Analysis of customer profiles on an electrical distribution network.

It has become increasingly important for electrical distribution companies to understand the drivers of demand. The maximum demand at any given substation can vary materially on an annual basis which means it is difficult to create a load related investment plan that is robust and stable. Currently, forecasts are based only on historical demand with little understanding about contributions to load profiles. In particular, the unique diversity of customers on any particular substation can affect load profile shape and future forecasts. Domestic and commercial customers can have very different behaviours generally and within these groups there is room for variation due to economic conditions and building types. This paper analyses customer types associated to substations on a distribution network by way of principal component analysis and identification of substations which deviate from the national demand trend. By examining the variance spread of this deviation, data points can be labelled in the principal component space. Groups of substations can then be categorised as having typical or atypical load profiles. This will support the need for further investigation into particular customer types and highlight the key factors of customer categorisation

Re-framing Zimbabwe's public agricultural extension services: Institutional analysis and stakeholders views

Research and Development/Tech Change/Emerging Technologies,

Threats to soil quality in Denmark - A review of existing knowledge in the context of the EU Soil Thematic Strategy

The EU Commission is preparing a proposal for a Soil Framework Directive with the purpose of protecting the soil resources in Europe. The proposal identifies six major threats to the sustained quality of soils in Europe. This report addresses the threats that are considered most important under the prevailing soil and climatic conditions in Denmark: compaction, soil organic matter decline, and erosion by water and tillage. For each of these threats, the relevance and damage to soil functions as well as the geographic distribution in Denmark are outlined. We suggest a procedure for identifying areas at risk. This exercise involves an explicit identification of: i) the disturbing agent (climate / management) exerting the pressures on soil, and ii) the vulnerability of the soil to those stresses. Risk reduction targets, measures required to reach these targets, and the knowledge gaps and research needs to effectively cope with each threat are discussed. Our evaluation of the threats is based on soil resilience to the imposed stresses. Subsoil compaction is considered a severe threat to Danish soils due to frequent traffic with heavy machinery in modern agriculture and forestry. The soil content of organic matter is critically low for a range of Danish soils, which should be counteracted by appropriate management options. Soil erosion by tillage, and to a lesser degree by water, adversely affects soil quality on much of the farmland because degradation rates are much higher than generation of soil

Soil Quality Management - Concepts and Terms

The industrialization of agriculture and the concurrent increase in societal concerns on environmental protection and food quality have put focus on agricultural management and its impact on soil quality. Soil quality involves the ability of the soil to maintain an appropriate productivity, while simultaneously reducing the effect on the environment and contributing to human health. This development has changed society’s expectations to science and there is an urgent need to improve the communication among researchers from different scientific disciplines. The interaction of scientists with decision-makers is a topic of utmost relevance for future developments in agriculture. Reflexive objectivity denotes the exercise of raising one’s consciousness of the cognitive context, i.e. societal priorities and the values and goals of the researcher. The term sustainability comprehends the priorities in the cognitive context and thus constitutes a valuable tool for expressing the basis of scientific work. Soil quality evaluations should include awareness of the stability of any given quality attribute to disturbance and stress. This implies addressing resistance and resilience of the soil functions and/or the physical form in question. Most existing literature on soil quality focuses on assessment of soil quality rather than the management tools available to influence soil quality. Identification of management thresholds rather than soil quality indicator thresholds is suggested as an important means of implementing the soil quality concept. The major challenges facing modern agriculture include proper nutrient cycling, maintained functions and diversity of soil, protection of an appropriate physical form, and avoidance of chemical contamination. It is suggested that these challenges and problems as related to the soil quality concept are discussed in the framework expounded above

Breeding for Resistance to Infectious Diseases in Small Ruminants

Livestock Production/Industries,

FARMERS RESOURCE – USE AND TECHNICAL EFFICIENCY IN COWPEA PRODUCTION IN NIGERIA

In Nigeria, the use of stochastic frontier to estimate farm level efficiency effects is still at the rudimentary level and is beginning to build up. Few studies have been undertaken but there is dearth need for more empirical studies on this important issue. This paper presents the analysis of technical efficiency of cowpea production in Osun state southwest Nigeria, using the stochastic production frontier, budgetary and resource-use efficiency analyses. The marginal value products of all the resources used are less than their prices (MVPResource-Use Efficiency, Technical Efficiency, Cowpea Production, Stochastic Frontier, Tobit Model and Marginal Products

