478 research outputs found
A [SU(6)] FLAVOR MODEL WITHOUT MIRROR FERMIONS
We introduce a three family extension of the Pati-Salam model which is
anomaly-free and contains in a single irreducible representation the known
quarks and leptons without mirror fermions. Assuming that the breaking of the
symmetry admits the implementation of the survival hypothesis, we calculate the
mass scales using the renormalization group equation. Finally we show that the
proton remains perturbatively stable.Comment: Z PHYS. C63, 339 (1994
Extra Dimensions at the Weak Scale and Deviations from Newtonian Gravity
We consider theories in which the Standard Model gauge fields propagate in
extra dimensions whose size is around the electroweak scale. The Standard Model
quarks and leptons may either be localized to a brane or propagate in the bulk.
This class of theories includes models of Scherk-Schwarz supersymmetry
breaking and universal extra dimensions. We consider the problem of stabilizing
the volume of the extra dimensions. We find that for a large class of
stabilization mechanisms the field which corresponds to fluctuations of the
volume remains light even after stabilization, and has a mass in the
eV range. In particular this is the case if stabilization does not involve
dynamics at scales larger than the cutoff of the higher dimensional Standard
Model, and if the effective theory below the compactification scale is four
dimensional. The mass of this field is protected against large radiative
corrections by the general covariance of the higher dimensional theory and by
the weakness of its couplings, which are Planck suppressed. Its couplings to
matter mediate forces whose strength is comparable to that of gravity and which
can give rise to potentially observable deviations from Newton's Law at
sub-millimeter distances. Current experiments investigating short distance
gravity can probe extra dimensions too small to be accessible to current
collider experiments. In particular for a single extra dimension stabilized by
the Casimir energy of the Standard Model fields compactification radii as small
as 5 inverse TeV are accessible to current sub-millimeter gravity experiments.Comment: Minor corrections, conclusions unchanged. References adde
Model for fermion mass matrices and the origin of quark-lepton symmetry
Several phenomenological features of fermion masses and mixings can be
accounted for by a simple model for fermion mass matrices, which suggests an
underlying U(2) horizontal symmetry. In this context, it is also proposed how
an approximate quark-lepton symmetry can be achieved without unified gauge
theories.Comment: 12 pages, RevTex. Minor changes, some references adde
The Notch pathway drives the ability of the bone marrow niche to promote RNA editing in multiple myeloma
Multiple myeloma (MM) is the second most frequently diagnosed hematological malignancy, and despite all the therapeutic advances it remains incurable due to the development of drug resistance. Recently, RNA editing has emerged as one of the important mechanisms that determines expression variability and therefore may be involved in the development of resistance to standard therapy. This process is mediated by adenosine deaminase acting on RNA (ADAR) enzymes that convert adenosines to inosines (A-->I editing) in double-stranded RNA (dsRNA) substrates. We hypothesize that ADAR1 activation in MM cells may be promoted by the normal cells of the bone marrow (BM) niche through the release of pro-tumor factor controlled by the oncogenic Notch pathway. Indeed, Notch is known to be hyperactivated in myeloma and it is crucial for the pathologic crosstalk between tumor cells and the surrounding BM microenvironment. Aim of this work was to investigate how the Notch pathway contributes to the ability of the BM microenvironment stromal cells on their ability to boost RNA editing and drug resistance in MM, in order to provide the rationale for a Notch-directed therapy that may allow to inhibit the progression of this disease
Phenomenology of Supersymmetric Theories with and without R-Parity
We review supersymmetry models with and without R-parity. After briefly
describing the Minimal Supersymetric Standard Model and its particle content we
move to models where R-parity is broken, either spontaneously or explicitly. In
this last case we consider the situation where R-parity is broken via bilinear
terms in the superpotential. The radiative breaking of these models is
described in the context of -- and ---- unification.
