537 research outputs found
Les usages sociaux et touristiques des espaces littoraux. Eléments de comparaison entre la France et la Chine
International audienc
Introduction » au dossier « Méthodologie complexe et plurielle dans la recherche doctorale en sciences sociales
L’hybridation méthodologique au coeur d’une journée d’étude à destination des doctorant.e.s de l’UMR ES
The role of antibiotics in the treatment of chronic prostatitis: A consensus statement
Practical guidelines for the diagnosis and treatment of chronic prostatitis are presented. Chronic prostatitis is classified as chronic bacterial prostatitis (culture-positive) and chronic inflammatory prostatitis (culture-negative). If chronic bacterial prostatitis is suspected, based on relevant symptoms or recurrent UTIs, underlying urological conditions should be excluded by the following tests: rectal examination, midstream urine culture and residual urine. The diagnosis should be confirmed by the Meares and Stamey technique. Antibiotic therapy is recommended for acute exacerbations of chronic prostatitis, chronic bacterial prostatitis and chronic inflammatory prostatitis, if there is clinical, bacteriological or supporting immunological evidence of prostate infection. Unless a patient presents with fever, antibiotic treatment should not be initiated immediately except in cases of acute prostatitis or acute episodes in a patient with chronic bacterial prostatitis. The work-up, with the appropriate investigations should be done first, within a reasonable time period which, preferably, should not be longer than 1 week. During this period, nonspecific treatment, such as appropriate analgesia to relieve symptoms, should be given. The minimum duration of antibiotic treatment should be 2-4 weeks. If there is no improvement in symptoms, treatment should be stopped and reconsidered. However, if there is improvement, it should be continued for at least a further 2-4 weeks to achieve clinical cure and, hopefully, eradication of the causative pathogen. Antibiotic treatment should not be given for 6-8 weeks without an appraisal of its effectiveness. Currently used antibiotics are reviewed. Of these, the fluoroquinolones ofloxacin and ciprofloxacin are recommended because of their favourable antibacterial spectrum and pharmacokinetic profile. A number of clinical trials are recommended and a standard study design is proposed to help resolve some outstanding issues
Circulating microparticles from pulmonary hypertensive rats are vectors of oxidative stress
Date du colloque : 04/2010National audienc
The Role of Pressure in GMC Formation II: The H_2 - Pressure Relation
We show that the ratio of molecular to atomic gas in galaxies is determined
by hydrostatic pressure and that the relation between the two is nearly linear.
The pressure relation is shown to be good over three orders of magnitude for 14
galaxies including dwarfs, HI-rich, and H_2-rich galaxies as well as the Milky
Way. The sample spans a factor of five in mean metallicity. The rms scatter of
individual points of the relation is only about a factor of two for all the
galaxies, though some show much more scatter than others. Using these results,
we propose a modified star formation prescription based on pressure determining
the degree to which the ISM is molecular. The formulation is different in high
and low pressure regimes defined by whether the gas is primarily atomic or
primarily molecular. This formulation can be implemented in simulations and
provides a more appropriate treatment of the outer regions of spiral galaxies
and molecule-poor systems such as dwarf irregulars and damped Lyman-alpha
systems.Comment: 14 pages, 7 figures, Accepted to the Astrophysical Journa
Survey for Emission-Line Galaxies: Universidad Complutense de Madrid List 3
A new low-dispersion objective-prism search for low-redshift (z<0.045)
emission-line galaxies (ELG) has been carried out by the Universidad
Complutense de Madrid with the Schmidt Telescope at the Calar-Alto Observatory.
This is a continuation of the UCM Survey, which was performed by visual
selection of candidates in photographic plates via the presence of the
Halpha+[NII]6584 blend in emission. In this new list we have applied an
automatic procedure, fully developed by us, for selecting and analyzing the ELG
candidates on the digitized images obtained with the MAMA machine. The analyzed
region of the sky covers 189 square degrees in nine fields near R.A.=14h & 17h,
Dec=25 deg. The final sample contains 113 candidates. Special effort has been
made to obtain a large amount of information directly from our uncalibrated
plates by using several external calibrations. The parameters obtained for the
ELG candidates allow for the study of the statistical properties for the
sample.Comment: 13 pages, 18 PostScript figures, 6 JPEG figures, Table 2 corrected.
Accepted for publication in Astrophysical Journal Supplements, also available
at http://www.ucm.es/info/Astrof/opera/LIST3_ApJS99
Rematérialiser les études touristiques
Ce chapitre analyse les enjeux de l’approche matérialiste du tourisme en géographie et, plus largement, dans le champ des sciences sociales. Ces enjeux sont d\u27abord discutés à la lumière des évolutions théoriques que connaît la recherche touristique depuis une vingtaine d’années. Alors que la perspective économique a dominé ce champ de recherche jusqu’aux années 1980, les études touristiques sont particulièrement marquées par l’influence du tournant culturel depuis le début des années 1990. Si ce glissement théorique a permis une meilleure compréhension du tourisme, en particulier à travers l’étude des pratiques et des imaginaires touristiques, cette évolution a aussi contribué à éloigner la recherche touristique de l’analyse des inégalités sociales et des rapports de domination. Partant de ce constat, le texte propose une réflexion théorique permettant de ramener l’étude géographique du tourisme dans le champ des approches matérialistes. Une telle démarche s’appuie pour cela sur des recherches empiriques menées au Mexique autour de conflits locaux pour l’appropriation d’espaces touristiques, mais aussi sur un certain nombre de questionnements plus théoriques sur la dimension spatiale du tourisme. L’approche développée s’appuie notamment sur l’héritage théorique du philosophe marxiste Henri Lefebvre dont les travaux alimentent une « économie politique de l’espace ». Le retour au matérialisme historique est ainsi envisagé comme un moyen d’alimenter la lecture critique du tourisme tout en évitant les écueils des approches structuralistes et marxistes développées dans les années 1970. De cette manière, il s’agit également de montrer l’apport des études touristiques à la compréhension plus globale des sociétés capitalistes contemporaines
Motivic Serre invariants, ramification, and the analytic Milnor fiber
We show how formal and rigid geometry can be used in the theory of complex
singularities, and in particular in the study of the Milnor fibration and the
motivic zeta function. We introduce the so-called analytic Milnor fiber
associated to the germ of a morphism f from a smooth complex algebraic variety
X to the affine line. This analytic Milnor fiber is a smooth rigid variety over
the field of Laurent series C((t)). Its etale cohomology coincides with the
singular cohomology of the classical topological Milnor fiber of f; the
monodromy transformation is given by the Galois action. Moreover, the points on
the analytic Milnor fiber are closely related to the motivic zeta function of
f, and the arc space of X.
We show how the motivic zeta function can be recovered as some kind of Weil
zeta function of the formal completion of X along the special fiber of f, and
we establish a corresponding Grothendieck trace formula, which relates, in
particular, the rational points on the analytic Milnor fiber over finite
extensions of C((t)), to the Galois action on its etale cohomology.
The general observation is that the arithmetic properties of the analytic
Milnor fiber reflect the structure of the singularity of the germ f.Comment: Some minor errors corrected. The original publication is available at
http://www.springerlink.co
ORAI Channels as Potential Therapeutic Targets in Pulmonary Hypertension
Pulmonary hypertension is a complex and fatal disease that lacks treatments. Its pathophysiology involves pulmonary artery hyperreactivity, endothelial dysfunction, wall remodelling, inflammation, and thrombosis, which could all depend on ORAI Ca2+ channels. We review the knowledge about ORAI channels in pulmonary artery and discuss the interest to target them in the treatment of pulmonary hypertension
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