2,507 research outputs found
BIM Approach in Construction Safety-A Case Study on Preventing Falls from Height
The construction industry has one of the highest occupational accident incidence rates among all economic sectors. Currently, building information modelling (BIM) appears to be a valuable tool for analysing occupational safety issues throughout the construction life cycle of projects, helping to avoid hazards and risks and, consequently, increasing safety. This work investigates BIM methodology and the application of related technologies for building safety planning and demonstrates the potential of this technology for the integrated implementation of safety measures during the design phase and construction site management. The first step consisted of a literature review on applying BIM-related technologies for safety in the design and planning phases. Following this, to show the potentialities of construction simulation, a case study based on BIM 4D to prevent falls from height was developed. With BIM 4D, it is possible to follow the construction process over time, giving the construction safety technicians, designers, supervisors and managers the capability to analyse, in each phase, the potential risks and identify which safety measures should be implemented. BIM can effectively integrate safety measures from the design phase to the construction and use phase and enable integrated safety planning within construction planning, leading to reliable safety management throughout the construction process
Spatial and temporal distribution of benthic macroinvertebrates in a Southeastern Brazilian river.
A fauna de macroinvertebrados bentônicos é estruturada por fatores físicos e químicos que determinam os microhábitats, incluindo a disponibilidade de alimento, a existência de refúgios contra predadores e tempestades, o sucesso reprodutivo e outros parâmetros biológicos. O objetivo deste estudo foi investigar a distribuição espaço-temporal da comunidade de macroinvertebrados bentônicos na bacia do Rio Macaé, estado do Rio de Janeiro, Brasil. De acordo com o Habitat Assessment Field Data Sheet High Gradient Streams (Barbour et al., 1999), os cinco locais coletados são considerados como referência para propósito de biomonitoramento. Apesar das diferenças em parâmetros hidrográficos (largura, profundidade e vazão médias), os parâmetros físico-químicos e a composição dos grupos de alimentação funcional foram similares entre os locais, com exceção da área mais preservada, onde a porcentagem de organismos cortadores foi maior. De acordo com a análise de correspondência, há uma clara distinção entre áreas de remanso e de correnteza. De fato, o substrato folhiço de correnteza apresentou a fauna mais rica e abundante, enquanto o substrato folhiço de fundo apresentou o maior número de táxons exclusivos. A análise de agrupamento considerando os dados dos locais de coleta indicou que a variação temporal foi o fator mais importante na estruturação das comunidades nos hábitats estudados
Numerical investigation of a refractive index SPR D-type optical fiber sensor using COMSOL multiphysics
Mutual information rate and bounds for it
The amount of information exchanged per unit of time between two nodes in a
dynamical network or between two data sets is a powerful concept for analysing
complex systems. This quantity, known as the mutual information rate (MIR), is
calculated from the mutual information, which is rigorously defined only for
random systems. Moreover, the definition of mutual information is based on
probabilities of significant events. This work offers a simple alternative way
to calculate the MIR in dynamical (deterministic) networks or between two data
sets (not fully deterministic), and to calculate its upper and lower bounds
without having to calculate probabilities, but rather in terms of well known
and well defined quantities in dynamical systems. As possible applications of
our bounds, we study the relationship between synchronisation and the exchange
of information in a system of two coupled maps and in experimental networks of
coupled oscillators
Treatment of Hepatitis C Virus Infection in Kidney Transplant Recipients: Case Report
Chronic hepatitis C virus (HCV) infection exists in a large proportion of patients undergoing renal transplantation. Nowadays it is not considered to be an absolute contraindication to transplantation; however, it is associated with an increased risk for the patient and accounts for a shorter half-life of the renal allograft. We present three transplant recipients who displayed serious hepatic dysfunction after renal transplantation due to an HCV infection. In two of these cases, the liver biopsies established the diagnosis of FCH. In the third case, the liver biopsy was compatible with the early stages of FCH. All patients were started on peg-interferon alfa 2-b and ribavirin with subsequent normalization of hepatic function and early complete viral responses
Comparative studies on energy efficiency and GHG emissions between conventional and organic olive groves in Greece and Portugal
