940 research outputs found

    First documentation of the Polygnathoides siluricus conodont Zone (Ludfordian) in South America (Argentina) and the stratigraphic significance of the younger species of Kockelella (Conodonta)

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    The coquinoid beds from the middle part of the Los Espejos Formation at the Poblete creek section (Talacasto Creek) yielded abundant conodonts. The genus Kockelella (Walliser) represents the most relevant biostratigraphical genus in this conodont fauna. The co-occurrence of Kockelella maenniki Serpagli and Corradini, Kockelella variabilis ichnusae Serpagli and Corradini, K. variabilis Walliser, Kockelella ortus sardoa (Serpagli & Corradini), and Kockelella ortus absidata (Barrick & Klapper) allow us to record for the first time the Polygnathoides siluricus Zone in South America, which suggests the Ludfordian Stage (late Ludlow). We also propose an accurate correlation of the Los Espejos Formation with the lower Ludfordian deposits from the Carnic Alps, Sardinia, Morocco, Czech Republic, Gotland, and North America.Fil: Gomez, Maria Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan. Centro de Investigaciones de la Geosfera y Biosfera. Universidad Nacional de San Juan. Facultad de Ciencias Exactas Físicas y Naturales. Centro de Investigaciones de la Geosfera y Biosfera; ArgentinaFil: Mestre, Ana Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan. Centro de Investigaciones de la Geosfera y Biosfera. Universidad Nacional de San Juan. Facultad de Ciencias Exactas Físicas y Naturales. Centro de Investigaciones de la Geosfera y Biosfera; ArgentinaFil: Garcias Paez, Yanina Vanesa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan. Centro de Investigaciones de la Geosfera y Biosfera. Universidad Nacional de San Juan. Facultad de Ciencias Exactas Físicas y Naturales. Centro de Investigaciones de la Geosfera y Biosfera; ArgentinaFil: Corradini, Carlo. Università degli Studi di Cagliari; Itali

    ZNZ_N orbifold compactifications in AdS6AdS_6 with Gauss-Bonnet term

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    We present a general setup for junctions of semi-infinite 4-branes in AdS6AdS_6 with the Gauss-Bonnet term. The 3-brane tension at the junction of 4-branes can be nonzero. Using the brane junctions as the origin of the ZNZ_N discrete rotation symmetry, we identify 3-brane tensions at three fixed points of the orbifold T2/Z3T^2/Z_3 in terms of the 4-brane tensions. As a result, the three 3-brane tensions can be simultaneously positive, which enables us to explain the mass hierarchy by taking one of two branes apart from the hidden brane as the visible brane, and hence does not introduce a severe cosmological problem.Comment: Latex file of 20 pages including 2 figure

    Photon-Graviton Amplitudes from the Effective Action

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    We report on the status of an ongoing effort to calculate the complete one-loop low-energy effective actions in Einstein-Maxwell theory with a massive scalar or spinor loop, and to use them for obtaining the explicit form of the corresponding M-graviton/N-photon amplitudes. We present explicit results for the effective actions at the one-graviton four-photon level, and for the amplitudes at the one-graviton two-photon level. As expected on general grounds, these amplitudes relate in a simple way to the corresponding four-photon amplitudes. We also derive the gravitational Ward identity for the 1PI one-graviton -- N photon amplitude.Comment: 9 pages, 2 figures, talk given by C. Schubert at "Supersymmetries and Quantum Symmetries - SQS`2011", JINR Dubna, July 18 - 23, 2011 (to appear in the Proceedings

    Study of a Nonlocal Density scheme for electronic--structure calculations

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    An exchange-correlation energy functional beyond the local density approximation, based on the exchange-correlation kernel of the homogeneous electron gas and originally introduced by Kohn and Sham, is considered for electronic structure calculations of semiconductors and atoms. Calculations are carried out for diamond, silicon, silicon carbide and gallium arsenide. The lattice constants and gaps show a small improvement with respect to the LDA results. However, the corresponding corrections to the total energy of the isolated atoms are not large enough to yield a substantial improvement for the cohesive energy of solids, which remains hence overestimated as in the LDA.Comment: 4 postscript figure

    Local Unit Invariance, Back-Reacting Tractors and the Cosmological Constant Problem

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    When physics is expressed in a way that is independent of local choices of unit systems, Riemannian geometry is replaced by conformal geometry. Moreover masses become geometric, appearing as Weyl weights of tractors (conformal multiplets of fields necessary to keep local unit invariance manifest). The relationship between these weights and masses is through the scalar curvature. As a consequence mass terms are spacetime dependent for off-shell gravitational backgrounds, but happily constant for physical, Einstein manifolds. Unfortunately this introduces a naturalness problem because the scalar curvature is proportional to the cosmological constant. By writing down tractor stress tensors (multiplets built from the standard stress tensor and its first and second derivatives), we show how back-reaction solves this naturalness problem. We also show that classical back-reaction generates an interesting potential for scalar fields. We speculate that a proper description of how physical systems couple to scale, could improve our understanding of naturalness problems caused by the disparity between the particle physics and observed, cosmological constants. We further give some ideas how an ambient description of tractor calculus could lead to a Ricci-flat/CFT correspondence which generalizes the AdS side of Maldacena's duality to a Ricci-flat space of one higher dimension.Comment: 20 pages, 2 figure

