Elastik Zemine Oturan Fonksiyonel Derecelendirilmiş Kare Bir Plağın Statik Yükler Altında Davranışı

Konferans Bildirisi -- Teorik ve Uygulamalı Mekanik Türk Milli Komitesi, 2015Conference Paper -- Theoretical and Applied Mechanical Turkish National Committee, 2015Bu çalışmada, elastik zemine oturan fonksiyonel derecelendirilmiş (FD) kare bir plağın statik davranışı Ritz yöntemi ile Kirchhoff-Love plak teorisi çerçevesinde incelenmiştir. Ritz yönteminin uygulanması için plak yer değiştirme fonksiyonu kuvvet serisine açılmıştır. Sınır koşulları yer değiştirme fonksiyonuna yardımcı bir fonksiyon ilave edilmesiyle sağlatılmıştır. Çalışmada, farklı malzeme kompozisyonları, farklı sınır koşulları ve elastik zemin parametresinin plağın yer değiştirmeleri ve eksenel normal gerilmeler üzerindeki etkisi incelenmiştir.In this study, the static behavior of a functionally graded (FG) square plate resting on the elastic foundation is investigated via Ritz method within the framework of Kirchhoff-Love plate theory. In order to apply Ritz method, the trial function for the deflection of the plate is expressed in the polynomial form. Boundary conditions are satisfied by adding an auxiliary function to the trial function. The effects of various material compositions, boundary conditions and the parameter of elastic foundation on the deflection and axial normal stress of the plate are examined

Is there a difference between normotensive and hypertensive patients in terms of blood parameters and cardiovascular diseases?

Objectives: It has been stated in various studies that there is a difference in some blood parameters between hypertensive and normotensive patients for a long time. Mean platelet volume (MPV), and red blood cell distribution width (RDW), have been studied in hypertensive patient groups in many studies. Hypertension is a classic risk factor for ischemic stroke and myocardial ischemia, as known. In our study, we examined whether there was a difference between hypertensive patient groups and normotensive patients in terms of blood parameters such as MPV and RDW, and the incidence of stroke and myocardial infarction.Methods: Blood samples and twenty-four-hour ambulatory blood pressure monitoring (ABPM) results of 552 patients admitted to our outpatient clinic with a pre-diagnosis of hypertension were retrospectively analyzed. According to ABPM results, we divided the study participants into four groups; dippers, non-dippers, extreme dippers, and normotansives. Complete blood count and biochemical test results were found in the database of our hospital for all patients and differences between groups were investigated.Results: One hundred seventy three normotensives (Group 1) (mean age, 47.4 ± 15.4 years), 210 non-dippers (Group 2) (mean age, 53.8 ± 15.8 years), 67 extreme dippers (Group 3) (mean age, 49.1 ± 15.9 years) and 102 dippers (Group 4) (mean age, 52.2 ± 12.5 years). Daytime mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) and night-time mean SBP and DBP were significantly different in groups (Group 1: 117 [90-193] mmHg and 71 [55-87] mmHg; Group 2: 137 [107-188] mmHg and 83 [107-188] mmHg; Group 3: 143 [115-193] mmHg and 88 [56-122] mmHg; and Group 4: 140.5 [116-173] mmHg and 76 [55-124] mmHg), p < 0.001; respectively. MPV and RDW levels were different in all four groups (p < 0.001). We found a significant difference in the rates of stroke and coronary artery disease between the four groups (p = 0.018 and p = 0.002, respectively). In the ROC curve analysis MPV had sensitivity of %77. 8 and specificity of 78. 1% for stroke when the cut-off value MPV was 9.25 (Area under curve: 0.808, 95% confidence interval: 0.726-0.889, p < 0.001).Conclusions: In our study, MPV and RDW levels and the rates of stroke and cardiovascular disease were significantly higher in non-dipper patients compared to other groups

Cytotoxic activity and docking studies of 2-arenoxybenzaldehyde N-acyl hydrazone and 1,3,4-oxadiazole derivatives against various cancer cell lines

