The jet-ISM interaction in the Outer Filament of Centaurus A

The interaction between the radio plasma ejected by the active nucleus of a galaxy and the surrounding medium is a key process that can have a strong impact on the interstellar medium of the galaxy and hence on galaxy evolution. The closest laboratory where we can observe and investigate this phenomenon is the radio galaxy Centaurus A. About 15 kpc north-east of this galaxy, a particularly complex region is found: the so-called Outer Filament where jet-cloud interactions have been proposed to occur. We investigate the presence of signatures of jet-ISM interaction by a detailed study of the kinematics of the ionized gas, expanding on previous results obtained from the HI. We observed two regions of the outer filament with VLT/VIMOS in the IFU observing mode. Emission from Hbeta and [OIII]4959,5007\AA\ is detected in both pointings. We found two distinct kinematical components of ionized gas that well match the kinematics of the nearby HI cloud. One component follows the regular kinematics of the rotating gas while the second shows similar velocities to those of the nearby HI component thought to be disturbed by an interaction with the radio jet. We suggest that the ionized and atomic gas are part of the same dynamical gas structure originating as result of the merger that shaped Centaurus A and which is regularly rotating around Centaurus A as proposed by other authors. The gas (ionized and HI) with anomalous velocities is tracing the interaction of the Large-Scale radio Jet with the ISM, suggesting that, although poorly collimated as structure, the jet is still active. However, we can exclude that a strong shock is driving the ionization of the gas. It is likely that a combination of jet entrainment and photoionization by the UV continuum from the central engine is needed in order to explain both the ionization and the kinematics of the gas in the Outer Filament.Comment: 6 pages, 6 figures, 1 table. Final version accepted for publication on A&

The outer filament of Centaurus A as seen by MUSE

We investigate signatures of a jet-interstellar medium (ISM) interaction using optical integral-field observations of the so-called outer filament near Centaurus A, expanding on previous results obtained on a more limited area. Using the Multi Unit Spectroscopic Explorer (MUSE) on the VLT during science verification, we observed a significant fraction of the brighter emitting gas across the outer filament. The ionized gas shows complex morphology with compact blobs, arc-like structures and diffuse emission. Based on the kinematics, we identified three main components. The more collimated component is oriented along the direction of the radio jet. The other two components exhibit diffuse morphology together with arc-like structures also oriented along the radio jet direction. Furthermore, the ionization level of the gas is found to decrease from the more collimated component to the more diffuse components. The morphology and velocities of the more collimated component confirm our earlier results that the outer filament and the nearby HI cloud are likely partially shaped by the lateral expansion of the jet. The arc-like structures embedded within the two remaining components are the clearest evidence of a smooth jet-ISM interaction along the jet direction. This suggests that, although poorly collimated, the radio jet is still active and has an impact on the surrounding gas. This result indicates that the effect on the ISM of even low-power radio jets should be considered when studying the influence Active Galactic Nuclei can have on their host galaxy.Comment: 5 pages, 3 figures, Accepted for publication by A&

Adiabatic dynamics in a spin-1 chain with uniaxial single-spin anisotropy

We study the adiabatic quantum dynamics of an anisotropic spin-1 XY chain across a second order quantum phase transition. The system is driven out of equilibrium by performing a quench on the uniaxial single-spin anisotropy, that is supposed to vary linearly in time. We show that, for sufficiently large system sizes, the excess energy after the quench admits a non trivial scaling behavior that is not predictable by standard Kibble-Zurek arguments for isolated critical points or extended critical regions. This emerges from a competing effect of many accessible low-lying excited states, inside the whole continuous line of critical points.Comment: 17 pages, 8 figures, published versio

Inhibition of Friend erythroleukaemia-cell tumours in vivo by a synthetic analogue of prostaglandin E2.

