Emergence of Hierarchy on a Network of Complementary Agents

Complementarity is one of the main features underlying the interactions in biological and biochemical systems. Inspired by those systems we propose a model for the dynamical evolution of a system composed by agents that interact due to their complementary attributes rather than their similarities. Each agent is represented by a bit-string and has an activity associated to it; the coupling among complementary peers depends on their activity. The connectivity of the system changes in time respecting the constraint of complementarity. We observe the formation of a network of active agents whose stability depends on the rate at which activity diffuses in the system. The model exhibits a non-equilibrium phase transition between the ordered phase, where a stable network is generated, and a disordered phase characterized by the absence of correlation among the agents. The ordered phase exhibits multi-modal distributions of connectivity and activity, indicating a hierarchy of interaction among different populations characterized by different degrees of activity. This model may be used to study the hierarchy observed in social organizations as well as in business and other networks.Comment: 13 pages, 4 figures, submitte

Characterizing neuromorphologic alterations with additive shape functionals

The complexity of a neuronal cell shape is known to be related to its function. Specifically, among other indicators, a decreased complexity in the dendritic trees of cortical pyramidal neurons has been associated with mental retardation. In this paper we develop a procedure to address the characterization of morphological changes induced in cultured neurons by over-expressing a gene involved in mental retardation. Measures associated with the multiscale connectivity, an additive image functional, are found to give a reasonable separation criterion between two categories of cells. One category consists of a control group and two transfected groups of neurons, and the other, a class of cat ganglionary cells. The reported framework also identified a trend towards lower complexity in one of the transfected groups. Such results establish the suggested measures as an effective descriptors of cell shape

The Portuguese Formal Social Support for Autonomy and Dependence in Pain Inventory (FSSADI_PAIN): A preliminary validation study.

WOS:000326693900009 (Nº de Acesso Web of Science)Objectives. Development and preliminary validation of a Portuguese measure of perceived Formal Social Support for Autonomy and Dependence in Pain (FSSADI_PAIN). Methods. One hundred and fifty-one older adults (88.1% women), between 56 and 94 years of age (M = 75.41; SD = 9.11), who attended one of the following institutions – day care centre (33.1%), nursing home (36.4%) and senior university (30.5%) – were recruited for this study. Along with the FSSADI_PAIN, participants filled out the Portuguese versions of the Brief Pain Inventory (Azevedo et al., 2007, Dor, 15, 6) and the Social Support Scale of Medical Outcomes Survey (Pais-Ribeiro & Ponte, 2009, Psicologia, Saude & Doença, 10, 163). Results. The factorial structure reflected the functions of perceived promotion of (1) dependence and (2) autonomy, showing good internal consistency (a > .70) and sensitivity indices. The FSSADI_PAIN showed good content, discriminant and criterion validity; it differentiated the perceptions of promotion of dependence/autonomy according to individual’s pain severity and disability, as well as the type of institution. Conclusions. These preliminary findings suggest that the FSSADI_PAIN is an innovative and promising measure of perceived formal social support adapted to pain-related context

Survival-extinction phase transition in a bit-string population with mutation

A bit-string model for the evolution of a population of haploid organisms, subject to competition, reproduction with mutation and selection is studied, using mean field theory and Monte Carlo simulations. We show that, depending on environmental flexibility and genetic variability, the model exhibits a phase transtion between extinction and survival. The mean-field theory describes the infinite-size limit, while simulations are used to study quasi-stationary properties.Comment: 11 pages, 5 figure

Engendering pain management practices: the role of physician sex on chronic low-back pain assessment and treatment prescriptions

