Design and Development of Sur-Face: An interactive mobile app for educating patients regarding corrective surgery of facial deformities

Corrective surgery of face, also known as orthognathic surgery, is a complex procedure performed to correct the underlying facial deformities. In case of elective surgeries like these, patients need to make voluntary decisions whether or not undergoing the surgery. Hence, it is very important for them to under-stand the intricacy of the techniques and potential side effects of the surgery before they sign the consent form. Conventional methods of patient education us-ing leaflet-based instructions were found to be ineffective in providing them the required information. Sur-Face, named after surgery of face is a healthcare app exploring a new dimension in patient education with the help of interactive 3D visualizations and serious gaming elements on a mobile platform. It demonstrates the surgical process and it’s after effects using high quality 3D animations. The aim of this study is to evaluate the efficacy of Sur-Face by comparing two methods of delivery of instructions: a mobile app with interactive 3D animations and an audio file containing only verbal instructions. To evaluate these methods, participant’s ability to understand and retain the instructions was analyzed using a questionnaire. The null hypothesis was that there would be no difference between the two methods of instructions. On analysis, participants of the ‘app’ group per-formed significantly better (p<0.0034) than the ‘voice’ group suggesting the role of interactive visualizations in improved understanding, intuitive knowledge transfer and communication. This paper describes the principles of design, development and potential advances of Sur-Face. Further it also explores the application of serious games in patient education and informed consent process

An innovative virtual reality training tool for orthognathic surgery

Virtual reality (VR) surgery using Oculus Rift and Leap Motion devices is a multi-sensory, holistic surgical training experience. A multimedia combination including 360° videos, three-dimensional interaction, and stereoscopic videos in VR has been developed to enable trainees to experience a realistic surgery environment. The innovation allows trainees to interact with the individual components of the maxillofacial anatomy and apply surgical instruments while watching close-up stereoscopic three-dimensional videos of the surgery. In this study, a novel training tool for Le Fort I osteotomy based on immersive virtual reality (iVR) was developed and validated. Seven consultant oral and maxillofacial surgeons evaluated the application for face and content validity. Using a structured assessment process, the surgeons commented on the content of the developed training tool, its realism and usability, and the applicability of VR surgery for orthognathic surgical training. The results confirmed the clinical applicability of VR for delivering training in orthognathic surgery. Modifications were suggested to improve the user experience and interactions with the surgical instruments. This training tool is ready for testing with surgical trainees

Comprehensive review of foam application during foam assisted water alternating gas (FAWAG) method

© Maxwell Scientific Organization, 2014. In the last few decades, much focus has been placed on enhancing oil recovery from existing fields. This is accomplished by the study and application of various methods. As for recent cases, the Study of fluid mobility control and sweep efficiency in gas injection process as well as Water Alternating Gas (WAG) method have demonstrated positive results on oil recovery and thus gained wide interest in petroleum industry. WAG injection application results in an increased oil recovery. Its mechanism consists in reduction of Gas Oil Ratio (GOR). However, there are some problems associated with this which includes poor volumetric sweep efficiency due to its low density and high mobility when compared with oil. This has led to the introduction of Foam Assisted Water Alternating Gas (FAWAG) technique, which in contrast with WAG injection, acts in improving the sweep efficiency and reducing the gas oil ration therefore maximizing the production rate from the producer wells. This study presents a comprehensive review of FAWAG process from perspective of Snorre field experience. In addition some comparative results between FAWAG and the other EOR methods are presented including their setbacks. The main aim is to provide a solid background for future laboratory research and successful field application-extend

Oculus surgery – an Application of Oculus Rift and Stereoscopic 3D videos in training maxillofacial surgeons

With the continued application of gaming for training and education, which has seen exponential growth over the past two decades, this book offers an insightful introduction to the current developments and applications of game technologies within educational settings, with cutting-edge academic research and industry insights, providing a greater understanding into current and future developments and advances within this field. Following on from the success of the first volume in 2011, researchers from around the world presents up-to-date research on a broad range of new and emerging topics such as serious games and emotion, games for music education and games for medical training, to gamification, bespoke serious games, and adaptation of commercial off-the shelf games for education and narrative design, giving readers a thorough understanding of the advances and current issues facing developers and designers regarding games for training and education. This second volume of Serious Games and Edutainment Applications offers further insights for researchers, designers and educators who are interested in using serious games for training and educational purposes, and gives game developers with detailed information on current topics and developments within this growing area

Multi-Objective Optimisation Method for Posture Prediction and Analysis with Consideration of Fatigue Effect and its Application Case

Automation technique has been widely used in manufacturing industry, but there are still manual handling operations required in assembly and maintenance work in industry. Inappropriate posture and physical fatigue might result in musculoskeletal disorders (MSDs) in such physical jobs. In ergonomics and occupational biomechanics, virtual human modelling techniques have been employed to design and optimize the manual operations in design stage so as to avoid or decrease potential MSD risks. In these methods, physical fatigue is only considered as minimizing the muscle or joint stress, and the fatigue effect along time for the posture is not considered enough. In this study, based on the existing methods and multiple objective optimisation method (MOO), a new posture prediction and analysis method is proposed for predicting the optimal posture and evaluating the physical fatigue in the manual handling operation. The posture prediction and analysis problem is mathematically described and a special application case is demonstrated for analyzing a drilling assembly operation in European Aeronautic Defence & Space Company (EADS) in this paper

Creating New β-Globin-Expressing Lentiviral Vectors by High-Resolution Mapping of Locus Control Region Enhancer Sequences.

