Atherogenic Lipid Profile Of Brazilian Near-term Newborns.

Cardiovascular disease is the primary cause of death in Brazil. Recent studies have shown that low birth weight and preterm birth are linked to a higher prevalence of cardiovascular disease. The aim of the present study was to compare the levels of lipids and apolipoproteins and atherogenic indexes between term and near-term newborn infants. A sample of umbilical cord blood was obtained from 135 newborns (66 males) divided into two groups: 25 near-term neonates (35-36.6 weeks of gestational age) and 110 term neonates (37-42 weeks of gestational age). The total cholesterol concentrations were higher in the near-term neonates than in the term group (94.04 +/- 8.02 vs 70.42 +/- 1.63 mg/dl, P < 0.01), due to an increase in the LDL-cholesterol fraction in the near-term group (57.76 +/- 6.39 vs 34.38 +/- 1.29 mg/dl, P < 0.001). The atherogenic indexes (total cholesterol/HDL-cholesterol, LDL-cholesterol/HDL-cholesterol and apolipoprotein B/apolipoprotein A-I) were higher in the near-term group (P < 0.001, P < 0.001, and P < 0.05, respectively). The gestational age of the newborns was inversely correlated with total cholesterol and LDL-cholesterol, and also with the total cholesterol/HDL-cholesterol and LDL-cholesterol/HDL-cholesterol indexes. These findings demonstrate that the lipid profile is worse in the group of near-term neonates compared with the term group. Future studies are needed to determine if this atherogenic profile in near-term neonates can affect body metabolism, increasing the risk for cardiovascular diseases in adult life.38755-6

Experimental poisoning by Baccharis megapotamica var. weirii in buffalo

Five male 6-8 month-old Murrah buffalo calves were orally dosed with the fresh aerial parts of Baccharis megapotamica var. weirii at doses of 1, 3, 4, 5 and 10g/kg body weight (bw) (~1-10mg macrocyclic trichothecenes/kg/bw). The B. megapotamica used for the experiment was harvested on a farm where a recent spontaneous outbreak of poisoning caused by such plant had occurred. Clinical signs appeared 4-20 hours and 4 buffaloes died 18-49 hours after the ingestion of the plant. Clinical signs were apathy, anorexia, and watery diarrhea, fever, colic, drooling, muscle tremors, restlessness, laborious breathing and ruminal atony, and dehydration. The most consistent gross findings were restricted to the gastrointestinal (GI) tract consisted of varying degrees of edema and reddening of the mucosa of the forestomach. Histopathological findings consisted of varying degrees of necrosis of the epithelial lining of the forestomach and of lymphocytes within lymphoid organs and aggregates. Fibrin thrombi were consistently found in sub-mucosal vessels of the forestomach and in the lumen of hepatic sinusoids. It is suggested that dehydration, septicemia and disseminated intravascular coagulation participate in the pathogenesis of the intoxication and play a role as a cause of death. A subsample of B. megapotamica var. weirii was frozen-dried and ground and analyzed using UHPLC (Ultra High Performance Liquid Chromatography) with high resolution Time of Flight mass spectrometry and tandem mass spectrometry, it was shown that the plant material contained at least 51 different macrocyclic trichothecenes at a total level of 1.1-1.2mg/g. About 15-20% of the total trichothecenes contents was found to be monosaccharide conjugates, with two thirds of these being glucose conjugates and one third constituted by six aldopentose conjugates (probably xylose), which has never been reported in the literature

PH e condutividade elétrica do solo sob lâminas de irrigação e doses de adubação nitrogenada em bananeira.

O nitrogênio é um dos nutrientes mais necessários ao bom desenvolvimento e produção da bananeira. A adubação nitrogenada pode ser preparada por fontes de sais inorgânicos rapidamente disponíveis como o amônio, o nitrato e a uréia. A utilização da uréia pelos produtores se traduz pelo menor custo que esses fertilizantes possuem, porém, a possibilidade de aumento da acidez do solo, ou seja, a redução do pH e da saturação de base se tornam aspectos indesejados na aplicação desse fertilizante. Nas condições irrigadas, pode haver interações entre os níveis de água aplicados e as dosagens de adubos, fazendo com que o pH do solo e os níveis de condutividade elétrica (CE) do solo apresentem diferentes comportamentos em relação as condição de sequeiro. Além disso, a CE está relacionada ao conteúdo de água presente no solo, sendo que sua alteração está relacionada à diluição dos sais da solução. O objetivo do trabalho foi avaliar o comportamento do pH do solo e da CE do extrato de saturação ao longo do segundo ciclo da bananeira BRS Tropical com três doses de uréia sob quatro lâminas de irrigação nas condições edafoclimáticas do projeto Gorutuba, Norte de Minas.PDF. 097

Childhood And Adolescent Obesity: How Many Extra Calories Are Responsible For Excess Of Weight?

To review the main articles on energy imbalance and obesity in order to quantify the daily energy surplus associated with weight gain in children and adolescents. Articles published in the last ten years, indexed in electronic databases Medline (Pubmed) and SciELO-Br. In the Medline database, the descriptor energy gap was used and describes the energy values ​​associated with changes in body weight in individuals or populations. In SciELO-Br database, the descriptors obesity, energy metabolism, energy balance, and energy imbalance were used, once it was not possible to find national articles discussing the energy gap. In the pediatric population, four studies were performed and indicate that children and adolescents are gradually gaining weight due to a small, but persistent, daily positive energy balance of 70 to 160kcal above the total energy suitable for growth. The results suggest that small changes in daily eating behavior as well as physical activity would be enough to prevent future weight gain in this population. gradual weight gain can be explained by small daily average of positive energy balance, from 70 to 160kcal above the total energy suitable for growth. The incentive to small changes in eating behavior and physical activities that promotes daily reduction of 160kcal can be an accessible practice in order to block weight gain in this population.31252-

Deflection hardening of sustainable fiber–cement composites

In the present study sisal fiber–cement composites reinforced with 4% and 6% of short fibers were developed and their physical–mechanical behavior was characterized. To ensure the composite sustainability and durability, the ordinary Portland cement matrix was modified by adding fly ash and metakaolin, and the natural aggregate was substituted by 10% and 20% of recycled concrete aggregate. Flat sheets were cast in a self-compacted cement matrix and bending tests were performed to determine the first crack, postpeak strength and toughness of the composites. Cyclic flexural tests were carried out to determine the stiffness variation of composite due to cracking formation and propagation. It can be seen that the reinforcement provided by short sisal fibers for recycled cement matrices guaranteed a composite with multiple cracking and an increase of strength after the first crack. Reduction of stiffness and increase the damping capacity of composite are verified with progressive cracking.CAPES (PVE Program: Project 047/2012) and CNPqBrazilian agency FAPESBBrazilian agency CAPES through the PVE Progra

Potencial genético de progênies de feijão-caupi segregantes quanto ao tipo de inflorescência.

O objetivo deste trabalho foi avaliar o potencial genético produtivo de progênies de feijão?caupi (Vigna unguiculata) segregantes quanto ao tipo da inflorescência