The impact of physician sex on dimensions of medical care such as treatment prescriptions and referrals has been underexplored, especially in a pain context. Also, few studies have analyzed whether physician sex moderates the influence of patients' or clinical situations' characteristics on pain management practices or its mediating processes. Therefore, our goal was to explore whether physician sex moderates the effects of patient (distressed) pain behaviors and diagnostic evidence of pathology (EP) on treatment prescriptions and referrals for chronic low-back pain, and to explore the mediating role of pain credibility judgments and psychological attributions on these effects. A total of 310 general practitioners (GPs; 72.6% women) participated in a between-subjects design, 2 (patient pain behaviors) x 2 (EP) x 2 (GP sex) x 2 (patient sex). GPs were presented with vignettes depicting a fe(male) chronic low-back pain patient, with(out) distress and with(out) EP (eg, herniated disc). GPs judged the patient's pain and the probability of treatment prescriptions and referrals. Results showed that EP had a larger effect on male than on female physicians' referrals to psychology/psychiatry. Also, GP sex moderated the pain judgments that accounted for the effect of EP and pain behaviors on prescriptions. These findings suggest framing medical decision-making as a process influenced by gender assumptions.info:eu-repo/semantics/acceptedVersio

Older adults’ preferences for formal social support of autonomy and dependence in pain: development and validation of a scale

Chronic pain among older adults is common and often disabling. Pain-related formal social support (e.g., provided by staff at day-care centres, nursing homes), and the extent to which it promotes functional autonomy or dependence, plays a significant role in the promotion of older adults’ ability to engage in their daily activities. Assessing older adults’ preferences for pain-related social support for functional autonomy or dependence could contribute to increase formal social support responsiveness to individuals’ needs. Therefore, this study aimed at developing and validating the Preferences for Formal Social Support of Autonomy and Dependence in pain Inventory (PFSSADI). One hundred and sixty five older adults with chronic musculoskeletal pain (Mage=79.1, 67.3% women), attending day-care centers, completed the PFSSADI, the revised Formal Social Support for Autonomy and Dependence in Pain Inventory, and a measure of desire for (in)dependence; the PFSSADI was filled out again 6 weeks later. Confirmatory factor analyses showed a structure of two correlated factors (r= .56): (a) Preferences for Autonomy Support (?=.99); and (b) Preferences for Dependence Support (?=.98). The scale showed good test-retest reliability, sensitivity and discriminant and concurrent validity; the higher the preferences for dependence support the higher the desire for dependence (r=.33) and the lower the desire for independence (r=-.41). The PFSSADI is an innovative tool, which may contribute to explore the role of pain-related social support responsiveness on the promotion of older adults’ functional autonomy when in pain.info:eu-repo/semantics/acceptedVersio

Cultural adaptation and psychometric validation of the Portuguese breakthrough pain assessment tool with cancer patients

Breakthrough cancer pain (BTcP) is a transient exacerbation of pain that occurs over persistent, stable, and adequately controlled cancer background pain. It is prevalent and bears severe consequences to patients' quality-of-life. The effective management of BTcP depends on fast and reliable (re)assessment. The Breakthrough pain Assessment Tool (BAT) is one of the most concise and reliable self-report instruments adapted to clinical contexts so far, showing good psychometric qualities in the United Kingdom, the Netherlands, and South Korea. As to promote the effective management of BTcP in Portuguese-speaking communities this study, first aimed to culturally adapt and validate the Portuguese version of the BAT (BAT-Pt). Second, and most importantly, it sought to provide novel evidence on its criterion validity by investigating its association with measures of psychological distress, which has not been yet investigated. The BAT was translated into European Portuguese, using the back-translation method, and culturally adapted. Its psychometric properties (factor structure, internal consistency, construct and criterion validity) were analyzed in a cross-sectional multicenter study, with a sample of 65 cancer patients (49.2% women) recruited from eight hospitals in mainland Portugal (a priori power analysis determined a minimum sample of 50). Health professionals collected patients' clinical information, assessed their functional disability (ECOG Performance Status) and the adequacy of pain control. In addition to the Portuguese version of the BAT (BAT_Pt), patients completed the Portuguese versions of the Brief Pain Inventory, the Hospital Anxiety and Depression Scale, a Distress Thermometer and answered questions about the adequacy of pain control. The BAT-Pt was very well accepted by experts and patients. As hypothesized, a Principal Axis Factor Analysis revealed two underlying factors accounting for 55.2% of the variance: (1) Pain Severity and Impact of BTcP and (2) Duration of BTcP and Medication Inefficacy. Two items (on episode frequency and medication efficacy) were analyzed separately given their lower/cross loadings. The BAT-Pt showed good internal consistency overall (?=0.79) and for each sub-scale, namely, Pain Severity and Impact of BTcP (n=5 items; ?=0.86) and Duration of BTcP and Medication Inefficacy (n=2 items; rsb=0.62).info:eu-repo/semantics/acceptedVersio

