Kaon production and propagation at intermediate relativistic energies

We systematically study $K^+$ observables in nucleus-nucleus collisions at 1-2 A GeV within the Boltzmann-Uehling-Uhlenbeck (BUU) transport model. We compare our calculations with the KaoS data on the kaon multiplicities and spectra. In addition, the kaon collective flow is computed and compared with the FOPI and KaoS data. We show, that the elliptic kaon flow measured recently by the KaoS Collaboration is best described by using the Brown-Rho parametrization of the kaon potential ($U_K(\rho_0) \simeq 30$ MeV).Comment: 21 pages, 3 tables, 17 figures; references added; version accepted in PR

Higher excitations of ω\omega and ϕ\phi in dilepton spectra

We consider lepton pair production via two-hadron annihilation through various isoscalar vector mesons within hot, baryon-free matter. This is tantamount to constructing effective form factors which we model using a vector-meson-dominance approach and compare with experiment. In particular, we consider the reactions $\pi\rho\to e^+e^-$ and $\bar K K^{*}(892)$ + c.c. $\to e^+e^-$. We find that $\omega(1390)$ and $\phi(1680)$ are visible in the mass spectrum for the thermal production rate above the $\pi^{+}\pi^{-} \to e^+e^-$ tail and even above the $\pi a_{1}\to e^+e^-$ results---both of which were considered important in their respective mass regions.Comment: RevTeX, 9 pages, 6 (uuencoded) figures; to appear in Phys. Rev

Antiproton-nucleus electromagnetic annihilation as a way to access the proton timelike form factors

Contrary to the reaction pbar + p --> e+ e- with a high momentum incident antiproton on a free target proton at rest, in which the invariant mass M of the (e+ e-) pair is necessarily much larger than the (pbar p) mass, in the reaction pbar + d --> n e+ e- the value of M can take values near or below the (pbar p) mass. In the antiproton-deuteron electromagnetic annihilation, this allows to access the proton electromagnetic form factors in the time-like region of q^2 near the (pbar p) threshold. We estimate the cross section dsigma(pbar +d --> e+ e- n)/dM for an antiproton beam momentum of 1.5 GeV/c. We find that near the (pbar p) threshold this cross section is about 1 pb/MeV. The case of heavy nuclei target is also discussed. Elements of experimental feasibility are presented for the process pbar + d --> n e+ e- in the context of the Panda project.Comment: 14 pages, 11 figures. submitted to EPJ

Photoabsorption on nuclei

We calculate the total photoabsorption cross section on nuclei in the energy range from 300 MeV to 1 GeV within the framework of a semi-classical phase space model. Besides medium modifications like Fermi motion and Pauli blocking we focus on the collision broadening of the involved resonances. The resonance contributions to the elementary cross section are fixed by fits to partial wave amplitudes of pion photoproduction. The cross sections for $N \, R \to N \, N$, needed for the calculation of collision broadening, are obtained by detailed balance from a fit to $N \, N \to N \, N \, \pi$ cross sections. We show that a reasonable collision broadening is not able to explain the experimentally observed disappearance of the $D_{13}(1520)$-resonance in the photoabsorption cross section on nuclei.Comment: 26 pages Latex including 9 postscript figure

Photoproduction of pions and etas in nuclei

We calculate the cross sections for inclusive one-pion, two-pion and eta photoproduction in nuclei in the photon energy range from 300 MeV to 900 MeV within the framework of a semi-classical BUU transport model. Our results are compared with existing experimental data and discussed with respect to a calculation of the total photoabsorption cross section.Comment: 30 pages LaTeX including 13 postscript figure

The origin of human chromosome 2 analyzed by comparative chromosome mapping with a DNA microlibrary

Fluorescencein situ hybridization (FISH) of microlibraries established from distinct chromosome subregions can test the evolutionary conservation of chromosome bands as well as chromosomal rearrangements that occurred during primate evolution and will help to clarify phylogenetic relationships. We used a DNA library established by microdissection and microcloning from the entire long arm of human chromosome 2 for fluorescencein situ hybridization and comparative mapping of the chromosomes of human, great apes (Pan troglodytes, Pan paniscus, Gorilla gorilla, Pongo pygmaeus) and Old World monkeys (Macaca fuscata andCercopithecus aethiops). Inversions were found in the pericentric region of the primate chromosome 2p homologs in great apes, and the hybridization pattern demonstrates the known phylogenetically derived telomere fusion in the line that leads to human chromosome 2. The hybridization of the 2q microlibrary to chromosomes of Old World monkeys gave a different pattern from that in the gorilla and the orang-utan, but a pattern similar to that of chimpanzees. This suggests convergence of chromosomal rearrangements in different phylogenetic lines

