13,758 research outputs found

    The effect of 1 to 5 keV electrons on the reproductive integrity of microorganisms

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    Microorganisms were exposed to simulated space environment in order to assess the effect of electrons in the energy range 1 to 5 keV on their colony-forming ability. The test system consisted of an electron gun and power supply, a dosimetry subsystem, and a vacuum subsystem. The system was capable of current densities ranging from 0.1 nA/sq cm to 5 micro A/sq cm on a 25 sq on target and an ultimate vacuum of 0.0006 N/sq m (0.000004 torr). The results of the experimental program show a significant reduction in microbial reproductive integrity

    Surface roughness detector Patent

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    Roughness detector for recording surface pattern of irregularitie

    The Loudest Event Statistic: General Formulation, Properties and Applications

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    The use of the loudest observed event to generate statistical statements about rate and strength has become standard in searches for gravitational waves from compact binaries and pulsars. The Bayesian formulation of the method is generalized in this paper to allow for uncertainties both in the background estimate and in the properties of the population being constrained. The method is also extended to allow rate interval construction. Finally, it is shown how to combine the results from multiple experiments and a comparison is drawn between the upper limit obtained in a single search and the upper limit obtained by combining the results of two experiments each of half the original duration. To illustrate this, we look at an example case, motivated by the search for gravitational waves from binary inspiral.Comment: 11 pages, 8 figure

    DSK1, a novel kinesin-related protein from the diatom Cylindrotheca fusiformis that is involved in anaphase spindle elongation.

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    We have identified an 80-kD protein that is involved in mitotic spindle elongation in the diatom Cylindrotheca fusiformis. DSK1 (Diatom Spindle Kinesin 1) was isolated using a peptide antibody raised against a conserved region in the motor domain of the kinesin superfamily. By sequence homology, DSK1 belongs to the central motor family of kinesin-related proteins. Immunoblots using an antibody raised against a non-conserved region of DSK1 show that DSK1 is greatly enriched in mitotic spindle preparations. Anti-DSK1 stains in diatom central spindle with a bias toward the midzone, and staining is retained in the spindle midzone during spindle elongation in vitro. Furthermore, preincubation with anti-DSK1 blocks function in an in vitro spindle elongation assay. This inhibition of spindle elongation can be rescued by preincubating concurrently with the fusion protein against which anti-DSK1 was raised. We conclude that DSK1 is involved in spindle elongation and is likely to be responsible for pushing hal-spindles apart in the spindle midzone

    Influence of training history and contraction velocity on hamstring muscle coactivation during maximal effort knee extension

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    When a muscle produces voluntary force, muscles on the opposite side of the joint, the antagonists, are also activated. While coactivation of the knee flexors during knee extension is presumed to increase joint stability by decreasing anterior shear force of the tibia on the femur, the coactivation of the hamstrings also produces what is called the antagonist torque. Systematic exercise in the form of resistance training can reduce antagonist muscle coactivation in healthy young adults. However, the mechanical consequence of this neurological adaptation is unclear. We thus hypothesized that previously strength-trained individuals would exhibit less antagonist coactivation, resulting in a reduced antagonist torque, and that with an increase in contraction speed there would be an increase in antagonist coactivation to slow the movement but there would be less of an increase due to speed in the trained compared with untrained individuals. Therefore, the purpose of this study was to determine the effects of training status on coactivation, i.e., antagonist torque, and on the speed-sensitivity of coactivation. Subjects for this study were fitted with surface EMG electrodes on their thigh muscles, and performed maximal effort knee extensions on a dynamometer, using shortening (concentric) and lengthening (eccentric) contractions at 30, 90, and 150°/s. As expected, trained individuals produced ~44% less coactivation at all contractions speeds. Against the hypothesis, coactivation did not increase in either group as velocity increased, as there was less than 10% difference in coactivation levels between the 3 speeds. Also against the hypothesis, as determined with an EMG-driven mathematical model, antagonist torque did not decrease with decreasing coactivation; in fact we see a trend towards the opposite for trained individuals. A borderline greater antagonist torque was noted in the trained compared to the untrained subjects even with decreased coactivation of the trained. These data suggest that antagonist muscle coactivation is less in trained healthy young adults but this reduced neural activation does not manifest itself in lower levels of antagonist torque. Therefore, leg strength training may increase muscle strength in part by reducing antagonist muscle coactivation without compromising joint stability.  M.S

    Reduced chemistry for butanol isomers at engine-relevant conditions

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    Butanol has received significant research attention as a second-generation biofuel in the past few years. In the present study, skeletal mechanisms for four butanol isomers were generated from two widely accepted, well-validated detailed chemical kinetic models for the butanol isomers. The detailed models were reduced using a two-stage approach consisting of the directed relation graph with error propagation and sensitivity analysis. During the reduction process, issues were encountered with pressure-dependent reactions formulated using the logarithmic pressure interpolation approach; these issues are discussed and recommendations made to avoid ambiguity in its future implementation in mechanism development. The performance of the skeletal mechanisms generated here was compared with that of detailed mechanisms in simulations of autoignition delay times, laminar flame speeds, and perfectly stirred reactor temperature response curves and extinction residence times, over a wide range of pressures, temperatures, and equivalence ratios. The detailed and skeletal mechanisms agreed well, demonstrating the adequacy of the resulting reduced chemistry for all the butanol isomers in predicting global combustion phenomena. In addition, the skeletal mechanisms closely predicted the time-histories of fuel mass fractions in homogeneous compression-ignition engine simulations. The performance of each butanol isomer was additionally compared with that of a gasoline surrogate with an antiknock index of 87 in a homogeneous compression-ignition engine simulation. The gasoline surrogate was consumed faster than any of the butanol isomers, with tert-butanol exhibiting the slowest fuel consumption rate. While n-butanol and isobutanol displayed the most similar consumption profiles relative to the gasoline surrogate, the two literature chemical kinetic models predicted different orderings.Comment: 39 pages, 16 figures. Supporting information available via https://doi.org/10.1021/acs.energyfuels.6b0185

    Roman Banditry: Scorning Senatorial Skullduggery in Sallust

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    Coarsening of Fine-Scale Exsolution Lamellae

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    Diffusional exchange between the wedge-shaped terminations of fine-scale, coherent exsolution lamellae and the large flat sides of adjacent like lamellae is proposed as the principal mechanism for the coarsening of lamellar exsolution textures in silicate minerals. Following the methods of Gibbs (1906), a formula is derived for the chemical potential gradients due to interfacial energy effects that drive the proposed diffusion and coarsening...

    A Longitudinal Study on the Drivers of Forestation

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    This paper studies the effects of population growth, income levels, and governance on forestation using longitudinal data covering 161 countries from 1996-2015. The study begins with a review of the empirical literature on deforestation and preservation of environmental quality. Then, we conduct our own empirical analysis through log differencing and analysis of annual percentage changes in forest area. We find evidence that these factors matter, but that the relationships are weak. The estimated effects do differ between our groupings of countries with regard to income levels as well as forest area sizes. Population growth generally leads to a reduction in forest area. Conversely, rising incomes slow deforestation and increase the chances of reforestation and afforestation. We witness the disappearance of a Kuznets curve relationship across all groups after individual country effects are included. A bettering of perceived rule of law, political stability, and reduction in corruption is also correlated with more positive forestation rates
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