11 research outputs found

    PHYTOTAXA

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    Glaucium alakirensis, a small cushion forming perennial from South Anatolia, is described and compared with related species (G. leiocarpum, G. secmenii). The chorology and ecology of the new species and its relatives are discussed. The IUCN threat category Critically Endangered is suggested

    extracts of Convolvulus species

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    The use of plants in the treatment of various diseases has a history as old as humanity. Turkey, with its rich flora, is a unique resource for this kind of investigations. Convolvulaceae genus is used for the prevention of various neurodegenerative diseases and intestinal problems in the traditional folk medicine. It is also reported in the scientific literature that these species possess an inhibition potential for the growth of certain tumor cells. In order to evaluate the potential toxic effects of these species, 1% ethanol extracts were administered to experimental groups and the antioxidant enzyme activities aside from the lipid peroxidation levels were determined in the selected organs. In comparison to control group, a decrease in liver catalase (from 10.69 to 8.61, 7.58 and 5.60 U/mg protein for Convolvulus phrygius, Convolvulus aucheri and Convolvulus galaticus, respectively) and glutathione peroxidase (from 2.21 to 2.12, 0.85 and 0.76 U/mg protein for C. phrygius, C. aucheri and C galaticus, respectively) activities were observed in all groups that were fed with ethanol extract (1%) for a period of one month. A decrease in antioxidant enzyme activities along with the increase in lipid peroxidation levels and blood biochemical parameters is a significant marker of liver injury. Similar results were found for the kidney except from the group fed with C phrygius extract. It is obvious that studied concentrations of Convolvulus species inhibits the liver/kidney antioxidant enzymes in vivo and stimulates the loss of membrane function via peroxidation. Since all these fluctuations in antioxidant enzyme activities cause toxicity in the related organs, further investigations are strongly recommended to find the optimum dose and exposure time prior to medical uses of these species. (C) 2015 Elsevier B.V. All rights reserved

    Festuca albomontana (Poaceae), a new chasmophytic fescue from the Western Taurus Mountains (Antalya, Turkey)

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    A new species of Festuca from the Western Taurus Mountains (Antalya, Turkey) is described here and named F. albomontana. The new species can clearly be distinguished from the other species included in the F. alpina group by its leaf anatomical features. It has a geographically isolated position in the Western Tauruses whereas a closely related species, F. sommieri, is very local in the Black Sea Region of Turkey. It is suggested that it should be in the "critically endangered" threat category according to the International Union for Conservation of Nature (IUCN) criteria. Observations on the ecology of the population are noted. © 2022 Sciendo. All rights reserved.FBA-2018-3773We wish to thank the Akdeniz University Scientific Research Projects Unit (Project number: FBA-2018-3773) for financial support of this study. We also would like to thank the curators of the AKDU, E, G, GJ, MW, W, WU and NMHN for access to specimens

    Apoptosis on Human Breast Cancer Cell Line MCF-7 Cells

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    Conventional and newly emerging treatment procedures such as chemotherapy, catalytic therapy, photodynamic therapy, and radiotherapy have not succeeded in reversing the outcome of cancer diseases to any drastic extent, which has led researchers to investigate alternative treatment options. The extensive repertoire of traditional medicinal knowledge systems from various parts of the world are being re-investigated for their healing properties. It has been reported that several members of the Convolvulaceae, Iridaceae, and Liliaceae families have antitumor activity against some tumor cell lines. Here we first report that Convolvulus galaticus, Crocus antalyensis, and Lilium candidum species have cytotoxic activity on human breast cancer cell line MCF-7 cells. Plant samples were collected and identified, and their cytotoxic effects on the MCF-7 cell line were examined at different concentrations of methanol extracts. We found that all three plants have cytotoxic effects on MCF-7 cells but that C. galaticus has the strongest cytotoxic effect even in the lowest extract concentration tested (0.32 mu g/mL). Our results indicate that these plant extracts have cytotoxic effects on human breast carcinoma cell line MCF-7 cells and that this cytotoxic effect comes from p53-mediated stimulation of apoptosis

    Convolvulus galaticus, Crocus antalyensis, and Lilium candidum extracts show their antitumor activity through induction of p53-mediated apoptosis on human breast cancer cell line MCF-7 cells.