Pre-emptive resource-constrained multimode project scheduling using genetic algorithm: a dynamic forward approach

Purpose: The issue resource over-allocating is a big concern for project engineers in the process of scheduling project activities. Resource over-allocating drawback is frequently seen after scheduling of a project in practice which causes a schedule to be useless. Modifying an over-allocated schedule is very complicated and needs a lot of efforts and time. In this paper, a new and fast tracking method is proposed to schedule large scale projects which can help project engineers to schedule the project rapidly and with more confidence. Design/methodology/approach: In this article, a forward approach for maximizing net present value (NPV) in multi-mode resource constrained project scheduling problem while assuming discounted positive cash flows (MRCPSP-DCF) is proposed. The progress payment method is used and all resources are considered as pre-emptible. The proposed approach maximizes NPV using unscheduled resources through resource calendar in forward mode. For this purpose, a Genetic Algorithm is applied to solve. Findings: The findings show that the proposed method is an effective way to maximize NPV in MRCPSP-DCF problems while activity splitting is allowed. The proposed algorithm is very fast and can schedule experimental cases with 1000 variables and 100 resources in few seconds. The results are then compared with branch and bound method and simulated annealing algorithm and it is found the proposed genetic algorithm can provide results with better quality. Then algorithm is then applied for scheduling a hospital in practice. Originality/value: The method can be used alone or as a macro in Microsoft Office Project® Software to schedule MRCPSP-DCF problems or to modify resource over-allocated activities after scheduling a project. This can help project engineers to schedule project activities rapidly with more accuracy in practice.Peer Reviewe

Perspectives on Interstellar Dust Inside and Outside of the Heliosphere

Measurements by dust detectors on interplanetary spacecraft appear to indicate a substantial flux of interstellar particles with masses exceeding 10^{-12}gram. The reported abundance of these massive grains cannot be typical of interstellar gas: it is incompatible with both interstellar elemental abundances and the observed extinction properties of the interstellar dust population. We discuss the likelihood that the Solar System is by chance located near an unusual concentration of massive grains and conclude that this is unlikely, unless dynamical processes in the ISM are responsible for such concentrations. Radiation pressure might conceivably drive large grains into "magnetic valleys". If the influx direction of interstellar gas and dust is varying on a ~10 yr timescale, as suggested by some observations, this would have dramatic implications for the small-scale structure of the interstellar medium.Comment: 13 pages. To appear in Space Science Review

Akt/PKB activation and insulin signaling: a novel insulin signaling pathway in the treatment of type 2 diabetes

Type 2 diabetes is a metabolic disease categorized primarily by reduced insulin sensitivity, β-cell dysfunction, and elevated hepatic glucose production. Treatments reducing hyperglycemia and the secondary complications that result from these dysfunctions are being sought after. Two distinct pathways encourage glucose transport activity in skeletal muscle, ie, the contraction-stimulated pathway reliant on Ca2+/5′-monophosphate-activated protein kinase (AMPK)-dependent mechanisms and an insulin-dependent pathway activated via upregulation of serine/threonine protein kinase Akt/PKB. Metformin is an established treatment for type 2 diabetes due to its ability to increase peripheral glucose uptake while reducing hepatic glucose production in an AMPK-dependent manner. Peripheral insulin action is reduced in type 2 diabetics whereas AMPK signaling remains largely intact. This paper firstly reviews AMPK and its role in glucose uptake and then focuses on a novel mechanism known to operate via an insulin-dependent pathway. Inositol hexakisphosphate (IP6) kinase 1 (IP6K1) produces a pyrophosphate group at the position of IP6 to generate a further inositol pyrophosphate, ie, diphosphoinositol pentakisphosphate (IP7). IP7 binds with Akt/PKB at its pleckstrin homology domain, preventing interaction with phosphatidylinositol 3,4,5-trisphosphate, and therefore reducing Akt/PKB membrane translocation and insulin-stimulated glucose uptake. Novel evidence suggesting a reduction in IP7 production via IP6K1 inhibition represents an exciting therapeutic avenue in the treatment of insulin resistance. Metformin-induced activation of AMPK is a key current intervention in the management of type 2 diabetes. However, this treatment does not seem to improve peripheral insulin resistance. In light of this evidence, we suggest that inhibition of IP6K1 may increase insulin sensitivity and provide a novel research direction in the treatment of insulin resistance