Calix[4]arene-Based Sensitizers for Host-Guest Supramolecular Dyads for Solar Energy Conversion in Photoelectrochemical Cells

The photogeneration of electricity and solar fuels by solar irradiation in photoelectrochemical cells is one of the sectors with the highest growth potential in the decarbonised society. However, the use of different components, in particular photosensitizers and catalysts, can present problems of charge transfer efficiency at the interface, leading to lower final efficiencies. In this work we present novel integrated photosensitizer-catalyst dyads based on robust and, at the same time, flexible host-guest non-covalent interactions through the use of calix[4]arene cavities. Current photogeneration in photoelectrochemical cells showed twice greater efficiency in the integrated calixarene-based host-guest dyads compared to the traditional architecture based on the separate photosensitizer-catalyst pair. Molecular dynamics studies have shown that the enhanced performance originates from an optimization of the distances between the centres of the photosensitizer, catalyst and semiconductor involved in the charge transfer processes, thus allowing a higher final efficiency of the charge photogeneration process

Mitomycin-ifosfamide-cisplatinum (MIP) vs MIP-interferon vs cisplatinum-carboplatin in metastatic non-small-cell lung cancer: a FONICAP randomised phase II study. Italian Lung Cancer Task Force.

The FONICAP group is screening, with randomised phase II studies, the activity of new chemotherapy programmes for advanced non-small-cell lung cancer (NSCLC) looking for regimens with > 30% activity. In the present study, three regimens were tested: MIP (mitomycin 6 mg m-2, ifosfamide 3 g m-2, cisplatinum 80 mg m-2 on day 1 every 28 days); MIP-IFN (MIP and interferon alpha-2b 3 MU s.c. three times a week); and PC (cisplatinum 60 mg m-2 and carboplatin 400 mg m-2 on day 1 every 28 days). Overall 93 chemotherapy-naive patients were enrolled: 23 received MIP, 27 received MIP-IFN and 43 received PC. Eighty per cent of the patients had stage IV and 20% stage IIIb disease (positive pleural effusion or supraclavicular nodes). Response rates were as follows: MIP = 9% (95% CI 1-28%), MIP-IFN = 7% (95% CI 1-24%) and PC = 14% (95% CI 5-28%). The overall median survival was 183 days. Grade III-IV leucopenia was observed in 36% of patients treated with MIP-IFN vs 10% in the other two arms, and thrombocytopenia grade III-IV was reported in nearly 10% of patients overall. In conclusion, (1) all three regimens investigated have poor activity (< 30%); (2) when tested in multicentre randomised phase II trials, MIP displays lower activity than in phase II trials; (3) PC has similar activity to other platinum-containing regimens; (4) randomised phase II studies are a reliable and quick method of determining the anti-tumour activity of novel chemotherapeutic regimens in NSCLC

Pion-Production in Heavy-Ion Collisions at SIS energies

We investigate the production of pions in heavy-ion collisions in the energy range of $1$ - $2$ GeV/A. The dynamics of the nucleus-nucleus collisions is described by a set of coupled transport equations of the Boltzmann-Uehling-Uhlenbeck type for baryons and mesons. Besides the $N(938)$ and the $\Delta(1232)$ we also take into account nucleon resonances up to masses of $1.9 GeV/c^2$ as well as $\pi$-, $\eta$- and $\rho$-mesons. We study in detail the influence of the higher baryonic resonances and the $2\pi$-production channels ($NN\to NN \pi\pi$) on the pion spectra in comparison to $\pi^-$ data from $Ar + KCl$ collisions at $1.8$ GeV/A and $\pi^0$-data for $Au+Au$ at 1.0 GeV/A. We, furthermore, present a detailed comparison of differential pion angular distributions with the BEVALAC data for Ar + KCl at 1.8 GeV/A. The general agreement obtained indicates that the overall reactions dynamics is well described by our novel transport approach.Comment: 31 pages, 18 figures (inlcuded), to appear in Z. Phys.

Charmless Three-Body Baryonic B Decays

Motivated by recent data on B-> p pbar K decay, we study various charmless three-body baryonic B decay modes, including Lambda pbar pi, Sigma0 pbar pi, p pbar pi, p pbar Kbar0, in a factorization approach. These modes have rates of order 10^{-6}. There are two mechanisms for the baryon pair production, current-produced and transition. The behavior of decay spectra from these baryon production mechanisms can be understood by using QCD counting rules. Predictions on rates and decay spectra can be checked in the near future.Comment: 26 pages, 9 figures; version to appear in Phys. Rev.