To understand whether previously synthesized novel hydrazone and oxadiazole derivatives have promising anticancer effects, docking studies and in vitro toxicity assays were performed on A-549, MDA-MB-231, and PC-3 cell lines. The antiproliferative properties of the compounds were investigated using molecular docking experiments. Each compound's best-docked poses, binding affinity, and receptor-ligand interaction were evaluated. Compounds' molecular weights, logPs, TPSAs, abilities to pass the blood-brain barrier, GI absorption qualities, and CYPP450 inhibition have been given. When the activities of these molecules were examined in vitro, for the A-549 cell line, hydrazone 1e had the minimum IC50 value of 13.39 mu M. For the MDA-MB-231 cell line, oxadiazole 2l demonstrated the lowest IC50 value, with 22.73 mu M. For PC-3, hydrazone 1d showed the lowest C50 value of 9.38 mu M. The three most promising compounds were determined as compounds 1e, 1d, and 2a based on their minimum IC50 values, and an additional scratch assay was performed for A-549 and MDA-MB-231 cells, which have high migration capacity, for the three most potent molecules; it was determined that these molecules did not show a significant antimetastatic effect

Predictive Values of Inflammation Indexes in Predicting Mortality in Patients with COVID 19 Hospitalized in General Intensive Care Unit

Objective: Causing a global pandemic, the coronavirus disease 2019 (COVID-19) has caused millions of people to become infected and many more to die. In this study we aimed to investigate whether routinely evaluated clinical and laboratory values ??can predict the mortality of patients with COVID-19 disease.Materials and Methods: In our study, routine laboratory parameters of 89 patients hospitalized in the general intensive care unit with the diagnosis of COVID 19 were retrospectively analyzed. The aggregate index of systemic inflammation (AISI) and other inflamatuar values were calculated from blood tests in patients with positive COVID-19 polymerase chain reaction test and with ground-glass opacity on lung tomography. Patients were divided into two groups as those who died (non-survivors) and those who were discharged (survivors)during the intensive care follow-ups. Results: In our study, in 48 patients who died during follow-up, the indexes of AISI, other inflamatuar paramaters and the biochemical parameters such as troponin I, d-dimer, ferritin and procalcitonin were significantly higher than in discharged patients. Hypertension and higher AISI and ferritin levels were statistically associated with reduced survival in Cox regression analysis (Hazard ration (HR): 3.176; 95% Confident interval (CI): 1.122-8.991, p=0.03, HR: 1.114; 95% CI: 1.060-1.348, p=0.042, HR=1.072;95% CI: 1.014-1.242, p=0.011, respectively.Conclusion: Inflammation indexes derived from blood tests and acute phase reactants such as ferritin can guide us in planning the treatment strategy and risk stratification in patients with COVID-19 in intensive care follow-ups.

Helicobacter pylori infection in amniotic fluid may cause hyperemesis gravidarum

Objectives: Limited data are available from recent trials involving pregnant women to guide Helicobacter pylori infection diagnosis. There are no data about the presence of H. pylori in the amniotic fluid as well. Furthermore, the relation between amniotic fluid H. pylori and hyperemesis gravidarum (HG) has not been characterized yet. Materials and Methods: This is a prospective study conducted after obtaining approval from the Ethics Committee. Pregnant women undergoing amniocentesis were enrolled in the study. The stool antigen test assessed the presence of H. pylori in amniotic fluid. A perinatologist independently performed an amniocentesis. The obtained amniotic liquid was sent to the laboratory to evaluate H. pylori infection by stool H. pylori antigen assay. We determined the rate of H. pylori in amniotic fluid and assessed relations between H. pylori infection and pregnancy outcome, including HG. Results: Between May and September 2017, we enrolled 48 pregnant women who underwent amniocentesis to detect possible fetal malformations. Patients were divided into two groups regarding the HG status. There were significant differences between the groups in terms of H. pylori infection presence. Among them, 28 (58.3%) were found to have a positive H. pylori test in their amniotic fluid. The rate of HG was significantly higher (71.4%) in patients who tested positive for H. pylori in amniocentesis than the H. pylori-negative group (20%), (p<0.001). Conclusions: The study’s main new finding is that presence of H. pylori in the amniotic fluid is possible. Our data suggest that H. pylori-infected amniotic fluid is associated with the experience of past HG. The current study may have important implications for HG detection and help identify patients who would benefit from future preventive strategies. © 2020 Global Research Online. All rights reserved

