化学プラントにおける遠隔協動作業支援作業情報共有システム

首都大学東京, 2018-03-25, 博士（工学）首都大学東

"Double eyes” sign of congenital bilateral dacryocystoceles

Dacryocystocele is caused by nasolacrimal duct obstruction and results in cystic dilatation of the proximal part of the nasolacrimal duct, which is located inferomedial to the orbit, leading to fluid accumulation. It is important to consider that persistent congenital bilateral dacryocystoceles may cause neonatal nasal obstruction resulting in respiratory difficulty, and large dacryocystoceles may require surgical drainage. Ultrasonography demonstrates that congenital bilateral dacryocystoceles and normal eyeballs prenatally resemble two pairs of cystic "lesions” of different sizes. We herein present a case of prenatally diagnosed isolated congenital bilateral dacryocystoceles and propose the new name of "double eyes” sign for this rare condition to create an impact on medical students and resident

Safety technologies and people/organizations activities for the next generation : Safety management and safety information sharing system for supporting industrial safety

Ensuring a sustainable safety management system is a global issue and a social demand. In recent years, Risk Based Safety Management (RBSM) has become mainstream as a comprehensive management system for handling process safety in Oil & Gas industries. Nowadays, UK Safety Case concept was well established, and this concept is widely applied in various industries. Through this process, logical safety assurance approach was developed and introduced, named CAE (Claims, Arguments, and Evidences) . In Japan, Oil & Gas industry operators keen to apply Risk Based Process Safety Management which is suggested by AIChE CCPS. However, actual implementation of RBPS is not straightforward since detailed approach is not well defined yet. The UK Nuclear Industry\u27s Safety Case approach may be able to assist implementing Risk Based Process Safety Management System in the Japanese O&G industry. Furthermore, it has been developing work support and information sharing technologies in the industrial field by introducing DX (Digital Transformation) technology. This paper introduces topics to improve industrial safety using these two approaches, and discusses safety technologies and people / organizations that will support the next generation of plants

Study protocol for a multi-center, randomized controlled trial to develop Japanese denture adhesive guidelines for patients with complete dentures : the Denture Adhesive Guideline trial : study protocol for a randomized controlled trial

Background: Denture adhesives, characterized as medical products in 1935 by the American Dental Association, have been considered useful adjuncts for improving denture retention and stability. However, many dentists in Japan are hesitant to acknowledge denture adhesives in daily practice because of the stereotype that dentures should be inherently stable, without the aid of adhesives. The aim of this study is to verify the efficacy of denture adhesives to establish guidelines for Japanese users. The null hypothesis is that the application of denture adhesives, including the cream and powder types, or a control (isotonic sodium chloride solution) would not produce different outcomes nor would they differentially improve the set outcomes between baseline and day 4 post-application. Methods: This ten-center, randomized controlled trial with parallel groups is ongoing. Three hundred edentulous patients with complete dentures will be allocated to three groups (cream-type adhesive, powder-type adhesive, and control groups). The participants will wear their dentures with the denture adhesive for 4 days, including during eight meals (three breakfasts, two lunches, and three dinners). The baseline measurements and final measurements for the denture adhesives will be performed on the first day and after breakfast on the fourth day. The primary outcome is a general satisfaction rating for the denture. The secondary outcomes are denture satisfaction ratings for various denture functions, occlusal bite force, resistance to dislodgement, masticatory performance, perceived chewing ability, and oral health-related quality of life. Between-subjects comparisons among the three groups and within-subjects comparisons of the pre- and post-intervention measurements will be performed. Furthermore, a multiple regression analysis will be performed. The main analyses will be based on the intention-to-treat principle. A sample size of 100 subjects per group, including an assumed dropout rate of 10 %, will be required to achieve 80 % power with a 5 % alpha level. Discussion: This randomized clinical trial will provide information about denture adhesives to complete denture wearers, prosthodontic educators, and dentists in Japan. We believe this new evidence on denture adhesive use from Japan will aid dentists in their daily practice even in other countries

総合科学科におけるキャリア教育を軸としたグローバル人材育成の試み : SGH3年目における1年次生の学年経営実践報告

学年経営は日々の指導の積み重ねによって成される。これさえ行えば何もかもうまく行くというような秘策はない。担任副担任でチームを組み、生徒集団を複数の目で見守りながら、授業や行事を展開していく。本年次は本校総合科学科20年余りの歴史が築きあげたキャリア教育を大切にしながら、スーパーグローバルハイスクール(SGH) の目標であるグローバル人材の育成に向けて取り組んできた。本稿ではその1年間の取り組みについて報告する

平成29年度「T-GAP」実践報告 : ソーシャル・アクション型授業の開発と実践

ソーシャル・アクションに取り組む学校が増えつつある。国際バカロレア・ディプロマプログラムのCAS活動もそうだが、生徒自らが社会課題を設定し、その解決に向けてアクションを起こすことが期待される。国際的には社会的起業(Social Enterpreneurship)が注目される中、高校生がソーシャル・アクションに取り組む意義は大きい。そのため、本校は2年次にてグループでソーシャル・アクションに取り組むための授業として「T-GAP : つくさかグローバル・アクション・プロジェクト」という授業を開発した。本小論は、SGHに指定されて以来、開発を重ねてきた成果を報告する

Use of the index of pulmonary vascular disease for predicting long-term outcome of pulmonary arterial hypertension associated with congenital heart disease

AimsLimited data exist on risk factors for the long-term outcome of pulmonary arterial hypertension (PAH) associated with congenital heart disease (CHD-PAH). We focused on the index of pulmonary vascular disease (IPVD), an assessment system for pulmonary artery pathology specimens. The IPVD classifies pulmonary vascular lesions into four categories based on severity: (1) no intimal thickening, (2) cellular thickening of the intima, (3) fibrous thickening of the intima, and (4) destruction of the tunica media, with the overall grade expressed as an additive mean of these scores. This study aimed to investigate the relationship between IPVD and the long-term outcome of CHD-PAH.MethodsThis retrospective study examined lung pathology images of 764 patients with CHD-PAH aged <20 years whose lung specimens were submitted to the Japanese Research Institute of Pulmonary Vasculature for pulmonary pathological review between 2001 and 2020. Clinical information was collected retrospectively by each attending physician. The primary endpoint was cardiovascular death.ResultsThe 5-year, 10-year, 15-year, and 20-year cardiovascular death-free survival rates for all patients were 92.0%, 90.4%, 87.3%, and 86.1%, respectively. The group with an IPVD of ≥2.0 had significantly poorer survival than the group with an IPVD <2.0 (P = .037). The Cox proportional hazards model adjusted for the presence of congenital anomaly syndromes associated with pulmonary hypertension, and age at lung biopsy showed similar results (hazard ratio 4.46; 95% confidence interval: 1.45–13.73; P = .009).ConclusionsThe IPVD scoring system is useful for predicting the long-term outcome of CHD-PAH. For patients with an IPVD of ≥2.0, treatment strategies, including choosing palliative procedures such as pulmonary artery banding to restrict pulmonary blood flow and postponement of intracardiac repair, should be more carefully considered