The effect of 16,16-dimethyl-PGE2-methyl ester (di-M-PGE2), a long-acting synthetic analogue of prostaglandin E2, on the replication of Friend erythroleukaemia cells (FLC) in vivo has been studied. Pre-treatment in vitro of both undifferentiated and differentiated FLC with di-M-PGE2 (1 microgram/ml) did not alter rates of tumour appearance or growth, but increased the median survival of DBA/2J mice. Systemic administration of di-M-PGE2 (10 microgram/mouse/day) was not toxic to the mice, but significantly inhibited tumour growth and increased median survival in mice injected s.c. with undifferentiated FLC. These effects of di-M-PGE2 were much more pronounced in mice receiving differentiated (DMSO-treated) FLC. In this latter group, the appearance of tumour was also significantly delayed by di-M-PGE2. The different effects of di-M-PGE2 treatment on tumours derived from undifferentiated and differentiated cells suggest that the analogue is acting directly on tumour-cell replication rather than on factors related to the host response

Extravehicular activities limitations study. Volume 1: Physiological limitations to extravehicular activity in space

This report contains the results of a comprehensive literature search on physiological aspects of EVA. Specifically, the topics covered are: (1) Oxygen levels; (2) Optimum EVA work; (3) Food and Water; (4) Carbon dioxide levels; (5) Repetitive decompressions; (6) Thermal, and (7) Urine collection. The literature was assessed on each of these topics, followed by statements on conclusions and recommended future research needs

Convergence of Quantum Annealing with Real-Time Schrodinger Dynamics

Convergence conditions for quantum annealing are derived for optimization problems represented by the Ising model of a general form. Quantum fluctuations are introduced as a transverse field and/or transverse ferromagnetic interactions, and the time evolution follows the real-time Schrodinger equation. It is shown that the system stays arbitrarily close to the instantaneous ground state, finally reaching the target optimal state, if the strength of quantum fluctuations decreases sufficiently slowly, in particular inversely proportionally to the power of time in the asymptotic region. This is the same condition as the other implementations of quantum annealing, quantum Monte Carlo and Green's function Monte Carlo simulations, in spite of the essential difference in the type of dynamics. The method of analysis is an application of the adiabatic theorem in conjunction with an estimate of a lower bound of the energy gap based on the recently proposed idea of Somma et. al. for the analysis of classical simulated annealing using a classical-quantum correspondence.Comment: 6 pages, minor correction

Iterative Approximate Consensus in the presence of Byzantine Link Failures

This paper explores the problem of reaching approximate consensus in synchronous point-to-point networks, where each directed link of the underlying communication graph represents a communication channel between a pair of nodes. We adopt the transient Byzantine link failure model [15, 16], where an omniscient adversary controls a subset of the directed communication links, but the nodes are assumed to be fault-free. Recent work has addressed the problem of reaching approximate consen- sus in incomplete graphs with Byzantine nodes using a restricted class of iterative algorithms that maintain only a small amount of memory across iterations [22, 21, 23, 12]. However, to the best of our knowledge, we are the first to consider approximate consensus in the presence of Byzan- tine links. We extend our past work that provided exact characterization of graphs in which the iterative approximate consensus problem in the presence of Byzantine node failures is solvable [22, 21]. In particular, we prove a tight necessary and sufficient condition on the underlying com- munication graph for the existence of iterative approximate consensus algorithms under transient Byzantine link model. The condition answers (part of) the open problem stated in [16].Comment: arXiv admin note: text overlap with arXiv:1202.609

Effect of endogenous and exogenous prostaglandin E on Friend erythroleukaemia cell growth and differentiation.

The effect of exogenous and endogenous prostaglandins on the patterns of growth and differentiation of Friend erythroleukaemia cells (FLC) were studied. During the differentiation process, DMSO stimulated PGE synthesis by an average of 95%. The addition of a long-acting synthetic analogue of PGE2,16,16-dimethyl-PGE2-methyl ester (di-M-PGE2) to the culture medium only slightly and temporarily slowed cell growth, with no appreciable induction of differentiation. However, in the presence of DMSO, the same concentration of di-M-PGE2 produced 73% inhibition of cell growth and accelerated and potently stimulated haemoglobin production. The action of both di-M-PGE2 and DMSO on cell proliferation was dependent upon the state of cell growth at the time of the administration of these compounds. FLC cultures treated with DMSO + di-M-PGE2 produced considerable amounts of haemoglobin before even one duplication cycle was completed. Both DMSO and di-M-PGE2 stimulated endogenous PGE biosynthesis, and the biosynthetic effect of these compounds was synergistic. Inhibition of endogenous prostaglandin synthesis by indomethacin completely abolished the effects produced by DMSO + di-M-PGE2 on the growth, and substantially reduced the stimulated differentiation of FLC. These data suggest that an endogenously synthesized prostaglandin plays a significant role in both the inhibition of replication and in the stimulation of differentiation induced by DMSO and di-M-PGE2 in Friend erythroleukaemia cells