Kinetics of Particles Adsorption Processes Driven by Diffusion

The kinetics of the deposition of colloidal particles onto a solid surface is analytically studied. We take into account both the diffusion of particles from the bulk as well as the geometrical aspects of the layer of adsorbed particles. We derive the first kinetic equation for the coverage of the surface (a generalized Langmuir equation) whose predictions are in agreement with recent simulation results where diffusion of particles from the bulk is explicitly considered.Comment: 4 page

Suppression of electron spin decoherence of the diamond NV center by a transverse magnetic field

We demonstrate that the spin decoherence of nitrogen vacancy (NV) centers in diamond can be suppressed by a transverse magnetic field if the electron spin bath is the primary decoherence source. The NV spin coherence, created in "a decoherence-free subspace" is protected by the transverse component of the zero-field splitting, increasing the spin-coherence time about twofold. The decoherence due to the electron spin bath is also suppressed at magnetic fields stronger than ~25 gauss when applied parallel to the NV symmetry axis. Our method can be used to extend the spin-coherence time of similar spin systems for applications in quantum computing, field sensing, and other metrologies.Comment: 20 pages, 4 figure

Particle-Based Mesoscale Hydrodynamic Techniques

Dissipative particle dynamics (DPD) and multi-particle collision (MPC) dynamics are powerful tools to study mesoscale hydrodynamic phenomena accompanied by thermal fluctuations. To understand the advantages of these types of mesoscale simulation techniques in more detail, we propose new two methods, which are intermediate between DPD and MPC -- DPD with a multibody thermostat (DPD-MT), and MPC-Langevin dynamics (MPC-LD). The key features are applying a Langevin thermostat to the relative velocities of pairs of particles or multi-particle collisions, and whether or not to employ collision cells. The viscosity of MPC-LD is derived analytically, in very good agreement with the results of numerical simulations.Comment: 7 pages, 2 figures, 1 tabl

Dissipative Particle Dynamics with Energy Conservation

The stochastic differential equations for a model of dissipative particle dynamics with both total energy and total momentum conservation in the particle-particle interactions are presented. The corresponding Fokker-Planck equation for the evolution of the probability distribution for the system is deduced together with the corresponding fluctuation-dissipation theorems ensuring that the ab initio chosen equilibrium probability distribution for the relevant variables is a stationary solution. When energy conservation is included, the system can sustain temperature gradients and heat flow can be modeled.Comment: 7 pages, submitted to Europhys. Let

A reduced model for shock and detonation waves. II. The reactive case

We present a mesoscopic model for reactive shock waves, which extends a previous model proposed in [G. Stoltz, Europhys. Lett. 76 (2006), 849]. A complex molecule (or a group of molecules) is replaced by a single mesoparticle, evolving according to some Dissipative Particle Dynamics. Chemical reactions can be handled in a mean way by considering an additional variable per particle describing a rate of reaction. The evolution of this rate is governed by the kinetics of a reversible exothermic reaction. Numerical results give profiles in qualitative agreement with all-atom studies

Mapping monthly rainfall data in Galicia (NW Spain) using inverse distances and geostatistical methods

In this paper, results from three different interpolation techniques based on Geostatistics (ordinary kriging, kriging with external drift and conditional simulation) and one deterministic method (inverse distances) for mapping total monthly rainfall are compared. The study data set comprised total monthly rainfall from 1998 till 2001 corresponding to a maximum of 121 meteorological stations irregularly distributed in the region of Galicia (NW Spain). Furthermore, a raster Geographic Information System (GIS) was used for spatial interpolation with a 500×500 m grid digital elevation model. Inverse distance technique was appropriate for a rapid estimation of the rainfall at the studied scale. In order to apply geostatistical interpolation techniques, a spatial dependence analysis was performed; rainfall spatial dependence was observed in 33 out of 48 months analysed, the rest of the rainfall data sets presented a random behaviour. Different values of the semivariogram parameters caused the smoothing in the maps obtained by ordinary kriging. Kriging with external drift results were according to former studies which showed the influence of topography. Conditional simulation is considered to give more realistic results; however, this consideration must be confirmed with new data

Linear Operator Inequality and Null Controllability with Vanishing Energy for unbounded control systems

We consider linear systems on a separable Hilbert space $H$, which are null controllable at some time $T_0>0$ under the action of a point or boundary control. Parabolic and hyperbolic control systems usually studied in applications are special cases. To every initial state $y_0 \in H$ we associate the minimal "energy" needed to transfer $y_0$ to $0$ in a time $T \ge T_0$ ("energy" of a control being the square of its $L^2$ norm). We give both necessary and sufficient conditions under which the minimal energy converges to $0$ for $T\to+\infty$. This extends to boundary control systems the concept of null controllability with vanishing energy introduced by Priola and Zabczyk (Siam J. Control Optim. 42 (2003)) for distributed systems. The proofs in Priola-Zabczyk paper depend on properties of the associated Riccati equation, which are not available in the present, general setting. Here we base our results on new properties of the quadratic regulator problem with stability and the Linear Operator Inequality.Comment: In this version we have also added a section on examples and applications of our main results. This version is similar to the one which will be published on "SIAM Journal on Control and Optimization" (SIAM

Thy-1 (CD90)-Induced Metastatic Cancer Cell Migration and Invasion Are β3 Integrin-Dependent and Involve a Ca²⁺/P2X7 Receptor Signaling Axis.

Cancer cell adhesion to the vascular endothelium is an important step in tumor metastasis. Thy-1 (CD90), a cell adhesion molecule expressed in activated endothelial cells, has been implicated in melanoma metastasis by binding to integrins present in cancer cells. However, the signaling pathway(s) triggered by this Thy-1-Integrin interaction in cancer cells remains to be defined. Our previously reported data indicate that Ca <sup>2+</sup> -dependent hemichannel opening, as well as the P2X7 receptor, are key players in Thy-1-α <sub>V</sub> β <sub>3</sub> Integrin-induced migration of reactive astrocytes. Thus, we investigated whether this signaling pathway is activated in MDA-MB-231 breast cancer cells and in B16F10 melanoma cells when stimulated with Thy-1. In both cancer cell types, Thy-1 induced a rapid increase in intracellular Ca <sup>2+</sup> , ATP release, as well as cell migration and invasion. Connexin and Pannexin inhibitors decreased cell migration, implicating a requirement for hemichannel opening in Thy-1-induced cell migration. In addition, cell migration and invasion were precluded when the P2X7 receptor was pharmacologically blocked. Moreover, the ability of breast cancer and melanoma cells to transmigrate through an activated endothelial monolayer was significantly decreased when the β <sub>3</sub> Integrin was silenced in these cancer cells. Importantly, melanoma cells with silenced β <sub>3</sub> Integrin were unable to metastasize to the lung in a preclinical mouse model. Thus, our results suggest that the Ca <sup>2+</sup> /hemichannel/ATP/P2X7 receptor-signaling axis triggered by the Thy-1-α <sub>V</sub> β <sub>3</sub> Integrin interaction is important for cancer cell migration, invasion and transvasation. These findings open up the possibility of therapeutically targeting the Thy-1-Integrin signaling pathway to prevent metastasis