Probing the imprint of interacting dark energy on very large scales

The observed galaxy power spectrum acquires relativistic corrections from light-cone effects, and these corrections grow on very large scales. Future galaxy surveys in optical, infrared and radio bands will probe increasingly large wavelength modes and reach higher redshifts. In order to exploit the new data on large scales, an accurate analysis requires inclusion of the relativistic effects. This is especially the case for primordial non-Gaussianity and for extending tests of dark energy models to horizon scales. Here we investigate the latter, focusing on models where the dark energy interacts nongravitationally with dark matter. Interaction in the dark sector can also lead to large-scale deviations in the power spectrum. If the relativistic effects are ignored, the imprint of interacting dark energy will be incorrectly identified and thus lead to a bias in constraints on interacting dark energy on very large scales.Web of Scienc

Detection of Parietaria Mottle Virus by RT-qPCR: An Emerging Virus Native of Mediterranean Area That Undermine Tomato and Pepper Production in Southern Italy

Parietaria mottle virus (PMoV) is considered an emerging virus in many countries of the Mediterranean basin, especially on tomato and pepper crops. Symptoms on tomato leaves and fruits can be easily confused with those induced by cucumber mosaic virus (CMV) with necrogenic satellite RNA (CMV-satRNA), tomato spotted wilt virus (TSWV) or tomato mosaic virus (ToMV). Mixed infection of these viruses has been also reported in some tomato cultivars, with an increase in the complexity of the symptoms and severity of the disease. Although a specific serum and riboprobes have been produced, nowadays no sensitive diagnostic methods are available for the rapid PMoV detection. Here, we have developed a RT-qPCR assay with the aim to establish a more sensitive and specific method for PMoV detection. Specific primers and TaqMan probe were designed and in silico tested with all PMoV isolates available in GenBank. Moreover, this method was evaluated on tomato naturally infected samples from Sicily region (Italy). Results obtained showed that the RT-qPCR assay developed in this work is extremely sensitive, in fact, it is able to detect as few as 10 PMoV RNA copies in tomato total RNA; moreover, it will be a particularly valuable tool for early detection of PMoV. Furthermore, the analyzes on field samples show how this pathogen is increasingly present in tomato crops in the last years, helping to undermine the Italian horticultural sector

Unified Dark Matter models with fast transition

We investigate the general properties of Unified Dark Matter (UDM) fluid models where the pressure and the energy density are linked by a barotropic equation of state (EoS) $p = p(\rho)$ and the perturbations are adiabatic. The EoS is assumed to admit a future attractor that acts as an effective cosmological constant, while asymptotically in the past the pressure is negligible. UDM models of the dark sector are appealing because they evade the so-called "coincidence problem" and "predict" what can be interpreted as $w_{\rm DE} \approx -1$, but in general suffer the effects of a non-negligible Jeans scale that wreak havoc in the evolution of perturbations, causing a large Integrated Sachs-Wolfe effect and/or changing structure formation at small scales. Typically, observational constraints are violated, unless the parameters of the UDM model are tuned to make it indistinguishable from $\Lambda$CDM. Here we show how this problem can be avoided, studying in detail the functional form of the Jeans scale in adiabatic UDM perturbations and introducing a class of models with a fast transition between an early Einstein-de Sitter CDM-like era and a later $\Lambda$CDM-like phase. If the transition is fast enough, these models may exhibit satisfactory structure formation and CMB fluctuations. To consider a concrete case, we introduce a toy UDM model and show that it can predict CMB and matter power spectra that are in agreement with observations for a wide range of parameter values.Comment: 30 pages, 15 figures, JHEP3 style, typos corrected; it matches the published versio

Evaluation of FHIT gene alterations in ovarian cancer.

The FHIT gene, recently cloned and mapped on chromosome 3p14.2, has frequently been found to be abnormal in several established cancer cell lines and primary tumours. As alterations of chromosome 3p are common events in ovarian cancers with breakpoint sites at 3p14.2, we decided to investigate the role of FHIT in human ovarian tumorigenesis. Fifty-four primary ovarian carcinomas were studied by reverse transcription of FHIT mRNA followed by polymerase chain reaction (PCR) amplification and sequencing of products. The same tumours and matched normal tissues were also investigated for loss of heterozygosity using three microsatellite markers located inside the gene. We found an abnormal transcript of the FHIT gene in two cases (4%) and allelic losses in eight cases (15%). Twelve (22%) of the 54 tumours investigated belonged to young patients with a family history of breast/ovarian cancer. In none of these cases was the FHITgene found to be altered. Our results indicate that FHITplays a role in a small proportion of ovarian carcinomas

Characterizing the cosmological gravitational wave background: Anisotropies and non-Gaussianity

A future detection of the stochastic gravitational wave background (SGWB) with gravitational wave (GW) experiments is expected to open a new window on early universe cosmology and on the astrophysics of compact objects. In this paper we study SGWB anisotropies, that can offer new tools to discriminate between different sources of GWs. In particular, the cosmological SGWB inherits its anisotropies both (i) at its production and (ii) during its propagation through our perturbed universe. Concerning (i), we show that it typically leads to anisotropies with order one dependence on frequency. We then compute the effect of (ii) through a Boltzmann approach, including contributions of both large-scale scalar and tensor linearized perturbations. We also compute for the first time the three-point function of the SGWB energy density, which can allow one to extract information on GW non-Gaussianity with interferometers. Finally, we include nonlinear effects associated with long wavelength scalar fluctuations, and compute the squeezed limit of the 3-point function for the SGWB density contrast. Such limit satisfies a consistency relation, conceptually similar to that found in the literature for the case of cosmic microwave background perturbations

