical do carbono e nitrogênio em solos sob diferentes manejos na região do Pampa Argentino

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    1985-1994One of the expected benefits of no-tillage systems is a higher rate of soil C sequestration. However, higher C retention in soil is not always apparent when notillage is applied, due e.g., to substantial differences in soil type and initial C content. The main purpose of this study was to evaluate the potential of no-tillage management to increase the stock of total organic C in soils of the Pampas region in Argentina. Forty crop fields under no-tillage and conventional tillage systems and seven undisturbed soils were sampled. Total organic C, total N, their fractions and stratification ratios and the C storage capacity of the soils under different managements were assessed in samples to a depth of 30 cm, in three layers (0-5, 5-15 and 15-30 cm). The differences between the C pools of the undisturbed and cultivated soils were significant (p less than 0.05) and most pronounced in the top (0-5 cm) soil layer, with more active C near the soil surface (undisturbed greater than no-tillage greater than conventional tillage). Based on the stratification ratio of the labile C pool (0-5/5-15 cm), the untilled were separated from conventionally tilled areas. Much of the variation in potentially mineralizable C was explained by this active C fraction (R 2 = 0.61) and by total organic C (R 2 = 0.67). No-till soils did not accumulate more organic C than conventionally tilled soils in the 0-30 cm layer, but there was substantial stratification of total and active C pools at no till sites. If the C stratification ratio is really an indicator of soil quality, then the C storage potential of no-tillage would be greater than in conventional tillage, at least in the surface layers. Particulate organic C and potentially mineralizable C may be useful to evaluate variations in topsoil organic matter

    Fault diagnosis for uncertain networked systems

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    Fault diagnosis has been at the forefront of technological developments for several decades. Recent advances in many engineering fields have led to the networked interconnection of various systems. The increased complexity of modern systems leads to a larger number of sources of uncertainty which must be taken into consideration and addressed properly in the design of monitoring and fault diagnosis architectures. This chapter reviews a model-based distributed fault diagnosis approach for uncertain nonlinear large-scale networked systems to specifically address: (a) the presence of measurement noise by devising a filtering scheme for dampening the effect of noise; (b) the modeling of uncertainty by developing an adaptive learning scheme; (c) the uncertainty issues emerging when considering networked systems such as the presence of delays and packet dropouts in the communication networks. The proposed architecture considers in an integrated way the various components of complex distributed systems such as the physical environment, the sensor level, the fault diagnosers, and the communication networks. Finally, some actions taken after the detection of a fault, such as the identification of the fault location and its magnitude or the learning of the fault function, are illustrated

    Phronesis and Automated Science: The Case of Machine Learning and Biology

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    The applications of machine learning (ML) and deep learning to the natural sciences has fostered the idea that the automated nature of algorithmic analysis will gradually dispense human beings from scientific work. In this paper, I will show that this view is problematic, at least when ML is applied to biology. In particular, I will claim that ML is not independent of human beings and cannot form the basis of automated science. Computer scientists conceive their work as being a case of Aristotle’s poiesis perfected by techne, which can be reduced to a number of straightforward rules and technical knowledge. I will show a number of concrete cases where at each level of computational analysis, more is required to ML than just poiesis and techne, and that the work of ML practitioners in biology needs also the cultivation of something analogous to phronesis, which cannot be automated. But even if we knew how to frame phronesis into rules (which is inconsistent with its own definition), still this virtue is deeply entrenched in our biological constitution, which computers lack. Whether computers can fully perform scientific practice (which is the result of the way we are cognitively and biologically) independently of humans (and their cognitive and biological specificities) is an ill-posed question
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