Charge Asymmetry in the Brane World and Formation of Charged Black Holes

In theories with an infinite extra dimension, free particles localized on the brane can leak out to the extra space. We argue that if there were color confinement in the bulk, electrons would be more able to escape than quarks and than protons (which are composed states). Thus, this process generates an electric charge asymmetry on brane matter densities. A primordial charge asymmetry during Big Bang Nucleosynthesis era is predicted. We use current bounds on this and on electron disappearance to constrain the parameter space of these models. Although the generated asymmetry is generically small, it could be particularly enhanced on large densities as in astrophysical objects, like massive stars. We suggest the possibility that such accumulation of charge may be linked, upon supernova collapse, to the formation of a charged Black Hole and the generation of Gamma-Ray Bursts.Comment: Four pages, one figure. Minor changes, conclusions remai

Neutron background in large-scale xenon detectors for dark matter searches

Simulations of the neutron background for future large-scale particle dark matter detectors are presented. Neutrons were generated in rock and detector elements via spontaneous fission and (alpha,n) reactions, and by cosmic-ray muons. The simulation techniques and results are discussed in the context of the expected sensitivity of a generic liquid xenon dark matter detector. Methods of neutron background suppression are investigated. A sensitivity of $10^{-9}-10^{-10}$ pb to WIMP-nucleon interactions can be achieved by a tonne-scale detector.Comment: 35 pages, 13 figures, 2 tables, accepted for publication in Astroparticle Physic

Predicted modulated differential rates for direct WIMP searches at low energy transfers

The differential event rate for direct detection of dark matter, both the time averaged and the modulated one due to the motion of the Earth, are discussed. The calculations focus on relatively light cold dark matter candidates (WIMP) and low energy transfers. It is shown that for sufficiently light WIMPs the extraction of relatively large nucleon cross sections is possible. Furthermore for some WIMP masses the modulation amplitude may change sign, meaning that, in such a case, the maximum rate may occur six months later than naively expected. This effect can be exploited to yield information about the mass of the dark matter candidate, if and when the observation of the modulation of the event rate is established.Comment: 16 pages, 22 figures; references adde

First Results from the Heidelberg Dark Matter Search Experiment

The Heidelberg Dark Matter Search Experiment (HDMS) is a new ionization Germanium experiment in a special design. Two concentric Ge crystals are housed by one cryostat system, the outer detector acting as an effective shield against multiple scattered photons for the inner crystal, which is the actual dark matter target. We present first results after successfully running the prototype detector for a period of about 15 months in the Gran Sasso Underground Laboratory. We analyze the results in terms of limits on WIMP-nucleon cross sections and present the status of the full scale experiment, which will be installed in Gran Sasso in the course of this year.Comment: 11 pages, latex, 4 tables, 10 figures; submitted to Phys. Rev.

Supersymmetric Dark Matter and Yukawa Unification

An analysis of supersymmetric dark matter under the Yukawa unification constraint is given. The analysis utilizes the recently discovered region of the parameter space of models with gaugino mass nonuniversalities where large negative supersymmetric corrections to the b quark mass appear to allow $b-\tau$ unification for a positive $\mu$ sign consistent with the $b\to s+\gamma$ and $g_{\mu}-2$ constraints. In the present analysis we use the revised theoretical determination of $a_{\mu}^{SM}$ ($a_{\mu}= (g_{\mu}-2)/2$) in computing the difference $a_{\mu}^{exp}-a_{\mu}^{SM}$ which takes account of a reevaluation of the light by light contribution which has a positive sign. The analysis shows that the region of the parameter space with nonuniversalities of the gaugino masses which allows for unification of Yukawa couplings also contains regions which allow satisfaction of the relic density constraint. Specifically we find that the lightest neutralino mass consistent with the relic density constraint, $b\tau$ unification for SU(5) and $b-t-\tau$ unification for SO(10) in addition to other constraints lies in the region below 80 GeV. An analysis of the maximum and the minimum neutralino-proton scalar cross section for the allowed parameter space including the effect of a new determination of the pion-nucleon sigma term is also given. It is found that the full parameter space for this class of models can be explored in the next generation of proposed dark matter detectors.Comment: 28 pages,nLatex including 5 fig

