108 research outputs found
The twistor spinors of generic 2- and 3-distributions
Generic distributions on 5- and 6-manifolds give rise to conformal structures
that were discovered by P. Nurowski resp. R. Bryant. We describe both as
Fefferman-type constructions and show that for orientable distributions one
obtains conformal spin structures. The resulting conformal spin geometries are
then characterized by their conformal holonomy and equivalently by the
existence of a twistor spinor which satisfies a genericity condition. Moreover,
we show that given such a twistor spinor we can decompose a conformal Killing
field of the structure. We obtain explicit formulas relating conformal Killing
fields, almost Einstein structures and twistor spinors.Comment: 26 page
Co-occurrence of the bla(VIM-1) and bla(SHV-12) genes on an IncHI2 plasmid of an Escherichia coli isolate recovered from German livestock
The dissemination of carbapenemase-producing Enterobacterales (CPE) is an important public health issue. The number of human CPE isolates has been steadily increasing during recent years, worldwide. Despite the fact that carbapenems are not licensed for use in veterinary medicine, increasing numbers of CPE from the veterinary sector have been reported. The transmission of CPE between pets/livestock and exposed humans as well as via food has been demonstrated. In this study, a detailed characterization of a carbapenem-resistant porcine Escherichia coli co-harbouring blaVIM-1, blaSHV-12 and blaACC-1 genes, along with other resistance genes, is provided
Seasonal Effects of Extreme Weather Events on Potential Extracellular Enzyme Activities in a Temperate Grassland Soil
Magnitude and timing of precipitation events within the growing season might be decisive for alterations in potential extracellular enzyme activity (PEEA), with consequences for nutrient cycle, and carbon storage in grassland ecosystems. Pattern of PEEA catalyzing major steps of the carbon cycle (β-glucosidase (β-gls), cellobiohydrolase (cel), glucuronidase (glr), and xylosidase (xyl), soil respiration rates and extractable organic carbon were analyzed in response to increased intra-annual precipitation variability in a European, mesic temperate grassland. The field experiment was carried out in three subsequent years by simulating recurrent drought events combined with heavy rainfall either early or late in the growing season (spring or summer) by rainout shelters and irrigation systems. Our data indicated comparable effects of the drought settings independent from the timing of the drought. Both for the simulated spring- and summer drought a decrease of enzymatic activities was observed compared to the control plots, with ß-gls activity after the summer drought being the only exception. However, response pattern toward rewetting differed depending on the seasonal timing of the drought being introduced. After spring drought, a fast recovery to control level was observed for PEEA of ß-gls and xyl, whereas cel and glr activity remained constantly lower. Rewetting after summer drought induced an increase of all enzymatic activities to values even higher compared to the controls. Overall, our data indicate a high resilience of PEEA toward drought and rewetting events in grassland soils, which is modulated by the seasonal timing of the extreme weather events
What limits supercurrents in high temperature superconductors? A microscopic model of cuprate grain boundaries
The interface properties of high-temperature cuprate superconductors have
been of interest for many years, and play an essential role in Josephson
junctions, superconducting cables, and microwave electronics. In particular,
the maximum critical current achievable in high-Tc wires and tapes is well
known to be limited by the presence of grain boundaries, regions of mismatch
between crystallites with misoriented crystalline axes. In studies of single,
artificially fabricated grain boundaries the striking observation has been made
that the critical current Jc of a grain boundary junction depends exponentially
on the misorientation angle. Until now microscopic understanding of this
apparently universal behavior has been lacking. We present here the results of
a microscopic evaluation based on a construction of fully 3D YBCO grain
boundaries by molecular dynamics. With these structures, we calculate an
effective tight-binding Hamiltonian for the d-wave superconductor with a grain
boundary. The critical current is then shown to follow an exponential
suppression with grain boundary angle. We identify the buildup of charge
inhomogeneities as the dominant mechanism for the suppression of the
supercurrent.Comment: 28 pages, 12 figure
Flux flow of Abrikosov-Josephson vortices along grain boundaries in high-temperature superconductors
We show that low-angle grain boundaries (GB) in high-temperature
superconductors exhibit intermediate Abrikosov vortices with Josephson cores,
whose length along GB is smaller that the London penetration depth, but
larger than the coherence length. We found an exact solution for a periodic
vortex structure moving along GB in a magnetic field and calculated the
flux flow resistivity , and the nonlinear voltage-current
characteristics. The predicted dependence describes well our
experimental data on unirradiated and irradiated
bicrystals, from which the core size , and the intrinsic depairing
density on nanoscales of few GB dislocations were measured for the
first time. The observed temperature dependence of
indicates a significant order parameter suppression in current channels between
GB dislocation cores.Comment: 5 pages 5 figures. Phys. Rev. Lett. (accepted
Multiplex PCR for detection of plasmid-mediated colistin resistance determinants, mcr-1, mcr-2, mcr-3, mcr-4 and mcr-5 for surveillance purposes
Background and aim: Plasmid-mediated colistin resistance mechanisms have been identified worldwide in the past years. A multiplex polymerase chain reaction (PCR) protocol for detection of all currently known transferable colistin resistance genes (mcr-1 to mcr-5, and variants) in Enterobacteriaceae was developed for surveillance or research purposes. Methods: We designed four new primer pairs to amplify mcr-1, mcr-2, mcr-3 and mcr-4 gene products and used the originally described primers for mcr-5 to obtain a stepwise separation of ca 200 bp between ampli-cons. The primer pairs and amplification conditions allow for single or multiple detection of all currently described mcr genes and their variants present in Enterobacteriaceae. The protocol was validated testing 49 European Escherichia coli and Salmonella isolates of animal origin. Results: Multiplex PCR results in bovine and porcine isolates from Spain, Germany, France and Italy showed full concordance with whole genome sequence data. The method was able to detect mcr-1, mcr-3 and mcr-4 as singletons or in different combinations as they were present in the test isolates. One new mcr-4 variant, mcr-4.3, was also identified. Conclusions: This method allows rapid identification of mcr-positive bacteria and overcomes the challenges of phenotypic detection of colistin resistance. The multiplex PCR should be particularly interesting in settings or laboratories with limited resources for performing genetic analysis as it provides information on the mechanism of colistin resistance without requiring genome sequencing. © 2018, European Centre for Disease Prevention and Control (ECDC). All rights reserved
Degenerate ground state in a mesoscopic YBaCuO grain boundary Josephson junction
We have measured the current-phase relationship (CPR) of symmetric 45 degree
YBaCuO grain boundary Josephson junctions. Substantial deviations of the CPR
from conventional tunnel-junction behavior have been observed: (i) The critical
current exhibits, as a function of temperature T, a local minimum at a
temperature T*. (ii) At T approximately equal to T*, the first harmonic of the
CPR changes sign. (iii) For T<T*, the second harmonic of the CPR is comparable
to the first harmonic, and (iv) the ground state of the junction becomes
degenerate. The results are in good agreement with a microscopic model of
Josephson junctions between d-wave superconductors.Comment: 4 pages, 5 figures, a reference adde
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