Catering to the needs of an aging workforce : the role of employee age in the relationship between corporate social responsibility and employee satisfaction.

Contemporary organizations often reciprocate to society for using resources and for affecting stakeholders by engaging in corporate social responsibility (CSR). It has been shown that CSR has a positive impact on employee attitudes. However, not all employees may react equally strongly to CSR practices. Based on socio-emotional selectivity theory (Carstensen in Science 312:1913–1915, 2006), we contend that the effect of CSR on employee satisfaction will be more pronounced for older than for younger employees, because CSR practices address those emotional needs and goals that are prioritized when people’s future time perspective decreases. In one multi-source field study (N = 143) and one experimental study (N = 500), we demonstrate that CSR indeed has a stronger positive effect on employee satisfaction for older relative to younger employees. Accordingly, engaging in CSR can be an attractive tool for organizations that aim to keep their aging workforce satisfied with their job

Multiscale modelling and simulation, 13th international workshop

Multiscale Modelling and Simulation (MMS) is a cornerstone in the today's research in computational science. Simulations containing multiple models, with each model operating at a different temporal or spatial scale, are a challenging setting that frequently require innovative approaches in areas such as scale bridging, code deployment, error quantification, and scientific analysis. The aim of the MMS workshop is to encourage and consolidate the progress in this multidisciplinary research field, both in the areas of the scientific applications and the underlying infrastructures that enable these applications. Here we briefly introduce the scope of the workshop and highlight some of the key aspects of this year's submissions

Factors predicting 6-month retention among people with opioid use disorders accessing outpatient methadone maintenance therapy in Tshwane, South Africa

Background. In South Africa (SA), increasing illicit opioid use and associated health challenges can be managed with opioid substitution therapy (OST), such as methadone, if the recommended dose and duration of use are prescribed. The Community Oriented Substance Use Programme (COSUP) provides free methadone to patients with opioid use disorder in Tshwane, SA, on need-based criteria.Objectives. To determine selected sociodemographic and substance use treatment factors associated with retention for at least 6 months among participants receiving methadone as part of OST in COSUP.Methods. This was a retrospective cohort study using secondary data of patients treated with methadone at 8 COSUP sites. The factors associated with at least 6 months’ retention for 575 participants from December 2016 to September 2018 were analysed.Results. There were 91.3% males, 86.4% South Africans and 85.9% black Africans, with a median age of 30 years. At baseline, the majority were injecting heroin (55.5%) and were provided with free methadone (59.3%). The median dose of methadone at 6 months or on leaving the programme was 20 mg; 38.4% of participants were retained for at least 6 months. Of those not retained, the median duration on methadone was 56 days, whereas for those retained for at least 6 months, the median number of days on methadone were 254. After adjusting for sex and age, participants receiving methadone doses <50 mg had lower odds of being retained (0 - 20 mg: adjusted odds ratio (aOR) 0.25; p=0.002; 95% confidence interval (CI) 0.10 - 0.61; >20 - 40 mg: aOR 0.20; p<0.001; 95% CI 0.08 - 0.49) than those administered ≥50 mg. Participants who received free methadone had 3.75 the odds of being retained than those buying it themselves (p<0.001; 95% CI 2.47 - 5.70). Participants treated in the inner city had 5.19 the odds of being retained than those in a suburban setting (p<0.001; 95% CI 2.99 - 9.03). Compared with black African participants, white participants had 3.39 the odds of being retained (p=0.001; 95% CI 1.64 - 7.00). Injecting heroin users had 0.63 the odds of being retained (p=0.032; 95% CI 0.41 - 0.96).Conclusions. To maximise retention on OST, methadone should be free, with maintenance doses >50 mg. Reasons for lower retention among participants from periurban settings, those who inject and those from previously disadvantaged racial groups need to be explored, and findings used to inform programming

Historical Contingency in Microbial Resilience to Hydrologic Perturbations

Development of reliable biogeochemical models requires a mechanistic consideration of microbial interactions with hydrology. Microbial response to and its recovery after hydrologic perturbations (i.e., resilience) is a critical component to understand in this regard, but generally difficult to predict because the impacts of future events can be dependent on the history of perturbations (i.e., historical contingency). Fundamental issues underlying this phenomenon include how microbial resilience to hydrologic perturbations is influenced by historical contingency and how their relationships vary depending on the characteristics of microbial functions. To answer these questions, we considered a simple microbial community composed of two species that redundantly consume a common substrate but specialize in producing distinct products and developed a continuous flow reactor model where the two species grow with trade-offs along the flow rate. Simulations of this model revealed that (1) the history of hydrologic perturbations can lead to the shifts in microbial populations, which consequently affect the community’s functional dynamics, and (2) while historical contingency in resilience was consistently predicted for all microbial functions, it was more pronounced for specialized functions, compared to the redundant function. As a signature of historical contingency, our model also predicted the emergence of hysteresis in the transitions across conditions, a critical aspect that can affect transient formation of intermediate compounds in biogeochemistry. This work presents microbial growth traits and their functional redundancy or specialization as fundamental factors that control historical contingencies in resilience

