1,374 research outputs found

    ClassCut for Unsupervised Class Segmentation

    Get PDF
    Abstract. We propose a novel method for unsupervised class segmentation on a set of images. It alternates between segmenting object instances and learning a class model. The method is based on a segmentation energy defined over all images at the same time, which can be optimized efficiently by techniques used before in interactive segmentation. Over iterations, our method progressively learns a class model by integrating observations over all images. In addition to appearance, this model captures the location and shape of the class with respect to an automatically determined coordinate frame common across images. This frame allows us to build stronger shape and location models, similar to those used in object class detection. Our method is inspired by interactive segmentation methods [1], but it is fully automatic and learns models characteristic for the object class rather than specific to one particular object/image. We experimentally demonstrate on the Caltech4, Caltech101, and Weizmann horses datasets that our method (a) transfers class knowledge across images and this improves results compared to segmenting every image independently; (b) outperforms Grabcut [1] for the task of unsupervised segmentation; (c) offers competitive performance compared to the state-of-the-art in unsupervised segmentation and in particular it outperforms the topic model [2].

    Comprehensive study of ULF upstream waves observed in the topside ionosphere by CHAMP and on the ground

    Get PDF
    Based on magnetic field measurements from the satellite CHAMP, a detailed picture could be obtained of the upstream wave (UW) distribution in the topside ionosphere. The low, near-polar orbit of CHAMP, covering all local times, allows the global distribution of this type of pulsation to be revealed. The observations from space are compared to recordings of the ground-based MM100 meridional array covering the latitude range 66° to 42° in magnetic coordinates. UWs show up very clearly in the compressional component of the satellite magnetic field data, whereas on the ground, their signature is found in the H component, but it is mixed with oscillations from field line resonant pulsations. Here we first introduce a procedure for an automated detection of UW signatures, both in ground and space data. Then a statistical analysis is presented of UW pulsations recorded during a 132-day period, centred on the autumn 2001 equinox. Observations in the top-side ionosphere reveal a clear latitudinal distribution of the amplitudes. Largest signals are observed at the equator. Minima show up at about 40° latitude. The coherence between ground and satellite wave signatures is high over wide latitude and longitude ranges. We make suggestions about the entry mechanism of UWs from the foreshock region into the magnetosphere. The clear UW signature in satellite recordings between −60° and 60° latitude allows for detailed investigations of the dependence on solar wind conditions. We test the control of solar wind speed, interplanetary magnetic field strength and cone angle on UWs. For the first time, it is possible to derive details of the Doppler-shift effect by modifying the UW frequency from direct observations. The results reconcile foreshock wave generation predictions with near-Earth observations

    PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks

    Get PDF
    Post-translational histone modifications and chromatin remodelling play a critical role controlling the integrity of the genome. Here, we identify histone lysine demethylase PHF2 as a novel regulator of the DNA damage response by regulating DNA damage-induced focus formation of 53BP1 and BRCA1, critical factors in the pathway choice for DNA double strand break repair. PHF2 knockdown leads to impaired BRCA1 focus formation and delays the resolution of 53BP1 foci. Moreover, irradiation-induced RPA phosphorylation and focus formation, as well as localization of CtIP, required for DNA end resection, to sites of DNA lesions are affected by depletion of PHF2. These results are indicative of a defective resection of double strand breaks and thereby an impaired homologous recombination upon PHF2 depletion. In accordance with these data, Rad51 focus formation and homology-directed double strand break repair is inhibited in cells depleted for PHF2. Importantly, we demonstrate that PHF2 knockdown decreases CtIP and BRCA1 protein and mRNA levels, an effect that is dependent on the demethylase activity of PHF2. Furthermore, PHF2-depleted cells display genome instability and are mildly sensitive to the inhibition of PARP. Together these results demonstrate that PHF2 promotes DNA repair by homologous recombination by controlling CtIP-dependent resection of double strand breaks.España Ministerio de Ciencia e Innovacion SAF2016-80626-REspaña, Fundación Canaria Instituto de Investigación Sanitaria de Canarias (FIISC) [PIFUN16/18

    Nonequilibrium effects due to charge fluctuations in intrinsic Josephson systems

    Full text link
    Nonequilibrium effects in layered superconductors forming a stack of intrinsic Josephson junctions are investigated. We discuss two basic nonequilibrium effects caused by charge fluctuations on the superconducting layers: a) the shift of the chemical potential of the condensate and b) charge imbalance of quasi-particles, and study their influence on IV-curves and the position of Shapiro steps.Comment: 17 pages, 2 figures, revised version slightly shortene

