940 research outputs found
First documentation of the Polygnathoides siluricus conodont Zone (Ludfordian) in South America (Argentina) and the stratigraphic significance of the younger species of Kockelella (Conodonta)
The coquinoid beds from the middle part of the Los Espejos Formation at the Poblete creek section (Talacasto Creek) yielded abundant conodonts. The genus Kockelella (Walliser) represents the most relevant biostratigraphical genus in this conodont fauna. The co-occurrence of Kockelella maenniki Serpagli and Corradini, Kockelella variabilis ichnusae Serpagli and Corradini, K. variabilis Walliser, Kockelella ortus sardoa (Serpagli & Corradini), and Kockelella ortus absidata (Barrick & Klapper) allow us to record for the first time the Polygnathoides siluricus Zone in South America, which suggests the Ludfordian Stage (late Ludlow). We also propose an accurate correlation of the Los Espejos Formation with the lower Ludfordian deposits from the Carnic Alps, Sardinia, Morocco, Czech Republic, Gotland, and North America.Fil: Gomez, Maria Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan. Centro de Investigaciones de la Geosfera y Biosfera. Universidad Nacional de San Juan. Facultad de Ciencias Exactas Físicas y Naturales. Centro de Investigaciones de la Geosfera y Biosfera; ArgentinaFil: Mestre, Ana Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan. Centro de Investigaciones de la Geosfera y Biosfera. Universidad Nacional de San Juan. Facultad de Ciencias Exactas Físicas y Naturales. Centro de Investigaciones de la Geosfera y Biosfera; ArgentinaFil: Garcias Paez, Yanina Vanesa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan. Centro de Investigaciones de la Geosfera y Biosfera. Universidad Nacional de San Juan. Facultad de Ciencias Exactas Físicas y Naturales. Centro de Investigaciones de la Geosfera y Biosfera; ArgentinaFil: Corradini, Carlo. Università degli Studi di Cagliari; Itali
orbifold compactifications in with Gauss-Bonnet term
We present a general setup for junctions of semi-infinite 4-branes in
with the Gauss-Bonnet term. The 3-brane tension at the junction of 4-branes can
be nonzero. Using the brane junctions as the origin of the discrete
rotation symmetry, we identify 3-brane tensions at three fixed points of the
orbifold in terms of the 4-brane tensions. As a result, the three
3-brane tensions can be simultaneously positive, which enables us to explain
the mass hierarchy by taking one of two branes apart from the hidden brane as
the visible brane, and hence does not introduce a severe cosmological problem.Comment: Latex file of 20 pages including 2 figure
Photon-Graviton Amplitudes from the Effective Action
We report on the status of an ongoing effort to calculate the complete
one-loop low-energy effective actions in Einstein-Maxwell theory with a massive
scalar or spinor loop, and to use them for obtaining the explicit form of the
corresponding M-graviton/N-photon amplitudes. We present explicit results for
the effective actions at the one-graviton four-photon level, and for the
amplitudes at the one-graviton two-photon level. As expected on general
grounds, these amplitudes relate in a simple way to the corresponding
four-photon amplitudes. We also derive the gravitational Ward identity for the
1PI one-graviton -- N photon amplitude.Comment: 9 pages, 2 figures, talk given by C. Schubert at "Supersymmetries and
Quantum Symmetries - SQS`2011", JINR Dubna, July 18 - 23, 2011 (to appear in
the Proceedings
Study of a Nonlocal Density scheme for electronic--structure calculations
An exchange-correlation energy functional beyond the local density
approximation, based on the exchange-correlation kernel of the homogeneous
electron gas and originally introduced by Kohn and Sham, is considered for
electronic structure calculations of semiconductors and atoms. Calculations are
carried out for diamond, silicon, silicon carbide and gallium arsenide. The
lattice constants and gaps show a small improvement with respect to the LDA
results.
However, the corresponding corrections to the total energy of the isolated
atoms are not large enough to yield a substantial improvement for the cohesive
energy of solids, which remains hence overestimated as in the LDA.Comment: 4 postscript figure
Local Unit Invariance, Back-Reacting Tractors and the Cosmological Constant Problem
When physics is expressed in a way that is independent of local choices of
unit systems, Riemannian geometry is replaced by conformal geometry. Moreover
masses become geometric, appearing as Weyl weights of tractors (conformal
multiplets of fields necessary to keep local unit invariance manifest). The
relationship between these weights and masses is through the scalar curvature.
As a consequence mass terms are spacetime dependent for off-shell gravitational
backgrounds, but happily constant for physical, Einstein manifolds.