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    Conventional and newly emerging treatment procedures such as chemotherapy, catalytic therapy, photodynamic therapy, and radiotherapy have not succeeded in reversing the outcome of cancer diseases to any drastic extent, which has led researchers to investigate alternative treatment options. The extensive repertoire of traditional medicinal knowledge systems from various parts of the world are being re-investigated for their healing properties. It has been reported that several members of the Convolvulaceae, Iridaceae, and Liliaceae families have antitumor activity against some tumor cell lines. Here we first report that Convolvulus galaticus, Crocus antalyensis, and Lilium candidum species have cytotoxic activity on human breast cancer cell line MCF-7 cells. Plant samples were collected and identified, and their cytotoxic effects on the MCF-7 cell line were examined at different concentrations of methanol extracts. We found that all three plants have cytotoxic effects on MCF-7 cells but that C. galaticus has the strongest cytotoxic effect even in the lowest extract concentration tested (0.32 μg/mL). Our results indicate that these plant extracts have cytotoxic effects on human breast carcinoma cell line MCF-7 cells and that this cytotoxic effect comes from p53-mediated stimulation of apoptosis

    Frequency of norovirus in stool samples from hospitalized children due to acute gastroenteritis in Anatolia, Turkey, 2006-2007

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    Noroviruses are among the most common causes of sporadic enteritis in childhood. In this pilot study, the frequency of norovirus infection in children in mid-western Turkey was investigated from November 2006 to June 2007. Noroviruses were detected in 17% of samples (15/88) by a combination of 2 different RT-PCR assays, both targeting an overlapping region of the RNA-dependent RNA polymerase gene. By sequence analysis, most strains were characterized as GIIb/Hilversum. One strain was characterized as GII.4/2006a, a variant that appeared worldwide in 2006, while another strain was characterized as a rare genotype, GII.6. This study demonstrates the importance of norovirus in paediatric diarrhoea and suggests the heterogeneity of circulating strains in Turkey. © 2009 Informa UK Ltd All rights reserved

    Ipomoea triloba: an alien plant threatening many habitats in Turkey

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    Ipomoea triloba is a plant native to tropical America and has been observed in cotton fields in Antalya Province, Turkey. Ipomoea triloba was identified in 2014 after a warning from the Centre of the Farmers’ Union (Antbirlik). Subsequent field surveys showed that this plant has been considered as a weed by farmers in this region for the last two decades; it has spread in non-agricultural habitats but due to its limited presence did not receive much attention. The spread of I. triloba has increased over the last 5 years to such an extent that it cannot be controlled by existing methods including herbicides. It has established not only in agricultural areas but also in other habitats such as roadsides, irrigation channel edges and coastal regions. This paper provides the first botanical description report of I. triloba in the defined area, an evaluation of environmental and socioeconomic impacts, current status and management activities. Based on all available information the authors concluded that pest risk analysis should be conducted on I. triloba. Furthermore, it should be regarded not only as an environmental weed but also as an agricultural weed and kept under surveillance in Turkey. © 2018 The Authors. Journal compilation © 2018 OEPP/EPP

    Kültürel Mirasın İzinde Ankara

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    Kentlerin belleği vardır. Sokakların, meydanların, binaların, kaldırımların, parkların, taşların ve ağaçların belleği... Cansız bina yığınından ve koşturan insanlardan ibaret gibi görünen kentlerin belleği... Elinizde tuttuğunuz bu kitap, o belleğin taşıyıcısı ve sürdürücüsü olan herkese ve herşeye adanmıştır. Bizi büyüten güzel Ankara'ya vefa borcumuzu ödeme çabasıdır bu derlem. Unutmaya ve unutturmaya karşı direnç, ayrıntılara ve belleğe bir övgüdür... Romanların, şiirlerin, mektupların, binaların, toprağın, heykellerin, yolların ve o yollarda yürüyenlerin içinde sakladığı, unutmadığı her ayrıntıya bir güzellemedir. Bin yılların kentine, Cumhuriyet'in başkentine sevgiyle kaleme alınmış bilimsel yazılardan ve tanıklıklardan meydana gelmiştir. Hacettepe Üniversitesi Tarihi ve Kültürel Mirası Araştırma Merkezi çatısı altında, Ankara'nın belleğine katkıda bulunmaktan mutluluk ve gurur duyuyoruz. Bu derlemin oluşmasına katkıda bulunan yazarlarımıza içtenlikle teşekkür ederiz
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