    Charge-imbalance effects in intrinsic Josephson systems

    Full text link
    We report on two types of experiments with intrinsic Josephson systems made from layered superconductors which show clear evidence of nonequilibrium effects: 1. In 2-point measurements of IV-curves in the presence of high- frequency radiation a shift of the voltage of Shapiro steps from the canonical value hf/(2e) has been observed. 2. In the IV-curves of double-mesa structures an influence of the current through one mesa on the voltage measured on the other mesa is detected. Both effects can be explained by charge-imbalance on the superconducting layers produced by the quasi-particle current, and can be described successfully by a recently developed theory of nonequilibrium effects in intrinsic Josephson systems.Comment: 8pages, 9figures, submitted to Phys. Rev.

    Shape and structure of N=Z 64Ge; Electromagnetic transition rates from the application of the Recoil Distance Method to knock-out reaction

    Get PDF
    Transition rate measurements are reported for the first and the second 2+ states in N=Z 64Ge. The experimental results are in excellent agreement with large-scale Shell Model calculations applying the recently developed GXPF1A interactions. Theoretical analysis suggests that 64Ge is a collective gamma-soft anharmonic vibrator. The measurement was done using the Recoil Distance Method (RDM) and a unique combination of state-of-the-art instruments at the National Superconducting Cyclotron Laboratory (NSCL). States of interest were populated via an intermediate-energy single-neutron knock-out reaction. RDM studies of knock-out and fragmentation reaction products hold the promise of reaching far from stability and providing lifetime information for excited states in a wide range of nuclei

    Temperature dependence of the charge carrier mobility in gated quasi-one-dimensional systems

    Full text link
    The many-body Monte Carlo method is used to evaluate the frequency dependent conductivity and the average mobility of a system of hopping charges, electronic or ionic on a one-dimensional chain or channel of finite length. Two cases are considered: the chain is connected to electrodes and in the other case the chain is confined giving zero dc conduction. The concentration of charge is varied using a gate electrode. At low temperatures and with the presence of an injection barrier, the mobility is an oscillatory function of density. This is due to the phenomenon of charge density pinning. Mobility changes occur due to the co-operative pinning and unpinning of the distribution. At high temperatures, we find that the electron-electron interaction reduces the mobility monotonically with density, but perhaps not as much as one might intuitively expect because the path summation favour the in-phase contributions to the mobility, i.e. the sequential paths in which the carriers have to wait for the one in front to exit and so on. The carrier interactions produce a frequency dependent mobility which is of the same order as the change in the dc mobility with density, i.e. it is a comparably weak effect. However, when combined with an injection barrier or intrinsic disorder, the interactions reduce the free volume and amplify disorder by making it non-local and this can explain the too early onset of frequency dependence in the conductivity of some high mobility quasi-one-dimensional organic materials.Comment: 9 pages, 8 figures, to be published in Physical Review

    Observation of isotonic symmetry for enhanced quadrupole collectivity in neutron-rich 62,64,66Fe isotopes at N=40

    Full text link
    The transition rates for the 2_{1}^{+} states in 62,64,66Fe were studied using the Recoil Distance Doppler-Shift technique applied to projectile Coulomb excitation reactions. The deduced E2 strengths illustrate the enhanced collectivity of the neutron-rich Fe isotopes up to N=40. The results are interpreted by the generalized concept of valence proton symmetry which describes the evolution of nuclear structure around N=40 as governed by the number of valence protons with respect to Z~30. The deformation suggested by the experimental data is reproduced by state-of-the-art shell calculations with a new effective interaction developed for the fpgd valence space.Comment: 4 pages, 2 figure

    Polymer depletion interaction between two parallel repulsive walls

    Get PDF
    The depletion interaction between two parallel repulsive walls confining a dilute solution of long and flexible polymer chains is studied by field-theoretic methods. Special attention is paid to self-avoidance between chain monomers relevant for polymers in a good solvent. Our direct approach avoids the mapping of the actual polymer chains on effective hard or soft spheres. We compare our results with recent Monte Carlo simulations [A. Milchev and K. Binder, Eur. Phys. J. B 3, 477 (1998)] and with experimental results for the depletion interaction between a spherical colloidal particle and a planar wall in a dilute solution of nonionic polymers [D. Rudhardt, C. Bechinger, and P. Leiderer, Phys. Rev. Lett. 81, 1330 (1998)].Comment: 17 pages, 3 figures. Final version as publishe
    corecore