Unfortunately this introduces a naturalness problem because the scalar
curvature is proportional to the cosmological constant. By writing down tractor
stress tensors (multiplets built from the standard stress tensor and its first
and second derivatives), we show how back-reaction solves this naturalness
problem. We also show that classical back-reaction generates an interesting
potential for scalar fields. We speculate that a proper description of how
physical systems couple to scale, could improve our understanding of
naturalness problems caused by the disparity between the particle physics and
observed, cosmological constants. We further give some ideas how an ambient
description of tractor calculus could lead to a Ricci-flat/CFT correspondence
which generalizes the AdS side of Maldacena's duality to a Ricci-flat space of
one higher dimension.Comment: 20 pages, 2 figure
Prolonged survival in the absence of disease-recurrence in advanced-stage follicular lymphoma following chemo-immunotherapy: 13-year update of the prospective, multicenter randomized GITMO-IIL trial
Aprospective trial conducted in the period 2000-2005 showed no survival advantage for high-dose chemotherapy with rituximab and autograft (RHDS) versus conventional chemotherapy with rituximab (CHOP-R) as firstline therapy in 134 high-risk follicular lymphoma patients aged <60 years. The study has been updated at the 13-year median follow up. As of February 2017, 88 (66%) patients were alive, with overall survival of 66.4% at 13 years, without a significant difference between R-HDS (64.5%) and CHOP-R (68.5%). To date, 46 patients have died, mainly because of disease progression (47.8% of all deaths), secondary malignancies (3 solid tumor, 9 myelodysplasia/acute leukemia; 26.1% of all deaths), and other toxicities (21.7% of all deaths). Complete remission was documented in 98 (73.1%) patients and associated with overall survival, with 13- year estimates of 77.0% and 36.8% for complete remission versus no-complete remission, respectively. Molecular remission was documented in 39 (65%) out of 60 evaluable patients and associated with improved survival. In multivariate analysis, complete remission achievement had the strongest effect on survival (P<0.001), along with younger age (P=0.002) and female sex (P=0.013). Overall, 50 patients (37.3%) survived with no disease recurrence (18 CHOP-R, 32 R-HDS). This follow up is the longest reported on follicular lymphoma treated upfront with rituximab-chemotherapy and demonstrates an unprecedented improvement in survival compared to the pre-rituximab era, regardless of the use of intensified or conventional treatment. Complete remission was the most important factor for prolonged survival and a high proportion of patients had prolonged survival in their first remission, raising the issue of curability in follicular lymphoma
Bulk Axions, Brane Back-reaction and Fluxes
Extra-dimensional models can involve bulk pseudo-Goldstone bosons (pGBs)
whose shift symmetry is explicitly broken only by physics localized on branes.
Reliable calculation of their low-energy potential is often difficult because
it requires details of the stabilization of the extra dimensions. In rugby ball
solutions, for which two compact extra dimensions are stabilized in the
presence of only positive-tension brane sources, the effects of brane
back-reaction can be computed explicitly. This allows the calculation of the
shape of the low-energy pGB potential and response of the extra dimensional
geometry as a function of the perturbing brane properties. If the
pGB-dependence is a small part of the total brane tension a very general
analysis is possible, permitting an exploration of how the system responds to
frustration when the two branes disagree on what the proper scalar vacuum
should be. We show how the low-energy potential is given by the sum of brane
tensions (in agreement with common lore) when only the brane tensions couple to
the pGB. We also show how a direct brane coupling to the flux stabilizing the
extra dimensions corrects this result in a way that does not simply amount to
the contribution of the flux to the brane tensions. We calculate the mass of
the would-be zero mode, and briefly describe several potential applications,
including a brane realization of `natural inflation,' and a dynamical mechanism
for suppressing the couplings of the pGB to matter localized on the branes.
Since the scalar can be light enough to be relevant to precision tests of
gravity (in a technically natural way) this mechanism can be relevant to
evading phenomenological bounds.Comment: 36 pages, JHEP styl
Hydrogels Based on Chitosan and Chitosan Derivatives for Biomedical Applications
Chitosan (CS) is a polymer obtained from chitin, being this, after the cellulose, the most abundant polysaccharide. The fact of (i) CS being obtained from renewable sources; (ii) CS to possess capability for doing interactions with different moieties being such capability dependent of pH; (iii) plenty of possibilities for chemical modification of CS; and (iv) tuning the final properties of CS derivatives makes this polymer very interesting in academic and technological points of view. In this way, hydrogels based on CS and on CS derivatives have been widely used for biomedical applications. Other important technological applications can be also cited, such as adsorbent of metals and dyes in wastewater from industrial effluents. In pharmaceutical field, hydrogels based on CS are often used as drugs’ and proteins’ carrier formulations due to the inherent characteristics such as the biocompatibility, nontoxicity, hydrophilicity, etc. This chapter is an attempt for updating and joining the plenty of available information regarding the preparation, characterization, and biomedical application of hydrogels based on chitosan and chitosan derivatives. More than 260 references are provided, being the majority of them published in the last 10 years
Experimental Probes of the Randall-Sundrum Infinite Extra Dimension
The phenomenological possibilities of the Randall-Sundrum non-compact extra
dimension scenario with the AdS horizon increased to approximately a millimeter
length, corresponding to an effective brane tension of TeV^4, are investigated.
The corrections to the Newtonian potential are found to be the only
observationally accessible probe of this scenario, as previously suggested in
the literature. In particular, the presence of the continuum of KK modes does
not lead to any observable collider signatures. The extent to which
experimental tests of Newtonian gravity can distinguish this scenario from the
scenario of Arkani-Hamed, Dimopoulos, and Dvali with one and two millimeter
size extra dimensions is explicitly demonstrated.Comment: 22 pages, 2 figures, references adde
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