Marxist history and schooling: Beyond economism

Marxist history emphasises the linkage between economic production, social institutions and everyday life. Critics of Marxism claim that its analysis of schooling is simplistic, functional and deterministic The first part of this paper examines whether Marxist historical practice was in fact deterministic. It offers a non-reductionist and non-economistic reading of Marx's historical methodology. The second section moves on to consider some of the ways in which post-structuralist theorising can 'loosen-up' and revitalise mechanistic Marxist interpretations of the history of schooling

A critical pedagogy of vocational education and training in schools and communities struggling with shifts in the global economy

This article argues that if students in disadvantaged schools and communities are going to receive a fair go then we must begin to interrupt existing conceptions of vocational education and training, in particular the ways in which they perpetuate established social hierarchies based on class, race and gender. Listening to the experiences of over 125 teachers, students and parents from four disadvantaged schools in the outer metropolitan suburbs of Perth, Western Australia (Smyth & Down, 2005) it soon becomes apparent that the new realities of the global economy fuelled by the increasingly successful educational policies and practices of the New Right are (re)shaping schools to better fit the narrow sectional interests of the economy. As politicians, business and corporate interests continue their sustained attacks on public schooling we are witnessing the emergence of what Apple (2001) describes as "conservative modernization" whereby educational commonsense is redefined around a set of neo-liberal and neo-conservative values: ... we are told to "free" our school by placing them into the competitive market, restore "our" traditional common culture and stress discipline and character, return God to our classrooms as a guide to all our conduct inside and outside the school, and tighten central control through more rigorous and tough-minded standards and tests. This is all supposed to be done at the same time. It is all supposed to guarantee an education that benefits everyone. Well, maybe not (p.5)

Relational pedagogy for student engagement and success at university

The Australian Government's policy to transform higher education by 2020 includes plans to significantly raise the levels of undergraduate enrolment by people of low socio-economic status. In light of this policy direction, this article examines how a group of undergraduate students of low socio-economic status work to maintain their desire for learning and to remain included in the university system despite experiencing cultural processes of exclusion. As the students reflect on the cultural and pedagogical conditions that promote, support and enhance their participation and engagement in higher education, a picture emerges of the importance of students' relationships with academics. Whilst positive relationships help students to remain engaged, negative experiences work against continuing participation and engagement. Given the desire of the Australian government to increase participation in higher education by students from under-represented groups, this research identifies some challenges and possibilities for both universities and academics

Craft as a Liberal Education: A Response

It is important to correct some of the impressions that may have been created by Mr. Allen in his last issue of Studies in Design Education and Craft 9.1. Specifically I want to examine the Peters' analysis of education and the Hirst account of liberal education with reference to the place of craft education in the curriculum. I will maintain that an acceptance of the Peters-Hirst theses is perfectly consistent with an emphasis on craft education

Whole-thorax irradiation induces hypoxic respiratory failure, pleural effusions and cardiac remodeling

To study the mechanisms of death following a single lethal dose of thoracic radiation, WAG/RijCmcr (Wistar) rats were treated with 15 Gy to the whole thorax and followed until they were morbid or sacrificed for invasive assays at 6 weeks. Lung function was assessed by breathing rate and arterial oxygen saturation. Lung structure was evaluated histologically. Cardiac structure and function were examined by echocardiography. The frequency and characteristics of pleural effusions were determined. Morbidity from 15 Gy radiation occurred in all rats 5 to 8 weeks after exposure, coincident with histological pneumonitis. Increases in breathing frequencies peaked at 6 weeks, when profound arterial hypoxia was also recorded. Echocardiography analysis at 6 weeks showed pulmonary hypertension and severe right ventricular enlargement with impaired left ventricular function and cardiac output. Histologic sections of the heart revealed only rare foci of lymphocytic infiltration. Total lung weight more than doubled. Pleural effusions were present in the majority of the irradiated rats and contained elevated protein, but low lactate dehydrogenase, when compared with serum from the same animal. Pleural effusions had a higher percentage of macrophages and large monocytes than neutrophils and contained mast cells that are rarely present in other pathological states. Lethal irradiation to rat lungs leads to hypoxia with infiltration of immune cells, edema and pleural effusion. These changes may contribute to pulmonary vascular and parenchymal injury that result in secondary changes in heart structure and function. We report that conditions resembling congestive heart failure contribute to death during radiation pneumonitis, which indicates new targets for therapy

稲垣足穂『少年愛の美学』の読書論的研究 --念者としての語り--

千葉大学大学院人文社会科学研究科研究プロジェクト報告書第144集 『パフォーマンスの民族誌的研究』橋本裕之

Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications.