Nowadays, traditional farming based on achieving high yields using high inputs, shifts gradu-ally towards maximum possible crop yield using minimal inputs in an optimized way or to-wards organic farming. This is usually accomplishing by low yield of high quality products without using conventional agrochemicals (i.e. fertilizers, pesticides). In general, this last ap-proach leads to lower energy consumption per unit area of land, therefore lower cost and reduced greenhouse gas (GHG) emissions. However, in a global perspective it has the risk of significant total production reduction. Hence, it is vital to consider energy efficiency im-provement, namely the decrease of primary energy consumption for the production of a unit of agricultural product (expressed in weight or volume units), within the farm boundaries. Im-provement of energy efficiency is a key parameter affecting positively the overall efficiency of crop farming systems in terms of energy and GHG emissions. In the present paper, two show cases of olive groves in Greece (“Sterea Ellada” region) and Portugal (“Alentejo” re-gion) were compared to illustrate the effect on energy efficiency and GHG emissions when moving from conventional to organic olive grove cultivations in these different locations. The analysis was based on two simple framework models using information provided by farmers and literature data regarding the inputs and outputs of each olive grove. The models were adjusted according to the olives’ variety, the agricultural practices followed and the location of the production system. Considering the specific energy consumption per unit of product, in the case of the Greek olive grove, organic farming reduces energy consumption by 13.9%, while the final yield is reduced by 30%. GHG emissions are reduced by 58%. In the case of the Portuguese olive grove, organic farming significantly reduces crop yield (54.5%), while, energy efficiency is improved by 9.7% and GHG emissions are reduced by 26%
Self interacting Brans Dicke cosmology and Quintessence
Recent cosmological observations reveal that we are living in a flat
accelerated expanding universe. In this work we have investigated the nature of
the potential compatible with the power law expansion of the universe in a self
interacting Brans Dicke cosmology with a perfect fluid background and have
analyzed whether this potential supports the accelerated expansion. It is found
that positive power law potential is relevant in this scenario and can drive
accelerated expansion for negative Brans Dicke coupling parameter . The
evolution of the density perturbation is also analyzed in this scenerio and is
seen that the model allows growing modes for negative .Comment: 8pages, 5 figures, PRD style, some changes are made, figures added,
reference added. To be published in Int. J. Mod. Phys.
Influence of water chemistry and environmental degradation on macroinvertebrate assemblages in a river basis in south-east Brazil.
Seven sites of the Guapimirim river basin were studied during three sampling periods based on the rain regime: end of wet season (May 1998), dry season (August 1998), and wet season (January 1999). Four substrates were collected at each site: sand, stony substrates, litter in pool areas and litter in riffle areas. Relationships between macroinvertebrate assemblages, water chemistry variables and environmental degradation were examined using canonical correspondence analysis (CCA). According to CCA, concentrations of dissolved oxygen and chloride, and the environmental degradation, measured by the Riparian Channel Environment index, exhibited the strongest relationship to macroinvertebrate assemblages. Overall, the loss of community diversity measured by the Shannon Index along the degradation gradient was observed. Some taxa were shown to be sensitive to water pollution, especially among Plecoptera, Trichoptera, Coleoptera and some Ephemeroptera, while others such as Simuliidae, Odonata and molluscs were tolerant to moderate levels of pollutants. The Chironomidae were the only group tolerant to a high level of pollutants and degradation
Single-Cell Analysis Uncovers Osteoblast Factor Growth Differentiation Factor 10 as Mediator of Vascular Smooth Muscle Cell Phenotypic Modulation Associated with Plaque Rupture in Human Carotid Artery Disease
(1) Background: Vascular smooth muscle cells (VSMCs) undergo a complex phenotypic switch in response to atherosclerosis environmental triggers, contributing to atherosclerosis disease progression. However, the complex heterogeneity of VSMCs and how VSMC dediffer-entiation affects human carotid artery disease (CAD) risk has not been clearly established. (2) Method: A single-cell RNA sequencing analysis of CD45 12 cells derived from the atherosclerotic aorta of Apolipoprotein E-deficient (Apoe 12/ 12) mice on a normal cholesterol diet (NCD) or a high cholesterol diet (HCD), respecting the site-specific predisposition to atherosclerosis was performed. Growth Differentiation Factor 10 (GDF10) role in VSMCs phenotypic switch was investigated via flow cytometry, immunofluorescence in human atherosclerotic plaques. (3) Results: scRNAseq analysis revealed the transcriptomic profile of seven clusters, five of which showed disease-relevant gene signature of VSMC macrophagic calcific phenotype, VSMC mesenchymal chondrogenic phenotype, VSMC inflammatory and fibro-phenotype and VSMC inflammatory phenotype. Osteoblast factor GDF10 involved in ossification and osteoblast differentiation emerged as a hallmark of VSMCs undergoing phenotypic switch. Under hypercholesteremia, GDF10 triggered VSMC osteogenic switch in vitro. The abundance of GDF10 expressing osteogenic-like VSMCs cells was linked to the occurrence of carotid artery disease (CAD) events. (4) Conclusions: Taken together, these results provide evidence about GDF10-mediated VSMC osteogenic switch, with a likely detrimental role in atherosclerotic plaque stability
- …