Hematopoietic stem cell gene therapy is a promising approach for treating disorders of the hematopoietic system. Identifying combinations of cis-regulatory elements that do not impede packaging or transduction efficiency when included in lentiviral vectors has proven challenging. In this study, we deploy LV-MPRA (lentiviral vector-based, massively parallel reporter assay), an approach that simultaneously analyzes thousands of synthetic DNA fragments in parallel to identify sequence-intrinsic and lineage-specific enhancer function at near-base-pair resolution. We demonstrate the power of LV-MPRA in elucidating the boundaries of previously unknown intrinsic enhancer sequences of the human β-globin locus control region. Our approach facilitated the rapid assembly of novel therapeutic βAS3-globin lentiviral vectors harboring strong lineage-specific recombinant control elements capable of correcting a mouse model of sickle cell disease. LV-MPRA can be used to map any genomic locus for enhancer activity and facilitates the rapid development of therapeutic vectors for treating disorders of the hematopoietic system or other specific tissues and cell types

Effectiveness of immersive virtual reality in surgical training—A randomized control trial

Purpose: Surgical training methods are evolving with the technological advancements, including the application of virtual reality (VR) and augmented reality. However, 28 to 40% of novice residents are not confident in performing a major surgical procedure. VR surgery, an immersive VR (iVR) experience, was developed using Oculus Rift and Leap Motion devices (Leap Motion, Inc, San Francisco, CA) to address this challenge. Our iVR is a multisensory, holistic surgical training application that demonstrates a maxillofacial surgical technique, the Le Fort I osteotomy. The main objective of the present study was to evaluate the effect of using VR surgery on the self-confidence and knowledge of surgical residents. Materials and Methods: A multisite, single-blind, parallel, randomized controlled trial (RCT) was performed. The participants were novice surgical residents with limited experience in performing the Le Fort I osteotomy. The primary outcome measures were the self-assessment scores of trainee confidence using a Likert scale and an objective assessment of the cognitive skills. Ninety-five residents from 7 dental schools were included in the RCT. The participants were randomly divided into a study group of 51 residents and a control group of 44. Participants in the study group used the VR surgery application on an Oculus Rift with Leap Motion device. The control group participants used similar content in a standard PowerPoint presentation on a laptop. Repeated measures multivariate analysis of variance was applied to the data to assess the overall effect of the intervention on the confidence of the residents. Results: The study group participants showed significantly greater perceived self-confidence levels compared with those in the control group (P = .034; α = 0.05). Novices in the first year of their training showed the greatest improvement in their confidence compared with those in their second and third year. Conclusions: iVR experiences improve the knowledge and self-confidence of the surgical residents

Printing of nano- to chip-scale structures for flexible hybrid electronics

Flexible hybrid electronics (FHE) offers potential for fast computation and communication needed in applications such as human–machine interfaces, electronic skin, etc. FHE typically comprises devices that can vary from nano- to chip scale, and their integration using a common process is often challenging. Herein, a printed electronics route is presented to integrate the ultrathin chips (chip-scale) and nanowires (NWs)-based electronic layers (nanoscale) on the same substrate. The fabrication process is categorized into three stages: i) direct transfer printing of ultrathin chips (UTCs), ii) contact printing of nanoscale structures, and iii) metal printing using the direct ink write (DIW) method to define electrodes/interconnects. The UTC printing process is carefully optimized by studying the performance of transistors present on them. Electrical data collected from 14 transistors located on 3 different chips show negligible variation in performance after they are transfer printed—thus confirming the efficacy of the printing technique. The superior grade quality of ZnO-NWs-based electronic layers printed on the same substrate is also demonstrated by constructing UV photodetectors using DIW printing. The photodetectors show high responsivity (≈2 × 107 A W−1) and specific detectivity (≈5 × 1015 Jones) at a low UV intensity of 0.5 µW cm−2

Efficacy of 3D visualization in mobile apps for patient education regarding orthognathic surgery

‘Sur-face’ is an interactive mobile app illustrating different orthognathic surgeries and their potential complications. This study aimed to evaluate the efficacy of Sur-face by comparing two methods of delivering patient information on orthognathic surgeries and their related potential complications: a mobile app with interactive 3D animations and a voice recording containing verbal instructions only. For each method, the participants’ acquired knowledge was assessed using a custom-designed questionnaire. Participants in the ‘app’ group performed significantly better (P<0.0034) than those in the ‘voice’ group and retained more knowledge, suggesting that interactive visualizations play a key role in improving understanding of the orthognathic surgical procedure and its associated complications. This study emphasizes the impact of 3D visualizations in delivering information regarding orthognathic surgery and highlights the advantage of delivering validated patient information through mobile apps

An innovative virtual reality training tool for orthognathic surgery

Virtual reality (VR) surgery using Oculus Rift and Leap Motion devices is a multi-sensory, holistic surgical training experience. A multimedia combination including 360° videos, three-dimensional interaction, and stereoscopic videos in VR has been developed to enable trainees to experience a realistic surgery environment. The innovation allows trainees to interact with the individual components of the maxillofacial anatomy and apply surgical instruments while watching close-up stereoscopic three-dimensional videos of the surgery. In this study, a novel training tool for Le Fort I osteotomy based on immersive virtual reality (iVR) was developed and validated. Seven consultant oral and maxillofacial surgeons evaluated the application for face and content validity. Using a structured assessment process, the surgeons commented on the content of the developed training tool, its realism and usability, and the applicability of VR surgery for orthognathic surgical training. The results confirmed the clinical applicability of VR for delivering training in orthognathic surgery. Modifications were suggested to improve the user experience and interactions with the surgical instruments. This training tool is ready for testing with surgical trainees