Analysis of DNA methylation patterns relies increasingly on sequencing-based profiling methods. The four most frequently used sequencing-based technologies are the bisulfite-based methods MethylC-seq and reduced representation bisulfite sequencing (RRBS), and the enrichment-based techniques methylated DNA immunoprecipitation sequencing (MeDIP-seq) and methylated DNA binding domain sequencing (MBD-seq). We applied all four methods to biological replicates of human embryonic stem cells to assess their genome-wide CpG coverage, resolution, cost, concordance and the influence of CpG density and genomic context. The methylation levels assessed by the two bisulfite methods were concordant (their difference did not exceed a given threshold) for 82% for CpGs and 99% of the non-CpG cytosines. Using binary methylation calls, the two enrichment methods were 99% concordant and regions assessed by all four methods were 97% concordant. We combined MeDIP-seq with methylation-sensitive restriction enzyme (MRE-seq) sequencing for comprehensive methylome coverage at lower cost. This, along with RNA-seq and ChIP-seq of the ES cells enabled us to detect regions with allele-specific epigenetic states, identifying most known imprinted regions and new loci with monoallelic epigenetic marks and monoallelic expression

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus

BACKGROUND: Diabetic nephropathy is a serious complication of diabetes mellitus and is associated with considerable morbidity and high mortality. There is increasing evidence to suggest that dysregulation of the epigenome is involved in diabetic nephropathy. We assessed whether epigenetic modification of DNA methylation is associated with diabetic nephropathy in a case-control study of 192 Irish patients with type 1 diabetes mellitus (T1D). Cases had T1D and nephropathy whereas controls had T1D but no evidence of renal disease. METHODS: We performed DNA methylation profiling in bisulphite converted DNA from cases and controls using the recently developed Illumina Infinium(R) HumanMethylation27 BeadChip, that enables the direct investigation of 27,578 individual cytosines at CpG loci throughout the genome, which are focused on the promoter regions of 14,495 genes. RESULTS: Singular Value Decomposition (SVD) analysis indicated that significant components of DNA methylation variation correlated with patient age, time to onset of diabetic nephropathy, and sex. Adjusting for confounding factors using multivariate Cox-regression analyses, and with a false discovery rate (FDR) of 0.05, we observed 19 CpG sites that demonstrated correlations with time to development of diabetic nephropathy. Of note, this included one CpG site located 18 bp upstream of the transcription start site of UNC13B, a gene in which the first intronic SNP rs13293564 has recently been reported to be associated with diabetic nephropathy. CONCLUSION: This high throughput platform was able to successfully interrogate the methylation state of individual cytosines and identified 19 prospective CpG sites associated with risk of diabetic nephropathy. These differences in DNA methylation are worthy of further follow-up in replication studies using larger cohorts of diabetic patients with and without nephropathy

Big Picture Education Australia: Experiences of students, parents/carers & teachers

Too many young Australians, especially those from disadvantaged circumstances, are not benefiting from the rewards of education and training. For others, there is a growing sense of frustration and alienation about the kind of education they receive, and from their point of view school is boring, irrelevant and disconnected from the world they know. For many, there is a lack of personal connectedness and meaning as their own needs, desires, aspirations and interests are denied in large high school settings where the focus is on subjects, timetables, discipline, didactic teaching, examinations, and classroom-based learning. These historically persistent and protracted problems have preoccupied policymakers, researchers and school reformers for the past sixty years or more. Whilst hardly new, the issue of student (dis)engagement is an increasingly urgent public policy matter not only in terms of economics - cost, productivity, global competitiveness, innovation and human capital, but also social cohesion, mental health and wellbeing, social justice, and democracy itself. At a time when young people face an increasingly volatile and uncertain future due to the impact of globalisation, deindustrialisation, technology, and job insecurity, schools are under pressure to resolve some complex social, economic and political problems not always of their own making. Ironically, schools are often perceived to be a part of the problem and also the solution. Against this broader backdrop, this report attempts to identify, map and describe the experiences of students, their parents/carers and teachers attending schools in a range of sites across Australia adopting an interest-based approach to learning. The intent is to illuminate the experiences of these participants and, from their vantage point, better understand how this approach might address questions of student engagement, school reform, school leadership, curriculum, organisation, assessment and school-community relationships

‘Sons of athelings given to the earth’: Infant Mortality within Anglo-Saxon Mortuary Geography

FOR 20 OR MORE YEARS early Anglo-Saxon archaeologists have believed children are underrepresented in the cemetery evidence. They conclude that excavation misses small bones, that previous attitudes to reporting overlook the very young, or that infants and children were buried elsewhere. This is all well and good, but we must be careful of oversimplifying compound social and cultural responses to childhood and infant mortality. Previous approaches have offered methodological quandaries in the face of this under-representation. However, proportionally more infants were placed in large cemeteries and sometimes in specific zones. This trend is statistically significant and is therefore unlikely to result entirely from preservation or excavation problems. Early medieval cemeteries were part of regional mortuary geographies and provided places to stage events that promoted social cohesion across kinship systems extending over tribal territories. This paper argues that patterns in early Anglo-Saxon infant burial were the result of female mobility. Many women probably travelled locally to marry in a union which reinforced existing social networks. For an expectant mother, however, the safest place to give birth was with experience women in her maternal home. Infant identities were affected by personal and legal association with their mother’s parental kindred, so when an infant died in childbirth or months and years later, it was their mother’s identity which dictated burial location. As a result, cemeteries central to tribal identities became places to bury the sons and daughters of a regional tribal aristocracy