945 research outputs found
Poverty Effects from Trade Liberalisation in Argentina
This paper aims at analyzing the linkages between international trade openness and poverty in Argentina. Under a specific-factors setting, a two-step procedure is presented. In the first stage the change in prices of goods and factors in both tradable and non-tradable sectors, after a trade liberalisation episode, is considered. In a second step, these variations are applied to assess the changes in poverty and households’ welfare. A micro-simulation approach, using households’ survey data, is applied in this last stage. The results of the research are important since they provide an assessment of the impact trade policies have on poverty.
Design and cryogenic operation of a hybrid quantum-CMOS circuit
Silicon-On-Insulator nanowire transistors of very small dimensions exhibit
quantum effects like Coulomb blockade or single-dopant transport at low
temperature. The same process also yields excellent field-effect transistors
(FETs) for larger dimensions, allowing to design integrated circuits. Using the
same process, we have co-integrated a FET-based ring oscillator circuit
operating at cryogenic temperature which generates a radio-frequency (RF)
signal on the gate of a nanoscale device showing Coulomb oscillations. We
observe rectification of the RF signal, in good agreement with modeling
On the nature of X-Ray Flashes in the SWIFT era
X-Ray Flashes (XRFs) are soft gamma-ray bursts whose nature is not clear.
Their soft spectrum can be due to cosmological effects (high redshift), an
off-axis view of the jet or can be intrinsic to the source. We use SWIFT
observations to investigate different scenarios proposed to explain their
origin. We have made a systematic analysis of the afterglows of XRFs with known
redshift observed by SWIFT. We derive their redshift and luminosity
distributions, and compare their properties with a sample of normal GRBs
observed by the same instrument. The high distance hypothesis is ruled out by
the redshift distribution of our sample of XRFs, indicating that, at least for
our sample, the off-axis and sub-energetic hypotheses are preferred. Of course,
this does not exclude that some XRFs without known redshift could be at high
distance. However we find that taking into account the sensitivity of the BAT
instrument, XRFs cannot be detected by SWIFT beyond ~ 3. The luminosity
distribution of XRF afterglows is similar to the GRB one. This would rule out
most off-axis models, but for the homogeneous jet model. However this model
predicts a GRB rate uncomfortably near the observed rate of supernovae. This
implies that XRFs, at least those of our sample, are intrinsically soft.Comment: 4 pages, 2 color figures. Astronomy and Astrophysics Letters,
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Pauli spin blockade in CMOS double quantum dot devices
Silicon quantum dots are attractive candidates for the development of
scalable, spin-based qubits. Pauli spin blockade in double quantum dots
provides an efficient, temperature independent mechanism for qubit readout.
Here we report on transport experiments in double gate nanowire transistors
issued from a CMOS process on 300 mm silicon-on-insulator wafers. At low
temperature the devices behave as two few-electron quantum dots in series. We
observe signatures of Pauli spin blockade with a singlet-triplet splitting
ranging from 0.3 to 1.3 meV. Magneto-transport measurements show that
transitions which conserve spin are shown to be magnetic-field independent up
to B = 6 T.Comment: 5 pages , 4 figure
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Secreted factors from olfactory mucosa cells expanded as free-floating spheres increase neurogenesis in olfactory bulb neurosphere cultures.