    Prolonged survival in the absence of disease-recurrence in advanced-stage follicular lymphoma following chemo-immunotherapy: 13-year update of the prospective, multicenter randomized GITMO-IIL trial

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    Aprospective trial conducted in the period 2000-2005 showed no survival advantage for high-dose chemotherapy with rituximab and autograft (RHDS) versus conventional chemotherapy with rituximab (CHOP-R) as firstline therapy in 134 high-risk follicular lymphoma patients aged <60 years. The study has been updated at the 13-year median follow up. As of February 2017, 88 (66%) patients were alive, with overall survival of 66.4% at 13 years, without a significant difference between R-HDS (64.5%) and CHOP-R (68.5%). To date, 46 patients have died, mainly because of disease progression (47.8% of all deaths), secondary malignancies (3 solid tumor, 9 myelodysplasia/acute leukemia; 26.1% of all deaths), and other toxicities (21.7% of all deaths). Complete remission was documented in 98 (73.1%) patients and associated with overall survival, with 13- year estimates of 77.0% and 36.8% for complete remission versus no-complete remission, respectively. Molecular remission was documented in 39 (65%) out of 60 evaluable patients and associated with improved survival. In multivariate analysis, complete remission achievement had the strongest effect on survival (P<0.001), along with younger age (P=0.002) and female sex (P=0.013). Overall, 50 patients (37.3%) survived with no disease recurrence (18 CHOP-R, 32 R-HDS). This follow up is the longest reported on follicular lymphoma treated upfront with rituximab-chemotherapy and demonstrates an unprecedented improvement in survival compared to the pre-rituximab era, regardless of the use of intensified or conventional treatment. Complete remission was the most important factor for prolonged survival and a high proportion of patients had prolonged survival in their first remission, raising the issue of curability in follicular lymphoma

    Bulk Axions, Brane Back-reaction and Fluxes

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    Extra-dimensional models can involve bulk pseudo-Goldstone bosons (pGBs) whose shift symmetry is explicitly broken only by physics localized on branes. Reliable calculation of their low-energy potential is often difficult because it requires details of the stabilization of the extra dimensions. In rugby ball solutions, for which two compact extra dimensions are stabilized in the presence of only positive-tension brane sources, the effects of brane back-reaction can be computed explicitly. This allows the calculation of the shape of the low-energy pGB potential and response of the extra dimensional geometry as a function of the perturbing brane properties. If the pGB-dependence is a small part of the total brane tension a very general analysis is possible, permitting an exploration of how the system responds to frustration when the two branes disagree on what the proper scalar vacuum should be. We show how the low-energy potential is given by the sum of brane tensions (in agreement with common lore) when only the brane tensions couple to the pGB. We also show how a direct brane coupling to the flux stabilizing the extra dimensions corrects this result in a way that does not simply amount to the contribution of the flux to the brane tensions. We calculate the mass of the would-be zero mode, and briefly describe several potential applications, including a brane realization of `natural inflation,' and a dynamical mechanism for suppressing the couplings of the pGB to matter localized on the branes. Since the scalar can be light enough to be relevant to precision tests of gravity (in a technically natural way) this mechanism can be relevant to evading phenomenological bounds.Comment: 36 pages, JHEP styl

    Hydrogels Based on Chitosan and Chitosan Derivatives for Biomedical Applications

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    Chitosan (CS) is a polymer obtained from chitin, being this, after the cellulose, the most abundant polysaccharide. The fact of (i) CS being obtained from renewable sources; (ii) CS to possess capability for doing interactions with different moieties being such capability dependent of pH; (iii) plenty of possibilities for chemical modification of CS; and (iv) tuning the final properties of CS derivatives makes this polymer very interesting in academic and technological points of view. In this way, hydrogels based on CS and on CS derivatives have been widely used for biomedical applications. Other important technological applications can be also cited, such as adsorbent of metals and dyes in wastewater from industrial effluents. In pharmaceutical field, hydrogels based on CS are often used as drugs’ and proteins’ carrier formulations due to the inherent characteristics such as the biocompatibility, nontoxicity, hydrophilicity, etc. This chapter is an attempt for updating and joining the plenty of available information regarding the preparation, characterization, and biomedical application of hydrogels based on chitosan and chitosan derivatives. More than 260 references are provided, being the majority of them published in the last 10 years

    Experimental Probes of the Randall-Sundrum Infinite Extra Dimension

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    The phenomenological possibilities of the Randall-Sundrum non-compact extra dimension scenario with the AdS horizon increased to approximately a millimeter length, corresponding to an effective brane tension of TeV^4, are investigated. The corrections to the Newtonian potential are found to be the only observationally accessible probe of this scenario, as previously suggested in the literature. In particular, the presence of the continuum of KK modes does not lead to any observable collider signatures. The extent to which experimental tests of Newtonian gravity can distinguish this scenario from the scenario of Arkani-Hamed, Dimopoulos, and Dvali with one and two millimeter size extra dimensions is explicitly demonstrated.Comment: 22 pages, 2 figures, references adde
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