Effect of N,N-dimethyl-p-methoxyphenylethylamine on blood pressure and brain catecholamines in doca-saline hypertensive rats

Intraperitoneal and intraventricular injections of N,N-dimethyl-p-methoxyphenyl ethylamine (PMPEA) decreased blood pressure in conscious DOCA-saline hypertensive rats. Bilateral injection of this agent into the nucleus tractus solitarii (NTS) of anaesthetized normotensive rats also caused a decrease in blood pressure. The increased turnover of noradrenaline in the dorsal part of the caudal medulla oblongata in DOCA-saline hypertensive rats was found to be restored to normal following treatment with N,N-dimethyl PMPEA. The data indicate a central site of action for the antihypertensive effect of N,N-dimethyl PMPEA

Cermets a base de TiB2: Etude physico-chimique et frittage avec phase liquide

SIGLEAvailable from INIST (FR), Document Supply Service, under shelf-number : TD 83965 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc