A study of the thermoregulatory characteristics of a liquid-cooled garment with automatic temperature control based on sweat rate: Experimental investigation and biothermal man-model development

Experimental results for three subjects walking on a treadmill at exercise rates of up to 590 watts showed that thermal comfort could be maintained in a liquid cooled garment by using an automatic temperature controller based on sweat rate. The addition of head- and neck-cooling to an Apollo type liquid cooled garment increased its effectiveness and resulted in greater subjective comfort. The biothermal model of man developed in the second portion of the study utilized heat rates and exchange coefficients based on the experimental data, and included the cooling provisions of a liquid-cooled garment with automatic temperature control based on sweat rate. Simulation results were good approximations of the experimental results

Evaluation of non-intrusive flow measurement techniques for a re-entry flight experiment

This study evaluates various non-intrusive techniques for the measurement of the flow field on the windward side of the Space Shuttle orbiter or a similar reentry vehicle. Included are linear (Rayleigh, Raman, Mie, Laser Doppler Velocimetry, Resonant Doppler Velocimetry) and nonlinear (Coherent Anti-Stokes Raman, Laser-Induced Fluorescence) light scattering, electron-beam fluorescence, thermal emission, and mass spectroscopy. Flow-field properties were taken from a nonequilibrium flow model by Shinn, Moss, and Simmonds at the NASA Langley Research Center. Conclusions are, when possible, based on quantitative scaling of known laboratory results to the conditions projected. Detailed discussion with researchers in the field contributed further to these conclusions and provided valuable insights regarding the experimental feasibility of each of the techniques

Non-intrusive flow measurements on a reentry vehicle

This study evaluates the utility of various non-intrusive techniques for the measurement of the flow field on the windward side of the Space Shuttle or a similar re-entry vehicle. Included are linear (Rayleigh, Raman, Mie, Laser Doppler Velocimetry, Resonant Doppler Velocimetry) and nonlinear (Coherent Anti-Stokes Raman, Laser Induced Fluorescence) light scattering, electron beam fluorescence, thermal emission and mass spectroscopy. Flow field properties are taken from a nonequilibrium flow model by Shinn, Moss and Simmonds at NASA Langley. Conclusions are, when possible, based on quantitative scaling of known laboratory results to the conditions projected. Detailed discussion with researchers in the field contributed further to these conclusions and provided valuable insights regarding the experimental feasibility of each of the techniques

DichroMatch: a website for similarity searching of circular dichroism spectra

Circular dichroism (CD) spectroscopy is a widely used method for examining the structure, folding and conformational changes of proteins. A new online CD analysis server (DichroMatch) has been developed for identifying proteins with similar spectral characteristics by detecting possible structurally and functionally related proteins and homologues. DichroMatch includes six different methods for determining the spectral nearest neighbours to a query protein spectrum and provides metrics of how similar these spectra are and, if corresponding crystal structures are available for the closest matched proteins, information on their secondary structures and fold classifications. By default, DichroMatch uses all the entries in the Protein Circular Dichroism Data Bank (PCDDB) for its comparison set, providing the broadest range of publicly available protein spectra to match with the unknown protein. Alternatively, users can download or create their own specialized data sets, thereby enabling comparisons between the structures of related proteins such as wild-type versus mutants or homologues or a series of spectra of the same protein under different conditions. The DichroMatch server is freely available at http://dichromatch.cryst.bbk.ac.uk

Exploring the relationship between effective and reflective practice in applied sport psychology

This study offers an investigation into the concept of effective practice in applied sport psychology (ASP) with emphasis being placed upon the role that reflective practice may have in helping practitioners to develop the effectiveness of their service delivery. Focus groups (n = 2), consisting of accredited and trainee sport psychologists, were conducted to generate a working definition of effective practice, and discuss the concept of effectiveness development through engagement in reflective practices. The resulting definition encapsulated a multidimensional process involving reflection-on-practice. Initial support for the definition was gained through consensus validation involving accredited sport psychologists (n = 34) who agreed with the notion that although effectiveness is context specific it is related to activities designed to meet client needs. Reflective practice emerged as a vital component in the development of effectiveness, with participants highlighting that reflection is intrinsically linked to service delivery, and a key tool for experiential learning.</jats:p

Unsolicited written narratives as a methodological genre in terminal illness: challenges and limitations