BACKGROUND: The olfactory epithelium is a neurogenic tissue comprising a population of olfactory receptor neurons that are renewed throughout adulthood by a population of stem and progenitor cells. Because of their relative accessibility compared to intra-cranially located neural stem/progenitor cells, olfactory epithelium stem and progenitor cells make attractive candidates for autologous cell-based therapy. However, olfactory stem and progenitor cells expand very slowly when grown as free-floating spheres (olfactory-spheres) under growth factor stimulation in a neurosphere assay. RESULTS: In order to address whether olfactory mucosa cells extrinsically regulate proliferation and/or differentiation of immature neural cells, we cultured neural progenitor cells derived from mouse neonatal olfactory bulb or subventricular zone (SVZ) in the presence of medium conditioned by olfactory mucosa-derived spheres (olfactory-spheres). Our data demonstrated that olfactory mucosa cells produced soluble factors that affect bulbar neural progenitor cell differentiation but not their proliferation when compared to control media. In addition, olfactory mucosa derived soluble factors increased neurogenesis, especially favouring the generation of non-GABAergic neurons. Olfactory mucosa conditioned medium also contained several factors with neurotrophic/neuroprotective properties. Olfactory-sphere conditioned medium did not affect proliferation or differentiation of SVZ-derived neural progenitors. CONCLUSION: These data suggest that the olfactory mucosa does not contain factors that are inhibitory to neural stem/progenitor cell proliferation but does contain factors that steer differentiation toward neuronal phenotypes. Moreover, they suggest that the poor expansion of olfactory-spheres may be in part due to intrinsic properties of the olfactory epithelial stem/progenitor cell population.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are
Secreted factors from olfactory mucosa cells expanded as free-floating spheres increase neurogenesis in olfactory bulb neurosphere cultures
<p>Abstract</p> <p>Background</p> <p>The olfactory epithelium is a neurogenic tissue comprising a population of olfactory receptor neurons that are renewed throughout adulthood by a population of stem and progenitor cells. Because of their relative accessibility compared to intra-cranially located neural stem/progenitor cells, olfactory epithelium stem and progenitor cells make attractive candidates for autologous cell-based therapy. However, olfactory stem and progenitor cells expand very slowly when grown as free-floating spheres (olfactory-spheres) under growth factor stimulation in a neurosphere assay.</p> <p>Results</p> <p>In order to address whether olfactory mucosa cells extrinsically regulate proliferation and/or differentiation of immature neural cells, we cultured neural progenitor cells derived from mouse neonatal olfactory bulb or subventricular zone (SVZ) in the presence of medium conditioned by olfactory mucosa-derived spheres (olfactory-spheres). Our data demonstrated that olfactory mucosa cells produced soluble factors that affect bulbar neural progenitor cell differentiation but not their proliferation when compared to control media. In addition, olfactory mucosa derived soluble factors increased neurogenesis, especially favouring the generation of non-GABAergic neurons. Olfactory mucosa conditioned medium also contained several factors with neurotrophic/neuroprotective properties. Olfactory-sphere conditioned medium did not affect proliferation or differentiation of SVZ-derived neural progenitors.</p> <p>Conclusion</p> <p>These data suggest that the olfactory mucosa does not contain factors that are inhibitory to neural stem/progenitor cell proliferation but does contain factors that steer differentiation toward neuronal phenotypes. Moreover, they suggest that the poor expansion of olfactory-spheres may be in part due to intrinsic properties of the olfactory epithelial stem/progenitor cell population.</p
Charge dynamics and spin blockade in a hybrid double quantum dot in silicon
Electron spin qubits in silicon, whether in quantum dots or in donor atoms,
have long been considered attractive qubits for the implementation of a quantum
computer due to the semiconductor vacuum character of silicon and its
compatibility with the microelectronics industry. While donor electron spins in
silicon provide extremely long coherence times and access to the nuclear spin
via the hyperfine interaction, quantum dots have the complementary advantages
of fast electrical operations, tunability and scalability. Here we present an
approach to a novel hybrid double quantum dot by coupling a donor to a
lithographically patterned artificial atom. Using gate-based rf reflectometry,
we probe the charge stability of this double quantum dot system and the
variation of quantum capacitance at the interdot charge transition. Using
microwave spectroscopy, we find a tunnel coupling of 2.7 GHz and characterise
the charge dynamics, which reveals a charge T2* of 200 ps and a relaxation time
T1 of 100 ns. Additionally, we demonstrate spin blockade at the inderdot
transition, opening up the possibility to operate this coupled system as a
singlet-triplet qubit or to transfer a coherent spin state between the quantum
dot and the donor electron and nucleus.Comment: 6 pages, 4 figures, supplementary information (3 pages, 4 figures
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