49 research outputs found
an analysis
Water footprint (WF) reflects how
efficiently water has been utilized in the production
cycle of a particular product or service. Under the
production conditions of the farm of the Faculty of
Agriculture, University of Ruhuna, Sri Lanka studied,
the WF of Chicken Egg was calculated as 3734 m3/ton.
Other than drinking and servicing water, feed water
accounted over 99% of the WF of egg production. It
is concluded that through appropriate interventions,
both at policy and industry level, water footprint of egg
production systems can be lowered substantially
A First-Principles Computational Study of Structural and Elastic Properties of ZnO
The purpose of this study is to determine structural and mechanical properties of zinc oxide (ZnO) using first-principles computational methods. ZnO is a semiconductor widely used in many electronic and optical applications. ZnO is also economically and environmentally desirable – first, both the constituent elements are abundant on Earth and therefore inexpensive for large-scale applications; second, it is non- toxic. The most significant contribution of this study is the simulations of the high-pressure phases. These high-pressure simulations are important because the rock salt phase of ZnO obtained at high pressure can be recovered at ambient pressure, and this new structural phase possesses different properties that may be more useful for certain applications
McNair Research Journal - Summer 2015
Journal articles based on research conducted by undergraduate students in the McNair Scholars Program
Table of Contents
Biography of Dr. Ronald E. McNair
Statements:
Dr. Neal J. Smatresk, UNLV President
Dr. Juanita P. Fain, Vice President of Student Affairs
Dr. William W. Sullivan, Associate Vice President for Retention and Outreach
Mr. Keith Rogers, Deputy Executive Director of the Center for Academic Enrichment and Outreach
McNair Scholars Institute Staf
The role of melanin pathways in extremotolerance and virulence of <em>Fonsecaea</em> revealed by <em>de novo</em> assembly transcriptomics using illumina paired-end sequencing
AbstractMelanisation has been considered to be an important virulence factor of Fonsecaea monophora. However, the biosynthetic mechanisms of melanisation remain unknown. We therefore used next generation sequencing technology to investigate the transcriptome and digital gene expression data, which are valuable resources to better understand the molecular and biological mechanisms regulating melanisation in F. monophora. We performed de novo transcriptome assembly and digital gene expression (DGE) profiling analyses of parent (CBS 122845) and albino (CBS 125194) strains using the Illumina RNA-seq system. A total of 17 352 annotated unigenes were found by BLAST search of NR, Swiss-Prot, Gene Ontology, Clusters of Orthologous Groups and Kyoto Encyclopedia of Genes and Genomes (KEGG) (E-value <1e‒5). A total of 2 283 unigenes were judged to be the differentially expressed between the two genotypes. We identified most of the genes coding for key enzymes involved in melanin biosynthesis pathways, including polyketide synthase (pks), multicopper oxidase (mco), laccase, tyrosinase and homogentisate 1,2-dioxygenase (hmgA). DEG analysis showed extensive down-regulation of key genes in the DHN pathway, while up-regulation was noted in the DOPA pathway of the albino mutant. The transcript levels of partial genes were confirmed by real time RT-PCR, while the crucial role of key enzymes was confirmed by either inhibitor or substrate tests in vitro. Meanwhile, numbers of genes involved in light sensing, cell wall synthesis, morphology and environmental stress were identified in the transcriptome of F. monophora. In addition, 3 353 SSRs (Simple Sequence Repeats) markers were identified from 21 600 consensus sequences. Blocking of the DNH pathway is the most likely reason of melanin deficiency in the albino strain, while the production of pheomelanin and pyomelanin were probably regulated by unknown transcription factors on upstream of both pathways. Most of genes involved in environmental tolerance to oxidants, irradiation and extreme temperatures were also assembled and annotated in transcriptomes of F. monophora. In addition, thousands of identified cSSR (combined SSR) markers will favour further genetic linkage studies. In conclusion, these data will contribute to understanding the regulation of melanin biosynthesis and help to improve the studies of pathogenicity of F. monophora
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Modeling the Quantum Behavior of Hydrogen using Density Functional Theory, Quantum Monte Carlo, and Machine Learning
Computation and simulation play a central role in physics. As applied to atoms, molecules, and condensed-matter systems, this is based on quantum mechanics. Many calculations are only possible though due to approximations made. Two of particular interest in this dissertation are the consideration of static and classical ions (nuclei) and the use of pseudopotentials to replace the divergent Coulomb interaction between ions and electrons. For many systems, these approximately work or are expected to work well. There are others though where things are less clear. Dense hydrogen is one such system, and one that is both rich in physics and has the potential for significant practical applications.In this dissertation, the aforementioned approximations as made in perhaps the most-used computational method, density-functional theory, and as applied to dense hydrogen are investigated. This includes the effect of the pseudopotential approximation on the phase diagram and superconductivity of solid hydrogen and also the nuclear quantum states of molecular hydrogen adsorbed to a surface. For the latter, quantum Monte Carlo is used in a novel way that supplements density-functional theory. As a supplemental study, a reduction of the computational cost of density-functional theory, from to where is the number of electrons, is considered using machine learning. Altogether, these results are expected to be significant for computational physics, the field of dense hydrogen, and other fields such a
Economic parameters in nutritional studies
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