Effect of circumcision for the prevention of recurrent urinary tract infection

ıdrar yolu enfeksiyonu çocukluk çağında önemli bir problem olup tedavi edilmezse etken mikroorganizma alt üriner sistemden yukarıya doğru çıkarak böbrek yetmezliğine kadar ilerleyen bir seyir izleyebilir. Önemli bir idrar yolu enfeksiyonu kaynağı sünnet derisidir. Çalışmamızın amacı sünnetin idrar yolu enfeksiyonunu önlemedeki etkinliğinin araştırılmasıdır. Çalışma grubumuzu, yineleyen idrar yolu enfeksiyonu bulguları ile başvuran sünnet olmamış erkek çocuklar oluşturdu. Hastalardan idrar kültürü alınıp enfeksiyon varsa, antibiyoterapi uygulandı. Antibiyoterapi sonrasında idrar yolu enfeksiyonu yineleyen çocuklara Ultrasonografi, Miksion Sisto Üretrografisi, ıntra Venöz Pyelografi veDMSAgibi ileri görüntüleme tetkikleri yapıldıktan sonra sünnet uygulanıp, hastalar sünnet sonrası idrar kültürü ile tekrar değerlendirildi. Çalışmamızda toplam 12 hasta olup ortalama yaş 2.4 idi. Hastaların idrarlarında E.Coli, Pseudomonas, Proteus, Stafilokok, Enterokok Klebsiella ve Salmonella gibi mikroorganizmalar üredi. Hastaların biri dışında hiçbirinde sünnet sonrası idrar kültüründe üreme olmadı. Yineleyen idrar yolu enfeksiyonu olan sünnetsiz çocuklarda sünnet derisi taşıyıcılığı araştırılmalı ve sünnetin tedavinin bir parçası olduğu düşünülmelidir.Urinary tract infection (UTI) is an important problem of childhood and if left untreated, the microorganisms may migrate from the lower urinary system to upper levels, leading to chronic renal failure. A UTI source of considerable importance is preputial skin. This study was performed to identify the role of circumcision on prevention of recurrent UTI. Study group consisted of uncircumcised male children diagnosed as recurrent UTI. Following diagnostic tests such as ultrasonography, voiding cystourethrography, intravenous pyelography and DMSA, circumcision was performed. Postcircumcision evaluation was made by urine culture. Total number of patients in our study group was 12 with a mean age of 2.4 years. Urine cultures before circumcision revealed microorganisms such as E. Coli, Pseudomonas, Proteus, Staphylococcus, Enterococcus, Klebsiella and Salmonella species. None of the urine cultures revealed a microbial growth in patients at the postcircumcision period. In uncircumcised children with recurrent urinary tract infections, the carrier state of preputial skin must be investigated, and circumcision must be accounted for as a step of treatment procedur

Effects of immunosuppressive drugs on COVID-19 severity in patients with autoimmune hepatitis