Stories about illness have proven invaluable in helping health professionals understand illness experiences. Such narratives have traditionally been solicited by researchers through interviews and the collection of personal writings, including diaries. These approaches are, however, researcher driven; the impetus for the creation of the story comes from the researcher and not the narrator. In recent years there has been exponential growth in illness narratives created by individuals, of their own volition, and made available for others to read in print or as Internet accounts. We sought to determine whether it was possible to identify such material for use as research data to explore the subject of living with the terminal illness amyotrophic lateral sclerosis/motor neuron disease—the contention being that these accounts are narrator driven and therefore focus on issues of greatest importance to the affected person. We encountered and sought to overcome a number of methodological and ethical challenges, which is our focus here

ValiDichro: a website for validating and quality control of protein circular dichroism spectra

Circular dichroism (CD) spectroscopy is widely used in structural biology as a technique for examining the structure, folding and conformational changes of proteins. A new server, ValiDichro, has been developed for checking the quality and validity of CD spectral data and metadata, both as an aid to data collection and processing and as a validation procedure for spectra to be included in publications. ValiDichro currently includes 25 tests for data completeness, consistency and quality. For each test that is done, not only is a validation report produced, but the user is also provided with suggestions for correcting or improving the data. The ValiDichro server is freely available at http://valispec.cryst.bbk.ac.uk/circularDichroism/ValiDichro/upload.html

West Antarctic ice sheet and CO2 greenhouse effect: a threat of disaster

DIB's contribution to this work is from the DOMINOS project, a component of the International Thwaites Glacier Collaboration (ITGC). Support for DIB was provided by the Natural Environment Research Council (NERC: Grant NE/S006605/1). ITGC Contribution No. ITGC:025.Over 40 years ago, the glaciologist John Mercer warned that parts of the West Antarctic Ice Sheet were at risk of collapse due to the CO2 greenhouse effect. Mercer recognised the unique vulnerability of ice sheets resting on beds far below sea level (marine-based ice sheets), where an initial warming signal can initiate irreversible retreat. In this paper, we review recent work on evidence for ice sheet collapse in warmer periods of the recent geological past, the current behaviour of the ice sheet, and computer models used to predict future ice-sheet response to global warming. Much of this work points in the same direction: warming climates can indeed trigger collapse of marine-based portions of the West Antarctic Ice Sheet, and retreat in response to recent warming has brought parts of the ice sheet to the threshold of instability. Further retreat appears to be inevitable, but the rate of collapse depends critically on future emissions.Publisher PDFPeer reviewe

Testing the existence of optical linear polarization in young brown dwarfs

Linear polarization can be used as a probe of the existence of atmospheric condensates in ultracool dwarfs. Models predict that the observed linear polarization increases withthe degree of oblateness, which is inversely proportional to the surface gravity. We aimed to test the existence of optical linear polarization in a sample of bright young brown dwarfs, with spectral types between M6 and L2, observable from the Calar Alto Observatory, and cataloged previously as low gravity objects using spectroscopy. Linear polarimetric images were collected in I and R-band using CAFOS at the 2.2 m telescope in Calar Alto Observatory (Spain). The flux ratio method was employed to determine the linear polarization degrees. With a confidence of 3$\sigma$, our data indicate that all targets have a linear polarimetry degree in average below 0.69% in the I-band, and below 1.0% in the R-band, at the time they were observed. We detected significant (i.e. P/$\sigma$ $\le$ 3) linear polarization for the young M6 dwarf 2MASS J04221413+1530525 in the R-band, with a degree of $\mathrm{p^{*}}$ = 0.81 $\pm$ 0.17 %.Comment: Accepted for publication in MNRA

Localized pulsed nanosecond discharges in a counterflow nonpremixed flame environment

A flame is a very unusual environment for the development of a gas discharge, since it presents strong gradients in temperature, composition, and pre-ionization. In this paper we examine how such an environment impacts the development of the plasma when using repetitive pulsed nanosecond discharges, one of the main strategies used in the field of plasma assisted combustion. Experiments were performed in a counterflow nonpremixed burner with parallel electrodes at the nozzle exits and nanosecond-resolved photography of the plasma emission is presented. It was shown that the discharge development in stratified media may take place in the form of a dielectric barrier discharge with a localized energy deposition. In the experiments presented the discharge energy was coupled to the flame front because of the high rate of chemi-ionization and the gas density decrease in the flame