Primary skeletal muscle cells cultured on gelatin bead microcarriers develop structural and biochemical features characteristic of adult skeletal muscle

A primary skeletal muscle cell culture, in which myoblasts derived from newborn rabbit hindlimb muscles grow on gelatin bead microcarriers in suspension and differentiate into myotubes, has been established previously. In the course of differentiation and beginning spontaneous contractions, these multinucleated myotubes do not detach from their support. Here, we describe the development of the primary myotubes with respect to their ultrastructural differentiation. Scanning electron microscopy reveals that myotubes not only grow around the surface of one carrier bead but also attach themselves to neighbouring carriers, forming bridges between carriers. Transmission electron microscopy demonstrates highly ordered myofibrils, T-tubules and sarcoplasmic reticulum. The functionality of the contractile apparatus is evidenced by contractile activity that occurs spontaneously or can be elicited by electrostimulation. Creatine kinase activity increases steadily until day 20 of culture. Regarding the expression of isoforms of myosin heavy chains (MHC), we could demonstrate that from day 16 on, no non-adult MHC isoform mRNAs are present. Instead, on day 28 the myotubes express predominantly adult fast MHCIId/x mRNA and protein. This MHC pattern resembles that of fast muscles of adult rabbits. In contrast, primary myotubes grown on matrigel-covered culture dishes express substantial amounts of non-adult MHC protein even on day 21. To conclude, primary myotubes grown on microcarriers in their later stages exhibit many features of adult skeletal muscle and characteristics of fast type II fibers. Thus, the culture represents an excellent model of adult fast skeletal muscle, for example when investigating molecular mechanisms of fast-to-slow fiber type transformatio

A Rede Guarani/Serra Geral em Santa Catarina e o Programa Nacional de Águas Subterrâneas

A REDE GUARANI/SERRA GERAL é um projeto interinstitucional e interdisciplinar que congrega cientistas, pesquisadores, educadores ambientais, juristas, universidades, fundações, agências governamentais nacionais e internacionais, abarcando a região sul do Brasil. Seu objetivo é a produção de conhecimento compartilhado sobre a gestão sustentável das águas superficiais e subterrâneas, além da elaboração de um modelo jurídico legal e de gestão para o uso e conservação do Sistema Aqüífero Integrado Guarani/Serra Geral (SAIG/SG). Em Santa Catarina, a REDE conta com recursos do CT/Hidro/ANA/CNPq e da FAPESC, bem como de Emenda Coletiva da Bancada Parlamentar catarinense em Brasília, e tem como executor a FUNJAB (Fundação José Arthur Boiteux, da UFSC). As diversas metas e seus componentes estão sob a responsabilidade da UNIPLAC (Universidade do Planalto Catarinense), da UNOESC (Universidade do Oeste de Santa Catarina) e da UFSC (Universidade Federal de Santa Catarina), contando ainda com a participação de pesquisadores da UDESC (Universidade do Estado de Santa Catarina), da EPAGRI (Empresa de Pesquisa Agropecuária e Extensão Rural de Santa Catarina S.A.) e da Universidade de Sevilha, na Espanha, além de outros colaboradores. O Sistema Aqüífero Integrado Guarani/Serra Geral (SAIG/SG) (SCHEIBE, 2006) é a principal fonte de águas subterrâneas das regiões oeste dos estados de Santa Catarina e do Paraná, e norte-noroeste do Rio Grande do Sul

Epistemic and Ontic Quantum Realities

Quantum theory has provoked intense discussions about its interpretation since its pioneer days. One of the few scientists who have been continuously engaged in this development from both physical and philosophical perspectives is Carl Friedrich von Weizsaecker. The questions he posed were and are inspiring for many, including the authors of this contribution. Weizsaecker developed Bohr's view of quantum theory as a theory of knowledge. We show that such an epistemic perspective can be consistently complemented by Einstein's ontically oriented position