Background: We investigated associations between baseline use of immunosuppressive drugs and severity of Coronavirus Disease 2019 (COVID-19) in autoimmune hepatitis (AIH). Patients and methods: Data of AIH patients with laboratory confirmed COVID-19 were retrospectively collected from 15 countries. The outcomes of AIH patients who were on immunosuppression at the time of COVID-19 were compared to patients who were not on AIH medication. The clinical courses of COVID-19 were classified as (i)-no hospitalization, (ii)-hospitalization without oxygen supplementation, (iii)-hospitalization with oxygen supplementation by nasal cannula or mask, (iv)-intensive care unit (ICU) admission with non-invasive mechanical ventilation, (v)-ICU admission with invasive mechanical ventilation or (vi)-death and analysed using ordinal logistic regression. Results: We included 254 AIH patients (79.5%, female) with a median age of 50 (range, 17-85) years. At the onset of COVID-19, 234 patients (92.1%) were on treatment with glucocorticoids (n = 156), thiopurines (n = 151), mycophenolate mofetil (n = 22) or tacrolimus (n = 16), alone or in combinations. Overall, 94 (37%) patients were hospitalized and 18 (7.1%) patients died. Use of systemic glucocorticoids (adjusted odds ratio [aOR] 4.73, 95% CI 1.12-25.89) and thiopurines (aOR 4.78, 95% CI 1.33-23.50) for AIH was associated with worse COVID-19 severity, after adjusting for age-sex, comorbidities and presence of cirrhosis. Baseline treatment with mycophenolate mofetil (aOR 3.56, 95% CI 0.76-20.56) and tacrolimus (aOR 4.09, 95% CI 0.69-27.00) were also associated with more severe COVID-19 courses in a smaller subset of treated patients. Conclusion: Baseline treatment with systemic glucocorticoids or thiopurines prior to the onset of COVID-19 was significantly associated with COVID-19 severity in patients with AIH.Fil: Efe, Cumali. Harran University Hospita; TurquíaFil: Lammert, Craig. University School of Medicine Indianapolis; Estados UnidosFil: Taşçılar, Koray. Universitat Erlangen-Nuremberg; AlemaniaFil: Dhanasekaran, Renumathy. University of Stanford; Estados UnidosFil: Ebik, Berat. Gazi Yasargil Education And Research Hospital; TurquíaFil: Higuera de la Tijera, Fatima. Hospital General de México; MéxicoFil: Calışkan, Ali R.. No especifíca;Fil: Peralta, Mirta. Gobierno de la Ciudad de Buenos Aires. Hospital de Infecciosas "Dr. Francisco Javier Muñiz"; ArgentinaFil: Gerussi, Alessio. Università degli Studi di Milano; ItaliaFil: Massoumi, Hatef. No especifíca;Fil: Catana, Andreea M.. Harvard Medical School; Estados UnidosFil: Purnak, Tugrul. University of Texas; Estados UnidosFil: Rigamonti, Cristina. Università del Piemonte Orientale ; ItaliaFil: Aldana, Andres J. G.. Fundacion Santa Fe de Bogota; ColombiaFil: Khakoo, Nidah. Miami University; Estados UnidosFil: Nazal, Leyla. Clinica Las Condes; ChileFil: Frager, Shalom. Montefiore Medical Center; Estados UnidosFil: Demir, Nurhan. Haseki Training And Research Hospital; TurquíaFil: Irak, Kader. Kanuni Sultan Suleyman Training And Research Hospital; TurquíaFil: Melekoğlu Ellik, Zeynep. Ankara University Medical Faculty; TurquíaFil: Kacmaz, Hüseyin. Adıyaman University; TurquíaFil: Balaban, Yasemin. Hacettepe University; TurquíaFil: Atay, Kadri. No especifíca;Fil: Eren, Fatih. No especifíca;Fil: Alvares da-Silva, Mario R.. Universidade Federal do Rio Grande do Sul; BrasilFil: Cristoferi, Laura. Università degli Studi di Milano; ItaliaFil: Urzua, Álvaro. Universidad de Chile; ChileFil: Eşkazan, Tuğçe. Cerrahpaşa School of Medicine; TurquíaFil: Magro, Bianca. No especifíca;Fil: Snijders, Romee. No especifíca;Fil: Barutçu, Sezgin. No especifíca;Fil: Lytvyak, Ellina. University of Alberta; CanadáFil: Zazueta, Godolfino M.. Instituto Nacional de la Nutrición Salvador Zubiran; MéxicoFil: Demirezer Bolat, Aylin. Ankara City Hospital; TurquíaFil: Aydın, Mesut. Van Yuzuncu Yil University; TurquíaFil: Amorós Martín, Alexandra Noemí. No especifíca;Fil: De Martin, Eleonora. No especifíca;Fil: Ekin, Nazım. No especifíca;Fil: Yıldırım, Sümeyra. No especifíca;Fil: Yavuz, Ahmet. No especifíca;Fil: Bıyık, Murat. Necmettin Erbakan University; TurquíaFil: Narro, Graciela C.. Instituto Nacional de la Nutrición Salvador Zubiran; MéxicoFil: Bıyık, Murat. Uludag University; TurquíaFil: Kıyıcı, Murat. No especifíca;Fil: Kahramanoğlu Aksoy, Evrim. No especifíca;Fil: Vincent, Maria. No especifíca;Fil: Carr, Rotonya M.. University of Pennsylvania; Estados UnidosFil: Günşar, Fulya. No especifíca;Fil: Reyes, Eira C.. Hepatology Unit. Hospital Militar Central de México; MéxicoFil: Harputluoğlu, Murat. Inönü University School of Medicine; TurquíaFil: Aloman, Costica. Rush University Medical Center; Estados UnidosFil: Gatselis, Nikolaos K.. University Hospital Of Larissa; GreciaFil: Üstündağ, Yücel. No especifíca;Fil: Brahm, Javier. Clinica Las Condes; ChileFil: Vargas, Nataly C. E.. Hospital Nacional Almanzor Aguinaga Asenjo; PerúFil: Güzelbulut, Fatih. No especifíca;Fil: Garcia, Sandro R.. Hospital Iv Víctor Lazarte Echegaray; PerúFil: Aguirre, Jonathan. Hospital Angeles del Pedregal; MéxicoFil: Anders, Margarita. Hospital Alemán; ArgentinaFil: Ratusnu, Natalia. Hospital Regional de Ushuaia; ArgentinaFil: Hatemi, Ibrahim. No especifíca;Fil: Mendizabal, Manuel. Universidad Austral; ArgentinaFil: Floreani, Annarosa. Università di Padova; ItaliaFil: Fagiuoli, Stefano. No especifíca;Fil: Silva, Marcelo. Universidad Austral; ArgentinaFil: Idilman, Ramazan. No especifíca;Fil: Satapathy, Sanjaya K.. No especifíca;Fil: Silveira, Marina. University of Yale. School of Medicine; Estados UnidosFil: Drenth, Joost P. H.. No especifíca;Fil: Dalekos, George N.. No especifíca;Fil: N.Assis, David. University of Yale. School of Medicine; Estados UnidosFil: Björnsson, Einar. No especifíca;Fil: Boyer, James L.. University of Yale. School of Medicine; Estados UnidosFil: Yoshida, Eric M.. University of British Columbia; CanadáFil: Invernizzi, Pietro. Università degli Studi di Milano; ItaliaFil: Levy, Cynthia. University of Miami; Estados UnidosFil: Montano Loza, Aldo J.. University of Alberta; CanadáFil: Schiano, Thomas D.. No especifíca;Fil: Ridruejo, Ezequiel. Universidad Austral; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; ArgentinaFil: Wahlin, Staffan. No especifíca