Antiprotons in cosmic rays from neutralino annihilation

We calculate the antiproton flux due to relic neutralino annihilations, in a two-dimensional diffusion model compatible with stable and radioactive cosmic ray nuclei. We find that the uncertainty in the primary flux induced by the propagation parameters alone is about two orders of magnitude at low energies, and it is mainly determined by the lack of knowledge on the thickness of the diffusive halo. On the contrary, different dark matter density profiles do not significantly alter the flux: a NFW distribution produces fluxes which are at most 20% higher than an isothermal sphere. The most conservative choice for propagation parameters and dark matter distribution normalization, together with current data on cosmic antiprotons, cannot lead to any definitive constraint on the supersymmetric parameter space, neither in a low-energy effective MSSM, or in a minimal SUGRA scheme. However, if the best choice for propagation parameters - corresponding to a diffusive halo of L=4 kpc - is adopted, some supersymmetric configurations with the neutralino mass of about 100 GeV should be considered as excluded. An enhancement flux factor - due for instance to a clumpy dark halo or to a higher local dark matter density - would imply a more severe cut on the supersymmetric parameters.Comment: 23 pages, 2 tables and 19 figures, typeset with ReVTeX4. The paper may also be found at http://www.to.infn.it/~fornengo/papers/pbar03.ps.gz or through http://www.to.infn.it/astropart/index.html A subsection added. Final version to appear in PR

Preformed and de novo DSA are associated with T-cell-mediated rejection in pediatric liver transplant recipients requiring clinically indicated liver biopsy.

Despite growing interest about the impact of donor-specific HLA antibodies (DSA) in LT limited data are available for pediatric recipients. Our aim was to perform a retrospective single-center chart review of children (0-16 years) having undergone LT between January 1, 2005 and December 31, 2017, to characterize DSA, to identify factors associated with the development of de novo DSA, and to analyze potential associations with the diagnosis of TCMR. Information on patient- and donor-characteristics and LB reports were analyzed retrospectively. Serum obtained before LT and at LB was analyzed for presence of recipient HLA antibody using Luminex <sup>®</sup> technology. MFI > 1000 was considered positive. In 63 pediatric LT recipients with a median follow-up of 72 months, the overall prevalence of de novo DSA was 60.3%. Most were directed against class II antigens (33/38, 86.8%). Preformed DSA were present in 30% of patients. Twenty-eight (28/63) patients (44.4%) presented at least one episode of TCMR, mostly (12/28, 43%) moderate (Banff 6-7). De novo DSA were significantly more frequent in patients with TCMR than in patients without (75% vs 48.6%, P = .03), and patients with preformed and de novo DSA had a significantly higher rate of TCMR than patients without any DSA (66.7% vs 20%, P = .02). Neither preformed DSA nor de novo DSA were associated with frequency or severity of TCMR. Recipients with lower weight at LT developed de novo DSA more frequently (P = .04). De novo DSA were highly prevalent in pediatric LT recipients. Although associated with the development of TCMR, they did not appear to impact the frequency or severity of TCMR or graft survival. Instead, de novo DSA may suggest a state of insufficient IS

Análise energética em sistema de produção de suínos com aproveitamento dos desejos como biofertilizante em pastagem Energy analysis in a swine production system with use of manure as biofertilizer in pasture

O objetivo deste trabalho foi estimar a quantidade de energia para a produção de suínos, em ciclo completo, e o balanço energético do sistema com reaproveitamento dos resíduos gerados como biofertilizante, em área de pastagem, utilizando dados médios de cinco ciclos, em granja comercial no município de Diamantina - MG. Quantificou-se o coeficiente energético de cada componente envolvido no processo produtivo de suínos terminados, tratamento dos resíduos e produção de pastagem de Brachiaria decumbens, nas formas de ração, trabalho humano, energia elétrica, máquinas e equipamentos, combustíveis e lubrificantes, instalações, produção de suínos vivos e produção de Brachiaria decumbens. A quantidade média de energia para produzir 1 kg de suíno vivo foi de 53,35 MJ. De toda energia empregada no sistema, 76,03% (1.067.106,07 MJ) referem-se às entradas e 23,97% (331.400 MJ) às saídas, resultando em coeficiente de eficiência energética de 0,31. A energia transformada em suínos para abate correspondeu a 55,58% (184.200 MJ) das saídas, ao passo que a pastagem de Brachiaria decumbens assumiu o valor de 44,42% (147.200 MJ).<br>This work objective was to esteem the amount of energy employed in a complete cycle swine production and the energy balance of the system with utilization of the generated manure as biofertilizer in pasture area, by using five cycles' average data, in a commercial farm in Diamantina municipal district - MG Brazil. The energy coefficient of each involved component was quantified in the productive process of finished swine, residues treatment and Brachiaria decumbens pasture production, in the form of ration, human labor, electric power, machines and equipments, fuel and lubricants, buildings, finished swine production and Brachiaria decumbens production. The average quantity of energy to produce 1 kg of alive swine was of 53.35 MJ. Of total employed energy in the system 76.03% (1,067,106.07 MJ) refers to the inputs and 23.97% (331,400 MJ) refers to the outputs, resulting in an energy efficiency coefficient of 0.31. The energy converted in swine for abate corresponded to 55.58% (184,200 MJ) of the outputs, while the pasture of Brachiaria decumbens reached a value of 44.42% (147,200 MJ)