The research-teaching nexus from the Portuguese academics’ perspective: a qualitative case study in a school of social sciences and humanities

This paper reports on a study conducted as part of an action-research project—INTEGRA I&E—aiming to promote the research and teaching (R&T) nexus at the School of Social Sciences and Humanities of a Research University in Lisbon, Portugal (Instituto Universitário de Lisboa, ISCTE-IUL). This study set out to investigate a multi-informant perspective of the academics’ rhetoric (conceptions, perception of barriers/facilitators and consequences) concerning the nexus, which can be considered at different levels of the curricular and organizational structure. Focus groups were conducted with 26 professors and 8 researchers from six different disciplinary areas and, afterwards, recorded and transcribed. A content analysis was used to categorize and quantify participants’ responses. Four themes emerged: practices linking R&T, barriers, facilitators and consequences of the nexus. Different levels of analysis were identified for each theme, namely, the level of ISCTE-IUL, Research Centers, Departments, Courses and Classes. Some disciplinary differences were also encountered. This study contributes with a multi-informant and multi-level perspective of academics’ conceptions of the R&T nexus in a Portuguese research-oriented university.info:eu-repo/semantics/acceptedVersio

On the body-mind nexus in chronic musculoskeletal pain: A scoping review

Background and objective: Bodily experience disturbances are frequent among chronic musculoskeletal pain patients and associated with important pain-related psychosocial outcomes (e.g., disability, quality of life). However, the relationship between bodily experience and the psychological dimensions of chronic pain (e.g., affective, cognitive) has only recently garnered attention. This scoping review aimed to identify trends and gaps in research on the nexus between body awareness, body image, and body schema, and psychological processes/outcomes in adults with chronic musculoskeletal pain to inform future directions for research and practice. Databases and data treatment: This study was guided by Arksey and O’Malley's guidelines and PRISMA-ScR recommendations. Keywords related to body awareness/body image/body schema and pain were searched on PsycInfo and PubMed from database inception until 16 February 2021; 2045 articles were screened, and 41 met the inclusion criteria (i.e., primary quantitative studies investigating body awareness/body image/body schema in relation to pain-related psychological outcomes/processes in chronic musculoskeletal pain). Results: The referred bodily experience constructs have been inconsistently defined. Body awareness was the most investigated construct, with consistent operationalization strategies. The links between body schema/body image and pain-related psychological processes/outcomes are still under-investigated. Most studies examined the role of bodily experience as a correlate/predictor of psychological outcomes/processes; overall, a better relationship with one's own body was associated with better pain-related psychological outcomes/processes. Conclusions: Our findings emphasize the relevance of further investigating body-mind relations in musculoskeletal pain and the development of therapies designed to improve the bodily experience within multidisciplinary treatment programmes. Suggestions for future research are discussed. Significance: This scoping review identifies trends/gaps in current research on the relationship between body awareness/body image/body schema and pain-related psychological processes/outcomes in adults with musculoskeletal pain. Overall, findings suggest that better bodily experiences are associated to lower fear-avoidance beliefs, better self-regulation strategies and better chronic pain adjustment, being important targets in pain management interventions. Nonetheless, the results also emphasize the need to further investigate the causal relationships and other outcomes related to psychological resilience, as well as to develop gold standard treatments focused on bodily experience.info:eu-repo/semantics/acceptedVersio