'Regulating' Fundamental Rights And Freedoms By Decrees In Ordinary Times According To The 1982 Turkish Constitution

Hukukumuzda, Bakanlar Kuruluna kanun hükmünde kararname (KHK) çıkarma yetkisi, ilk olarak, 1961 Anayasasında (m.64) tanınmıştır. 1982 Anayasasında da (m.91/1), önceki Anayasadaki hükme benzer bir şekilde KHK düzenlenmiş ve KHK yürütme organının düzenleyici işlemleri arasında sayılmıştır. Anayasanın 91. maddesinde, olağan dönem KHK'lerinin "düzenleme alanı" belirtilmektedir. Buna göre, sıkıyönetim ve olağanüstü haller saklı kalmak üzere, Anayasanın ikinci kısmının birinci ve ikinci bölümlerinde yer alan temel haklar, kişi hakları ve ödevleri ile dördüncü bölümünde yer alan siyasal haklar ve ödevler KHK'lerle düzenlenemez. Buna karşılık, Anayasanın ikinci kısmının üçüncü bölümünde yer alan sosyal ve ekonomik haklar ve ödevlerin, KHK ile düzenlenmesi konusunda herhangi bir yasaklama öngörülmemektedir. Bu çalışmada, olağan dönem KHK'leri ile temel hak ve ödevlerin "düzenlenmesi" konusu incelenmektedir. Bu bağlamda, temel haklar ve ödevler alanında KHK'lerle düzenleme yapılmasının sınırları üzerinde durulmaktadır.The power to issue decrees was, for the first time, granted to the Council of Ministers by article 64 of the Turkish Constitution of 1961. As the 1961 Constitution, the 1982 Constitution lays down provisions on the decrees in art. 91 (1) of the 1982 Constitution and the decrees, inter alia, are regarded regulative power of the executive organ of the State. "Regulative scope" of the decrees is stated in article 91 of the 1982 Constitution. Accordingly, with the exceptions of martial law and states of emergency, decrees cannot be issued to regulate the fundamental rights, individual rights and duties included in the first and second chapters and the political rights and duties listed in the fourth chapter of the second part of the Constitution. However, there are no restrictions with regard to social and economic rights and duties which are laid down in the third chapter of the second part of the 1982 Constitution. This study deals with regulating of fundamental rights and freedoms in the ordinary times. In this regard, limits of the decrees, on fundamental rights and freedoms, are touched upon

The Concept of "Freedom to Claim Rights" in the Decisions of the Constitional Court of Turkey