Nonlinear relativistic corrections to cosmological distances, redshift and gravitational lensing magnification. I - Key results

The next generation of telescopes will usher in an era of precision cosmology, capable of determining the cosmological model to beyond the percent level. For this to be effective, the theoretical model must be understood to at least the same level of precision. A range of subtle relativistic effects remain to be explored theoretically, and offer the potential for probing general relativity in this new regime. We present the distance-redshift relation to second order in cosmological perturbation theory for a general dark energy model. This relation determines the magnification of sources at high precision, as well as redshift space distortions in the mildly non-linear regime. We identify a range of new lensing effects, including: double-integrated and nonlinear integrated Sach-Wolfe contributions, transverse Doppler effects, lensing from the induced vector mode and gravitational wave backgrounds, in addition to lensing from the second-order potential. Modifications to Doppler lensing from redshift-space distortions are identified. Finally, we find a new double-coupling between the density fluctuations integrated along the line of sight, and gradients in the density fluctuations coupled to transverse velocities along the line of sight. These can be large and thus offer important new probes of gravitational lensing and general relativity. This paper accompanies arXiv:1402.1933, where a comprehensive derivation is given.Comment: 7 pages. v2 has significant presentational changes. v3 has new discussion on the magnitude of the corrections, plus minor corrections, and is the version to appear in CQ

Anisotropies and non-Gaussianity of the cosmological gravitational wave background

The stochastic gravitational wave background (SGWB) is expected to be a key observable for gravitational wave (GW) interferometry. Its detection will open a new window to early Universe cosmology and to the astrophysics of compact objects. Using a Boltzmann approach, we study the angular anisotropies of the GW energy density, which is an important tool to disentangle the different cosmological and astrophysical contributions to the SGWB. Anisotropies in the cosmological background are imprinted both at its production and by GW propagation through the large-scale scalar and tensor perturbations of the Universe. The first contribution is not present in the cosmic microwave background radiation (as the Universe is not transparent to photons before recombination), causing an order 1 dependence of the anisotropies on frequency. Moreover, we provide a new method to characterize the cosmological SGWB through its possible deviation from Gaussian statistics. In particular, the SGWB will become a new probe of the primordial non-Gaussianity of the large-scale cosmological perturbations

Gravitational wave anisotropies from primordial black holes

An observable stochastic background of gravitational waves is generated whenever primordial black holes are created in the early universe thanks to a small-scale enhancement of the curvature perturbation. We calculate the anisotropies and non-Gaussianity of such stochastic gravitational waves background which receive two contributions, the first at formation time and the second due to propagation effects. The former contribution can be generated if the distribution of the curvature perturbation is characterized by a local and scale-invariant shape of non-Gaussianity. Under such an assumption, we conclude that a sizeable magnitude of anisotropy and non-Gaussianity in the gravitational waves would suggest that primordial black holes may not comply the totality of the dark matter.An observable stochastic background of gravitational waves is generated whenever primordial black holes are created in the early universe thanks to a small-scale enhancement of the curvature perturbation. We calculate the anisotropies and non-Gaussianity of such stochastic gravitational waves background which receive two contributions, the first at formation time and the second due to propagation effects. The former contribution can be generated if the distribution of the curvature perturbation is characterized by a local and scale-invariant shape of non-Gaussianity. Under such an assumption, we conclude that a sizeable magnitude of anisotropy and non-Gaussianity in the gravitational waves would suggest that primordial black holes may not comply the totality of the dark matter

Genetic structure and molecular variability of grapevine fanleaf virus in sicily

Grapevine fanleaf virus (GFLV) is one of the main causes of grapevine fanleaf degeneration disease (GFDD) and is present in almost all areas where grapevine is cultivated. In this work, we ascertained the presence and spread of GFLV in different commercial vineyards in four Sicilian provinces (Italy), and its genetic structure and molecular variability were studied. In detail, a total of 617 grapevine samples of 11 autochthonous grapevine cultivars were collected in 20 commercial vineyards. Preliminary screening by serological (DAS-ELISA) and molecular (RT-PCR) analyses for ArMV (arabis mosaic virus) and GFLV detection were conducted. Results obtained showed the absence of ArMV in all the samples analyzed, while 48 out of 617 samples gave positive results to GFLV, for a total of 9 out of 11 cultivars analyzed. Phylogenetic analyses carried out on the GFLV-CP gene of 18 Sicilian GFLV sequences selected in this study showed a certain degree of variability among the Sicilian isolates, suggesting a different origin, probably as a consequence of the continuous interchange of GFLV-infected propagating material with other Italian regions or viticultural areas located in other countries

A review of the most common and economically important diseases that undermine the cultivation of tomato crop in the mediterranean basin

Tomato (Solanum lycopersicum L.), family Solanaceae, has become in the past fifty years one of the most important and extensively grown horticultural crops in the Mediterranean region and throughout the world. In 2019, more than 180 million tonnes of tomato have been produced worldwide, out of which around 42 million tonnes in Mediterranean countries. Due to its genetic properties, tomato is afflicted by numerous plant diseases induced by fungal, bacterial, phytoplasma, virus, and viroid pathogens. Not only is its genetic inheritance of great importance to the management of the numerous tomato pathogens, but equally as important are also the present climate changes, the recently revised phytopathological control measures, and the globalization of the seed industry. Thus, the recognition of symptoms and the knowledge of the distribution and spread of the disease and of the methods for early detection of the pathogens are the major prerequisites for a successful management of the disease. In this review, we will describe the main tomato pathogens in the Mediterranean area that impact mostly the tomato yield and provide the current and perspective measures necessary for their successful management