Finally we review the phenomenology of these R-parity violating models.Comment: 9 pages, 5 Figures in Postscript. Talk given at the EuroConference on
Frontiers in Particle Astrophysics and Cosmology, San Feliu de Guixols,
Spain, 30 September - 5 October, 200
Lepton Flavor Violating Processes and Muon g-2 in Minimal Supersymmetric SO(10) Model
In the recently proposed minimal supersymmetric SO(10) model, the neutrino
Dirac Yukawa coupling matrix, together with all the other fermion mass
matrices, is completely determined once free parameters in the model are
appropriately fixed so as to accommodate the recent neutrino oscillation data.
Using this unambiguous neutrino Dirac Yukawa couplings, we calculate the lepton
flavor violating (LFV) processes and the muon g-2 assuming the minimal
supergravity scenario. The resultant rates of the LFV processes are found to be
large enough to well exceed the proposed future experimental bound, while the
magnitude of the muon g-2 can be within the recent result by Brookhaven E821
experiment. Furthermore, we find that there exists a parameter region which can
simultaneously realize the neutralino cold dark matter abundance consistent
with the recent WMAP data.Comment: 18 pages, 10 figures. The version to be published in Phys. Rev.
The projector on physical states in loop quantum gravity
We construct the operator that projects on the physical states in loop
quantum gravity. To this aim, we consider a diffeomorphism invariant functional
integral over scalar functions. The construction defines a covariant,
Feynman-like, spacetime formalism for quantum gravity and relates this theory
to the spin foam models. We also discuss how expectation values of physical
quantity can be computed.Comment: 15 pages, 2 figures, substantially revised versio
Model Independent Higgs Boson Mass Limits at LEP
We derive model-independent constraints on Higgs mass and couplings from
associated signals for higher masses, accessible at LEP2. This work is
motivated by the fact that, in many extensions of the standard model, the Higgs
boson can have substantial "invisible" decay modes, for example, into light or
massless weakly interacting Goldstone bosons associated to the spontaneous
violation of lepton number below the weak scale.Comment: FTUV/93-19, 13 pag + 2 figures(not included but available upon
request), Late
Composite quarks and leptons in higher space-time dimensions
A new approach towards the composite structure of quarks and leptons in the
context of the higher dimensional unified theories is proposed. Owing to the
certain strong dynamics, much like an ordinary QCD, every possible vectorlike
multiplets of composites appear in higher dimensional bulk space-time, however,
through a proper Sherk-Schwarz compactification only chiral set of composite
quarks and leptons survive as the massless states in four dimensions. In this
scenario restrictions related with the 't Hooft's anomaly matching condition
are turned out to be avoided and, as a result, the composite models look rather
simple and economic. We demonstrate our approach by an explicit construction of
model of preons and their composites unified in the supersymmetric SU(5) GUT in
five space-time dimensions. The model predicts exactly three families of the
composite quarks and leptons being the triplets of the chiral horizontal
symmetry SU(3)_h which automatically appears in the composite spectrum when
going to ordinary four dimensions.Comment: 13 pages, tcilatex, no figures, v2 - misprints correcte
Charged lepton Flavor Violation in Supersymmetry with Bilinear R-Parity Violation
The simplest unified extension of the Minimal Supersymmetric Standard Model
with bi-linear R-parity violation naturally predicts a hierarchical neutrino
mass spectrum, suitable to explain atmospheric and solar neutrino fluxes. We
study whether the individual violation of the lepton numbers L_{e,mu,tau} in
the charged sector can lead to measurable rates for BR(mu->e gamma)and
$BR(tau-> mu gamma). We find that some of the R-parity violating terms that are
compatible with the observed atmospheric neutrino oscillations could lead to
rates for mu->e gamma measurable in projected experiments. However, the Delta
m^2_{12} obtained for those parameters is too high to be compatible with the
solar neutrino data, excluding therefore the possibility of having measurable
rates for mu->e gamma in the model.Comment: 29 pages, 8 figures. Constraint from solar neutrino data included,
conclusions changed respect v
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