Bu çalışmada, Anayasa Mahkemesi'nin Anayasa'nın 36. maddesinde düzenlenen "hak arama özgürlüğü" konusuna yaklaşımı incelenmiştir. Hak arama özgürlüğünün kapsamının belirlenmesinde, Anayasa Mahkemesi'nin 1961 ve 1982 Anayasası dönemlerinde verdiği kararlar göz önüne alınmıştır. Anayasa Mahkemesi'nce, "bireyin adaleti bulma, hakkı olanı elde etme ve haksızlığı giderme uğraşının uygar yöntemi" şeklinde tarif edilen hak arama özgürlüğü, hukuk devletinin başlıca ölçütlerinden, demokrasinin en çağdaş gereklerinden ve vazgeçilmez koşullarından biri olarak kararlara yansımıştır. Anayasa Mahkemesi genel olarak, hak arama özgürlüğünü geniş bir çerçeveden ele almıştır. Böylece, hak arama özgürlüğünün kullanımını sınırlayan düzenlemeler, Anayasa'ya aykırı bulunarak iptal edilmiştir. Ancak, hak arama özgürlüğünün kullanımını açıkça sınırlayan bir takım yasal düzenlemelerin, yerindelik denetimi yoluyla, Anayasa'ya uygun bulunduğu da görülmektedir. Söz konusu yaklaşım şekli, hak arama özgürlüğünün sınırlanması sonucunu doğurmuştur.The aim of this study is to evaluate the Constitutional Court's approach to the concept of "freedom to claim rights" as provided by Article 36 of the Turkish Constitution. The Constitutional Court's decisions, by reference to the 1961 and the 1982 Constitution, are taken as examples to define the concept of freedom to claim rights. According to the Court, freedom to claim rights may be defined as seeking justice by individuals, to obtain what is just and fair for the individual and a contemporary way to eliminate unfairness. It may justly be said the concept has been employed in the decisions to proof that it is one of the most remarkably elements of democracy in where rule of law is applied and it is one of the unavoidable elements of democracy. The Court, in general, interpreters the concept widely. Therefore, legal rules that conflict with the concept are revoked. However, some legal rules that apparently conflict with the concept have not been revoked. The Court decided that they have not been in conflict with the Constitution. Such an approach has inevitably resulted in the limitation of the concept

The examination of constitutional amendments in terms of their form according to the 1982 constitution

1982 Anayasasında (m. 175, 148), Türkiye Büyük Millet Meclisine anayasa deği- şikliği yapma, Anayasa Mahkemesine de söz konusu anayasa değişikliklerini şekil bakımından denetleme yetkisi tanınmıştır. Anayasa Mahkemesinin anayasa değişikliklerini denetleme yetkisi, Anayasada öngörülen bazı şekil şartlarıyla sınırlı tutulmuştur: “Teklif ve oylama çoğunluğu” ve “ivedilikle görüşülememe”. 9.2.2008 tarih ve 5735 sayılı Kanunla, Anayasanın 10. ve 42. maddesinde yapılan Anayasa Değişiklikleri, Anayasa Mahkemesi tarafından iptal edilmiştir. Söz konusu Anayasa Değişikliklerinin denetiminde, “teklif ve oylama çoğunluğu” ve “ivedilikle görüşülememe” şartlarıyla sınırlı bir denetimin yapılmadığı görülmektedir. Başka bir deyişle, 5735 sayılı Kanunla gerçekleştirilen Anayasa Değişiklikleri, Anayasanın değiştirilmesi teklif edilemeyen ilk üç maddesine aykırılık nedeniyle iptal edilmiştir. Böylece, şekil görüntüsü altında, esas bakımından bir denetim yapılmıştır. Bu çalışmada, Anayasa Mahkemesinin anayasa değişikliklerini şekil bakımından denetleme yetkisi ve bu yetkinin sınırı üzerinde durulmaktadır.The 1982 Constitution (articles 175 and 148) has granted Turkish National Assembly the right to amend the constitution and authorized the Constitutional Court to examine amendments with regard to their form. The Court is entitled to declare such amendments null and void. The scope of the Courts examination is restricted to consideration of whether an amendment meet certain criteria with regard to form prescribed by the Constitution, that are whether the requisite majorities were obtained for the proposal and in the ballot, and whether the prohibition on debates under urgent procedure was complied with. The Law 5735, dated 9.2.2008 and amended the articles 10 and 42 of the Constitution, has been declared null and void by the Constitutional Court following its examination by the Court in respect of its form. The relevant Court decision has not established the failure of the Law 5735 to meet the criteria of obtaining the requisite majorities for the proposal and in the ballot and the prohibition on debates under urgent procedure. The Courts decision has pointed out that the Law 5735 was declared unconstitutional on the ground that it contravened the provisions of the three irrevocable articles of the Constitution, effectively amounting the Courts decision to the examination and veri&#64257; cation of the constitutional amendment with regard to substance. This study dwells on the scope of Constitutional Courts authority to review constitutional amendments with regard to form