Social variety in the yellow bellied marmot: a population behavioural system.

This is the publisher's version, which can also be found at: http://www.sciencedirect.com/science/article/pii/000334727790108

Evidence for universality in the initial planetesimal mass function

Planetesimals may form from the gravitational collapse of dense particle clumps initiated by the streaming instability. We use simulations of aerodynamically coupled gas-particle mixtures to investigate whether the properties of planetesimals formed in this way depend upon the sizes of the particles that participate in the instability. Based on three high resolution simulations that span a range of dimensionless stopping time $6 \times 10^{-3} \leq \tau \leq 2$ no statistically significant differences in the initial planetesimal mass function are found. The mass functions are fit by a power-law, ${\rm d}N / {\rm d}M_p \propto M_p^{-p}$, with $p=1.5-1.7$ and errors of $\Delta p \approx 0.1$. Comparing the particle density fields prior to collapse, we find that the high wavenumber power spectra are similarly indistinguishable, though the large-scale geometry of structures induced via the streaming instability is significantly different between all three cases. We interpret the results as evidence for a near-universal slope to the mass function, arising from the small-scale structure of streaming-induced turbulence.Comment: 7 pages, 4 figures, accepted to ApJ Letters after minor modifications, including two new figures and some new text that better clarify our result

Lifetime cost effectiveness of simvastatin in a range of risk groups and age groups derived from a randomised trial of 20,536 people

<i>Objectives</i>: To evaluate the cost effectiveness of 40 mg simvastatin daily continued for life in people of different ages with differing risks of vascular disease. Design A model developed from a randomised trial was used to estimate lifetime risks of vascular events and costs of treatment and hospital admissions in the United Kingdom. <i>Setting</i>: 69 hospitals in the UK. <i>Participants</i>: 20 536 men and women (aged 40-80) with coronary disease, other occlusive arterial disease, or diabetes. <i>Interventions</i>: 40 mg simvastatin daily versus placebo for an average of 5 years. <i>Main</i> <i>outcome</i> <i>measures</i>: Cost effectiveness of 40 mg simvastatin daily expressed as additional cost per life year gained. Major vascular event defined as non-fatal myocardial infarction or death from coronary disease, any stroke, or revascularisation procedure. Results were extrapolated to younger and older age groups at lower risk of vascular disease than were studied directly, as well as to lifetime treatment. <i>Results</i>: At the April 2005 UK price of £4.87 (€7; $9) per 28 day pack of generic 40 mg simvastatin, lifetime treatment was cost saving in most age groups and vascular disease risk groups studied directly. Gains in life expectancy and cost savings decreased with increasing age and with decreasing risk of vascular disease. People aged 40-49 with 5 year risks of major vascular events of 42% and 12% at start of treatment gained 2.49 and 1.67 life years, respectively. Treatment with statins remained cost saving or cost less than £2500 per life year gained in people as young as 35 years or as old as 85 with 5 year risks of a major vascular event as low as 5% at the start of treatment. <i>Conclusions</i>: Treatment with statins is cost effective in a wider population than is routinely treated at present

Transient LTRE analysis reveals the demographic and trait-mediated processes that buffer population growth.

Temporal variation in environmental conditions affects population growth directly via its impact on vital rates, and indirectly through induced variation in demographic structure and phenotypic trait distributions. We currently know very little about how these processes jointly mediate population responses to their environment. To address this gap, we develop a general transient life table response experiment (LTRE) which partitions the contributions to population growth arising from variation in (1) survival and reproduction, (2) demographic structure, (3) trait values and (4) climatic drivers. We apply the LTRE to a population of yellow-bellied marmots (Marmota flaviventer) to demonstrate the impact of demographic and trait-mediated processes. Our analysis provides a new perspective on demographic buffering, which may be a more subtle phenomena than is currently assumed. The new LTRE framework presents opportunities to improve our understanding of how trait variation influences population dynamics and adaptation in stochastic environments

Heritage, pride and place: exploring the contribution of World Heritage Site status to Liverpool’s sense of place and future development

The report considers opportunities and challenges for Liverpool to make the most of its World Heritage Site (WHS) designation, building on the methodologies applied within the Impacts 08 programme to assess the multiple impacts of large-scale cultural interventions. The analysis focuses primarily on the impact of the WHS designation on the image and reputation of Liverpool, as well as on local citizens’ sense of place. Whilst acknowledging findings from previous reports commissioned by English Heritage in relation to the possible impact of development on the Liverpool World Heritage Site’s ‘Outstanding Universal Value’, this study also explores the socio-cultural, economic and political impact of the designation and management of the WHS on the city and its residents