18 research outputs found
Whole-scalp EEG mapping of somatosensory evoked potentials in macaque monkeys
High-density scalp EEG recordings are widely used to study whole-brain neuronal networks in humans non-invasively. Here, we validate EEG mapping of somatosensory evoked potentials (SSEPs) in macaque monkeys (Macaca fascicularis) for the long-term investigation of large-scale neuronal networks and their reorganisation after lesions requiring a craniotomy. SSEPs were acquired from 33 scalp electrodes in five adult anaesthetized animals after electrical median or tibial nerve stimulation. SSEP scalp potential maps were identified by cluster analysis and identified in individual recordings. A distributed, linear inverse solution was used to estimate the intracortical sources of the scalp potentials. SSEPs were characterised by a sequence of components with unique scalp topographies. Source analysis confirmed that median nerve SSEP component maps were in accordance with the somatotopic organisation of the sensorimotor cortex. Most importantly, SSEP recordings were stable both intra- and interindividually. We aim to apply this method to the study of recovery and reorganisation of large-scale neuronal networks following a focal cortical lesion requiring a craniotomy. As a prerequisite, the present study demonstrated that a 300-mm2 unilateral craniotomy over the sensorimotor cortex necessary to induce a cortical lesion, followed by bone flap repositioning, suture and gap plugging with calcium phosphate cement, did not induce major distortions of the SSEPs. In conclusion, SSEPs can be successfully and reproducibly recorded from high-density EEG caps in macaque monkeys before and after a craniotomy, opening new possibilities for the long-term follow-up of the cortical reorganisation of large-scale networks in macaque monkeys after a cortical lesion
Ictiofauna de la pesquerĂa ribereña en BahĂa de Navidad, Jalisco, MĂ©xico, asociada al evento El Niño 1997-1998
The ichthyofauna fished in BahĂa de Navidad, Jalisco, Mexico in the Central Pacific was surveyed during 1998. Six thousand nine hundred and fourty-four organisms of 130 species were caught which weighted 3 231 kg. Nearly 30 % of the species belonged to Carangidae, Haemulidae and Sciaenidae. The most important species in number and biomass were Microlepidotus brevipinnins, Caranx caninus and C. caballus. Species number abundance and biomass fluctuated during the year. The largest number of species was caught in June (61), the minimum in March (33). January had the maximum abundance (1 397 organisms), while the minimum was obtained during August (251). The maximum biomass values were from January (556.5 kg), and the lowest from August (114.7 kg). Eighteen species accumulated 87 % of the total abundance, while 20 species represented 86.3 % of the biomass. There were large in differences species number, abundance and biomass nets of different mesh size
Ictiofauna de la pesquerĂa ribereña en BahĂa de Navidad, Jalisco, MĂ©xico, asociada al evento El Niño 1997-1998
The ichthyofauna fished in BahĂa de Navidad, Jalisco, Mexico in the Central Pacific was surveyed during 1998. Six thousand nine hundred and fourty-four organisms of 130 species were caught which weighted 3 231 kg. Nearly 30 % of the species belonged to Carangidae, Haemulidae and Sciaenidae. The most important species in number and biomass were Microlepidotus brevipinnins, Caranx caninus and C. caballus. Species number abundance and biomass fluctuated during the year. The largest number of species was caught in June (61), the minimum in March (33). January had the maximum abundance (1 397 organisms), while the minimum was obtained during August (251). The maximum biomass values were from January (556.5 kg), and the lowest from August (114.7 kg). Eighteen species accumulated 87 % of the total abundance, while 20 species represented 86.3 % of the biomass. There were large in differences species number, abundance and biomass nets of different mesh size
The problems of organizational maintenance and the League of United Latin American Citizens
Chiral Hydrogen Bond Environment Providing Unidirectional Rotation in Photoactive Molecular Motors
Hemodynamic Features of Symptomatic Vertebrobasilar Disease
Background and purposeAtherosclerotic vertebrobasilar disease is an important cause of posterior circulation stroke. To examine the role of hemodynamic compromise, a prospective multicenter study, Vertebrobasilar Flow Evaluation and Risk of Transient Ischemic Attack and Stroke (VERiTAS), was conducted. Here, we report clinical features and vessel flow measurements from the study cohort.MethodsPatients with recent vertebrobasilar transient ischemic attack or stroke and ≥50% atherosclerotic stenosis or occlusion in vertebral or basilar arteries (BA) were enrolled. Large-vessel flow in the vertebrobasilar territory was assessed using quantitative MRA.ResultsThe cohort (n=72; 44% women) had a mean age of 65.6 years; 72% presented with ischemic stroke. Hypertension (93%) and hyperlipidemia (81%) were the most prevalent vascular risk factors. BA flows correlated negatively with percentage stenosis in the affected vessel and positively to the minimal diameter at the stenosis site (P<0.01). A relative threshold effect was evident, with flows dropping most significantly with ≥80% stenosis/occlusion (P<0.05). Tandem disease involving the BA and either/both vertebral arteries had the greatest negative impact on immediate downstream flow in the BA (43 mL/min versus 71 mL/min; P=0.01). Distal flow status assessment, based on an algorithm incorporating collateral flow by examining distal vessels (BA and posterior cerebral arteries), correlated neither with multifocality of disease nor with severity of the maximal stenosis.ConclusionsFlow in stenotic posterior circulation vessels correlates with residual diameter and drops significantly with tandem disease. However, distal flow status, incorporating collateral capacity, is not well predicted by the severity or location of the disease